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Dan N. Spetie, MD

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395 W 12th Ave
Columbus, OH 43210

Phone: (614) 293-4997

Email: spetie.1@osu.edu


Current OSU Appointments

Associate Professor-Clinical, Nephrology

Physician, FGP-Nephrology



1998 - present Diplomat: American Board of Internal Medicine
2000 - present Diplomat: American Board of Nephrology

Chapters in Books

The Ohio State University Nephrology Fellows' Manual. "The Ohio State University Nephrology Fellows' Manual." In The Ohio State University Nephrology Fellows' Manual. -. Columbus, OH, US|USA: The Ohio State Univeristy Division of Nephrology, June 2000.

D. N. Speite, L. U. Haller, A. K. Agarwal. "Updates in Nephrology. A Summary of common clinical diasnoses encountered in the clinical practice.." In Clinics in Podiatric Medicine and Surgery. 43-64. Maryland Heights, US|USA: Elsevier, January 2002.

Spetie DN, Agarwal AK. "Clinical Assessment of Renal Function." In Textbook of Nephrology for the Asian Pacific Physicians. Edited by A Mandal, AK Agarwal. -. New Delhi: Jaypee Brothers, January 2004.

Spetie DN, Agarwal AK. "Metabolic Acidosis." In Textbook of Nephrology for the Asian Pacific Physicians. Edited by A Mandal, AK Agarwal. -. New Delhi: Jaypee Brothers, January 2004.



1984 B.S., Saint Sava National College

1991 M.D., Carol Davila University of Medicine and Pharmacy

1998 M.D., The Ohio State University

2000 None Indicated, The Ohio State University



2004 - present Award for Dedicated Service.
2005 - present Award for Dedicated Service.

Journal Articles

Koudriakova, T; Iatsimirskaia, E; Tulebaev, S; Spetie, D; Utkin, I; Mullet, D; Thompson, T; Vouros, P; Gerber, N. "In vivo disposition and metabolism by liver and enterocyte microsomes of the antitubercular drug rifabutin in rats.." The Journal of pharmacology and experimental therapeutics. Vol. 279, no. 3. (January 1996.): 1300-9.

Hebert, L, A; Spetie, D, N; Keane, W F. "The urgent call of albuminuria/proteinuria. Heeding its significance in early detection of kidney disease.." Postgraduate medicine. Vol. 110, no. 4. (January 2001.): 79-82, 87.

Spetie, Dan, N; Haller, Lisa, U; Agarwal, Anil K. "Updates in nephrology. A summary of common diagnoses encountered in the clinical practice.." Clinics in podiatric medicine and surgery. Vol. 19, no. 1. (January 2002.): 43-64, vi.

Spetie, Dan, N; Tang, Yuxiao; Rovin, Brad, H; Nadasdy, Tibor; Nadasdy, Gyongyi; Pesavento, Todd, E; Hebert, Lee A. "Mycophenolate therapy of SLE membranous nephropathy.." Kidney international. Vol. 66, no. 6. (January 2004.): 2411-5.

Rovin, Brad, H; Tang, Yuxiao; Sun, Junfeng; Nagaraja, Haikady, N; Hackshaw, Kevin, V; Gray, Linda; Rice, Robert; Birmingham, Daniel, J; Yu, Chack-Yung; Spetie, Dan, N; Aziz, Amy; Hebert, Lee A. "Clinical significance of fever in the systemic lupus erythematosus patient receiving steroid therapy.." Kidney international. Vol. 68, no. 2. (January 2005.): 747-59.

Hebert, Lee, A; Rovin, Brad, H; Agarwal, Anil, K; Spetie, Dan N. "Cyclophosphamide or chlorambucil therapy is indicated in idiopathic membranous nephropathy with strong risk factors for progression.." American journal of kidney diseases : the official journal of the National Kidney Foundation. Vol. 45, no. 4. (January 2005.): 788-9; author replyy 789.

AK Singh, L Szczech, KL Tang, H Barnhart, S Sapp, M Wolfson, D Reddan, for the CHOIR investigators, including DN Spetie. "Correction of Anemia with Epoetin Alfa in Chronic Kidney Disease." The New England Journal of Medicine. Vol. 355, (November 2006.): 2085-2098.

Spetie, Dan, N; Nadasdy, Tibor; Nadasdy, Gyongyi; Agarwal, Garima; Mauer, Michael; Agarwal, Anil, K; Khabiri, Hooman; Nagaraja, Haikady, N; Nahman, N Stanley Jr; Hartman, Judith, A; Hebert, Lee A. "Proposed pathogenesis of idiopathic loin pain-hematuria syndrome.." American journal of kidney diseases : the official journal of the National Kidney Foundation. Vol. 47, no. 3. (January 2006.): 419-27.

RJ Hogg, L Fitzgibbons, C Atkins, N Nardelli, RC Bay, for the North American IgA Nephropathy Study Group, including DN Spetie. "Efficacy of Omega-3 Fatty Acids in Children and Adults with IgA Nephropathy Is Dosage- and Size-Dependent." Clinical Journal of the American Society of Nephrology. Vol. 1, (November 2006.): 1167-1172.

RQ Hu, H Mehter, T Nadasdy, A Satoskar, DN Spetie, BH Rovin, and L Hebert. "Severe Hemorrhagic CystitisAssociated with Oral Cyclophosphamide Therapy: case report and literature review." Rheumatology International. Vol. 28, (January 2008.): 1161-1164.

LA Hebert, DN Spetie, C Benedetti. "Clinical review of the Loin Pain Hematuria Syndrome." Up To Date. (May 2008.): -.

Alison McKinley, Edward Park, Dan Spetie, Kevin Hackshaw, Smitha Nagaraja, Lee Hebert, Brad Rovin. "Oral Cyclophosphamide for Lupus Glomerulonephritis: An Underused Therapeutic Option.." Oral Cyclophosphamide for Lupus Glomerulonephritis: An Underused Therapeutic Option.. Vol. 4, no. 11. (November 2009.): 1754-1760.


Reference Works

January 1995 Spetie DN, Tulebaev S, Collins J, Gerber N, Koudriakova T."Evidence for Metabolism of Rifabutin In Vivo and In Vitro by CYP3A of Liver and Enterocytes" .
January 1995 Koudriakova T, Spetie DN, Ukin I, Apseloff G, Gerber N.."Pharmacokinetics of Rifabutin in the Rat" .
January 1995 Collins J, Choe S, Spetie DN, Mullet D, Koudriakova T, Gerber N, Apseloff G.."Lack of Effect of Cigarette Smoking on the Pharmacokinetics of Rifabutin." .
January 1998 Long DE, Spetie DN, Irsik RD, Nahman NS."Effect of Balloon Angioplasty on Progression of Renal Insufficiency in Patients with Atherosclerotic Renal Artery Stenosis." .
January 1999 Spetie DN, Long DE, Parsons C, Nahman NS."Balloon Angioplasty Versus Conservative Management in Patients with Renal Artery Stenosis." .
January 2000 Dan N Spetie, Alexander Y Afanasyev, Todd E Pesavento, Michael E Falkenhain, Ronald M Ferguson, and Fernando G Cosio."Pyelonephritis (PYELO) In Renal Allografts Is Frequently Clinically Silent" .
January 2000 D.N. Spetie, T.E. Pesavento, E.A. Elkhammas, M.L. Henry, F.G. Cosio."Pancreas Allograft Survival In Simultaneous Pancreas-Kidney (SPK) Recipients: The Link Between K And P Grafts" .
January 2000 D.N. Spetie, F.G. Cosio, L.U. Haller, W.L. Frankel, R.P. Pelletier, T.E. Pesavento."Evidence For Glomerular Disease During Acute Renal Allograft Rejection" .
January 2003 Lee A. Hebert, Tibor Nadasdy, Garima Agarwal, Giongy Nadasdy, N. Stanley Nahman, Jr., Dan N. Spetie, Haikady N. Nagaraja."Idiopathic Loin Pain Hematuria Syndrome (LPHS) Is a Glomerular Disorder" .
January 2004 Lee A. Hebert, Brad H. Rovin, Daniel J. Birmingham, Chack Yung-Yu, Dan N. Spetie."Clinical Significance of Fever in the SLE Patient Receiving Steroid Therapy" .
January 2004 L. A. Hebert, T. Nadasdy, G. Agarwal, M. Mauer, A. K. Agarwal, G. Nadasdy, D. N. Spetie, N. S. Nahman."Proposed Diagnostic Criteria and Classification of Loin Pain Hematuria Syndrome (LPHS) Based on Kidney Biopsy in 83 Patients" .
January 2005 AK Agarwal, G Agarwal, S Seth, JA Hartman, D Spetie, and LA Hebert."Sodium ThioSulphate: A New Therapy For Loin Pain Hematuria Syndrome (LPHS)." .
January 2006 T Nadasdy, G Nadasdy, G Agarwal, A Satoskar, M Mauer, A Agarwal, D Spetie, BH Rovin, LA Hebert."Idiopathic Thick Glomerular Basement Membrane Nephropathy (IThGBMN): A Newly Recognized Cause of Glomerular Hematuria" .
November 2008 D.N. Spetie, B. Knudsen, F. Coe, J. Hartman, LA Hebert.."High Incidence of Kidney Stone Risk Factors in Patients with Idiopathic Loin Pain Hematuria Syndrome (LPHS)." Philadelphia.


May 2008 Hebert, Lee MD. Spetie, Dan MD.."Loin Pain Hematuria Syndrome" UP TO DATE

Professional Activities

2005 - present Television interview regarding nocturnal dialysis program at Ohio State University. WBNS 10TV.