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John Gunn, PhD


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460 W 12th Ave
Columbus, OH 43210

Phone: (614) 292-6036

Email: gunn.43@osu.edu

 

Current OSU Appointments

Professor, SBS-Microbial Infectn/Immunity

Professor, Microbiology Admin

Professor, Internal Medicine

Vice Chair, SBS-Microbial Infectn/Immunity

 

Biographical

Our Salmonella research relates to: (1) in vivo induced LPS modifications and their effect on bacterial innate immune resistance and bacterial/LPS recognition by the host, (2) the establishment and maintenance of the asymptomatic carriage state of Salmonella spp. in the human gallbladder. Our Francisella work is focused on understanding regulatory factors important to virulence gene induction, intramacrophage survival and virulence. In addition, we are interested in the biology and role in virulence of the four Francisella acid phosphatases. Regarding both Salmonella and Francisella spp, we are investigating new live, attenuated vaccines and small molecule therapeutics to advance treatment/prevention of disease.

Academic Advising

present Suzanne Keller, The Ohio State University.
present Amy Schindler, The Ohio State University. Graduated 2000.
present Amanda Reeber, The Ohio State University.
present Branden Yonke, The Ohio State University.
present Jessica Miles, The Ohio State University. Graduated 2002.
present Kimberly Mackie, The Ohio State University. Graduated 2002.
1998 - present Eric Ashton, University of Texas Health Science Center at San Antonio.
1999 - present Andrea Fuessel, University of Notre Dame.
1999 - present Amanda Carroll, University of Texas Health Science Center at San Antonio. Graduated 2004.
2000 - present Dustin Smart, Texas A&M University.
2004 - present Robert Crawford, The Ohio State University.
2004 - present Brian Wulff, The Ohio State University.
2005 - present Mamta Singh, The Ohio State University.
2005 - present Amanda Beltramini, The Ohio State University.
2005 - present David Ravneberg, The Ohio State University.
2007 - present Chris Garton, The Ohio State University.
2007 - present Asia Johnson, The Ohio State University.
2007 - present Shilpa Soni, The Ohio State University.
2009 - present Paul Sample, The Ohio State University.
2009 - present Jessica Napolitano, The Ohio State University.
2009 - present Monica Ramos, Rice University.
2009 - present Joanna Marshall, The Ohio State University. Graduated 2013.
2010 - present Kesha Wilford, University of Texas Health Science Center at San Antonio. Graduated 2001.
2010 - present Maddy Gerber, The Ohio State University.
2011 - present Shipan Dai, The Ohio State University.
2011 - present Tadesse Eguale, Addis Ababa University.
2011 - present Brian Bullard, The Ohio State University.
2011 - present Susan Richards, The Ohio State University.
2005 Brian Bell, The Ohio State University. Graduated 0.
2006 Amanda Reeber, The Ohio State University. Graduated 0.
2007 Jacob Posner, Upper Arlington High School. Graduated 0.
2007 Joshua Cyktor, The Ohio State University. Graduated 0.
2007 Stephen Vadia, The Ohio State University. Graduated 0.
2008 Jessica Mates, The Ohio State University. Graduated 2014.
2008 Kristin Reeve, The Ohio State University. Graduated 0.
2009 Nathan Dissinger, The Ohio State University. Graduated 0.
2009 Ran Dong, The Ohio State University. Graduated 0.
2010 Devyn Gillette, The Ohio State University. Graduated 0.
2011 Jacob Koopman, The Ohio State University. Graduated 0.
2012 Jasmine Moshiri, The Ohio State University. Graduated 0.
2012 Michael Niger, The Ohio State University. Graduated 0.
2012 Shirley Luong, The Ohio State University. Graduated 0.
2012 Adam Rauckhorst, The Ohio State University. Graduated 0.
2012 Ky Hoang, The Ohio State University. Graduated 0.
2012 Rebecca Allen, The Ohio State University. Graduated 0.
2012 Christine Fahy, The Ohio State University. Graduated 0.
2012 Jessica Zimmerer, The Ohio State University. Graduated 0.
2012 Rebecca Rings, The Ohio State University. Graduated 0.
2012 Jennifer Edwards, The Ohio State University. Graduated 0.
2012 Jonathan P., The Ohio State University. Graduated 0.
2012 Patrick Grierson, The Ohio State University. Graduated 0.
2013 Melanie Benchic, The Ohio State University. Graduated 0.
2013 Sasha Adamovich, The Ohio State University. Graduated 0.
2013 Vijayaramu Dirisala, The Ohio State University. Graduated 0.
2013 Allison Birney, The Ohio State University. Graduated 0.
2013 Dominique Olds, The Ohio State University. Graduated 0.
2013 Olivia Harder, The Ohio State University. Graduated 0.
1997 - 2000 Sara Ryan, University of Texas Health Science Center at San Antonio.
2000 Scott Allen, University of Texas Health Science Center at San Antonio.
2000 Shonna McBride, University of Texas Health Science Center at San Antonio.
1998 - 2003 Angela Prouty, University of Texas Health Science Center at San Antonio.
2002 - 2003 Ana Vallor, The Ohio State University.
2002 - 2003 Joe Mammarappallil, University of Texas Health Science Center at San Antonio. Graduated 2003.
2003 Allison Abplanalp, University of Texas Health Science Center at San Antonio.
1999 - 2004 Rita Tamayo, University of Texas Health Science Center at San Antonio. Graduated 2004.
2004 - 2005 Massimo Merighi, The Ohio State University.
2004 - 2005 Japheth Pritchett, The Ohio State University. Graduated 0.
2005 - 2007 Aditi Bhatiya, The Ohio State University. Graduated 2007.
2007 Benjamin Reiss, University of Pennsylvania. Graduated 0.
2007 - 2008 Megan Conroy, The Ohio State University. Graduated 0.
2004 - 2009 Corey Clay, The Ohio State University. Graduated 2009.
2004 - 2009 Robert Crawford, The Ohio State University. Graduated 2009.
2005 - 2009 Brian Bell, The Ohio State University.
2006 - 2011 Susan Richards, The Ohio State University.
2010 - 2011 Hans Meisen, The Ohio State University. Graduated 0.
2010 - 2011 Mia Tazi, The Ohio State University. Graduated 0.
2004 - 2012 Nrusingh Mohapatra, The Ohio State University. Graduated 2012.
2009 - 2012 Kristi Strandberg, The Ohio State University.
2009 - 2012 Nicholas Jarjour, The Ohio State University. Graduated 2012.
2008 - 2013 Geoffrey Gonzalez-Escobedo, The Ohio State University. Graduated 2013.
2009 - 2013 Chris Jones, The Ohio State University. Graduated 2013.
2011 - 2013 Stephen Deptola, The Ohio State University. Graduated 0.
2013 Carolyn Lee, The Ohio State University. Graduated 0.
 

Chapters in Books

GENETIC-CHARACTERIZATION OF NEISSERIAL RESTRICTION MODIFICATION SYSTEMS

Mechanisms of bacterial resistance to antimicrobial peptides

The Structure and Function of Francisella LPS

The Interaction of Bile Salts with Pathogenic and Non-Pathogenic Intestinal Bacteria

Salmonella Resistance and Response to Bile: A Key in vivo Signal

The Interaction of Bile Salts with Pathogenic and Non-Pathogenic Intestinal Bacteria

Salmonella-regulated lipopolysaccharide modifications

Salmonella Biofilms: From Food to Human Disease,

Salmonella Biofilms: From Food to Human Disease

Francisella tularensis: Regulation of gene expression, intracellular trafficking and subversion of host defenses.

In vitro modeling of gallbladder-associated salmonella spp. Colonization

Salmonella Resistance and Response to Bile: A Key in vivo Signal

In vitro modeling of gallbladder-associated Salmonella spp. colonization

 

Conferences

Genetic characterization of Neisserial restriction/modification systems

RESTRICTION AND MODIFICATION SYSTEMS OF NEISSERIA-GONORRHOEAE

Short-term movement and behaviour of black marlin Makaira indica in the Coral Sea as determined through a pop-up satellite archival tagging experiment

Salmonella typhimurium down-regulates the host innate immune response by inducing lipopolysaccharide lipid A structural modifications

 

Degrees

1988 B.S., Bowling Green State University

1993 Ph.D., University of Maryland

 

Editorial Activities

2000 Sealy Grant Program, University of Texas Medical Branch at Galveston
2000 - 2003 NIGMS Review Panel for MBRS grants
2001 NIH Study Section for RFA HD-00-018
2001 Army In-house Laboratory Independent Research (ILIR) Program
2002 Louisiana Board of Regents Support Fund R&D Program
2002 Kansas Biomedical Research Infrastructure Network
2002 - 2004 James McLaughlin Fellowship Fund (UTMB)
2004 USUHS In-House Research Award
2004 NIAID Bacteriology-Mycology 1 (BM-1)
2004 National Science Foundation (NSF)
2004 - 2005 NIAID BACP (new BM-1)
2005 Special Emphasis Panel ZRG1 IDM-J 03
2005 - 2009 NIAID BACP Study Section, member
2007 NIAID BACP-B (09) F Special Emphasis Panel, Chair
2010 - present Proceedings of the National Academy of Sciences
2010 - present Applied and Environmental Microbiology
2010 - present PLoS Pathogens
2010 - present Plasmid
2010 - present International Journal of Antimicrobial Agents
2010 - present Infection and Immunity
2010 - present Infection and Immunity
2010 - present Molecular Microbiology
2010 - present Microbes and Infection
2010 - present Journal of Biological Chemistry
2010 - present Journal of Bacteriology
2010 - present Journal of Antimicrobial Chemotherapy
2010 - present FEMS Microbiology and Immunology
2010 - present FEBS Letters
2010 - present Journal of Infectious Disease
2010 - present The European Journal of Biochemistry
2010 Cellular Microbiology
2010 Biofouling
2010 Antimicrobial Agents and Chemotherapy
2010 Trends in Microbiology
2010 Special Emphasis Panel ZGM1 MBRS-X (GC)
2010 Science
2010 Nature Reviews Microbiology
2010 Nature
2010 Molecular Microbiology
2010 JOVe
2010 Journal of Molecular Medicine
2010 Journal of Immunology
2010 Frontiers in Microbiology
2010 Frontiers in Cellular and Infection Microbiology
2010 Proceedings of the National Academy of Sciences
2010 PLOS Genetics
2011 Special Emphasis Panel ZRG1 IDM S (02), Alternate Chair
2011 NIH IRIDA ZRG1 IDM-R (50)
2012 NIH ZAI1-JKB-J1
2013 ZA1-AI-SM-J1
 

Honors

1987 - 1988 BGSU Undergraduate Research Award.
1987 - 1988 James D. Graham Scholarship (Outstanding Student in Molecular Biology).
1987 - 1988 Phi Beta Kappa. Bowling Green State University.
1991 Andrew J. Moyer Award (Outstanding Microbiology Graduate Student).
1993 - 1995 Microbial Pathogenesis Training Grant Recipient.
2002 Nominated for Dean's Award for Exceptional Teaching.
2004 Tzagournis Medical Research Fund Award.
2005 - present Infection and Immunity Editorial Board Member. Infection and Immunity.
2007 - present Keynote Speaker, 16th Annual Philadelphia Infection and Immunity Forum.
2009 - present Nominated for John T. and Ruth Weimer Mount Award, Sphinx and Mortar Board Honorary.
2009 - present Associate Editor, Frontiers in Cellular and Infection Microbiology.
2009 - present Journal of Bacteriology Editorial Board.
2009 - present Nominated: OSU Alumni Award for Distinguished Teaching.
2009 - present Nominated: Distinguished Undergraduate Research Mentor of the Year.
2009 - 2010 OSU Beckman Scholars Grant: 1 of 3 Biomedical Science Mentors.
2010 - present Journal of Bacteriology Editorial Board Member. Journal of Bacteriology.
2012 - present Nominated for Ohio State University College of Medicine Distinguished Professor Award. Ohio State University College of Medicine.
2013 - present Nominated: OSU Alumni Award for Distinguished Teaching. The Ohio State University.
2013 - present Editorial Board Member. PLOS One.
 

Journal Articles

"Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes." INFECTION AND IMMUNITY. Vol. 75, no. 7. (July 2007.): -.

"Regulation of Virulence Gene Transcripts by the Francisella novicida Orphan Response Regulator PmrA: Role of Phosphorylation and Evidence of MglA/SspA Interaction." INFECTION AND IMMUNITY. Vol. 78, no. 5. (May 2010.): -.

 

Reference Works

May 1998 VanVelkinburgh JC, Gunn JS."Characterization of PhoP-and PmrA regulated gene promoters" .
August 1998 Tekulve R, Edwards R, Smith P, Gunn J, Miller S, Groisman E, Spector M."Genetic characterization of starvation-inducible resistance to the antimicrobial peptide polymyxin in Salmonella typhimurium" .
September 1998 Gunn JS, Baker SJ, Morona R."PmrA-PmrB regulated modifications of LPS" .
May 1998 VanVelkinburgh JC, Gunn JS."Characterization of PhoP-and PmrA regulated gene promoters" .
January 1998 Gunn JS."PmrA-PmrB regulated modifcation of LPS" .
August 1998 Tekulve R, Edwards R, Smith P, Gunn J, Miller S, Groisman E, Spector M."Genetic characterization of starvation-inducible resistance to the antimicrobial peptide polymyxin in Salmonella Typhimurium" .
May 1999 Ryan SS, Gunn JS."Characterization of the PmrA-PmrB Regulon in Salmonella typhimurium" .
January 1999 Lang AM, Van Velkinburgh JC, Gunn JS."Identification of Salmonella Loci Necessary for Resistance to Bile" .
January 1999 Gunn JS."Texas Branch ASM" .
January 1999 Gunn JS."Characterization of Proteus mirabilis and Burkholderia cepacia Mechanisms of Resistance to IB-367" .
September 1999 Gunn JS, VanVelkinburgh JC, Lang AM."Identification of Salmonella Loci Necessary for Resistance to Bile" .
September 1999 Gunn JS, Velkinburgh CV, Lang AM."Identification of salmonella loci necessary for resistance to bile" .
November 1999 Lang AM, Velkinburgh V, Gunn JS."Identification of salmonella loci necessary for resistance to bile" .
January 1999 Gunn JS."Salmonella’s interactions with bile: Mechanisms of resistance and effect on invasion of epithelial cells" .
May 1999 Ryan SS, Gunn JS."Characterization of the PmrA-PmrB Regulon in Salmonella typhimurium" .
May 2000 Gunn JS."Resistance of Salmonella to Intestinal Antimicrobials" .
May 2000 Lang AM, Gunn JS."Salmonella typhimurium invasion is repressed in the presence of bile" .
May 2000 Lang AM, Gunn JS."Salmonella typhimurium invasion is repressed in the presence of bile" .
January 2000 Gunn JS."The Role of The PhoPQ/PmrAB Two-Component Regulatory Cascade in Salmonella virulence" .
May 2000 Lang AM, Gunn JS."Salmonella typhirmurium invasion is repressed in the presence of bile" .
May 2000 Gunn JS."Co-Convener of Tissue-Specific Expression of Virulence Genes Session" .
May 2000 McCoy AJ, Gunn JS, Liu H, Falla TJ."Identification and Characterization of Proteus mirabilis Mutants" .
May 2000 McCoy AJ, Gunn JS, Liu H,Falla TJ."Identification and characterization of Proteus mirabilis mutant sensitive to antimicrobial peptides" .
January 2000 Lang AM, Gunn JS."Salmonella typhimurium invasion is repressed in the presence of bile" .
May 2001 Prouty AM, Gunn JS."The formation of biofilms on gallstones by Salmonella spp" .
January 2001 Prouty AM, Gunn JS."The formation of biofilms on gallstones by Salmonella spp" .
January 2001 Tamayo R, Ryan SS, McCoy AJ, Gunn JS."Identification and characterization of Salmonella typhimurium PmrA-PmrB regulated genes and genes necessary for polymyxin resistance" .
January 2001 Carroll A, Gunn JS."Identification and characterization of a novel two-component regulatory system in Salmonella typhimurium" .
May 2001 Gunn JS, McCoy AJ, Tran L, Liu H, Falla T."Identification and Characterization of Burkholderia cepacia Mutants Sensitive to Antimicrobial Peptides" .
January 2001 Tamayo R, Ryan SS, McCoy AJ, Gunn JS."Identification and chracterization of Salmonella typhimurium PmrA-PmrB regulated genes and genes necessary for polymyxin resistance" .
May 2001 Gunn JS, McCoy AJ, Tran L, Liu H, Falla T."Identification and characterization of Burkholderia cepacia mutants sensitive to antimicrobial peptides" .
March 2001 Gunn JS, McCoy AJ, Ryan SS."The role of LPS modification in bacterial virulence and resistance to antimicrobial peptides" .
May 2001 Prouty AM, Gunn JS."The formation of biofilms on gallstones by Salmonella spp" .
May 2001 Carroll A, Gunn JS."Identification and characterization of a novel two-component regulatory system in Salmonella typhimurium" .
May 2001 Prouty AM, Gunn JS."The formation of biofilms on gallstones by Salmonella spp" .
January 2001 A. Carroll and J.S. Gunn."Identification and characterization of a novel two-component regulatory system in Salmonella typhimurium" .
March 2001 Gunn JS, McCoy AJ, Ryan SS."The role of LPS modification in bacterial virulence and resistance to antimicrobial peptides" .
May 2001 Carroll A, Gunn JS."Identification and characterization of a novel two-component regulatory system in Salmonella typhimurium" .
January 2001 Vivanco Cid H, Maldonado Bernal C, Pastelin Palacios R, Gunn JS, Alpuche Aranda C, Isibasi A, Lopez Macias C."Efecto de las modificaciones estructurales del lipido a del lipopolisacarido de Salmonella typhimurium en la induccion de la respuesta inmune innata" .
May 2001 Tamayo R, Ryan SS, McCoy AJ, Gunn JS."Identification and characterization of Salmonella typhimurium PmrA-PmrB regulated genes and genes necessary for polymyxin resistance" .
May 2001 Tamayo R, Ryan SS, McCoy AJ, Gunn JS."Identification and chracterization of Salmonella typhimurium PmrA-PmrB regulated genes and genes necessary for polymyxin resistance" .
January 2001 Vivanco Cid Héctor, Maldonado Bernal Ma. Del Carmen, Pastelin Palacios Rodolfo, John S. Gunn, Alpuche Aranda Celia, Isibasi Armando, y López Macías Constantino."Efecto de las modificaciones estructurales del lipido a del lipopolisacarido de Salmonella typhimurium en la inducción de la respuesta inmune innata" .
January 2002 Tamayo R, Prouty AM, Gunn JS."Identification of Salmonella enterica serovar Typhimurium PmrA-regulated genes using DNA microarray analysis" .
January 2002 Prouty AM, Gunn JS."Bile resistance/response and gallstone biofilms in typhoid carriers" .
January 2002 Prouty AM, Gunn JS."Bile resistance/response and gallstone biofilms in typhoid carriers" .
January 2002 Vallor AC, Gunn JS, Klose KE."Construction of recombinant DNA plasmids carrying and expressing protective antigen (PA) from Bacillus anthracis and Tul4 and FopA from Francisella tularensis" .
January 2002 Vallor AC, Gunn JS, Klose KE."Construction of recombinant DNA plasmids carrying and expressing protective antigen (PA) from Bacillus anthracis and Tul4 and FopA from Francisella tularensis" .
January 2002 Tamayo R, Prouty AM, Gunn JS."Identification of Salmonella enterica serovar Typhimurium PmrA-regulated genes using DNA microarray analaysis" .
March 2003 Prouty AM, Gunn JS."Novel bile salt-mediated induction of antimicrobial resistance in Salmonella typhimurium" .
September 2003 Devine DA, Walling S, Morgan MM, Ashcroft AE, Bonass WA, Keen JN, Percival RS, Yousuf Z, Gunn JS."Interactions Between Antimicrobial Peptides and Polymyxin B Sensitive Burkholderia cepacia Mutants in Relation to Lipopolysaccharide Structure" .
September 2003 Carroll-Portillo A, Prouty A, Manos J, Belas R, Gunn JS."The role of UblAB in S. enterica serovar Typhimurium motility and type III secretion" .
May 2003 Mammarappallil JG, Prouty AM, Gunn JS."Characterization of the Salmonella typhimurium outer membrane virulence factor PagC" .
September 2003 Carroll-Portillo A, Prouty A, Manos J, Belas R, Gunn J."The role of UblAB in S. enterica serovar Typhimurium motility and type III secretion" .
May 2003 Portillo AC, Gunn JS."Analysis of virulence phenotypes associated with the Salmonella typhimurium UblAB two-component regulatory system" .
September 2003 Tamayo R, Tran LT, Gunn J."PmrA-mediated LPS modifications- Role in survival of S. enterica serovar Typhimurium" .
May 2003 Portillo AC, Gunn JS."Analysis of virulence phenotypes associated with the Salmonella typhimurium UblAB two-component regulatory system" .
September 2003 Tamayo R, Tran LT, Gunn JS."PmrA-mediated LPS modifications-Role in survival of S. enterica serovar Typhimurium in the mouse small intestine" .
September 2003 Devine DA, Walling S, Morgan MM, Ashcroft AE, Bonass WA, Keen JN, Percival RS, Yousuf Z, Gunn J."Interactions Between Antimicrobial Peptides and Polymyxin B Sensitive Burkholderia cepacia Mutants in Relation to Lipopolysaccharide Structure" .
March 2003 Prouty AM, Gunn JS."Novel bile salt-mediated induction of antimicrobial resistance in Salmonella typhimurium" .
May 2003 Mammarappallil JG, Prouty AM, Gunn JS."Characterization of the Salmonella typhimurium outer membrane virulence factor PagC" .
August 2004 Maier RJ, Olczak A, Maier S, Soni S, Gunn JS."Role of Hydrogen Use in Pathogenesis by Infectious Bacteria" .
May 2004 Navarre W, Halsey T, Frye J, Walthers D, McClelland M, Potter J, Kenney L, Gunn JS, Fang F, Libby SJ."Apparent Regulation of SlyA Specificity by PhoP in Salmonella enterica" .
March 2004 Vallor AC, Lauriano CM, Patterson JL, Gunn JS, Klose KE."Evaluation of Attenuated Salmonella Typhimurium Vaccines Expressing Bacillus Anthracis Protective Antigen In Mice" .
October 2004 Merighi M, Ellermeier CD, Slauch JM, Gunn JS."Recombination-based in vivo expression technology analysis shows extracellular expression of the Salmonella enterica sv. Typhimurium pmrHFIJKLM locus in the illeal lumen of BALB/c mice" .
May 2004 Soni S, Klose KE, Gunn JS."Construction of a Novel Live-Attenuated Vaccine for Food-Borne Pathogens" .
October 2004 Mohapatra N, Soni S, Perry MB, Vinogradov E, Gunn JS."Genetic and Structural Analysis if Francisella spp. LPS" .
March 2004 Gunn JS, Soni S, Crawford RW, Nano FE, Perry MB,Vinogradov E, Conlan WJ."Franciaella tularensis LPS Phase Variation: Role in Virulence and Innate Immune Killing" .
March 2004 Gunn JS, Soni S, Crawford RW, Nano FE, Perry MB, Vinogradov E, Conlan WJ."Francisella tularensis LPS Phase Variation: Role in Virulence and Innate Immune Killing" .
January 2004 Maier RJ, Olczak A, Maier S, Soni S, Gunn J."Role of hydrogen use in pathogenesis by infectious bacteria" .
March 2004 Vallor AC, Lauriano CM, Patterson JL, Gunn JS, Klose KE."Evaluation of Attenuated Salmonella Typhimurium Vaccines Expressing Bacillus Anthracis Protective Antigen In Mice" .
May 2004 Soni S, Klose KE, Gunn JS."Construction of a Novel Live-Attenuated Vaccine for Food-Borne Pathogens" .
May 2004 Navarre W, Halsey T, Frye J, Walthers D, McClelland M, Potter J, Kenney L, Gunn J, Fang F , Libby SJ."Apparent Regulation of SlyA Specificity by PhoP in Salmonella enterica" .
October 2004 Mohapatra N, Soni S, Perry MB, Vinogradov E, Gunn JS."Genetic and Structural Analysis if Francisella spp. LPS" .
October 2004 Merighi M, Ellermeier CD, Slauch JM, Gunn JS."Recombination-based in vivo expression technology analysis shows extracellular expression of the Salmonella enterica sv. Typhimurium pmrHFIJKLM locus in the illeal lumen of BALB/c mice" .
March 2005 Balagopal A, Shearer Macfarlane A, Mohapatra N, Soni S, Gunn JS, Schlesinger LS."Identification of receptor-ligand interactions that mediate entry of Francisella novicida and the Live Vaccine Strain of Francisella tularensis into human macrophages" .
November 2005 Soni S, Mohapatra N, Perry M, Vinogradov E, Muszynski A, Choudhury B, Carlson R, Balagopal A, Schlesinger LS, Gunn JS."Francisella tularensis LPS phase variation is not due to major structural alterations but affects intramacrophage survival" .
October 2005 Crawford RW, Gunn JS."Salmonella bile sensing and bile-mediated biofilm formation" .
October 2005 Bhatiya A, Gunn JS."Identification of PmrA-PmrB constitutive mutations in Salmonella enterica serovar Typhimurium" .
October 2005 Crawford RW, Gunn JS."Salmonella bile sensing and bile-mediated biofilm formation" .
November 2005 Mohapatra N, Soni S, Balagopal A, Schlesinger LS, Gunn JS."AcpA, an Acid Phosphatase involved in FrancisellaVirulence" .
October 2005 Bhatiya A, Gunn JS."Identification of PmrA-PmrB constitutive mutations in Salmonella enterica serovar Typhimurium" .
November 2005 Soni S, Mohapatra N, Perry M,Vinogradov E , Muszynski A, Choudhury B, Carlson R, Balagopal A, Schlesinger LS, Gunn JS."Francisella tularensis LPS phase variation is not due to major structural alterations but affects intramacrophage survival" .
October 2005 Crawford RW, Gunn JS."Salmonella bile sensing and bile-mediated biofilm formation" .
March 2005 Devine DA, Morgan MM, Ashcroft AE, Keen J, Gunn JS, Percival RS, Bonass WA, Yousuf Z, Marsh PD."Environmental regulation in Burkholderia cenocepacia of cell components relevant to interactions with host defence peptides" .
October 2005 Soni S, Mohapatra N, Perry M, Vinogradov E, Muszynski A, Carlson R, Balagopal A, Schlesinger LS, Gunn JS."The interplay between Francisella tularensis LPS phase variation and innate immunity" .
October 2005 Mohapatra N, Soni S, Balagopal A, Schlesinger LS, Gunn JS."The role of the acid phosphatase AcpA in virulence and intramacrophage survival of Francisella novicida" .
November 2005 Mohapatra N, Soni S, Balagopal A, Schlesinger LS, Gunn JS."AcpA, an Acid Phosphatase involved in Francisella Virulence" .
October 2005 Merighi M, Carroll-Portillo A, Septer AN, Bhatiya A, Gunn JS."The Role of PreA/PreB two-component system in modulating PmrA-regulated gene transcription in Salmonella enterica serovar Typhimurium" .
October 2005 Soni S, Mohapatra N, Perry M, Vinogradov E, Muszynski A, Carlson R, Balagopal A, Schlesinger LS, Gunn JS."The interplay between Francisella tularensis LPS phase variation and innate immunity" .
October 2005 Mohapatra N, Soni S, Balagopal A, Schlesinger LS, Gunn JS."The role of the acid phosphatase AcpA in virulence and intramacrophage survival of Francisella novicida" .
October 2005 Merighi M, Carroll-Portillo A, Septer AN, Bhatiya A, Gunn JS."The Role of PreA/PreB two-component system in modulating PmrA-regulated gene transcription in Salmonella enterica serovar Typhimurium" .
March 2005 Devine DA, Morgan MM, Ashcroft AE, Keen J, Gunn JS, Percival RS, Bonass WA, Yousuf Z, Marsh PD."Environmental regulation in Burkholderia cenocepacia of cell components relevant to interactions with host defence peptides" .
March 2005 Balagopal A, Macfarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS."Identification of receptor-ligand interactions that mediate entry of Francisella novicida and the Live Vaccine Strain of Francisella tularensis into human macrophages" .
November 2006 Soni S, Bell BL, Warren R, Mohapatra NP, Clay CD, Ernst RK, Schlesinger LS, Gunn JS."Phenotypic and Genetic Changes in the Blue to Gray Phase Variation of Francisella tularensis" .
November 2006 Clay CD, Gunn JS, Schlesinger LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
January 2006 A. Balagopal, A.S. MacFarlane, N. Mohapatra, S. Soni, J.S. Gunn, L.S. Schlesinger."Characterization of the receptor-ligand pathways important for entry and survival of Francisella novicida and the Live Vaccine Strain (LVS) of F. tularensis in human macrophages" .
September 2006 Gavrilin MA, Bouakl I, Knatz NL, Duncan M, Hall M, Gunn JS, Wewers MD."Internalization and Phagosome Escape Required for Francisella to Induce Human Monocyte IL-1 Processing and Release" .
October 2006 Crawford RW, Gunn JS."Salmonella bile sensing and bile-mediated biofilm formation" .
November 2006 Nasr AB, Haithcoat J, Masterson JP,Gunn JS, Eaves-Pyles T,Klimpel GR."Critical Role for Serum Opsonins and Complement Receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by Human Dendritic Cells (DC): Uptake of Francisella Leads to Activation of Immature DCs and Intracellular Survival of the Bacteria" .
November 2006 Clay CD, Gunn JS, Schlesinger LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
November 2006 Vangelakos G, Raulie EK, Juen J, Gunn JS, Chambers JP, Guentzel MN, Arulanandam BP."Proteases Produced by Francisella tularensis Inhibit the Activity of Alkaline Phosphatase in a Murine Model" .
January 2006 Clay, CD, Gunn, JS, Schlesinger, LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
September 2006 Rajaram MVS, Ganesan LP, Parsa KVL, Butchar JP, Gunn JS, Tridandapani S."Protein Kinase B/Akt Modulates Macrophage Inflammatory Response to Francisella tularensis Infection and Confers a Survival Advantage in Mice" .
November 2006 C.D. Clay, J.S. Gunn, and L.S. Schlesinger."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains”." .
November 2006 C.D. Clay, J.S. Gunn, and L.S. Schlesinger."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
January 2006 Clay, CD, Gunn, JS, Schlesinger, LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
November 2006 Mohapatra NP, Soni S, Reilly TJ, Liu J, Klose KE, Gunn JS."Construction and characterization of a F. novicida strain containing multiple acid phosphatase gene deletions" .
November 2006 Mohapatra NP, Soni S, Reilly TJ, Liu J, Klose KE, Gunn JS."Construction and characterization of a F. novicida strain containing multiple acid phosphatase gene deletions" .
March 2006 Clay CD,Gunn JS, Schlesinger LS."Francisella tularensis activates the complement system in human serum, but is resistant to complement-mediated lysis" .
November 2006 N.P. Mohapatra, S. Soni, T.J. Reilly, J. Liu, K.E. Klose and J.S. Gunn."Construction and characterization of a F. novicida strain containing multiple acid phosphatase gene deletions" .
November 2006 M.V.S. Rajaram, L.P. Ganesan, K.V.L. Parsa, J.P. Butcher, J.S. Gunn, and S. Tridandapani."Protein kinase B/Akt modulates macrophage inflammatory response to Francisella tularensis infection and confers a survival advantage in mice" .
November 2006 Vangelakos G, Raulie EK, Jieh-Juen, Gunn JS, Chambers JP, Guentzel MN, Arulanandam BP."Proteases Produced by Francisella tularensis Inhibit the Activity of Alkaline Phosphatase in a Murine Model" .
September 2006 Crawford RC, Gunn JS."Salmonella Bile Sensing and Bile-Mediated Biofilm Formation" .
September 2006 Rajaram MVS, Ganesan LP, Parsa KVL, Butchar JP, Gunn JS and Tridandapani S."Protein Kinase B /Akt Modulates Macrophage Inflammatory Response to Fransicella tularensis Infection and Confers a Survival Advantage in Mice" .
February 2006 Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS."Characterization of the receptor-ligand pathways important for entry and survival of Francisella novicida and the Live Vaccine Strain (LVS) of F. tularensis in human macrophages" .
March 2006 Clay CD, Gunn JS, Schlesinger LS."Francisella tularensis activates the complement system in human serum, but is resistant to complement-mediated lysis" .
September 2006 Crawford RC, Gunn JS."Salmonella Bile Sensing and Bile-Mediated Biofilm Formation" .
January 2006 Clay CD, Gunn JS, Schlesinger LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
November 2006 Mohapatra NP, Soni S, Reilly TJ, Liu J, Klose KE, Gunn JS."Construction and characterization of a F. novicida strain containing multiple acid phosphatase gene deletions" .
November 2006 Mohapatra NP, Soni S, Reilly TJ, Liu J, Klose KE, Gunn JS."Construction and characterization of a F. novicida strain containing multiple acid phosphatase gene deletions" .
November 2006 Clay CD, Gunn JS, Schlesinger LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
September 2006 Parsa KVL, Ganesan LP, Rajaram MVS, Gavrilin MA, Balagopal A, Mohapatra NP, Wewers MD, Schlesinger LS, Gunn JS and Tridandapani S."Macrophage Pro-inflammatory Response to Francisella novicida Infection is Regulated by the SH2 Domain-containing Inositol 5’ Phosphatase SHIP" .
September 2006 Gavrilin MA , Bouakl I, Knatz NL, Duncan M, Hall M, Gunn JS, Wewers MD."Internalization and Phagosome Escape Required for Francisella to Induce Human Monocyte IL-1? Processing and Release" .
November 2006 Soni S, Bell BL, Warren R, Mohapatra NP, Clay CD, Ernst RK, Schlesinger LS, Gunn JS."Phenotypic and Genetic Changes in the Blue to Gray Phase Variation of Francisella tularensis" .
November 2006 Rajaram MVS, Ganesan LP, Parsa KVL, Butcher JP, Gunn JS, Tidandapani S."Protein kinase B/Akt modulates macrophage inflammatory response to Francisella tularensis infection and confers a survival advantage in mice" .
November 2006 A. Ben Nasr, J. Haithcoat, J.P. Masterson, J.S. Gunn, T. Eaves-Pyles, and G.R. Klimpel."Critical Role for Serum Opsonins and Complement Receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by Human Dendritic Cells (DC): Uptake of Francisella Leads to Activation of Immature DCs and Intracellular Survival of the Bacteria" .
September 2006 Parsa KVL, Ganesan LP, Rajaram MVS, Gavrilin MA, Balagopal A, Mohapatra NP, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S."Macrophage Pro-inflammatory Response to Francisella novicida Infection is Regulated by the SH2 Domain-containing Inositol 5' Phosphatase SHIP" .
November 2006 Ben Nasr A, Haithcoat J, Masterson JP, Gunn JS, Eaves-Pyles T, Klimpel GR."Critical Role for Serum Opsonins and Complement Receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by Human Dendritic Cells (DC): Uptake of Francisella Leads to Activation of Immature DCs and Intracellular Survival of the Bacteria" .
November 2006 Rajaram MVS, Ganesan LP, Parsa KVL, Butcher JP, Gunn JS, Tridandapani S."Protein kinase B/Akt modulates macrophage inflammatory response to Francisella tularensis infection and confers survival advantage in mice" .
June 2007 S. Soni, N. Mohapatra, M. Perry, E. Vinogradov , R.K. Ernst, C. Clay, B.L. Bell, L. S. Schlesinger , and J.S. Gunn."Francisella tularensis LPS phase variation and its role in innate immunity" .
June 2007 Mohapatra NP, Soni S, Liu J, Klose KE, Gunn JS."Multiple deletions of acid phosphatases in Francisella novicida affect virulence, intramacrophage survival and trafficking" .
September 2007 Richards SM, Gunn JS."Environmental sensing by Salmonella two-component regulatory systems" .
September 2007 Clay CD, Gunn JS, Schlesinger LS."Complement activation and component deposition on Francisella tularensis" .
June 2007 S. Richards and J.S. Gunn."Intestinal Innate Immunity and Salmonella Virulence" .
September 2007 Crawford RW, Gunn JS."A bile-induced exopolysaccharide required for Salmonella biofilm formation" .
November 2007 Bell BL, Mohapatra NP, Warren R, Gunn JS."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
June 2007 Bell BL, Mohapatra NP, Warren R, Gunn JS."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
September 2007 S.M. Richards and J.S. Gunn."Environmental sensing by Salmonella two-component regulatory systems”" .
September 2007 R.W. Crawford and J.S. Gunn."A bile-induced exopolysaccharide required for Salmonella biofilm formation" .
November 2007 B.L. Bell, N.P. Mohapatra, R. Warren and J.S. Gunn."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
March 2007 S. Richards and J.S. Gunn."Intestinal Innate Immunity and Salmonella Virulence" .
June 2007 N.P. Mohapatra, S. Soni, J. Liu, K.E. Klose, J.S. Gunn.."Multiple deletions of acid phosphatases in Francisella novicida affect virulence, intramacrophage survival and trafficking" .
June 2007 B.L. Bell, N.P. Mohapatra, R. Warren and J.S. Gunn."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
March 2007 C.D. Clay, J.S. Gunn, and L.S. Schlesinger."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
March 2007 B.L. Bell, N.P. Mohapatra, R. Warren and J.S. Gunn."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
September 2007 C.D. Clay, J.S. Gunn, L.S. Schlesinger."Complement activation and component deposition on Francisella tularensis" .
June 2007 Clay CD, Gunn JS, Schlesinger LS."Intestinal Innate Immunity and Salmonella Virulence" .
March 2007 Richards S, Gunn JS."Intestinal Innate Immunity and Salmonella Virulence" .
March 2007 Bell BL, Mohapatra NP, Warren R, Gunn JS."An Orphan Response Regulator that is Necessary for Francisella Virulence and Transcription of Pathogenicity Genes" .
June 2007 Soni S, Mohapatra N, Perry M, Vinogradov E, Ernst RK, Clay C, Bell BL, Schlesinger LS, Gunn JS."Francisella tularensis LPS phase variation and its role in innate immunity" .
March 2007 Clay CD, Gunn JS, Schlesinger LS."Differential complement activation and C3 component deposition on various Francisella tularensis subspecies and strains" .
September 2008 Bullard B, Gonzalez G, Crawford RW, Gunn JS."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
September 2008 Richards SM, Conroy M, Fierer J, Gunn JS."The role of antimicrobial peptides and the microflora in the oral virulence defect of Salmonella aminoarabinose-deficient mutants" .
September 2008 Bullard B, Gonzalez G, Crawford RW, Gunn JS."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
March 2008 Bell BL, Mohapatra NP, Gunn JS."A Francisella Orphan Response Regulator Required for Transcription of Pathogenicity Genes and Virulence" .
March 2008 B.L. Bell, N. P. Mohapatra and J. S. Gunn."A Francisella Orphan Response Regulator Required for Transcription of Pathogenicity Genes and Virulence" .
September 2008 S.M. Richards, M. Conroy, J. Fierer and J.S. Gunn.."The role of antimicrobial peptides and the microflora in the oral virulence defect of Salmonella aminoarabinose-deficient mutants" .
September 2008 S.M. Richards, M. Conroy, J. Fierer and J.S. Gunn."The role of antimicrobial peptides and the microflora in the oral virulence defect of Salmonella aminoarabinose-deficient mutants" .
April 2008 S.M. Richards, M. Conroy and J.S. Gunn."PhoPQ- and PmrAB-mediated environmental sensing and lipid A modifications are involved in Salmonella virulence" .
September 2008 C.D. Clay, S. Soni, J.S. Gunn, and L.S. Schlesinger."LPS O-antigen dictates whether complement activation by Francisella tularensis results in microbial lysis by regulating C3 deposition"." .
September 2008 B.L. Bell, N. P. Mohapatra and J. S. Gunn."PmrA is a Francisella Orphan Response Regulator that Binds Regulated Promoters and Activates Virulence Factor Expression" .
September 2008 B. Bullard, G. Gonzalez, R.W. Crawford and J.S. Gunn."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
September 2008 B. Bullard, G. Gonzalez, R.W. Crawford and J.S. Gunn."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
April 2008 Richards SM, Conroy M, Gunn JS."PhoPQ- and PmrAB-mediated environmental sensing and lipid A modifications are involved in Salmonella virulence" .
April 2008 Conroy M, Richards SM, Gunn JS."The role of two component regulatory systems and LPS modifications in Salmonella enterica resistance to antimicrobial peptides" .
April 2008 Clay CD, Soni S, Gunn JS, Schlesinger LS."Evasion of complement-mediated lysis by Francisella tularensis" .
September 2008 Richards SM, Conroy M, Fierer J, Gunn JS."The role of antimicrobial peptides and the microflora in the oral virulence defect of Salmonella aminoarabinose-deficient mutants" .
September 2008 Clay CD, Soni S, Gunn JS, Schlesinger LS."LPS O-antigen dictates whether complement activation by Francisella tularensis results in microbial lysis by regulating C3 deposition" .
September 2008 Bell BL, Mohapatra NP, Gunn JS."PmrA is a Francisella Orphan Response Regulator that Binds Regulated Promoters and Activates Virulence Factor Expression" .
April 2008 C.D. Clay, S. Soni, J.S. Gunn, and L.S. Schlesinger."Evasion of complement-mediated lysis by Francisella tularensis" .
April 2008 M. Conroy, S.M. Richards and J.S. Gunn."The role of two component regulatory systems and LPS modifications in Salmonella enterica resistance to antimicrobial peptides.”" .
October 2009 Crawford RW, Reeve KE, Gunn JS."Salmonella Flagella Mediate Binding to Cholesterol during Biofilm Formation" .
May 2009 Crawford RW, Reeve KE, Gunn JS."Salmonella Flagella Mediate Binding to Cholesterol during Biofilm Formation" .
March 2009 Richards SM, Conroy M, Fierer J, Colgan SP, Canny GO, Gunn JS."The role of antimicrobial peptides and the microflora in host selection against Salmonella strains deficient in LPS modification" .
April 2009 Bullard B, Gonzalez G, Crawford RW, Gunn JS."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
April 2009 Crawford RW, Reeve KE, Gunn JS."Flagellar filament mediates Salmonella binding to and biofilm initiation on cholesterol" .
October 2009 Gonzalez-Escobedo G, Bullard B, Crawford RW, Gunn JS."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
April 2009 Clay CD, Soni S, Gunn JS, Schlesinger LS."LPS O-antigen dictates whether complement activation by Francisella tularensis results in microbial lysis by regulating C3 deposition" .
October 2009 G. Gonzalez-Escobedo, B. Bullard, R.W. Crawford and J. S. Gunn."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
April 2009 R.W. Crawford, K.E. Reeve, and J.S. Gunn."Flagellar filament mediates Salmonella binding to and biofilm initiation on cholesterol" .
April 2009 C.D. Clay, S. Soni, J.S. Gunn, and L.S. Schlesinger.."LPS O-antigen dictates whether complement activation by Francisella tularensis results in microbial lysis by regulating C3 deposition" .
April 2009 B.L. Bell, N. P. Mohapatra and J. S. Gunn."A Francisella Orphan Response Regulator Required for Transcription of Pathogenicity Genes and Virulence" .
April 2009 B. Bullard, G. Gonzalez, R.W. Crawford and J.S. Gunn."Bile Induced Repression of the Salmonella Typhimurium SPI-1 Type Three Secretion System" .
October 2009 R.W. Crawford, K.E. Reeve, and J.S. Gunn."Salmonella Flagella Mediate Binding to Cholesterol during Biofilm Formation" .
April 2009 Bell BL, Mohapatra NP, Gunn JS."A Francisella Orphan Response Regulator Required for Transcription of Pathogenicity Genes and Virulence" .
September 2009 Kim B, Richards SM, Gunn JS, Slauch JM."The Role of Periplasmic Cu/Zn Superoxide Dismutases of Salmonella Typhimurium in Protection Against Phagocytic Superoxide" .
April 2009 Richards SM, Conroy M, Fierer J, Colgan SP, Canny GO, Gunn JS."The role of antimicrobial peptides and the microflora in host selection against Salmonella strains deficient in LPS modification" .
October 2009 Richards SM, Gunn JS."The role of antimicrobial peptides in host selection against Salmonella strains deficient in LPS modification" .
April 2009 S.M. Richards, M. Conroy, J. Fierer, S.P. Colgan, G.O. Canny and J.S. Gunn."The role of antimicrobial peptides and the microflora in host selection against Salmonella strains deficient in LPS modification" .
September 2009 B. Kim, S. M. Richards, J. S. Gunn and J. M. Slauch."The Role Of Periplasmic Cu/Zn Superoxide Dismutases Of Salmonella Typhimurium In Protection Against Phagocytic Superoxide" .
October 2009 S.M. Richards and J.S. Gunn."The role of antimicrobial peptides in host selection against Salmonella strains deficient in LPS modification" .
May 2009 R.W. Crawford, K.E. Reeve, and J.S. Gunn.."Salmonella Flagella Mediate Binding to Cholesterol during Biofilm Formation" .
May 2010 Jarjour NN, Strandberg KL, Gunn JS."Modulation of innate immunity by Salmonella lipopolysaccharide modification" .
March 2010 Strandberg KL, Richards SM, Chen C, Besner GM, Gunn JS."In vivo PhoP/PhoQ-and PmrA/PmrB-Induced Lipopolysaccharide Modifications Alter Innate Immune Responses in the Mouse Intestine" .
January 2010 C.L. Chen, A. Radulescu, I. A.-O. James, H.Y. Zhang, J. S. Gunn and G. E. Besner."HB-EGF Promotes α-defensin Secretion from Intestinal Paneth Cells”" .
October 2010 Jarjour NN, Strandberg KL, Gunn JS."Modulation of the innate immune response by Salmonella lipopolysaccharide modification" .
March 2010 Soni S, Mohapatra NP, Gunn JS."Environmental modulation and intraspecies variation of the PmrA-KdpD two-component Regulatory system of Francisella tularensis" .
October 2010 Strandberg KL, Richards SM, Gunn JS."Effects of PhoP/PhoQ- and PmrA/PmrB-Induced Lipopolysaccharide Modifications on Innate Immune Responses in the Mouse Intestine" .
May 2010 Reeve KE, Crawford RW, Gunn JS."Salmonella Genes Required for Biofilm Formation on Cholesterol Surfaces" .
March 2010 Richards SM, Conroy ME, Strandberg K, Gunn JS."S. Typhi and S. Typhimurium Exhibit Variations in PhoPQ-and PmrAB-regulated LPS Modifications and Antimicrobial Peptide Resistance" .
March 2010 K. E. Reeve, R. W. Crawford, and J. S. Gunn."Identification of Salmonella enterica serovar Typhimurium genes required for biofilm formation on cholesterol-coated surfaces" .
March 2010 K. L. Strandberg, S. M. Richards, C. Chen, G. M. Besner, and J. S. Gunn."In vivo PhoP/PhoQ- and PmrA/PmrB-Induced Lipopolysaccharide Modifications Alter Innate Immune Responses in the Mouse Intestine”," .
March 2010 G. Gonzalez-Escobedo and J. S. Gunn."Biofilm and cholesterol mediated transcriptional responses in Salmonella spp.”," .
May 2010 N. N. Jarjour, K. L. Strandberg, and J. S. Gunn."Modulation of innate immunity by Salmonella lipopolysaccharide modification"," .
May 2010 K. E. Reeve, R. W. Crawford, and J. S. Gunn."Salmonella Genes Required for Biofilm Formation on Cholesterol Surfaces" .
October 2010 K.L. Strandberg, S.M. Richards, J.S. Gunn."Effects of PhoP/PhoQ- and PmrA/PmrB-induced lipopolysaccharide modifications on Innate Immune responses in the mouse intestine" .
October 2010 Kristi L. Strandberg, Susan M. Richards, and John S. Gunn."Effects Of PhoP/PhoQ- And PmrA/PmrB-Induced Lipopolysaccharide Modifications On Innate Immune Responses In The Mouse Intestine" .
March 2010 S. Soni, N. P. Mohapatra and J. S. Gunn."Environmental modulation and intraspecies variation of the PmrA-KdpD two-component Regulatory system of Francisella tularensis" .
March 2010 S. M. Richards, M. E. Conroy, K. Strandberg and J. S. Gunn."S. Typhi and S. Typhimurium Exhibit Variations in PhoPQ- and PmrAB-regulated LPS Modifications and Antimicrobial Peptide Resistance" .
October 2010 N. N. Jarjour, K. L. Strandberg and J. S. Gunn."Modulation of the innate immune response by Salmonella lipopolysaccharide modification" .
April 2010 G. Gonzalez-Escobedo and J. S. Gunn."Biofilm and cholesterol mediated transcriptional responses in Salmonella spp" .
September 2010 S. M. Richards, M. E. Conroy, K. Strandberg and J. S. Gunn."S. Typhi and S. Typhimurium LPS modification mutants exhibit increased sensitivity to antimicrobial peptides and reduced intracellular survival" .
March 2010 Gonzalez-Escobedo G, Gunn JS."Biofilm and cholesterol mediated transcriptional responses in Salmonella spp" .
April 2010 Strandberg KL, Richards SM, Chen C, Besner GM, Gunn JS."Effects of PhoP/PhoQ- and PmrA/PmrB-Induced Lipopolysaccharide Modifications on Innate Immune Responses in the Mouse Intestine" .
April 2010 Richards SM, Conroy ME, Strandberg K, Gunn JS."S. Typhi and S. Typhimurium Exhibit Variations in PhoPQ- and PmrAB-regulated LPS Modifications and Antimicrobial Peptide Resistance" .
September 2010 Richards SM, Conroy ME, Strandberg K, Gunn JS."S. Typhi and S. Typhimurium LPS modification mutants exhibit increased sensitivity to antimicrobial peptides and reduced intracellular survival" .
October 2010 Strandberg KL, Richards SM, Gunn JS."Effects of PhoP/PhoQ- and PmrA/PmrB-induced lipopolysaccharide modifications on Innate Immune responses in the mouse intestine" .
April 2010 Gonzalez-Escobedo G, Gunn JS."Biofilm and cholesterol mediated transcriptional responses in Salmonella spp" .
April 2010 S. M. Richards, M. E. Conroy, K. Strandberg and J. S. Gunn."S. Typhi and S. Typhimurium Exhibit Variations in PhoPQ- and PmrAB-regulated LPS Modifications and Antimicrobial Peptide Resistance" .
April 2010 K. L. Strandberg, S. M. Richards, C. Chen, G. M. Besner, and J. S. Gunn."Effects of PhoP/PhoQ- and PmrA/PmrB-Induced Lipopolysaccharide Modifications on Innate Immune Responses in the Mouse Intestine" .
March 2010 Reeve KE, Crawford RW, Gunn JS."Identification of Salmonella enterica serovar Typhimurium genes required for biofilm formation on cholesterol-coated surfaces" .
June 2011 Gonzalez-Escobedo G, Gunn JS."Biofilm genes specifically regulated on gallstone (cholesterol) surfaces" .
August 2011 Shah P, Gavrilin M, Cremer T, Butchar J, Zahrt T, Mohapatra N, Curry H, Gunn JS, Schlesinger LS, Wewers MD, Tridandapani S."Virulent Francisella actively suppress host immune response" .
October 2011 Jarjour NN, Strandberg KL, Gunn JS."Modulation of innate immunity by Salmonella lipopolysaccharide modification" .
July 2011 Strandberg KL, Gunn JS."Effects of Salmonella PhoP-PhoQ- and PmrA-PmrB- mediated lipopolysaccharide modifications on LL-37 expression in human monocyte-derived macrophages" .
December 2011 Strandberg KL, Gunn JS."The Antimicrobial Peptide LL-37 is not Induced in Human Monocyte-derived Macrophages by Infection with Salmonella enterica serovar Typhi or Exposure to Purified Lipopolysaccharide" .
April 2011 Gonzalez-Escobedo G, Gunn JS."Salmonella spp. mechanisms for persistence in the gallbladder during chronic typhoid carriage" .
March 2011 S.M. Richards, M. Conroy, J. Fierer, S.P. Colgan, G.O. Canny and J.S. Gunn."The role of antimicrobial peptides and the microflora in host selection against Salmonella strains deficient in LPS modification" .
September 2011 Strandberg KL, Gunn JS."Effects of Salmonella PhoP-PhoQ- and PmrA-PmrB-mediated lipopolysaccharide modifications on LL-37 expression in human monocyte-derived macrophages" .
October 2011 Strandberg KL, Gunn JS."Effects of Salmonella PhoP-PhoQ-and PmrA-PmrB-mediated lipopolysaccharide modifications on LL-37 expression in human monocyte-derived macrophages" .
March 2011 N. P. Mohapatra, A. Harrison, S. Soni and J. S. Gunn."Regulation of Francisella tularensis virulence factors by small non-coding RNAs" .
June 2011 G. Gonzalez-Escobedo and J.S. Gunn."Biofilm genes specifically regulated on gallstone (cholesterol) surfaces" .
April 2011 S. Dai, H.M. Curry, J.S. Gunn and L. S. Schlesinger."A link between complement receptor 3-mediated uptake of Francisells tularensis and immune suppression in human macrophages" .
April 2011 Dai S, Curry HM, Gunn JS, Schlesinger LS."A link between complement receptor 3-mediated uptake of Francisella tularensis and immune suppression in human macrophages" .
March 2011 Mohapatra NP, Harrison A, Soni S, Gunn JS."Regulation of Francisella tularensis virulence factors by small non-coding RNAs" .
April 2011 Strandberg KL, Richards SM, Gunn JS."Effects of PhoP/PhoQ- and PmrA/PmrB-Induced Lipopolysaccharide Modifications on Innate Immune Responses In the Mouse Intestine" .
April 2011 Kristi L. Strandberg, Susan M. Richards, and John S. Gunn.."Effects Of PhoP/PhoQ- And PmrA/PmrB-Induced Lipopolysaccharide Modifications On Innate Immune Responses In The Mouse Intestine" .
August 2011 Jarjour NN, Strandberg KL, Gunn JS."Modulation of innate immunity by Salmonella lipopolysaccharide modification" .
August 2011 Jarjour NN, Strandberg KL, Gunn JS."Modulation of innate immunity by Salmonella lipopolysaccharide modification" .
July 2011 Kristi L. Strandberg and John S. Gunn."Effects of Salmonella PhoP-PhoQ- and PmrA-PmrB-mediated lipopolysaccharide modifications on LL-37 expression in human monocyte-derived macrophages" .
April 2011 G. Gonzalez-Escobedo and J.S. Gunn."Salmonella spp. mechanisms for persistence in the gallbladder during chronic typhoid carriage" .
April 2012 Strandberg KL, Gunn JS."The antimicrobial peptide LL-37 is not induced or required for bacterial clearance during Salmonella enterica infection of human monocyte-derived macrophages" .
April 2012 Gonzalez-Escobedo G, Gunn JS."Transcriptomics and proteomics unveil inhibitors of Salmonella biofilms on cholesterol gallstones" .
March 2012 Clay CD, Dai S, Gunn JS, Schlesinger LS."Antibody-independent binding and activation of complement component C1 by wildtype and LPS O-antigen deficient Francisella tularensis" .
April 2012 Reeve KE, Marshall JM, Abley MJ, Gebreyes WA, Gunn JS."Comparative analysis of Salmonella enterica serovar Typhi isolates from acute and chronic infections" .
April 2012 Gonzalez-Escobedo G, Gunn JS."The gallbladder epithelium as a niche in chronic typhoid chronic carriage" .
June 2012 Gonzalez-Escobedo G, Gunn JS."Role of the gallbladder epithelium in chronic typhoid carriage" .
May 2012 Koopman J, Bhatiya A, Eguale T, Drew M, Gunn JS."Development of a kinase-targeting high throughput screen for Salmonella anti-biofilm activity" .
October 2012 Gonzalez-Escobedo G, Gunn JS."Identification of Salmonella factors specifically regulated during biofilm formation on cholesterol (gallstone) surfaces" .
October 2012 Gonzalez-Escobedo G, Gunn JS."Identification of Salmonella factors specifically regulated during biofilm formation on cholesterol (gallstone) surfaces" .
March 2013 Koopman J, Marshall JM, Bhatiya A, Eguale T, Drew M, Gunn JS."Inhibition of Salmonella enterica biofilm formation through specific targeting of bacterial kinases with small-molecule adenosine mimetics" .
May 2013 Hoang K, Bachelder E, Borteh H, Rajaram MVS, Curry H, Ainslie K, Gunn JS, Schlesinger LS."Use Of Encapsulated AR-12 As A Host-Directed Agent To Control Intracellular Pathogens" .
March 2013 Neiger M, Gonzalez-Escobedo G, Gunn JS."Identification and Characterization of a Salmonella Hyper-biofilm isolate from mouse gallstones" .
April 2013 Marshall JM, Gunn JS."O-Ag Capsule-Deficient Mutants Of Salmonella Typhimurium Exhibit Attenuated Virulence And Elicit Protection Against Lethal Infection" .
August 2013 Koopman J, Marshall JM, Bhatiya A, Eguale T, Gunn JS."Inhibition Of Salmonella Enterica Biofilm Formation Through Specific Targeting Of Bacterial Kinases With Small-Molecule Adenosine Mimetics" .
November 2013 Borteh H, Hoang KV, Rajaram MVS, Curry H, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM."AR-12: a Broad Spectrum Host Cell-Directed Inhibitor of Intracellular Pathogens" .
April 2013 Hoang KV, Bachelder E, Borteh H, Rajaram MVS, Curry H, Ainslie K, Gunn JS, Schlesinger LS."Use of Encapsulated AR-12 As A Host-Directed Agent To Control Intracellular Pathogens" .
April 2013 Marshall JM, Gunn JS."O-ag capsule-deficient mutants of Salmonella Typhimurium exhibit attenuated virulence and elicit protection against lethal infection" .
April 2013 Gonzalez-Escobedo G, Gunn JS."The Gallbladder Epithelium as a Niche for Chronic Salmonella Carriage" .
April 2013 Hoang KV, Bachelder E, Borteh H, Rajaram MVS, Curry H, Ainslie K, Gunn JS, Schlesinger LS."Use of encapsulated AR-12 as a host-directed agent to control intracellular pathogens" .
May 2013 Marshall JM, Gunn JS."O-ag capsule-deficient mutants of Salmonella Typhimurium exhibit attenuated virulence and elicit protection against lethal infection" .
April 2013 Marshall JM, Gunn JS."O-Ag Capsule-Deficient Mutants Of Salmonella Typhimurium Exhibit Attenuated Virulence And Elicit Protection Against Lethal Infection" .
April 2013 Gonzalez-Escobedo G, Gunn JS."The Gallbladder Epithelium as a Niche for Chronic Salmonella Carriage" .
April 2013 Gavrilin MA, Curry HM, Shamaa O, Ghonime M, Tridandapani S, Gunn JS, Zahrt TC, Schlesinger LS, Wewers MD."Mechanisms of Francisella-Mediated Suppression of Cytokine Release in Human Monocytes" .
April 2013 Neiger M, Gonzalez G, Gunn JS."Identification and Characterization of a Salmonella Hyper-biofilm isolate from mouse gallstones" .
August 2013 Hoang K, Bachelder E, Borteh H, Rajaram MVS, Curry H, Ainslie K, Gunn JS, Schlesinger LS."Use of Encapsulated AR-12 As A Host-Directed Agent To Control Intracellular Pathogens" .

Inventions and Patents

Anti-infective agents against intracellular pathogens

Anti-francisella agents

Hydrogenase Deficient Bacterial Strains

 

Presentations

In vivo regulated Salmonella LPS modifications and intramacrophage survival

The Salmonella typhimurium PhoP-PhoQ regulon: Role in resistance to antimicrobial peptides

The Salmonella PhoP-PhoQ two-component regulatory system: Role in resistance to mammalian antimicrobial factors

In vivo regulated Salmonella LPS modifications: Role in pathogenesis

Characterization of Proteus mirabilis and Burkholderia cepacia Mechanisms of Resistance to IB-367

Salmonella's interactions with bile: Mechanisms of resistance and effect on invasion of epithelial cells

Microbial Pathogenesis Session

The Role of LPS Modification in Bacterial Virulence and Resistance to Antimicrobial Peptides

The Interaction of Salmonellae With Gallstone Surfaces

Identification of Proteus mirabilis and Burkholderia cepacia Mutants sensitive to Polymyxin and IB-367

The Role of The PhoPQ/PmrAB Two-Component Regulatory Cascade in Salmonella virulence

Identification of Proteus mirabilis and Burkholderia cepacia Mutants sensitive to Polymyxin and IB-367

Tissue-Specific Expression of Virulence Genes

The Interaction of Salmonella With Bile and Gallstone Surfaces

Resistance of Salmonella to Intestinal Antimicrobials

Bile and biofilms: a complex interaction involved in chronic Salmonella carriage?

Bile and biofilms: a complex interaction involved in chronic Salmonella carriage?

The Interaction of Salmonellae With Bile and Gallstone Surfaces

The Interaction of Salmonellae With Bile and Gallstone Surfaces

Salmonella Resistance and Response to Bile: Life in the Intestine and Gallbladder

Regulated mechanisms of bacterial resistance to antimicrobial peptides

LPS Modifications and Regulated Resistance to Antimicrobial Peptides in Salmonella typhimurium

Gallstone Biofilms and Bile Resistance/Response in Acute and Chronic Salmonella Infections

Covalent LPS Modifications and Regulated Resistance to Antimicrobial Peptides in Salmonella typhimurium

Covalent LPS Modifications and Regulated Resistance to Antimicrobial Peptides in Salmonella typhimurium

Bile Resistance/Response and Gallstone Biofilms in Typhoid Carriers

Covalent LPS Modifications and Regulated Resistance to Antimicrobial Peptides in Salmonella typhimurium

Covalent LPS Modifications and Regulated Resistance to Antimicrobial Peptides in Salmonella typhimurium

Bile Resistance/Response and Gallstone Biofilms in Typhoid Carriers

The Interaction of Salmonella With Bile and Gallstone Surfaces

Salmonella Resistance and Response to Bile: Life in the Intestine and Gallbladder

Regulated mechanisms of bacterial resistance to antimicrobial peptides

The Interaction of Salmonella with Bile and Gallstone Surfaces

Mechanisms of antimicrobial peptide resistance in diverse gram negative bacteria

Regulated Mechanisms Of Bacterial Resistance To Antimicrobial Peptide Killing

Regulated Mechanisms Of Bacterial Resistance To Antimicrobial Peptide Killing

Regulated LPS Modification and Resistance to Innate Immune Killing

Francisella LPS Structure and Phase Variation

Progress of the Tularemia RCE Project

Regulated Modification of Bacterial LPS

Please update record with Title

Salmonella Regulatory Networks, Cell Surface Modifications and Resistance to Innate Immune Killing

Regulation of Salmonella LPS Modification: Genes Required for Virulence and Resistance to Antimicrobial Peptides

The Interaction of Salmonella with Bile and Gallstone Surfaces

The Interaction of Salmonella with Bile and Gallstone Surfaces

Francisella LPS: phase variation, structure, and role in pathogenesis

Salmonella Host Adaptation and Survival in the Intestine and Gallbladder

Bacterial regulatory networks, LPS modification and resistance to antimicrobial peptides

Host sensing and bacterial surface modifications are important for Salmonella in vivo survival

Salmonella Host Adaptation and Survival in the Intestine and Gallbladder

Identification of an orphan response regulator required for Francisella virulence and transcription of pathogenicity island genes

“Something about Mary that we never knew: typhoid, biofilms and gallstones�

Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

“Salmonella Sensing of and Adaptation to the in vivo Environment�

“Salmonella Sensing of and Adaptation to the in vivo Environment�

“Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

“BSL-3 Research and Facilities at The Ohio State University�

“Salmonella Host Adaptation and Survival in the Intestine and Gallbladder�

“Salmonella Host Adaptation and Survival in the Intestine and Gallbladder�

“Chronic Carriage of Salmonella: Biofilms and Gallstones�

“Salmonella spp Response to Bile: Implications for Gallbladder Chronic Carriage�

. “Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

“Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

“Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

"Francisella acid phosphatases dephosphorylate and inactivate host NADPH oxidase complex components in human phagocytes�

“Biofilms, Gallstones and Salmonella Gallbladder Carriage�

“Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators�

Gallbladder carriage of Salmonella in mouse and man is enhanced by biofilm formation on gallstone surfaces

Gallbladder carriage of Salmonella in mouse and man is enhanced by biofilm formation on gallstone surfaces

Salmonella adaptation to the host environment: innate immune resistance and chronic carriage

Francisella Intramacrophage Survival: Phosphatases and Virulence Gene Regulators

Biofilms, Gallstones and Salmonella Gallbladder Carriage

Regulation of Francisella tularensis virulence factors by small non-coding RNAs

Regulation of Virulence and Immunosuppression in Francisella tularensis

Typhoid Mary: How is Salmonella gallbladder carriage established and maintained

Virulence Gene Regulation in Francisella tularensis

Secretion of the acid phosphatase AcpA in vitro and in vivo

Identification of Francisella tularensis regulatory determinants required for virulence and immune suppression

 

Professional Activities

present Co-Chair of session "Enteric Food and Waterborne Pathogens. 1st International Congress on Pathogens at the Human-Animal Interface (ICOPHAI).
 

Unpublished Works

Antibody-independent binding and activation of complement component C1 by wildtype and LPS O-antigen deficient Francisella tularensis

Identification of sRNAs that regulate virulence in Francisella tularensis