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More About Ms. Shane-Carson


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2012 Kenny Rd
Columbus, OH 43221

Phone: (614) 293-6694

Email: shane-carson.1@osu.edu

 

Current OSU Appointment

Assistant Professor-Clinical, Human Genetics

 

Master/Graduate Advising

I have and continue to serve as an Academic Advisor / Program Coach for students in the Masters of Science Genetic Counseling Training Program at The Ohio State University. I also serve as a thesis committee member/thesis advisor for students in the genetic counseling graduate program.

Undergraduate, Graduate, and Professional Courses Taught

Narrative on Master's Degree Genetic Counseling Graduate Students Clinical Supervision: I have served as a primary clinical supervisory for over 16 genetic counseling graduate students since 2008 during their clinical rotations in the Division of Human Genetics at OSUWMC and in Pedatric Genetics at Nationwide Children's Hopsital. My responsibilites include mentoring, goal setting, and providing formative and summative assessment.

Narrative on M.D. Resident Clincial Supervision:
I have served as a primary clinical supervisor for over 10 NCH residents since 2008. My responsibilities include cilinical oversight and providing formative assessment.

Mentoring: I have also been the direct supervisor and mentor for two undergraduate students who have worked part-time as my genetic counseling assistants in the Division of Human Genetics at The Ohio State Wexner Medical Center.
Cortlandt Martin: 2014-16 - undergraduate student at The Ohio State University.
Halima Mohammed: 2016-present - undergraduate student at The Ohio State University.

Clinical Interest

Clinical Cancer Genetics, Telemedicine

Biographical

I obtained a Bachelor of Sciences degree in Biology from Seton Hill University in 2001. I also earned my Certification for Secondary Education in Biology, Chemistry, and Environmental Science from the State of Pennsylvania in 2001. I worked in a long-term substitute teaching position in high school Chemistry and Environmental Science in Pennsylvania for the spring of 2002. I then attended Wayne State University from 2002-2004, where I obtained my Masters of Science in Genetic Counseling. I obtained my Certification from the American Board of Genetic Counseling in 2005 and my License from the State Medical Board of Ohio in 2013, both of which remain current. From 2004-2009, I served as a genetic counselor in the Department of Pediatrics at Nationwide Children’s Hospital in Columbus, Ohio. I then assumed my current position a genetic counselor at The Ohio State University Clinical Cancer Genetics Program in December, 2009, was appointed as a Clinical Assistant Professor in 2009 (Auxillary Track), then as Assistant Professor in 2011 (Clinical Track). I am currently seeking appointment to Associate Professor in the Clinical Excellence pathway. I have furthered my education by completing a course in Health Outcomes Measurement at The Ohio State University in 2001 and an online Corsera course through Johns Hopkins University on Introduction to Systematic Review and Meta-Analysis in order to obtain skills to aid in performing clinical research in my clinical areas of expertise. I am also currently attending the Education Leadership Learning Community class in order to further develop my skills in clinical education.

My clinical responsibilities include providing genetic risk assessment and counseling for patients and families at risk for a wide range of hereditary cancer syndromes. These services are provided through a variety of service delivery models, including: genetic counseling only appointment, genetic counseling/physician co-appointments, multi-disciplinary clinics, and telegenetics. I currently staff an average of 7 half-day clinics per week, and manage the administrative aspects of triage and scheduling for my telegenetic clinics. I take an active role in networking with other health care providers, both within and outside Ohio State, to provide clinical care to patients and to develop, collaborate, and enroll patients in various clinical research studies. I am achieving a regional and national reputation for my work in telegenetics, and was recently appointed by the National Society of Genetic Counselors to perform a systematic review analysis of telegenetic counseling to be used in the development of a practice guideline for utilizing telemedicine in genetic counseling. I have also submitted a manuscript, which is currently in review by the Journal of Genetic Counseling, regarding a description of my clinical model for providing telegentic counseling and testing to patients for hereditary cancer syndromes.

I participate actively in clinical research. I receive salary support through a grant funded by the Ohio Department of Health, for which I serve as a core workgroup member of the Ohio Cancer Genetics Network. My primary research with this group entails utilizing cancer registrar data to evaluate genetics referral and uptake of appointments for standard indications, as part of a statewide Q&A project. This project identifies areas for improvement with the goal of implementing and evaluating interventions to increase access to care for hereditary cancer genetic counseling and testing in appropriate cohorts of patients. I currently serve as the principal investigator for the Ohio State cohort of the INHERIT study for lung cancer, with the goal of determining the incidence and penetrance of the T790M EGFR germline mutation for lung cancer, and evaluating the effectiveness of CT scans as a screening tool for unaffected carrier family members. I am working with the Health IT Special Interest Group of the National Society of Genetic Counselors to complete a manuscript evaluating genetic counselors clinical use of electronic medical records across subspecialties, with the goal of identifying global opportunities for modification of EMR’s to better adapt to the clinical application of patients' genetic information.

I take an active role in the clinical education of genetic counseling masters students, 4th year medical students, oncology fellows, and genetics residents through the coordination, supervision, and evaluation of clinical rotations. I also take an active role in teaching, primarily through Practice-Based Learning and Flipped Classroom techniques, for genetic counseling and medical students. Of note, I was appointed by the National Society of Genetic Counselors to serve on the Undergraduate Training of Residents in Genomics workgroup. This is an international project, funded by NCI, to develop practice-based learning education modules in genomic medicine, to be used in the training of undergraduate medical students, and adapted to other students learning about genomic medicine. As a result of my role in this group, I have been asked to consult on other projects, and to present at national meetings. I also take an active role in providing educational talks to the lay-public, undergraduate and graduate students, and other health care professionals.

Continuing Education, Extension, and Other Courses Taught

Throughout my career, I have attained diverse experiences in providing clinical education and mentoring in cancer genetics. For the Ohio State University Genetic Counseling Master’s Degree Program, I serve as a course director, guest instructor, program coach/student advisor, thesis advisor, and clinical cancer genetics rotation coordinator. I have served as a primary clinical supervisor for over 20 genetic counseling graduate students from 2008-2014 during their clinical rotations in the Division of Human Genetics at OSUWMC and in Pediatric Genetics at Nationwide Children’s Hospital. My responsibilities include mentoring, goal setting and providing formative and summative assessment. I currently play a key role in providing supervision for genetic counseling students in cancer genetics, and typically have 1-2 students on rotation with me each semester throughout the year. I also serve as the rotation coordinator and clinical supervisor for genetic residents through Nationwide Children’s Hospital (NCH), as well as for 4th year medical students’ elective rotations in genetics. I have served as a primary clinical supervisor for over 10 NCH genetic residents and cytogenetics fellows since 2008. This entails ensuring that medical students and fellows are able to attain a diverse experience in cancer genetics, medical genetics, cardiovascular genetics, and neurogenetics. My responsibilities include clinical oversight and providing formative assessment. Currently, I am working with Dr. Joanne Jeter to implement a new cancer genetics rotation for fellows in medical oncology.

My experience in educational outreach and program development has had a national impact through service on national committees. Last year I was appointed by NSGC to serve on the Undergraduate Training in Genomics (UTRIG) national workgroup, which is funded by a NCI grant to develop educational programs in genomic medicine for undergraduate medical education programs. As a result of my work for UTRIG, I was asked this year to consult in the development of genomics educational modules in cardiology, neurology, and ophthalmology for the Inter-Society Coordinating Committee (ISCC) for Practitioner Education in Genomics, Innovative Approaches Working Group. I am also presenting a workshop at the 2017 NSGC Annual Conference called “Train the Trainer” in order to teach genetic counselors how to utilize the UTRIG curriculum to implement practice based learning and flipped classrooms in the education of students in genomics. In 2017 I was also appointed to serve a 3-year term as a member of the Program Review Committee for the Accreditation Council for Genetic Counseling.


I have also taken an active role in other regional and national education efforts. I have been invited to give CNE, CME, and genetic counseling CEU lectures on genetics at various sites throughout Ohio and at regional meetings. I also have developed online educational content for the Ohio Department of Health and the National Society of Genetic Counselors. In 2016 I served on the planning committee for the Ohio State genetic counselors annual education meeting.

Locally, at Ohio State, I provide lectures to oncology nurses and medical students in genetics. I also serve as a guest instructor for the Ohio Dominican University Physician Assistant Program genetics course.


I also have taken an active role in patient education. I have served as a member of the planning committee for our annual Beyond Risk patient conference, for patients with Hereditary Breast and Ovarian Cancer syndrome and Lynch syndrome. In 2016 I was the chair of the planning committee for this conference.

Noteworthy Graduate Narrative

I am currently serving as a thesis advisor for genetic counseling masters student Brenda Zuniga, who was awarded a student research grant through the National Society of Genetic Counselors Health IT Special Interest group for her project “Assessing the utilization and implementation of telemedicine services among genetic counselors practicing in various clinical settings.”

Advising Narrative

I served as a mentor to Cortlandt Martin as an undergraduate student. She was accepted this year to the Case Western Reserve University Genetic Counseling Master Degree Program. She also served as a co-author for my manuscript, Logistics and Uptake of Genetic Testing for Patients Referred for Telegentic Counseling for Cancer” which has been submitted and is currently under review by the Journal of Genetic Counseling.

Published Works

Most of my previously published works entail collaborative case series reporting on the clinical findings of patients identified with genetic disorders.

Research Funding

Since my role is primarily clinical, most of my funding is provided for clinical care. Currently, 20% of my salary is funded by the Ohio Department of Health for the provision of cancer genetic counseling services, as well as for research and educational outreach that serves to increase the provision of genetic counseling services throughout the state of Ohio. Due to my clinical experience, I receive funding to participate in other research projects for: consultative purposes in project development and clinical implementation, the provision of genetic counseling as part of research, and enrollment and data collection of genetic counseling patients for clinical research. The additional projects, which tie in directly to the clinical care of my patients, currently fund an additional 9% of my salary.

Academic Advising

I have been the direct supervisor and mentor for 2 undergraduate students who have worked part-time as my genetic counseling assistant in the Division of Human Genetics at The Ohio State University Wexner Medical Center.

Academic Advising

2014 - present , The Ohio State University.
2015 - present Maggie Stein, The Ohio State University. Assessing Geography as a Barrier in Choosing to Undergo Genetic Testing in a Cohort of Young Women with Breast Cancer.
2016 - present Paul Hudson, The Ohio State University.
2016 - present Brenda Zuniga, The Ohio State University. Assessing the utilization and implementation of telemedicine services among genetic counselors practicing in various clinical settings.
2016 - present Halima Mohammed, The Ohio State University.
2014 - 2016 Cortlandt Martin, The Ohio State University. Graduated 2016.
2014 - 2016 Donika Saporito, The Ohio State University. Graduated 2016.
 

Licenses

2001 - present Pennsylvania State Secondary Education: Commonwealth of Pennsylvania
2005 - present Certified Genetic Counselor: American Board of Genetic Counseling
2013 - present Genetic Counselor License, State Medical Board of Ohio: State Medical Board of Ohio
 

Clinical Services

12/01/2009 Cancer Genetic Counselor (Clinical Cancer Genetics Program, The Ohio State University)

Conferences

Sommer A, Shane K, Pastore M. "Trisomy 20p." DW Smith Conference on Morphogenesis and Moprhology. .

Sommer A, Shane K, Pastore M, Cottrell C, Lamb-Thrush D, Gastier-Foster J. "Noonan syndrome and SOS1 Mutation Phenotype." DW Smith Workshop on Malformations and Morhpogenesis. .

Maegan E Roberts, Megan Marshall, Susan Hiraki, Kate P. Shane, Rachel T Klein, Zhixiong Xu, Kathleen S Hruska. "MSH2 initiation codon variants do not predispose to classic Llynch syndrome." Collaborative Group of the Americas on Inherited Colorectal Cancer. .

Nichole A Morman, MS LGC< Kate Shane, MS, LGC, Lindsey Byrne, MS, LGC, Karen Smith, RHIA, CTR, Laura L. Vondenhuevel, RHIT, CTR, Elayna Freese, CTR, Maria Teresa Ramirez, CTR and Karen Huelsman, MS, LGC. "Genetic Counseling Uptake among Gynecologic Oncology Registry Patients: A Collaborative Approach in Ohio." 2017 National Cancer Registrars Association Annual Conference. .

Lindsey Byrne, MS, LGC, Karen Huelsman, MS, LGC, Nichole A. Morman, MS, LGC, Elayna Freese, CTR, Karen Smith, RHIA, CTR, Laura L. Vondenhuevel, RHIT, CTR, , Maria Teresa Ramirez, CTR, and Kate Shane, MS, LGC. "Genetic Counseling Referrals among Cancer Registry Patients Meeting NCCN Guidelines: An Ohio Study." The National Society of Genetic Counselors Annual Meeting. .

 

Degrees

2001 B.S., Seton Hill College

2004 M.S., Wayne State University

 

Editorial Activities

2015 - present Genetics in Medicine
2015 - present Journal of Genetic Counseling
2015 - present BMC Cancer
2016 PLOS ONE
2017 - present Cancer Genetics
 

Honors

2017 - present Lead, Serve, Inspire Award: Foundations in Medicine II Block. College of Medicine.
 

Journal Articles

Marshall CR; Young EJ; Pani AM; Freckmann ML; Lacassie Y; Howald C; Fitzgerald KK; Peippo M; Morris CA; Shane K; Priolo M; Morimoto M; Kondo I; Manguoglu E; Berker-Karauzum S; Edery P; Hobart HH; Mervis CB; Zuffardi O; Reymond A; Kaplan P; Tassabehji M; Gregg RG; Scherer SW; Osborne LR. "Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11.." American Journal Of Human Genetics. Vol. 83, no. 1. (July 2008.): 106-.

Coppinger J; McDonald-McGinn D; Zackai E; Shane K; Atkin JF; Asamoah A; Leland R; Weaver DD; Lansky-Shafer S; Schmidt K; Feldman H; Cohen W; Phalin J; Powell B; Ballif BC; Theisen A; Geiger E; Haldeman-Englert C; Shaikh TH; Saitta S; Bejjani BA; Shaffer LG. "Identification of familial and de novo microduplications of 22q11.21-q11.23 distal to the 22q11.21 microdeletion syndrome region.." Human Molecular Genetics. Vol. 18, no. 8. (April 2009.): 1377-.

Ballif BC; Theisen A; Rosenfeld JA; Traylor RN; Gastier-Foster J; Thrush DL; Astbury C; Bartholomew D; McBride KL; Pyatt RE; Shane K; Smith WE; Banks V; Gallentine WB; Brock P; Rudd MK; Adam MP; Keene JA; Phillips JA 3rd; Pfotenhauer JP; Gowans GC; Stankiewicz P; Bejjani BA; Shaffer LG. "Identification of a recurrent microdeletion at 17q23.1q23.2 flanked by segmental duplications associated with heart defects and limb abnormalities.." American Journal Of Human Genetics. Vol. 86, no. 3. (March 2010.): 454-.

A. Theisen, J.A. Rosenfeld, K.Shane, K.L. McBride, J.F. Atkin, C. Gaba, J. Hoo, T.W. Kurczynski, R.E. Schnur, L.B. Coffey, E.H. Zackai, L. Schimmenti, N. Friedman, M. Zabukovec, S. Ball, R. Pgon, A. Lucas, C.K. Brasington, J.E. Spence, S. Sparks, VB. Banks, W. Smith, T. Friedberg, P.R. Wyatt, M. Aust, R. Tervo, A. Crowley, D. Skidmore, A.N. Lamb, B. Ravnan, T. Sahoo, R. Schultz, B.S. Torchia, M. Sgro, D. Chitayat, L.G. Shaffer. "Refinement of the Regions for Split Hand/Foot Malforamtion5 on 2q31.1." Molecular Syndromology. Vol. 1, no. 5. (January 2011.): 262-271.

Krone N, Reisch N, Idkowiak J, Dhir V, Ivison HE, Hughes BA, Rose IT, O'Neil DM, Vijzelaar R, Smith MJ, Macdonald F, Cole TR, Adolphs N, Barton JS, Blair EM, Braddock SR, Collins F, Cragun DL, Dattani MT, Day R, Dougan S, Feist M, Gottschalk ME, Gregory JW, Haim M, Harrison R, Haskins Olney A, Hauffa BP, Hindmarsh PC, Hopkin RJ, Jira PE, Kempers M, Kerstens MN, Khalifa MM, Köhler B, Maiter D, Nielsen S, O'Riordan SM, Roth CL, Shane KP, Silink M, Stikkelbroeck NM, Sweeney E, Szarras-Czapnik M, Waterson JR, Williamson L, Hartmann MF, Taylor NF, Wudy SA, Malunowicz EM, Shackleton CH, Arlt W.. "Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.." J Clin Endocrinol Metab. Vol. 97, no. 2. (February 2012.): E257-67.

Alyaqoub,Fadel; Pyatt,Robert,E; Bailes,Andrea; Brock,Amanda; Deeg,Carol; McKinney,Aimee; Astbury,Caroline; Reshmi,Shalini; Shane,Kate,P; Thrush,Devon,Lamb; Sommer,Annemarie; Gastier-Foster,Julie,M. "12q14 microdeletion associated with HMGA2 gene disruption and growth restriction." AMERICAN JOURNAL OF MEDICAL GENETICS PART A. Vol. 158A, no. 11. (November 2012.): 2925-2930.

 

Presentations

"The Value of Genetic Counselors in Genetic Testing for Hereditary Breast-Ovarian Cancer.." Presented at National Society of Genetic Counselors Annual Education Conference, Boston. (October 2012)

"Initial results of a prospective, multicenter trial to study inherited lung cancer risk associated with germline EGFR T790M: INHERIT EGFR.." Presented at American Society of Clinical Oncology Annual Meeting, . (May 2015)

"Teaching Genomic Medicine: A Train-the-Trainer Workshop." Presented at National Society of Genetic Counselors Annual Meeting, Columbus. (September 2017)

"Genetic Counseling Referrals among Cancer Registry Patients Meeting NCCN Guidelines: An Ohio Study." Presented at Regional Cancer Registrar Meeting, Cincinnati. (September 2017)

"Genetic Counseling Referrals among Cancer Registry Patients Meeting NCCN Guidelines: An Ohio Study." Presented at 20178 National Cancer Registrars Association Annuyal Confernece, . (March 2017)

 

Professional Activities

2014 - present Clinic Care Conference Coordinator - Volunteer. OSU Clinical Cancer Genetics.
2010 - 2015 Clincal Volunteer Service. OSU Clinical Cancer Genetics. Columbus, OH.
2015 - 2016 Committee Chair - Volunteer. OSU Clinical Cancer Genetics.
 

Unpublished Works

Takehito Shukuya, Sanipkumar Patel, Kate Shane-Carson, Kai He, Erin M. Bertino, Konstantin Shilo, Gregory A. Otterson, David P. Carbone.. Lung Cancer patients with Germline Mutations: A Single Institution Retrospective Study. July 2017.

Shane-Carson, Kate P. and Martin, Cortlandt. Logistics and Uptake of Genetic Testing for Patients Referred for Telegenetic Counseling for Cancer.. June 2017.

Kate Shane-Carson, Doreen Agnese, Kristen Zajo. Case Report: A patient with likekly pathogenic mutations in BRCA1 and TP53.

Kate Shane-Carson, Megan Frone, Willonie Mendonca, Lola Cook-Shukla, Heather Fectreau, Karen Vikstrom. How are genetic counselors utilizing the EMR, and it is meeting our needs?.