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Dr. Whisler's OSUPro profile


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480 W 9th Ave
Columbus, OH 43210

 

Current OSU Appointments

Faculty Emeritus, Immunology & Rheumatology

"Appointment", OSU Physicians

 

Clinical Interest

Bursitis, Osteoarthritis, Rheumatoid Arthritis and Vasculitis

Books

Rothermic NO, Whisler RL. Rheumatoid Arthritis. /: Academic Press, January 1985.

 

Certifications

1973 - present Internal Medicine: American Board of Internal Medicine
1976 - present Internal Medicine: American Board of Internal Medicine
1998 - present Clinical DXA Bone Densitometry: The International Society for Clinical Densitometry
 

Chapters in Books

Whisler RL. "Arthralgias and nasal inflammation (case history)." In Contemporary Internal Medicine, Clinical Case Studies. Vol. 2. Edited by Bowen J, Mazzaferri EL. 83-92. [no place]: Plenum Pub Co, January 1989.

Whisler RL, Gray LS, Hackshaw KV. "Rheumatology: A Clinical Overview." In In Clinics in Podiatric Medicine and Surgery. -. [no place]: WB Saunders Publishers, January 2002.

Whisler RL, Gray LS, Hakshaw KV. "Rheumatology: A Clinical Overview." In In Clinics in Podiatric Medicine and Surgery. -. [no place]: WB Saunders, January 2010.

 

Conferences

Zhang H, Jones KH, Davis WB, Whisler RL, Panganamala RV, Cornwell DG. "Oxidized low density lipoproteins in smooth muscle cell cultures: differential effects on prostanoid synthesis and viability." Proceedings International Symposium on Vitamin E. (December 1986). .

 

Degrees

1964 B.S., Ohio University

1968 M.D., The Ohio State University

 

Editorial Activities

present Central Society Clinical Research
present American Journal of Hematology
present American Federation Clinical Research
present Journal of Clinical Investigation
present Journal Clinical Immunology
present J National Cancer Institute
present J National Cancer Institute
present J Clin Immunology
present Arthritis Rheumatism
present National American Rheumatism Association
present Lymphokine and Cytokine Research
present Lipids
present Journal of Interferon and Cytokine Research
1988 - present Division Research Grants, NIH, R01's and National Institute on Aging, P02s, Center Grants, T32s
 

Honors

0 Medical Honorary. Alpha Omega Alpha.
1973 Residency Award. Department of Medicine.
1977 Phillip S. Hench Scholarship Award in Rheumatology. Mayo Foundation.
1979 Young Investigator Research Award. National Institute of Allergy and Infectious Disease, NIH.
1980 Departmental Research Award.
1982 Landacre Faculty Research Teaching Award.
1987 Academic Research Leadership Award. National Institute on Aging, NIH.
2002 Martha Morehouse Professor of Rheumatology.
2005 Metz Distinguished Physician Award.
 

Journal Articles

Whisler RL; Stobo JD. "Heterogeneity of murine regulatory T cells. I. Subpopulations of amplifier and suppressor T cells.." The Journal Of Experimental Medicine. Vol. 144, no. 2. (August 1976.): 398-.

Whisler RL, Stobo JD. "Heterogeneity among suppressor T cells." Regulatory Mechanisms in Lymphocyte Activation. (January 1977.): 748-750.

Whisler RL; Stobo JD. "Suppression of humoral and delayed hypersensitivity responses by distinct T cell subpopulations.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 121, no. 2. (August 1978.): 539-542.

Unverferth DV; Beman FM; Ryan JM; Whisler RL. "Reiter's aortitis with pericardial fluid, heart block and neurologic manifestations.." The Journal Of Rheumatology. Vol. 6, no. 2. (March 1979.): 232-236.

Luzar MJ, Whisler RL, Hunder CG. "Syndrome of inappropriate antidiuretic hormone secretion in association with temporal arteritis." J Rheumatol. Vol. 9, no. 6. (January 1980.): 951-960.

Bobak D, Whisler RL. "Human B lymphocyte colony responses. I. General characteristics and modulation by monocytes." Journal of Immunology. Vol. 125, (January 1980.): 2764-2769.

Yates AJ, Hitchcock CL, Stewart SS, Whisler RL. "Immunological properties of gangliosides." Cell Surface Glycolipids. Vol. 24, (January 1980.): 419-433.

Yates AJ; Mattison SL; Whisler RL. "Effect of concanavalin A on ganglioside metabolism of human lymphocytes.." Biochemical And Biophysical Research Communications. Vol. 96, no. 1. (September 1980.): 211-218.

Whisler RL; Yates AJ. "Regulation of lymphocyte responses by human gangliosides. I. Characteristics of inhibitory effects and the induction of impaired activation.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 125, no. 5. (November 1980.): 2106-2111.

Opremcak EM; Bakenhaster K; Whisler RL. "NK and K cell characteristics of human lymphocytes enriched for subpopulations isolated from NK tumor cell conjugates.." Cellular Immunology. Vol. 58, no. 2. (March 1981.): 415-425.

Whisler RL; Newhouse Y. "Amplification and suppression of human T cell proliferative responses by alloactivated T cells.." Clinical And Experimental Immunology. Vol. 44, no. 1. (April 1981.): 100-107.

Whisler RL; Balcerzak SP; Murray JL. "Heterogeneous mechanisms of imparied lymphocyte responses in non-Hodgkin's lymphoma.." Blood. Vol. 57, no. 6. (June 1981.): 1081-1087.

Whisler RL; Bobak DA; Newhouse YG. "Human B lymphocyte colony responses. II. The role of T cells in the enhancement of colony growth.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 127, no. 5. (November 1981.): 1758-1762.

Whisler RL, Newhouse YG. "Cellular characteristics and specificity or alloactivated regulatory T cells modulation T cell mediated responses." Cellular Immunology. Vol. 60, (January 1981.): 393-401.

Whisler RL; Bakenhaster K; Opremcak EM. "Autologous mechanisms generating natural killer activity within human peripheral lymphocytes depleted of NK target-binding cells.." Cellular Immunology. Vol. 66, no. 2. (January 1982.): 342-351.

Whisler RL, Newhouse YG. "Characteristics and differential T cell dependency of human B cell colony precursors." Cellular Immunology. Vol. 67, (January 1982.): 346-354.

Whisler RL; Newhouse YG. "Inhibition of human B lymphocyte colony responses by endogenous synthesized hydrogen peroxide and prostaglandins.." Cellular Immunology. Vol. 69, no. 1. (May 1982.): 34-45.

Whisler RL; Newhouse YG; Lachman LB. "Heterogeneity of human monocyte subsets in the promotion of B cell colonies and the role of interleukin 1.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 129, no. 2. (August 1982.): 455-460.

Luzar MJ; Whisler RL; Hunder GG. "Syndrome of inappropriate antidiuretic hormone secretion in association with temporal arteritis.." The Journal Of Rheumatology. Vol. 9, no. 6. (November 1982.): 957-.

Whisler RL; Newhouse YG; Mortensen RF. "C-reactive protein- (CRP) mediated modulation of human B cell colony development.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 130, no. 1. (January 1983.): 248-253.

Whisler RL. "Characterization of human B cell colony responses.." Lymphokine Research. Vol. 2, no. 2. (January 1983.): 43-48.

Grever MR; Siaw MF; Coleman MS; Whisler RL; Balcerzak SP. "Inhibition of K and NK lymphocyte cytotoxicity by an inhibitor of adenosine deaminase and deoxyadenosine.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 130, no. 1. (January 1983.): 365-369.

Whisler RL; Wajda KJ; Newhouse YG. "Phenotypic characteristics of peripheral blood T cells regulating colony growth by nontransformed human B lymphocytes.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 130, no. 2. (February 1983.): 665-670.

Tsakalos ND; Lachman LB; Newhouse YG; Whisler RL. "Lipopolysaccharide (LPS) modulation of human monocyte accessory cell function in promoting T-cell colonies: inability of LPS and IL-1 to abrogate the need for monocytes with high HLA-DR expression.." Cellular Immunology. Vol. 83, no. 2. (February 1984.): 229-241.

Whisler RL; Murray JL; Roach RW; Balcerzak SP. "Characterization of multiple immune defects in human malignant lymphoma.." Cancer. Vol. 53, no. 12. (June 1984.): 2628-2634.

Whisler RL; Lindsey JA; Proctor KV; Morisaki N; Cornwell DG. "Characteristics of cyclosporine induction of increased prostaglandin levels from human peripheral blood monocytes.." Transplantation. Vol. 38, no. 4. (October 1984.): 377-381.

Yates AJ; Icard-Liepkalns C; Sirinek LP; Stephens RE; Elder PJ; Liepkalns VA; Whisler RL. "Natural killer activity against cultured human neural tumor and fetal brain cells.." Cellular Immunology. Vol. 90, no. 2. (February 1985.): 485-492.

Yates AJ; Stephens RE; Markowitz DL; Elder PJ; Sirinek LP; Whisler RL. "Resistance to natural killer cytolysis and neutral glycolipid composition of cultured human glioma and fetal brain cells.." Journal Of Neuropathology And Experimental Neurology. Vol. 44, no. 4. (July 1985.): 371-383.

Ennist DL; Jones KH; St Pierre RL; Whisler RL. "Functional analysis of the immunosenescence of the human B cell system: dissociation of normal activation and proliferation from impaired terminal differentiation into IgM immunoglobulin-secreting cells.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 136, no. 1. (January 1985.): 99-105.

Opremcak EM; Whisler RL; Dangel ME. "Natural killer cells against human corneal endothelium.." American Journal Of Ophthalmology. Vol. 99, no. 5. (May 1985.): 524-.

Rothermich NO, Whisler RL. "Rheumatoid arthritis." Academic Press. (January 1985.): -.

Opremcak, E, M; Whisler, R, L; Dangel, M E. "Natural killer cells against human corneal endothelium.." American journal of ophthalmology. Vol. 99, no. 5. (January 1985.): 524-529.

Whisler RL; Newhouse YG; Lachman LB. "Differential abilities of human peripheral blood monocytes quantitatively or qualitatively differing in HLA-DR and HLA-DS expression to support B cell activation in liquid and semisolid cultures.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 135, no. 1. (July 1985.): 172-179.

Whisler RL; Lindsey JA; Proctor KV; Newhouse YG; Cornwell DG. "The impaired ability of human monocytes to stimulate autologous and allogeneic mixed lymphocyte reactions after exposure to cyclosporine. Associated alterations of HLA-DR expression and physical characteristics of monocytes.." Transplantation. Vol. 40, no. 1. (July 1985.): 57-61.

Whisler RL; Newhouse YG; Ennist D; Lachman LB. "Human B-lymphocyte colony responses: suboptimal colony responsiveness in aged humans associated with defective function of B cells and monocytes.." Cellular Immunology. Vol. 94, no. 1. (August 1985.): 133-146.

Whisler RL; Newhouse YG. "Immunosenescence of the human B cell system: impaired activation/proliferation in response to autologous monocytes pulsed with Staph protein A and the effects of interleukins 1 and 2 compared to interferon.." Lymphokine Research. Vol. 4, no. 4. (September 1985.): 331-337.

Tsakolos ND; Theoharides TC; Hendler ED; Goffinet J; Dwyer JM; Whisler RL; Askenase PW. "Immune defects in chronic renal impairment: evidence for defective regulation of lymphocyte response by macrophages from patients with chronic renal impairment on haemodialysis.." Clinical And Experimental Immunology. Vol. 63, no. 1. (January 1986.): 218-277.

Whisler RL; Newhouse YG. "Function of T cells from elderly humans: reductions of membrane events and proliferative responses mediated via T3 determinants and diminished elaboration of soluble T-cell factors for B-cell growth.." Cellular Immunology. Vol. 99, no. 2. (May 1986.): 422-433.

Basu SK; Whisler RL; Yates AJ. "Effects of lectin activation on sialyltransferase activities in human lymphocytes.." Biochemistry. Vol. 25, no. 9. (May 1986.): 2577-2581.

Whisler RL; Proctor VK; Downs EC; Mortensen RF. "Modulation of human monocyte chemotaxis and procoagulant activity by human C-reactive protein (CRP).." Lymphokine Research. Vol. 5, no. 3. (June 1986.): 223-228.

Zhang H, Jones KH, Davis WB, Whisler RL, Panganamala RV, Cornwell DG. "Oxidized low densitylipoproteins in smooth muscle cell cultures: Differential effects on prostanoid synthesis and viability." Proceedings International Symposium on Vitamin E. (January 1986.): -.

Kaseki H; Kim EY; Whisler RL; Cornwell DG. "Effect of an oral dose of vitamin E on the vitamin E and cholesterol content of tissues of the vitamin E-deficient rat.." The Journal Of Nutrition. Vol. 116, no. 9. (September 1986.): 1631-1639.

Whisler RL; Newhouse YG; Mortensen RF. "C-reactive protein reduces the promotion of human B-cell colony formation by autoreactive T4 cells and T-cell proliferation during the autologous mixed-lymphocyte reaction.." Cellular Immunology. Vol. 102, no. 2. (October 1986.): 287-298.

Olsen RG, Tarr MJ, Mathes LE, Whisler RL, DuPleissis D, Schultz EJ, Blakeslee JR. "Serological and virological evidence of human T-lymphotrophic virus in systemic lupus erythematosus." Medical Microbiology and Immunology. Vol. 176, (January 1987.): 53-64.

Downs EC; Cornwell DG; Proctor VK; Whisler RL. "IL 1 and bacterial lipopolysaccharide increase the ability of human endothelial cells to bind peripheral blood monocytes.." Lymphokine Research. Vol. 6, no. 4. (September 1987.): 351-355.

Yates AJ; Markowitz DL; Stephens RE; Pearl DK; Whisler RL. "Growth inhibition of cultured human glioma cells by beta-interferon is not dependent on changes in ganglioside composition.." Journal Of Neuropathology And Experimental Neurology. Vol. 47, no. 2. (March 1988.): 119-127.

Hudson NP; Whisler RL. "Update: treatment of rheumatoid disease.." Comprehensive Therapy. Vol. 14, no. 10. (October 1988.): 51-56.

Whisler RL. "Arthralgias and nasal inflammation (case history)." Contemporary Internal Medicine. Vol. 2, (January 1989.): -.

Whisler RL; Cornwell DG; Proctor KV; Downs E. "Bacterial lipopolysaccharide acts on human endothelial cells to enhance the adherence of peripheral blood monocytes.." The Journal Of Laboratory And Clinical Medicine. Vol. 114, no. 6. (December 1989.): 708-716.

Zhang H; Kaseki H; Davis WB; Whisler RL; Cornwell DG. "Mechanisms for the stimulation of prostanoid synthesis by cyclosporine and bacterial lipopolysaccharide.." Transplantation. Vol. 47, no. 5. (May 1989.): 864-871.

Kazimer RM; Whisler RL; Stephens RE; Pearl DK; Yates AJ. "Sensitivity of glioma and fetal brain cell lines to natural killer cytolysis in a monolayer assay.." Journal Of Neuro-Oncology. Vol. 7, no. 2. (July 1989.): 145-152.

Zhang HF; Davis WB; Chen XS; Whisler RL; Cornwell DG. "Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact.." Journal Of Lipid Research. Vol. 30, no. 2. (February 1989.): 141-148.

Opremcak EM; Whisler RL; Dangel ME. "In vitro demonstration of human natural killing of keratocytes and corneal epithelium.." Annals Of Ophthalmology. Vol. 21, no. 3. (March 1989.): 96-102.

Zhang HF; Davis WB; Chen XS; Jones KH; Whisler RL; Cornwell DG. "Effects of oxidized low density lipoproteins on arachidonic acid metabolism in smooth muscle cells.." Journal Of Lipid Research. Vol. 31, no. 4. (April 1990.): 551-565.

Whisler RL, Newhouse YG, Donnerberg RL, Tobin CM. "Impairments in elevations of cytoplasmic free calcium and generation of inositol phosphates among stimulated T cells from elderly humans." Aging: Immunology and Infectious Disease. (January 1990.): -.

Whisler RL, Chen J-R, Newhouse YG. "Identification of age-related changes in the activation/proliferation of human B cells independent from T cell influences." Aging: Immunology and Infectious Disease. Vol. 2, no. 2. (January 1990.): 83-90.

Zhang H, Davis WB, Chen X, Whisler RL, Cornwell DG. "Paradoxical effects of vitamin E: oxidized lipoproteins, prostanoids, and the pathogenesis arthersclerosis." Free Radicals, Lipoproteins & Membrane Lipids. (January 1990.): 215-237.

Whisler RL; Williams JW Jr; Newhouse YG. "Human B cell proliferative responses during aging. Reduced RNA synthesis and DNA replication after signal transduction by surface immunoglobulins compared to B cell antigenic determinants CD20 and CD40.." Mechanisms Of Ageing And Development. Vol. 61, no. 2. (December 1991.): 209-222.

Whisler RL; Liu BQ; Newhouse YG; Walters JD; Breckenridge MB; Grants IS. "Signal transduction in human B cells during aging: alterations in stimulus-induced phosphorylations of tyrosine and serine/threonine substrates and in cytosolic calcium responsiveness.." Lymphokine And Cytokine Research. Vol. 10, no. 6. (December 1991.): 463-473.

Whisler RL; Newhouse YG; Chen JR. "Proliferative responses of B cells from elderly humans: abnormalities in early responsiveness are related to alterations in B cell activation molecules.." Lymphokine And Cytokine Research. Vol. 10, no. 1-2. (April 1991.): 1-6.

Opremcak EM; Cowans AB; Orosz CG; Adams PW; Whisler RL. "Enumeration of autoreactive helper T lymphocytes in uveitis.." Investigative Ophthalmology & Visual Science. Vol. 32, no. 9. (August 1991.): 2561-2567.

Myers RL; Whisler RL; Stephens RE; Sponseller CA; Livingston K; Spring PM; Yates AJ. "Sensitivity of human glioma and brain cells to natural killer cell lysis. Effects of serum concentration, epidermal growth factor, and time in culture.." Journal Of Neurosurgery. Vol. 76, no. 6. (June 1992.): 986-990.

Liu B, Cornwell DG, Whisler RL. "Age-related changes in DNA in human T cells: accelerated unwinding of double-strand DNA after oxidant stress and identification of DAN fragmentation resembling apoptosis." Aging: Immunology and Infectious Disease. Vol. 3, no. 3. (January 1992.): 101-116.

Whisler RL; Beiqing L; Grants IS; Newhouse YG. "Cyclic AMP modulation of human B cell proliferative responses: role of cAMP-dependent protein kinases in enhancing B cell responses to phorbol diesters and ionomycin.." Cellular Immunology. Vol. 142, no. 2. (July 1992.): 398-415.

Scarborough DA, Bisaccia E, Cornwell DG, Whisler RL, Liu Y, Panganamala R. "Adipose tissue metabolism: review, in vitro studies, and body fat distribution correlates." American Journal of Surgery. Vol. 9, no. 1. (January 1992.): 77-80.

Whisler RL; Liu B; Wu LC; Chen M. "Reduced activation of transcriptional factor AP-1 among peripheral blood T cells from elderly humans after PHA stimulation: restorative effect of phorbol diesters.." Cellular Immunology. Vol. 152, no. 1. (November 1993.): 96-109.

Whisler RL; Grants IS. "Age-related alterations in the activation and expression of phosphotyrosine kinases and protein kinase C (PKC) among human B cells.." Mechanisms Of Ageing And Development. Vol. 71, no. 1-2. (October 1993.): 31-46.

Zhang H; Downs EC; Lindsey JA; Davis WB; Whisler RL; Cornwell DG. "Interactions between the monocyte/macrophage and the vascular smooth muscle cell. Stimulation of mitogenesis by a soluble factor and of prostanoid synthesis by cell-cell contact.." Arteriosclerosis And Thrombosis: A Journal Of Vascular Biology / American Heart Association. Vol. 13, no. 2. (February 1993.): 220-230.

Whisler RL; Newhouse YG; Beiqing L; Karanfilov BK; Goyette MA; Hackshaw KV. "Regulation of protein kinase enzymatic activity in Jurkat T cells during oxidative stress uncoupled from protein tyrosine kinases: role of oxidative changes in protein kinase activation requirements and generation of second messengers.." Lymphokine And Cytokine Research. Vol. 13, no. 6. (December 1994.): 399-410.

Bailer RT; Lazo A; Harisdangkul V; Ehrlich GD; Gray LS; Whisler RL; Blakeslee JR. "Lack of evidence for human T cell lymphotrophic virus type I or II infection in patients with systemic lupus erythematosus or rheumatoid arthritis.." The Journal Of Rheumatology. Vol. 21, no. 12. (December 1994.): 2217-2224.

Whisler RL; Newhouse YG; Grants IS; Hackshaw KV. "Differential expression of the alpha- and beta-isoforms of protein kinase C in peripheral blood T and B cells from young and elderly adults.." Mechanisms Of Ageing And Development. Vol. 77, no. 3. (January 1995.): 197-211.

Whisler RL; Goyette MA; Grants IS; Newhouse YG. "Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells.." Archives Of Biochemistry And Biophysics. Vol. 319, no. 1. (May 1995.): 23-25.

Whisler RL; Newhouse YG; Bagenstose SE. "Age-related reductions in the activation of mitogen-activated protein kinases p44mapk/ERK1 and p42mapk/ERK2 in human T cells stimulated via ligation of the T cell receptor complex.." Cellular Immunology. Vol. 168, no. 2. (March 1996.): 201-210.

Ginn-Pease ME; Whisler RL. "Optimal NF kappa B mediated transcriptional responses in Jurkat T cells exposed to oxidative stress are dependent on intracellular glutathione and costimulatory signals.." Biochemical And Biophysical Research Communications. Vol. 226, no. 3. (September 1996.): 695-702.

Beiqing L; Chen M; Whisler RL. "Sublethal levels of oxidative stress stimulate transcriptional activation of c-jun and suppress IL-2 promoter activation in Jurkat T cells.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 157, no. 1. (July 1996.): 160-169.

Liu B; Hackshaw KV; Whisler RL. "Calcium signals and protein tyrosine kinases are required for the induction of c-jun in Jurkat cells stimulated by the T cell-receptor complex and oxidative signals.." Journal Of Interferon & Cytokine Research: The Official Journal Of The International Society For Interferon And Cytokine Research. Vol. 16, no. 1. (January 1996.): 77-90.

Whisler RL; Beiqing L; Chen M. "Age-related decreases in IL-2 production by human T cells are associated with impaired activation of nuclear transcriptional factors AP-1 and NF-AT.." Cellular Immunology. Vol. 169, no. 2. (May 1996.): 185-195.

Whisler RL; Chen M; Beiqing L; Carle KW. "Impaired induction of c-fos/c-jun genes and of transcriptional regulatory proteins binding distinct c-fos/c-jun promoter elements in activated human T cells during aging.." Cellular Immunology. Vol. 175, no. 1. (January 1997.): 41-50.

Liu B; Carle KW; Whisler RL. "Reductions in the activation of ERK and JNK are associated with decreased IL-2 production in T cells from elderly humans stimulated by the TCR/CD3 complex and costimulatory signals.." Cellular Immunology. Vol. 182, no. 2. (December 1997.): 79-88.

Whisler RL; Bagenstose SE; Newhouse YG; Carle KW. "Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex.." Mechanisms Of Ageing And Development. Vol. 98, no. 1. (October 1997.): 57-73.

Whisler RL; Karanfilov CI; Newhouse YG; Fox CC; Lakshmanan RR; Liu B. "Phosphorylation and coupling of zeta-chains to activated T-cell receptor (TCR)/CD3 complexes from peripheral blood T-cells of elderly humans.." Mechanisms Of Ageing And Development. Vol. 105, no. 1-2. (September 1998.): 115-135.

Ginn-Pease ME; Whisler RL. "Redox signals and NF-kappaB activation in T cells.." Free Radical Biology & Medicine. Vol. 25, no. 3. (August 1998.): 346-361.

VanAman SE; Whisler RL. "Differential expression of p53 tumor suppressor protein and IL-2 in activated T cells from elderly humans.." Journal Of Interferon & Cytokine Research: The Official Journal Of The International Society For Interferon And Cytokine Research. Vol. 18, no. 5. (May 1998.): 315-320.

Liu B; Whisler RL. "Transcriptional activation and redox regulation of the tumor necrosis factor-alpha promoter in human T cells: role of the CRE/kappa3 promoter region.." Journal Of Interferon & Cytokine Research: The Official Journal Of The International Society For Interferon And Cytokine Research. Vol. 18, no. 11. (November 1998.): 999-1007.

Karanfilov CI; Liu B; Fox CC; Lakshmanan RR; Whisler RL. "Age-related defects in Th1 and Th2 cytokine production by human T cells can be dissociated from altered frequencies of CD45RA+ and CD45RO+ T cell subsets.." Mechanisms Of Ageing And Development. Vol. 109, no. 2. (August 1999.): 97-112.

Whisler RL; Chen M; Liu B; Newhouse YG. "Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of zeta-chains and p59fyn/p56lck in human T cells.." Mechanisms Of Ageing And Development. Vol. 111, no. 1. (November 1999.): 49-66.

Ginn-Pease ME; Whisler RL. "Alterations in the expression of interleukin-2R subunits by activated T cells from elderly humans are uncoupled from aberrancies in G1/S progression.." Journal Of Interferon & Cytokine Research: The Official Journal Of The International Society For Interferon And Cytokine Research. Vol. 21, no. 7. (July 2001.): 515-521.

Whisler RL; Gray LS; Hackshaw KV. "Rheumatology, a clinical overview.." Clinics In Podiatric Medicine And Surgery. Vol. 19, no. 1. (January 2002.): 149-.