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Clinical Trials


             Division of Rheumatology and Immunology Clinical Research Staff:

                                                                   

 

              Holly Steigelman, CCRP, MACPR                             Kelly Morris

              Lead Clinical Research Coordinator                            Clinical Research Assistant 

               Phone: 614-685-6987                                                 Phone: 614-685-8068

               Holly.Steigelman@osumc.edu                                    Kelly.Morris@osumc.edu    

 

 

 


Currently enrolling pharmaceutical clinical trials and investigator-initiated trials:

Principal Investigator- Wael Jarjour, MD

The Ohio State University Rheumatology and Immunology Biorepository     

 

This study is being done to provide resources for future studies involving rheumatic disorders. The samples and data collected will be stored and used in the future to learn more about rheumatic and autoimmune disorders. 

 

Sponsor: The Ohio State University Department of Rheumatology                            

 

Stress Moderation Impacting Lupus with Exercise (S.M.I.L.E.): Using Tai Chi to explore the effects of daily moderate exercise and stress reduction in patients with Systemic Lupus Erythematosus

 

This study is being done to see if completing a Tai chi program (combining moderate exercise and stress reduction) can help patients with lupus. Originally developed for self-defense, Tai chi has evolved into a graceful form of exercise. It is used for stress reduction and a variety of health conditions. This form of exercise is often described as meditation in motion since it promotes serenity through gentle, flowing movements.

 

Sponsor: The OSU Center for Integrative Health and Wellness, Division of Immunology and Rheumatology, and Rheumatology Research Foundation (RRF)

 

Biomarkers in Autoimmune Disease

 

This study is being done to identify markers in the blood of patients with inflammatory diseases, individuals with degenerative arthritis, and healthy volunteers.

Sponsor: Department of Rheumatology

Biomarkers in Synovial Fluid

This study is being done to identify markers in synovial fluid, synovial tissue (fluid/tissue in the joints), other tissue, and blood to measure disease activity of patients who are being treated for arthritic conditions with hopes to find new targets for treatment.

Sponsor: Department of Rheumatology

 

Multi-Source Examinations of Biomarkers in Autoimmune Diseases

 

This study is being done to learn more about biological markers in people with autoimmune disorders and in healthy volunteers. These studies can help us to understand more about autoimmune diseases.

Sponsor: Department of Rheumatology

If you would like to participate in one of Dr. Jarjour’s trials please contact Holly Steigelman at 614-685-6987


 

Principal Investigator- Stacy Ardoin, MD

Lupus, Vasculitis, and Glomerulonephritis (LVG) Registry

The purpose of this registry is to collect medical information (data), blood, saliva, and urine specimens and follow outcomes on persons with lupus, vasculitis and/or glomerulonephritis. This study is being done to help researchers who are involved in the diagnosis and treatment of these medical conditions to better understand these diseases and their management, including the long term safety and effectiveness of various treatments. Your samples and data will be used for future research on lupus, vasculitis, and glomerulonephritis.

Sponsor: Division of Rheumatology and Immunology

If you would like to participate in one of Dr. Ardoin’s trials please contact Holly Steigelman at 614-685-6987

 


Principal Investigator- Ali Ajam, MD

A phase II study to evaluate subcutaneous abatacept vs. placebo in diffuse cutaneous systemic sclerosis—a double-blind, placebo-controlled, randomized controlled trial

 

The purpose of this clinical research study is to evaluate the safety and effectiveness of treatment with abatacept (Orencia) 125mg injected subcutaneously versus placebo (a substance with no active ingredients and therefore may have no treatment benefit) in subjects with diffuse systemic scleroderma (or diffuse systemic sclerosis). The effectiveness will be assessed primarily by the modified Rodnan Skin Score (mRSS) which measures how tight or soft your skin is.

Sponsor: University of Michigan

 

Scleroderma Registry

 

The purpose of the Ohio State Scleroderma Registry is to collect data, blood, and skin biopsies from people with scleroderma. This study is being done to help researchers who are involved in the diagnosis and treatment of this medical condition to better understand the disease and its management, including the long term safety and effectiveness of various treatments. Your samples will be used for future research on scleroderma.

Sponsor: Division of Rheumatology and Immunology

If you would like to participate in one of Dr. Ajam’s trials please contact Holly Steigelman at 614-685-6987


Principal Investigator- Alexa Meara, MD

Assessing Disease Comprehension in Patients with Lupus

 

The goal of this study is to assess the understanding that people with lupus have about their disease.

 

Sponsor: The Ohio State University

 

Assessing Healthy Literacy, Numeracy, and Patient Activation in Healthy Friends and Family of Patients with Lupus

 

The goal of this study is to assess the educational skill set of healthy individuals by measuring health literacy, numeracy, and patient activation. 

 

Sponsor: The Ohio State University

If you would like to participate in one of Dr. Meara’s trials please contact Holly Steigelman at 614-685-6987

 

 


Principal Investigator- Kevin Hackshaw, MD

Spectrophotometric Fingerprint for Central Sensitivity Syndromes

The purpose of this study is to help improve our ability to diagnose chronic pain syndromes for which no diagnostic biomarker is available. A diagnostic biomarker is a test that can predict or determine whether someone is affected by a particular condition.

Sponsor: Department of Rheumatology

If you would like to participate in one of Dr. Hackshaw’s trials please contact Holly Steigelman at 614-685-6987