460 W 12th Ave
Columbus, OH 43210
Phone: (614) 247-2518
Associate Professor, Hematology
Catherine Heaphy (Former research assistant in my lab): 3 peer review manuscripts (one as first co-author in Blood), 2 reviews and several abstracts at international meetings. Currently in Univ of Indiana nursing school.
Nicole Stauffer (Former research assistant in my lab): 2 peer review manuscripts, several abstracts at international meetings ( 1 abstract as first name and presenter at ASH (oral presentation. Currently at Boston University, Phd immunology .
Caroline NA (Former research assistant in my lab): 2 peer review manuscripts, several abstracts at international meetings. Currently at Robert Wood Johnson New Jersey University, medical school, MD program.)
Parvathi Ranganathan (current post doc in my lab): Pelotonia fellowship award, 2 first author papers (1 plenary paper in Blood), 1 book chapter, currently working on training grant submission (all achievements since 09/2010).
Xueyan Yu (current post doc in my lab, since 2011): 1 first name paper in Blood, working on 2 high profile projects.
Sukhinder Sandhu (post doc in Croce lab and co-mentored with Dr. Croce): 1 paper under second revision at PNAS, 3 reviews.
Violaine Havelange ( MD and former phD student in my lab): (2 first name papers (Blood and Cancer), ASH Travel award , 3 reviews and a Discovery grant award from the Belgium government)
Graduate professional ( young faculty): Dr. Efebera; Major accomplishments: CTSA award, R21 submitted as multiple PI (SCORED 13 Impact/priority score NHI ( from 10-90) waiting for NOA), 1 clinical trial undergoing and accruing well, currently working on a K23 and an R01 submission.
PhD level: currently supervising and advising 3 people (Ranganathan, Yu and Sandhu).
Undergraduate level: 1research assistant (Jessica Hofsteter). I also often have students during summer rotations in my laboratory and provide career advice.
Ramiro Garzon is an assistant professor of medicine in the division of Hematology, Department of Internal Medicine and a member of the Molecular Biology and Cancer Genetics program at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA. He received his M.D. from the National University School of Medicine, Cordoba, Argentina. He trained in hematology and oncology at Thomas Jefferson University, Philadelphia, Pennsylvania, USA, and carried out a fellowship in leukemia at The Ohio State University. His research focuses on microRNA (miRNA) expression and function in normal hematopoiesis and leukemia. In particular, he is interested in dissecting the role of miRNAs in aberrant epigenetics and in developing novel miRNA-based therapies. He has made several original contributions in the field of miRNAs and leukemia, including the first evidence that miRNAs target the DNA methylation machinery. In 2008, he received the prestigious Kimmel Translational Award to help develop miRNA-based therapeutics to target aberrant epigenetics in acute myeloid leukemia (AML). More recently he received an R21 and R01 from the NIH. Dr. Garzon was initially appointed as instructor of Medicine in September of 2006 and was promoted to Assistant Professor of Medicine (tenure track) in April of 2007.
I participated in 2 thesis dissertations defense as committee member: Dr Tiziana Palumbo (Universidad de Catania, Italy 5/2009 and Dr. Violaine Havelange (University of Louvain, Brussels, Belgium in 5/2012).My participation in undergraduate research is described in detailed below.
I provided hematology clinic services to the OHIO correctional facilities from 2007 to 2010.
Sukhinder Sandhu (PhD student): 3 oral presentations about her work under my co-supervision in Annual meetings of the American Association for cancer research (AACR,Washington 2010), American society of Hematology (ASH, Orlando 2010 and the European Hematology association (EHA, Barcelona 2010), published 2 reviews and obtained a travel award to attend ASH meeting.
Marina Vasquez (PhD student): 1 poster presentation at ASH annual meeting in San Diego, 2011.
Tiziana Palumbo (PhD student): 1 poster presentation AACR, Washington 2006, 5 per review original papers as co-author. Currently at Harvard University as post -doc.
During the course of my career here at OSU I have developed collaborations within and outside the university that in my view as been very positive for the university.
First, I have helped to establish the OSU miRNA therapeutics group (Drs. Byrd, Chan, Liu, Muthusamy, Lee, Croce, Garzon and Marcucci) that hold meetings in a weekly basis. This group have achieved several milestones like the development of an ELISA based assay for miRNA detection, in vivo animal miRNA therapeutics trials and miRNA nanoparticle delivery systems. A total of 3 R01, 1 RC2 and Ohio grants were awarded from data generated by the group and are supporting his research. Several manuscripts has been published, discoveries made, patents filled (2). A PO1 is now to be submitted.
Second I contacted and developed a relationship with Santaris Pharma, the only pharmaceutical company in the world which has clinical trials using miRNAs therapies in humans. the goal is to develop miRNA therapies for acute leukemia. I have coordinated MTA process, collaborative process,, patent solving conflicts, and co develop with Tim Wright a drug development plan and lead discussions of partnership for miRNA therapy development.
Third, I have established research collaborations with outside researchers such as Drs. Blazar (univ of Minnesota )and Weiss (UPENN) that have resulted in publications and grant applications. More importantly b doing so i have brought to the institution expertise in an area that is currently lacking (GVHD and normal hematopoiesis biology).
|2010 - present||Parvathi Rangananthan, The Ohio State University. Graduated 2010.|
|2013||Nina Zitzer, The Ohio State University. Graduated 0.|
|2016||Betina McNeil, The Ohio State University. Graduated 2011.|
|2006 - 2008||Tiziana Palumbo, University of Catania. Graduated 2009. MicroRNA gene expression during ATRA differentiation of human APL|
|2006 - 2008||Tiziana Palumbo, University of Catania. Graduated 0.|
|2008 - 2009||Andrew Lee, The Ohio State University.|
|2009||Coleen Valencia, University of Notre Dame. Graduated 0.|
|2008 - 2010||Nicole Stauffer, The Ohio State University. Graduated 0.|
|2007 - 2011||Catherine E., The Ohio State University.|
|2009 - 2011||Sukhinder Sandhu, The Ohio State University. Graduated 2011. Role of miR-155 in B cell malignancies|
|2009 - 2011||Eugene KOh, The Ohio State University. Graduated 2011.|
|2009 - 2011||Marina Lipkin, The Ohio State University. Graduated 2011.|
|2010 - 2011||Jason Mendler, The Ohio State University. Graduated 0.|
|2007 - 2012||Violaine Havelange, Université Catholique de Louvain. Graduated 0. MicroRNAs: new actors in AML|
|2007 - 2012||Violaine Havelange, Université Catholique de Louvain. Graduated 2012.|
|2010 - 2012||Caroline Na, The Ohio State University. Graduated 0.|
|2011 - 2015||Xueyan Yu, The Ohio State University. Graduated 2005.|
Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia
|2008 - 2012||MCB|
|2008 - 2012||Blood|
|2009 - present||Journal of Nucleic Acid Investigation (JNAI)|
|2009||Journal of experimental and clinic research|
|2010||Seminars in Oncology|
|2010||Journal of Cellular and Molecular Medicine|
|2010 - 2011||Stem Cells and Development|
|2010 - 2011||Cancer Research|
|2010 - 2012||Leukemia Research|
|2010 - 2012||Leukemia|
|2010 - 2012||Clinical Cancer research|
|2010 - 2012||British journal of cancer|
|2010 - 2012||PLOS one|
|2010 - 2012||Molecular Cancer therapeutics|
|2010 - 2012||Heamatologica|
|2010 - 2012||Oncogene|
|2011||British Journal of Hematology|
|2011||Leukemia and Lymphoma|
|2011||Cell death and differentiation|
|2011 - 2012||EMBO|
|2012 - present||PLOS ONE|
|2012 - present||Datasets Papers in Imunology|
|2007 - 2008||Lauri Strauss Discovery award. Lauri Strauss Foundation.|
|2008 - 2009||Second highest patient satisfaction score in the OSU medical center (2008-2009). The Ohio State University.|
|2008 - 2010||Kimmel Translational Award. Kimmel Foundation for Cancer Research.|
|2009 - 2011||Leukemia SPORE Career Development award. NIH (NCI).|
|2010 - 2011||CAPS preceptorship recognition for dedicated service in the college of Medicine Educational Programs. College of Medicine.|
|2011 - present||Thompson Reuters KOL expert. Thompson Reuters.|
|2011||Molecular Biology and Cancer Genetics Program, Member. Molecular Biology and Cancer Genetics.|
|2013 - present||Member of the Molecular,Celullar and Developmental Biology. The Ohio State University.|
|2014 - present||Member of the Graduate Program in Comparative and Veterinary Medicine. Veterinary School.|
|2015 - present||Leukemia and Lymphoma Society Scholar Award. Leukemia and Lymphoma society.|
|2008 - present||Consultancy. Reckner mednet.|
|2009 - present||CTSA reviewer. OSU CTSA Pilot Award program. Columbus, OH.|
|2011 - present||ACS OSU Institutional seed grants. American Cancer Society. Columbus, OH.|
|2011 - present||Dr. Yvonne Efebera. OSU-Division of Hematology. Columbus, OH.|
|2012 - present||Grant Reviewer. Association for Internatioal Cancer Research.|
|2012 - present||Grant Reviewer. Cancer Research UK.|
|2009||Wiener Wissenschafts-, Forschungs- und Technologiefonds (WWTF), Austria, Vienna. Wiener Wissenschafts-, Forschungs- und Technologiefonds (WWTF), Austria, Vienna.|
|2009||Proposal reviewer. Hong Kong Research Grants Council.|
|2010||NHLSRT Development Grant. Medical Research Council of South Africa.|
|2010||Israeli Science Foundation Grant reviewer. Israeli Science Foundation.|
|2010||Scientific advisory board. Martell Foundation. Boston, MA.|
|2011||Grant Reviewer. Italian Association for Cancer Research.|
|2010 - 2012||Proposal review. Bernische Krebsliga.|
|2010 - 2012||Dutch Cancer Society. Dutch Cancer Society.|
|2010 - 2012||Grant review. Fondazione Cariplo.|
|2011 - 2012||Department of Defense (DOD) Discovery awards Blood cancer study section. Department of Defense.|
|2012||Grant Reviewer. Medical Research Council.|
|2012||Grant Reviewer. Eropean Research Council.|