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Sonal Pannu, MD


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473 W 12th Ave, 201 DHLRI
Columbus, OH 43210

Phone: (614) 688-3698

Email: pannu.8@osu.edu

 

Current OSU Appointments

Assistant Professor-Clinical, Pulm,Allergy,Crit Care & Sleep

Physician, FGP-Pulm-Allrgy-CritCare-Sleep

 

Biographical

My career goal is to improve patient care and outcomes via translational research though my role as a physician investigator. I started working towards this aim during internal medicine residency, there I involved myself in observational research in critical care and was able to identify that as my future interest. My interest led to some of my initial publications as well acknowledgement of my research activities within the Institution and at regional conferences. Through fellowship at the Mayo Clinic, I got an opportunity to further explore my interest. Mechanical ventilation serves as the backbone for the critically ill patient. Understanding optimal oxygen management and improving survival and quality of life by preventing hyperoxia as well as hypoxia is critical. My interest, led to the revelation that oxygen titration was inadequately done and led to worsened pulmonary outcomes. This was then followed by a randomized study for which I was intramurally funded. The preliminary results of the trial are encouraging , and shows that a practice change can be initiated by setting a decision support for titration. In the same vein, I looked at patients with severe hypoxemia, trying to understand prognostic factors and effects of therapies to improve oxygenation. With the help of my team, we were able to create prediction model for mortality in severe hypoxemic respiratory failure, this was acknowledged and awarded the outcomes award in the society of critical care medicine in 2012. Since, we were not able to get clear answers about treatment strategies in refractory hypoxemia patients, we then sent out a national survey to critical care physicians about the use of therapies for severe and refractory hypoxemia, this effort was received intra mural funding.



I aim to continue working the in field of oxygen management. I believe, that the intensive care unit being a truly multidisciplinary environment, care of the patient can be truly impacted by involving all health care staff, including physicians, nurses and respiratory therapists. Using biomedical informatics based alerts to improve process of care and prevent iatrogenic injury, has shows to be beneficial in literature and I believe utilization of the same for oxygen management is beneficial. I aim to continue work in this filed with the goal of achieving federal funding for my career development and transforming into an independent researcher.

Certifications

2005 - present ECFMG: Educational Commission for Foreign Medical Graduates
2009 - present Board Certified Internal Medicine: American Board of Internal Medicine (ABIM)
2011 - present Board Certified Critical Care Medicine: American Board of Critical Care Medicine
2013 - present Doctor of Medicine: State Medical Board of Ohio
 

Conferences

Rachmale S, Kanna B, Torchon F, Basir R, Venkatram. "Packed RBC transfusion: Are We Following Evidence Based Medicine." In .. (January 2008). .-.

Rachmale S, Alejandro A, Shrivastava S, Loganathan R, Venkatram, S. "Utilization of Non-Invasive Positive Pressure Ventilation Compared to Invasive Mechanical Ventilation Among Patients with COPD in an Inner City Medical ICU: Our Leap Frog Experience over a 3-Year Period." In .. (September 2008). .-.

Lopez C, Rachmale S, Alejandro A, Kanna B, Loganathan R, Venkatram. "Outcomes of mechanically ventilated patients with status asthma- Does illicit substance use or obesity predict morbidity and mortality." In .. (September 2008). .-.

Rachmale S, Yong D, Grande J, Kennedy C, Mullon J, Kianoush K. "Efficacy of Educational Modalities for Shock State Management." In .. (December 2009). .-.

Rachmale S, Kennedy C. "Case Report on Herbal Hepatotoxicity Necessitating Orthotopic Liver Transplantation." In .. (December 2009). .-.

Rachmale S, G Li, Cartin-Ceba R, Ahmed A, Dhokarh R, Kashyap R, Thakur L, Gajic O. "Effect of Liberal Oxygenation Targets on Pulmonary Outcomes in ARDS." In .. (December 2009). .-.

Khokarh R, Li G, Rachmale S, Kashyap R, Gajic O, Cartin-Ceba R, Thakur S, Trillo-Alvarez A. "Outcome of Drug Induced Acute Lung Injury: A Population Based Study." In .. (December 2009). .-.

Rachmale S, G Li, Cartin-Ceba R, Ahmed A, Alsara A, Kashyap R, Wilson M, Gajic O. "Use of Rescue Therapies for ARDS Patients: Population-based study in Olmstead County, Minnesota." In .. (December 2010). .-.

Rachmale S; Moreno Franco P; Li G; Wilson G; Ding S; Alsara A; Ognjen G. "Predictors for Mortality in Patients with Refractory Hypoxemia." In .. (April 2011). .-.

Moreno Franco P; Rachmale S; Li G; Wilson G;Ding S; Alsara A; Ognjen G. "Rescue Therapies in Patients with Refractory Hypoxemia." In .. (April 2011). .-.

Rachmale S, MorenoFranco P, Wilson G, Li G, Gajic O. "Development and Validation of Severe Hypoxemia Related ICU Mortality Prognostic Model (SHRIMP) in 1000 Mechanically Ventilated Patients with Refractory Hypoxemia." In .. (January 2012). .-.

Pannu,Sonal; Holets,Steven; Li,Man; Marquez,Alberto; Kashyap,Rahul; Al-Qadi,Mazen,O; Wilson,Gregory; Gajic,Ognjen. "Titration of Inspired oxygen levels during mechanical ventilation through a respiratory therapist driven approach based on an electronic surveillance system (TOOLS)." In .. (December 2012). .-.

Marquez,Alberto; Li,Man; Holets,Steven; Kashyap,Rahul; Giri,Jyothsna; Gajic,Ognjen; Pannu,Sonal. "VALIDATION OF AN ELECTRONIC SURVEILLANCE SYSTEM WITH A DECISION SUPPORT TOOL FOR TITRATION OF INSPIRED OXYGEN LEVELS DURING MECHANICAL VENTILATION IN ADULTS." In CRITICAL CARE MEDICINE. (December 2012). U235-U236.

Kaur,Rupinder; Pannu,Sonal; Wilson,Gregory; Alhurani,Rabe; Vela,Myriam; Kilickaya,Oguz; Hubmayr,Rolf; Gajic,Ognjen; Kaufman,David. "INHALED NITRIC OXIDE LOWERS DEAD SPACE FRACTION IN ACUTE RESPIRATORY DISTRESS SYNDROME." In CRITICAL CARE MEDICINE. (December 2012). U120-U121.

Rachmale S; Moreno Franco P; Li G; Wilson G; Ding S; Alsara A; Ognjen G. "Rescue Therapies and Mortality in Patients with Refractory Hypoxemia." In .. (April 2012). .-.

 

Degrees

2003 M.D., Grant Medical College

2014 M.S., Mayo Clinic College of Medicine

 

Editorial Activities

2011 - present Respiratory Care
2014 - present Seminars in Respiratory and Critical Care Medicine
 

Honors

2007 - present Annual Hippocrates Resident Research Competition Award. Lincoln Medical Center.
2008 - present Annual Hippocrates Resident Research Competition Award. Lincoln Medical Center.
2009 - present Award of Excellence in Research. Annual Scientific Assembly 2009.
2011 - present Critical Care Meritorious Research Award. Critical Care Medicine.
2012 - present Epidemiology/Outcomes Specialty Award. 41st Critical Care Congress.
2012 - present Burgher Family Endowed Fellowship in Pulmonary and Critical Care. Burgher Family.
 

Journal Articles

Venkatram S, Rachmale S, Kanna B. "Study of device use adjusted rated in health care-associated infections after implementation of "bundles" in a closed-model medical intensive care unit." J Crit Care. Vol. 25, no. 1. (March 2010.): 174-.

Venkatram S, Rachmale S, Kanna B, Soni A. "Positive Pressure Ventilation Compared To Invasive Mechanical Ventilation Among Patients with COPD Exacerbation in an Inner City MICU-Predictors of NPPV Use." The Internet Journal of Pulmonary Medicine. Vol. 12, (July 2010.): 1-.

Li G, Rachmale S, Kojicic M, Shahjehan K, Malinchoc M, Kor DJ, Gajic O. "Incidence and transfusion risk factors for transfusion-associated circulatory overload among medical intensive care unit patients." Transfusion. Vol. 51, (February 2011.): 338-343.

Rachmale S, Li G, Gajic O. "Prevention of Acute Respiratory Distress Syndrome." Clinical Pulmonary Medicine. Vol. 18, (November 2011.): 300-304.

Rachmale S, Li G, Wilson G, Malinchoc M, Gajic O. "Practice of Excessive Inspired Oxygenation (Fio2) Supplementation and Effect on Pulmonary Outcomes in Mechanically Ventilated Patients with Acute Lung Injury." Respir Care. Vol. 11, (November 2012.): 1887-93.

Ahmed,Adil,H; Litell,John,M; Malinchoc,Michael; Kashyap,Rahul; Schiller,Henry,J; Pannu,Sonal,R; Singh,Balwinder; Li,Guangxi; Gajic,Ognjen. "The Role of Potentially Preventable Hospital Exposures in the Development of Acute Respiratory Distress Syndrome: A Population-Based Study." Critical Care Medicine. Vol. 42, no. 1. (January 2014.): 31-39.

Pannu SR, Hubmayr RD. "Safe Mechanical Ventilation in Patients without ARDS." Anesthesiologica. -.

 

Presentations

"Renal Failure in Severe Sepsis and Septic Shock: Does EGDT improve outcomes." Presented at American College of Chest Physicians, Philadelphia, PA. (October 2008)

"Neutroleptic Malignant Syndrome: A Case Report in a Patient with Parkinson's Disease." Presented at American College of Physicians Annual Scientific Meeting, Syracuse, NY. (October 2008)

"Packed RBC Transfusion: Are we following evidence based medicine." Presented at 37th Critical Care Congress, Society of Critical Care Medicne, Hawaii. (February 2008)

"Utilization of Non-Invasive Positive Pressure Ventilation Compared to Invasive Mechanical Ventilation Among Patients with COPD in an Inner City Medical ICU: Our Leap Frog Experience Over a 3-Year Period." Presented at ACCP CHEST Meeting, Philadelphia, PA. (October 2008)

"Case Report on Thyrotoxic Periodic Paralysis in a Young Hispanic Male." Presented at American College of Physicians, Internal Medicine, Philadelphia, PA. (January 2008)

"Pneumocystis Carinii Pneumonia in a Non-HIV Patient with Dermatomyositis." Presented at American College of Physicians Annual Scientific Meeting, Syracuse, NY. (October 2008)

"Outcomes of mechanically ventilated patients with status asthma- Does illicit substance use or obesity predict morbidity and mortality." Presented at ACCP CHEST Meeting, Philadelphia, PA. (October 2008)

"Decreasing Hospital Acquired Infection in an Inner City ICU Through a Standardized Team Approach." Presented at American Thoracic Society NY State Scientific Assembly, West Point, NY. (January 2009)

"Efficacy of Educational Modalities for Shock State Management. Does Simulation have an Edge?." Presented at 39th Critical Care Congress, Society of Critical Care Medicine Meeting, Miami Beach, FL. (January 2010)

"Case Report on Herbal Hepatotoxicity Necessitating Orthotopic Liver Transplantation." Presented at 39th Critical Care Congress, Society of Critical Care Medicine Meeting, Miami Beach, FL. (January 2010)

"Effect of Liberal Oxygenation Targets on Pulmonary Outcomes in ARDS." Presented at 39th Critical Care Congress, Society of Critical Care Medicine Meeting, Miami Beach, FL. (January 2010)

"Outcome of Drug Induced Acute Lung Injury: A Population Based Study." Presented at 39th Critical Care Congress, Society of Critical Care Medicine Meeting, Miami Beach, FL. (January 2010)

"Simulation-based Shock State Module improves skill for Bed-side Clinical Management in Medical Students." Presented at Innovations of Medical Education Conference, Pasadena, CA. (March 2010)

"Use of Rigid Bronchoscopy." Presented at 66th Annual Tri-State Thoracic Conference, Egg Harbor, WI. (September 2010)

"Use of Rescue Therapies for ARDS Patients: Population-based study in Olmstead County, Minnesota." Presented at 40th Critical Care Congress, Society of Critical Care Medicine Meeting, San Diego, CA. (January 2011)

"Predictors for Mortaility in Patients with Refractory Hypoxemia." Presented at American Thoracic Society International Conference, Denver, CO. (May 2011)

"Rescue Therapies in Patients with Refractory Hypoxemia." Presented at American Thoracic Society International Conference, Denver, CO. (May 2011)

"Esophageal Rupture Presenting as Asystole." Presented at American College of Chest Physicians CHEST Meeting, Honolulu, HI. (October 2011)

"Development and Validation of Severe Hypoxemia Related ICU Mortality Prognostic Model (SHRIMP) in 1000 Mechanically Ventilated Patients with Refractory Hypxemia." Presented at 41st Critical Care Congress, Houston, TX. (February 2012)

"Rescue Therapies and Mortality in Patients with Refractory Hypoxemia." Presented at American Thoracic Society International Conference, San Francisco, CA. (May 2012)

"Severe and Refractory Hypoxemic Respiratory Failure and Rescue Strategies: A National Survey of Critical Care Physicians." Presented at National Institutes of Health Meeting, Bethesda, MD. (November 2012)

"Glomus Tumour of the Trachea. A Case Report." Presented at American College of Chest Physicians Annual Scientific Meeting, San Francisco, CA. (April 2013)

"Titration of Inspired onygen levels during mechanical ventilation through a respiratory therapist driven approach based on an electronic surveillance system (TOOLS)." Presented at 42nd Critical Care Congress, San Juan, PR|PRI. (January 2013)

"Inhaled nitric oxide lowers dead space fraction in acute respiratory distress syndrome." Presented at 42nd Critical Care Congress, San Juan, PR|PRI. (January 2013)

"Validation of an electronic surveillance system with a decision support tool for titration of inspired oxygen levels during mechanical ventilatin in adults." Presented at 42nd Critical Care Congress, San Juan, PR|PRI. (January 2013)

 

Unpublished Works

Pannu SR, MorenoFranco P, Li G, Wilson, G, Gajic, O. Development and Validation of Severe Hypoxemia Associated Risk Prediction Model (SHARP) in 1000 Mechanically Ventilated Patients with Refractory Hypoxemia.