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Cardiovascular Clinical Trials

The Heart and Vascular Research Organization (HVRO)

Our faculty members have made great progress in patient care through their deep involvement with advancing research.


Clinical Trials

Following is a list of the types of clinical trials being conducted by the Heart and Vascular Research Organization

  •  Atrial Fibrillation Studies
  •  Heart Failure Studies
  •  Interventional Cardiovascular Studies
  •  Cardiac Imaging Studies
  •  Cardiac Surgery Studies
  •  Pulmonary Hypertension Studies
  •  Sleep Breathing Disorders Studies
  •  Stem Cell Treatment Studies
  •  Vascular Disease and Treatments

For more information about Cardiovascular Research Studies, or additional information on clinical trials available at Ohio State University visit Ohio State University Medical Center or email Cardiovascular Research.

If you would like to be contacted to see if you qualify to participate in a clinical trial, visit Screening Survey

Other resources include: U.S. National Institutes of Health's ClinicalTrials.gov.


What is the HVRO?

In 2003, a dedicated group of nurses, coordinators, and administrative staff were gathered together to create the Cardiovascular Clinical Research Unit currently known as the Heart and Vascular Research Organization (HVRO). Since its inception the HVRO has grown considerably, to handling more than 150 research studies.

HVRO manages all aspects of clinical research including:

  • Personnel
  • Study feasibility
  • Protocol implementation
  • Regulatory management
  • Contract and budget development
  • Internal auditing
  • Promotion and marketing

Approximately twenty percent of these active clinical studies have OSU Cardiovascular Medicine physicians are serving as National PIs, Steering Committee members, or Data Safety Monitoring.

HVRO Study Types and Research Areas

The HVRO manages many different types of studies, such as investigator-initiated single-center studies, NIH-sponsored multi-center trials, and industry-sponsored trials.

Research Areas

  • Heart failure
  • Transplant/cardiothoracic surgery
  • Interventional Cardiology
  • Electrophysiology
  • Non-invasive Imaging
  • Genotyping
  • Exercise and Prevention
  • Sleep Breathing disorders
  • Pulmonary hypertension
  • Vascular Disease and Surgery
  • Stem Cell Treatments

The HVRO is divided into five main specialized teams; Intervention, Electrophysiology, Heart Failure, Surgery, Sleep Breathing Disorders.

Housed within the HVRO are several core laboratories testing clinical trials Echocardiographs, Electrocardiograms, and Cardiac Magnetic Resonance Imaging.

The HVRO, in partnership with patients, health care professionals, and researchers, provides national leadership in clinical trials investigating cardiovascular drug, device, pharmacogenetic and imaging therapies and procedures. By linking the Ross Heart Hospital and Davis Heart and Lung Research Institute, the HVRO provides an opportunity for clinical researchers and basic scientists to collaboratively improve patient care and outcomes. It is through this mutual effort that we are able to identify the needs of individual patients and aid in the advancement of personalized health care.