Naeem Ali, MD

Current OSU Appointments

Associate Professor-Clinical, Pulm,Allergy,Crit Care & Sleep

Physician, FGP-Pulm-Allrgy-CritCare-Sleep

Biographical

Over the course of my seven years at Ohio State University, I have the opportunity to leverage my professional activities to have an impact on the Critical Care Community locally, nationally and internationally. Beginning with my interest in reducing the complications that delay or prevent the recovery of critically ill patients, I have cultivated a clinical and research interest in preventing the complications that occur during the delivery of care to critically ill patients. My efforts over this time have been balanced between administrative, clinical, teaching and research efforts that have led to tangible advances in the understanding of how to best care for the critically ill. My clinical and administrative role has allowed me to oversee the daily operations of and provide clinical care in the Medical Intensive Care Unit of OSU Medical Center. My leadership has led to the development of a clinical database that has facilitated process improvement initiatives which have improved care to all patients in the health system requiring mechanical ventilation or sepsis treatment. This alignment between my clinical service and administrative responsibilities has facilitated my ability to not only improve the care of medical ICU patients, but those in all ICUs around the health system. In keeping with the theme of expanding the reach and impact of my work, I have led education, teaching and curricular development efforts that have focused on educating the entire team of healthcare professionals that must work together to deliver evidence-based critical care when and wherever it is needed. Beginning with education focused on physician trainees within the ICU, I have now moved my educational efforts to non-physician professionals. This interest in multidisciplinary education began with serving as an invited speaker at national pharmacy meeting (2003) and has progressed to developing a continuing education conference for physicians, respiratory therapists, nurses and the rest of the ICU team that in its first drew more than 230 attendees from around the state. Finally, my research interests have led to more than 20 publications in the areas of ICU organization, glucose regulation and ICU-acquired weakness. The importance of his work has been recognized in the lay press with a feature article in the New York Times about my observations on ICU-acquired weakness in early 2009. The details of this work were published in the most widely read Critical Care journal, The American Journal of Respiratory and Critical Care Medicine in 2008. In follow-up to this work, my leadership has been recognized by multiple invited international lectures on this syndrome and his recent appointment by the American Thoracic Society to lead an international consensus panel of clinical and research experts in ICU-acquired weakness. This initiative encompasses a multidisciplinary effort to define the clinical approach to these patients. Finally, my clinical and translational research attempting to understand the causes of ICUAW has led to promising collaborations that will explore the role of angiogenesis in the development of this morbid complication. In summary, I believe I have had an impact locally on all critically ill patients around the medical center, regionally on hundreds of practitioners working in ICUs around the state and internationally on the academic thought leaders studying the syndrome of ICU-acquired weakness.

Clinical Interest

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Clinical Interest

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Clinical Interest

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Clinical Interest

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Clinical Interest

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Continuing Education, Extension, and Other Courses Taught

Within the first several years in academic critical care, I recognized the importance of the multidisciplinary focus to clinical care. This clinical focus was in stark contrast to the general structure of clinical education. I was struck through active participation in continuing education conferences in Respiratory Therapy, Nursing and Medical Societies, that each of these disciplines only attempted to educate “their own”. This was likely due to a historical approach and the increasingly specific accreditation demands. In 2003, I gave my first lecture at the American Society of Health System Pharmacists in New Orleans, LA on the impact of computerized ordering systems on ICU care. Then in 2006, I gave a lecture at a statewide Respiratory Therapy conference (CCRC). The experience of these presentations gave me the insight of “spreading the message” of the principals that guide care in the ICU to non-MD professionals could have a great impact on the ability to deliver evidence-based practices to our patients in the critical care unit. I recognized there was an opportunity to start a regional conference that sought to educate the entire team of healthcare professionals on the important principles of patient care that needed widely disseminated. This resulted in my leading the development of the MATCH Conference (https://ccme.osu.edu/ConferenceDetail.aspx?ID=667) The MATCH Conference is dedicated to the mission of providing “state-of-the-art education in a multidiscipline format (team presentations) in a multidiscipline environment. RTs, RN and MDs can all receive continuing education credit. This educational environment is unique within critical care and is consistent with the national goals for the delivery of ICU patient care. In its first year, more than 230 persons from six different areas of healthcare attended. We plan to continue this conference annually with a goal of >350 attendees in 2010. From these goals, I have learned that my interests in this area is extending the reach of medical education to all of the disciplines that we collaborate with and rely upon to execute our plan of care. My plan is to expand on this avenue of multidisciplinary education as a primary focus in future years.

Creative Works

Developing a clinical laboratory: a clinical database to better understand care in the ICU With the advent of electronic information systems nationally and at OSU, there was significant hope that clinical data would become more readily available and thus better inform process improvement initiatives. However, soon after joining the faculty at OSU, it became apparent that these systems' underlying databases were not designed to support ready extraction of data for these purposes. They primarily served the needs of accurately maintaining a patient's medical record in perpetuity and support hospital financial reimbursement. As such, as I became involved in understanding ICU process of care, I became aware of the need to expedite the information transfer from these systems to improve care in our units. To fill a gap in our current resources, a small group of individuals met to discuss ongoing data collection needs to better understand ICU process of care. I led the portion of this group generated the needs for general measures of ICU care. This included generating an accurate list of ICU patients, their need for mechanical ventilation, the specific ventilator practices used and their receipt of daily quality practices like, sedation stops, ventilator liberation trials and other components of the ventilator bundle. After this list of variables was developed, I spent 6-8 months defining clinical documentation fields within the electronic medical record that represented these practices. Working with programmers within the Information Warehouse, we collaboratively designed the data and database workflows to populate the ICU Minimum Dataset. For the smaller list of variables not readily available electronically, I participated with our clinical trials office in the training of data collectors who acquired these important variables to complement and verify the automatic query results. I continue to supervise these data collectors to ensure the ongoing integrity of the database. As a result of this work, we are able to better understand the impact of our various ICU initiatives. Since 2004, we can demonstrate that our ventilator practices are objectively better, severity adjusted mortality for sepsis patients are improved and our compliance with quality practices have improved. Additionally, more recent hospital initiatives involving antibiotic ordering has resulted in an improved ability to rapidly administer antibiotics to our patients with sepsis. This database has dramatically changed our understanding of ICU process and practices. It has allowed us to better plan and initiate process improvement initiatives. A separate group, led by Jim O'Brien developed a similar database for sepsis patients within our ICU (termed the Sepsis Minimum Dataset). I collaborated with Dr O'Brien in its development and have had ongoing responsibility to maintain the database and ensure accuracy of the human and electronic processes that continue to populate the patient lists and data for the Db.

Published Works

The topics covered in a global overview of my work spans a direct line from my initial interests in the mechanisms of acute lung injury to my current interest in non-pulmonary organ failure in patients with sepsis. As an early fellow in critical care medicine, I was struck with the unique requirements of the ICU environment. As we were transitioning our ordering system from paper to a computer interface, I took the opportunity to propose, execute and publish my observations of the critical elements that led to successful implementation of these systems in the ICU. After these investigation performed, I left this area to enter into the laboratory to understand the basic mechanisms of acute lung injury (ALI), the most common cause of respiratory failure in the medical ICU. This research focused on TGF-beta regulation and while it took a while for this line of work to mature, it formed the nidus of research that led to my current funding for acute lung injury in severe sepsis. (K23 RR019544) As this research matured, I continued to pursue the clinical problems that influenced the development of ALI in ICU patients. The problem of glucose dysregulation was becoming more widely recognized. Significant research pointed to the fact that glucose dysregulation could lead to increased cellular stress and perhaps a greater propensity for ALI. As a result, I designed a pilot study to determine the role of hyperglycemia in patients at high-risk for severe sepsis. This retrospective analysis led to the publication of a report outlining the risk hyperglycemia appears to pose to patients with acute myeloid leukemia. This disease cohort was selected because of their propensity to develop severe sepsis and ALI (OR 30+ compared to non-leukemia). This report was published in 2007 and led to the main clinical study supported by my K23 research award. This study is now closed to enrollment and we are analyzing data. In the most recent phase of my research career, my interest was piqued by the connection between glucose dysregulation and the problem of critical illness polyneuropathy (also termed ICU-acquired weakness). This recently described clinical entity was known to occur more frequently than once suspected and to be associated with significant clinical morbidity. As a result, in 2005 we initiated a study across five academic medical centers that advanced our understanding of the impact of this disorder and was published in 2008. This nexus of weakness and glucose dysregulation now dominates my research program. This opened up opportunities to do multi-institutional interdisciplinary research. [eProtocol-Insulin LDS Hospital UT, voluntary extension of NIH Roadmap Contract “Reengineering Clinical Research in Critical Care.” (NO1-HC 45210, HHSN 268200425210C)] Additionally, I have been recently appointed the Chair of an International Consensus Conference to delineate definitions and standard assessments for this disorder of ICU-acquired weakness. This conferences work is progressing nicely and will be completed in the Fall of 2011.

Chapters in Books

Rami Khayat, Naeem Ali, Ulysses Magalang. "Monitoring Respiration in Sleep." In Principles of Sleep Medicine. -. January 2007.

Steven Kadiev, Naeem Ali. "Sleep in the Intensive Care Unit." In Sleep Medicine Clinics. Vol. 3 (4). Edited by Ulysses Magalang. -. Burlington, MA, US|USA: Elsevier, January 2008.

Naeem Ali, James Krinsley, Jean-Charles Preiser. "Glucose variability in critically ill patients." In Yearbook of Intensive Care and Emergency Medicine, 2009. Edited by Jean-Louis Vincent. TBD-. New York, NY, US|USA: Springer, January 2008.

Clinical Services

07/01/2003	Staff Physician in the medical ICU (OSUHS, Internal Medicine)
09/01/2003	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
12/01/2003	Staff Physician, Pulmonary Consultative Service (Ohio State University Hospitals, Main Campus, Internal Medicine)
01/01/2004	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
04/01/2004	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
06/01/2004	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
08/01/2004	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
11/01/2004	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
01/01/2005	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
01/01/2005	Staff Physician, Critical Care and Pulmonary consultative service (Ohio State University Hospital East, Internal Medicine)
03/01/2005	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
07/01/2005	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
08/01/2005	Staff Physician (Consultative Service)
10/01/2005	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
11/01/2005	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
02/01/2006	Staff Physician, Pulmonary and Critical Care consultation service (Ohio State University Hospital East, Internal Medicine)
07/01/2006	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
08/01/2005 - 08/01/2006	Staff Physician, Pulmonary Consultation Service (The Ohio State University Hospital, Main Campus, Internal Medicine)
08/01/2006	Staff Physician, OSU East Pulmonary and Critical Care consultation service (Ohio State University Hospital East, Internal Medicine)
01/01/2007	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
03/01/2007	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
04/01/2007	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
08/01/2007	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
10/01/2007	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
12/01/2007	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
04/01/2008	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
10/01/2008	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
03/01/2009	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
04/01/2009	Staff Physician, MICU (11th floor Rhodes Hall, University Hospital, Main Campus, Internal Medicine)
06/01/2009	Staff Physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
07/01/2009	Staff physician on the 8ICU (8th Floor Rhodes ICU OSU Hospital Main campus, Internal Medicine)
08/01/2009	Staff physician, MICU (11th floor Rhodes Hall, University Hospital Main Campus, Internal Medicine)
09/01/2009	Staff physician, 8ICU (8th floor Rhodes Hall, University Hospitals, Main Campus, Internal Medicine)
12/01/2009	Staff Physician, MICU (11th floor MICU, Rhodes Hall, Universoty Hospital Main campus, Internal Medicine)
01/01/2010	Staff Physician (8ICU, Medicine)
04/01/2010	Staff Physician (MICU)
11/01/2010	Staff Physician (MICU)
12/01/2010	Staff Physician (8ICU)
01/01/2011	Staff Physician (MICU)
04/01/2011	Staff Physician (MICU 40)
07/01/2011	Staff Phyician (MICU 90)
08/01/2011	Staff Physician (8ICU)
10/01/2011	Staff Physician (Risk)
11/01/2011	Staff Physician (8ICU)
04/01/2012	Staff Physician (8ICU)
06/01/2012	Staff Physician (MICU 40)

Journal Articles

Ali, Naeem, A; O'Brien, James; Hoffmann, Stephen. "Critical illness polyneuropathy." Critical care medicine. Vol. 33, no. 7. (July 2005.): 1674-5; author reply 1675.

O'Brien, James M Jr; Ali, Naeem, A; Abraham, Edward. "Year in review in Critical Care, 2004: sepsis and multi-organ failure.." Critical care (London, England). Vol. 9, no. 4. (August 2005.): 409-413.

Ali, Naeem, A; Mekhjian, Hagop, S; Kuehn, P Lynn; Bentley, Thomas, D; Kumar, Rajee; Ferketich, Amy, K; Hoffmann, Stephen P. "Specificity of computerized physician order entry has a significant effect on the efficiency of workflow for critically ill patients.." Critical care medicine. Vol. 33, no. 1. (March 2005.): 110-114.

Magro, Cynthia; Ali, Naeem, A; Williams, JoAnna, D; Allen, James, N; Ross, Patrick Jr. "Cytomegalovirus-associated pulmonary septal capillary injury sine inclusion body change: a distinctive cause of occult or macroscopic pulmonary hemorrhage in the immunocompetent host.." Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry. Vol. 13, no. 3. (September 2005.): 268-272.

O'Brien, James M Jr; Phillips, Gary, S; Ali, Naeem, A; Lucarelli, Maria; Marsh, Clay, B; Lemeshow, Stanley. "Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury.." Critical care medicine. Vol. 34, no. 3. (March 2006.): 738-744.

O'Brien, James M Jr; Ali, Naeem, A; Aberegg, Scott, K; Abraham, Edward. "Sepsis." The American Journal of Medicine. Vol. 120, no. 12. (December 2007.): 1012-1022.

O'Brien, James M Jr; Lu, Bo; Ali, Naeem, A; Martin, Greg, S; Aberegg, Scott, K; Marsh, Clay, B; Lemeshow, Stanley; Douglas, Ivor S. "Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult intensive care unit patients.." Critical care medicine. Vol. 35, no. 2. (February 2007.): 345-350.

Ali, Naeem, A; O'Brien, James M Jr; Blum, William; Byrd, John, C; Klisovic, Rebecca, B; Marcucci, Guido; Phillips, Gary; Marsh, Clay, B; Lemeshow, Stanley; Grever, Michael R. "Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality.." Cancer. Vol. 110, no. 1. (July 2007.): 96-102.

Judy M. Opakek, Naeem Ali, Clay B. Marsh. "Alveolar macrophages lack CCR2 expression and do not functionally respond to monocyte chemoattractant protein-1." Journal of Inflammation. no. 4. (September 2007.): 19-.

Naeem A. Ali, James M. O’Brien, Jr, Stephen P. Hoffmann, Gary Phillips, Allan Garland, James C.W. Finley, Khalid Almoosa, Rana Hejal, Karen M. Wolf, Stanley Lemeshow, Alfred F. Connors Jr, Clay B. Marsh. "Acquired weakness, handgrip strength and mortality in critically ill patients." American Journal of Respiratory and Critical Care Medicine. Vol. 178, no. 3. (August 2008.): 261-268.

Naeem A. Ali. "Moving toward preventive therapy in acute lung injury." Critical Care Medicine. Vol. 5, no. 36. (May 2008.): 1666-1667.

Ali, Naeem, A, O'Brien JM Jr, Dungan K, Phillips G, Marsh CB, Lemeshow S, Connors AF Jr, Preiser JC.. "Glucose variability and mortality in patients with sepsis." Critical Care Medicine. Vol. 8, no. 36. (August 2008.): 2316-2321.

James M. O'Brien, Jr, Naeem A. Ali, Edward Abraham. "Year in review 2007: Critical Care - multiple organ failure and sepsis." Critical Care. Vol. 5, no. 12. (October 2008.): 225-228.

Ali NA, Bickerstaff A, Licktenberger F, Flavahan N, Kaumaya P, Orosz CG, Marsh CB. "Latency Associated Peptide has In Vitro and In Vivo Biological Effects Independent of TGF-Beta." PLoS ONE. Vol. 4, no. 3. (April 2008.): e1914-.

O'Brien JM Jr, Aberegg SK, Ali NA, Diette GB, Lemeshow S. "Results from the national sepsis practice survey: predictions about mortality and morbidity and recommendations for limitation of care orders." Critical Care. Vol. 3, no. 13. (June 2009.): R96-.

Ali, Naeem, A, O'Brien Jr, James M, et al.. "Can Hand Dynamometry Serve as a Simple Test to Identify ICU-acquired Paresis?." Am J Respir Crit Care Med. Vol. 4, no. 179. (February 2009.): 329-330.

Robert D. Stevens, MD; Scott A. Marshall, MD; David R. Cornblath, MD; Ahmet Hoke, MD, PhD;Dale M. Needham, MD, PhD; Bernard de Jonghe, MD; Naeem A. Ali, MD; Tarek Sharshar, MD, PhD. "A framework for diagnosing and classifying intensive care unit acquiredweakness." Critical Care Medicine. Vol. Supplement, no. 37. (October 2009.): S299-S308.

Ali, Naeem, A. "How Strong is Weakness?." Critical care Medicine. Vol. 12, no. 37. (December 2009.): 3173-3174.

O'Brien JM Jr, Aberegg SK, Naeem A. Ali, Diette GB, Lemeshow S. "Results from the National Sepsis Practice Survey: Use of drotrecogin alpha (activated) and other therapeutic decisions." Journal of Critical care. no. epub ahead of print. (June 2010.): -.

Ali, Naeem, A. "Have we found the prevention for intensive care unit acquired paresis?." Critical care. Vol. 3, no. 14. (May 2010.): 160-.

Ezzie ME, Piper MG, Montague C, Newland CA, Opalek JM, Baran C, Naeem A. Ali, Brigstock D, Lawler J, Marsh CB.. "Thrombospondin-1 Deficient Mice Are Not Protected from Bleomycin-Induced Pulmonary Fibrosis." American Journal of Respiratory and Cellular Molecular Biology. no. epub ahead of print. (June 2010.): -.

Sara McMaken, Matthew E. Exline, Anasuya Sarkar, Melissa Piper, Clay Marsh Charles Cook and Naeem A. Ali. "Thrombospondin-1 contributes to mortality in murine sepsis through effects on innate immunity." PLoS ONE. Vol. 5, no. 6. (May 2011.): e19654-.

Naeem A. Ali, David Gutteridge, Sajid Shahul, William Checkley, Jonathan Sevransky, Greg S. Martin. "Critical illness outcome study: an observationalstudy of protocols and mortality in intensivecare units." Open Access Journal of Clinical Trials. Vol. 3, (September 2011.): 55-65.

Naeem A. Ali, Ted Warren, James M. O'Brien, Karen Wolf, Mitch Rashkin, Jeff Hammersley, Stephen Hoffmann, Gary Phillips and Allan Garland. "Continuity of Care in Intensive Care Units: A Cluster-Randomized Trial of Intensivist Staffing." American Journal of Respiratory and Critical Care Medicine. (January 2011.): -.

Brent P. Riscili, Tyler B. Anderson, Hallie C. Prescott, Matthew C. Exline, Madhuri M. Sopirala, Gary S. Phillips and Naeem A. Ali. "An Assessment of H1N1 Influenza-Associated Acute Respiratory Distress Syndrome Severity after Adjustment for Treatment Characteristics." PLoSONE. Vol. 6, no. 3. (March 2011.): e18166-.

James M. O'Brien Jr, Bo Lu, Naeem A. Ali, Deborah A. Levine, Scott K. Aberegg and Stanley Lemeshow. "Insurance type and sepsis-associated hospitalizations and sepsis-associated mortality among U.S. adults: a retrospective cohort study." Critical Care. Vol. 15, no. 3. (May 2011.): R130-.

Ali NA, Hammersley J, Hoffmann SP, O'Brien JM Jr, Phillips GS, Rashkin M, Warren E, Garland A. "Continuity of Care in Intensive Care Units: A Cluster-Randomized Trial of Intensivist Staffing." Am J Respir Crit Care Med.. Vol. 184, no. 7. (October 2011.): 803-8.

O'Brien JM Jr, Philips GS, Ali NA, Marsh CB. "The Association Between Body Mass Index, Processes of Care, and Outcomes from Mechanical Ventilation: A Prospective Cohort Study." Critical Care Medicine. Vol. 40, no. 5. (May 2012.): 1456-63.

Exline, MC, Ali, NA, Zikri, N, Mangino, JE, Torrence, K, Vermillion, B, St. Clair, J, Lustberg, M, Preeti, Pancholi, Sopirala, MM. "Beyond the Bundle- Journey of a Tertiary Care Medical Intensive Care Unit to Zero Central Line Associated Bloodstream Infections." Critical Care. Vol. 17, no. 2. (April 2013.): R41-.

Sopirala, MM, Haas, DM, Ali, NA, Mangino, JE, Pan, X, Turner, AN. "Effect of Fever on Hospital Presentation, Diagnosis, and Treatment in Patients with H1N1/09 Influenza." Journal of Hospital Medicine. Vol. 8, no. 1. (January 2013.): 20-24.

Reference Works

January 2002	Naeem A. Ali MD, J Allen, A Pope-Harman, P Ross, C Magro."Cytomegalovirus-associated Pulmonary Microangiopathy in the Normal Adult: An Emerging Cause of Alveolar Hemorrhage" Atlanta, GA.
January 2002	Naeem A. Ali MD, Frank Lichtenberger, Nicholas Flavahan, Clay Marsh."TGF-B Latency Associated Peptide (LAP) Induces Monocyte Chemotaxis" Atlanta, GA.
January 2003	Naeem A. Ali, Lynn Kuehn, Tom Bentley, Mary Beth Shirk, Hapgo Mekhjian, Stephen Hoffmann."Implementation of a computerized physician order entry system in a complex medical environment: elements of successful use in the ICU" San Antonio, TX.
January 2003	Naeem A. Ali MD, Frank Lichtenberger, Clay B. Marsh MD."TGF-B Latency-associated Peptide (LAP) Induced Monotype Chemotaxis is mediated through interactions with TSP-1" .
January 2003	Juan E. Morales, Naeem A. Ali, Nitin Bhatt, Stephen Hoffmann."Incidence and outcomes of HITT in patients with thrombocytopenia in a Medical ICU" San Antonio, TX.
January 2004	Naeem A. Ali, Lynn Kuehn, Tom Bentley, Mary Beth Shirk, Hagop Mekhjian, Stephen Hoffmann."Order Detail in CPOE has a significant impact on workflow in the ICU" .
January 2004	Naeem A. Ali MD, Frank Lichtenberger, Clay B. Marsh MD."TGF-B Latency-associated Peptide (LAP) cna independently act as an immunomodulatory molecule" .
January 2006	Brenda Hixon-Vermillion, Jennifer Leasure, Debbie Green, Christie Stegemiller, Naeem A. Ali."The effect of a bedside skin-care rounds on DPU rates in the ICU" .
January 2006	Tabitha West, Jennifer Leasure, James O'Brien Jr, Scott K. Aberegg, Naeem A. Ali."The effect of a bedside quality assurance auditor on improving compliance with VAP-prevention practices" .
May 2007	Naeem Ali, James O'Brien, Jean-Charles Preiser."Glucose variability and mortality in sepsis patients" .
May 2007	Naeem Ali, Frank Lichtenberger, Clay Marsh."Thrombospondin is important in determining survival after induction of a murine model of sepsis" .
January 2008	Lindsay Pell, Kari Mount, Naeem A. Ali."Experience with Dexmedetomidine in a Medical Intensive Care Unit" .
May 2008	Naeem Ali, Kathleen Dungan, James O'Brien, Jean-Charles Preiser."Early glucose variability is associated with subsequent hypoglycemia in sepsis patients" .
May 2008	Naeem Ali, James O'Brien, et al."Acquired weakness, handgrip strength and mortality in critically ill patients" .
May 2008	Michael Green, Leanne Strack, Clay Marsh, Naeem Ali."Clinical determinants of handgrip strength in critically ill patients" .
May 2008	J.M. O'Brien, M.D., M.Sc., M. Kearns, M.D., S.K. Aberegg, M.D., M., Naeem A. Ali, M.D., C.B. Marsh, M.D., S. Lemeshow, Ph.D."Factors Associated with Predicted Mortality of Septic Shock Patients: Results from the National Sepsis Practice Survey" . : A958
May 2008	J.M. O'Brien, B. Lu, Naeem A. Ali, S.K. Aberegg, C.B. Marsh, S. Lemeshow."Patients with Medicare and Medicaid Are at Increased Risk of Sepsis and Sepsis-Related Death" . : A639
May 2008	Eric Adkins, Matthew Exline, James O'Brien, Michael Sayre, Naeem A. Ali."Clinical Characteristics of In-Hospital Cardiac Arrest Patients Surviving to Hospital Discharge" .
May 2009	L.K. Strack, DO, J.M. O'Brien Jr, MD, S.P. Hoffmann, MD, G. Phillips, MAS, C.B. Marsh, MD, Naeem A. Ali, MD."Determinants of Handgrip Strength in Critically Ill Patients: A Secondary Analysis of the Findings from WIRE" . : A1585
May 2009	S. McMaken, MS, C.A. Newland, C.A. Schrader, BS, C.P. Baran, PhD, C.B. Marsh, MD, Naeem A. Ali, MD."Lack of Thrombospondin-1 in a Mouse Model of Sepsis Results in Increased Survival" . : A5730
May 2009	D.J. Wirtz, MD, H.C. Prescott, MD, Naeem A. Ali, MD, J.P. Parsons, MD, J.G. Mastronarde, MD."A Retrospective Analysis of Asthma Admissions at an Academic Medical Center in the Midwest" . : A1301
May 2009	B.P. Riscili, MD, T. Karsies, MD, S. McMaken, D. Dakhlallah, Naeem A. Ali MD, M. Hunter, PhD, C.B. Marsh, MD."Micro-RNA Expression in a Murine Model of Sepsis" . : A1165
March 2010	Madhuri Sopirala, Douglas Haas, Naeem A. Ali, Brent Riscili, Jeff Pan and Julie Mangino."Predictors of Disease Severity and Mortality in Hospitalized Patients with Novel H1N1 Influenza" .
May 2010	E.J. Adkins, MD, J.D. Huet, MD, S. Rahmanian, MD, B. Riscili, MD, V. Tarver, BS, J.W. McCallister, MD, J.G. Mastronarde, MD, Naeem A. Ali, MD."Clinical Factors Associated with Step-down Unit Request at ICU Discharge" . : A1658

Softwares

	Naeem Ali, James O'Brien, Stephen Hoffmann, John Mastronarde."The ICU Minimum Dataset" OSU Information Warehouse: Intranet
	Naeem Ali, James O'Brien, John Mastronarde, Matthew Exline, Beth Besecker."The ICU Sepsis Minimum dataset" OSU Information Warehouse

Presentations

"Catecholamine Cardiomyopathy." Presented at OSU Internal Medicine Grand Rounds, . (May 1999)

"Nocardiosis." Presented at OSU Internal Medicine Grand Rounds, . (April 2000)

"Finding A Fellowship in Internal Medicine." Presented at ACP_ASIM Ohio Chapter Scientific Meeting, . (October 2000)

"Acute Eosinophilic Pneumonia." Presented at Ohio Thoracic Society Case Conferrence, . (September 2000)

"Careers in Internal Medicine." Presented at AED Honors Pre-Medical Society, OSU Chapter, . (January 2001)

"Primary Pulmonary Hypertension presenting with Sudden Death, Diffuse Alveolar Hemorrhage." Presented at Ohio Thoracic Society Case Conferrence, . (October 2001)

"Computerized Physician Order Entry: Its not just about medication error reduction." Presented at Siemens Financial Health Executives Forum, . (May 2002)

"Common Problems of Internship." Presented at OSU Medical Therapeutics Course, . (February 2003)

"Computerized Physician Order Entry: Its not just about medication error reduction." Presented at American Society of Hospital Pharmacists Meeting, . (December 2003)

"Controversies in Pulmonary Embolism Diagnosis and Management." Presented at OSU Internal Medicine Grand Rounds, . (June 2003)

"Moderate and Deep Sedation." Presented at OSU Mednet, Columbus, OH, US|USA. (January 2004)

"Common Problems of Internship." Presented at Medical therapeutics, Columbus, OH, US|USA. (January 2004)

"Order Detail in CPOE has a significant impact on workflow in the ICU." Presented at Critical Care Grand Rounds, . (April 2004)

"Updateon Venous Thromboembolism Diagnosis." Presented at OSU MedNet, . (May 2005)

"Delirium in the ICU." Presented at OSU MedNet, . (August 2005)

"COPD Mimics." Presented at OSU Pulmonary and Critical Care CME course, Columbus, OH, US|USA. (January 2005)

"Common Problems of Internship." Presented at Medical Therapeutics, Columbus. (January 2005)

"Ventilator liberation: what’s the hurry?." Presented at Current Concepts in Respiratory Care, Columbus, OH, US|USA. (January 2006)

"Computerized Physician Order Entry: Its not just about medication error reduction." Presented at Critical Care Grand Rounds, Denver, CO, US|USA. (January 2006)

"Common Problems of Internship." Presented at Medical Therapeutics, . (January 2006)

"A User's guide to the Intensive Care Unit." Presented at Internal Medicine Grand Rounds, Columbus, OH, US|USA. (January 2006)

"Acquired neuromuscular disease in the ICU." Presented at Critical Care State of the Art update, Indianapolis, IN, US|USA. (January 2007)

"Advance Tools for Critical Care Delivery." Presented at American Thoracic Society Meeting 2007, San Francisco, CA, US|USA. (May 2007)

"Immediate outcomes from ICU-acquired weakness." Presented at Advances in Respiratory Care, Columbus, OH, US|USA. (March 2008)

"Sepsis: still misunderstood after all of these years." Presented at Marion General Hospital Grand Rounds, Marion, OH, US|USA. (January 2008)

"Interventions to reduce ICU-acquired weakness." Presented at Internal Medicine Grand Rounds, Columbus, OH. (January 2008)

"Immediate outcomes from ICU-acquired weakness." Presented at ICU outcomes, Columbus, OH, US|USA. (January 2008)

"Controversies in glucose management in Critically ill patients." Presented at Grand Rounds, Wyandot Memorial Hospital, Upper Sandusky, OH, US|USA. (January 2008)

"Immediate outcomes from ICU-acquired weakness." Presented at American Thoracic Society Meeting 2008, Toronto, CA. (May 2008)

"Clinical Determinants of Handgrip Strength in critically ill patients." Presented at ICU-physical therapy, North-American Conference, Toronto, ON. (May 2008)

"Assessing Strength in the ICU." Presented at ATS international Conference 2008, Toronto, ON. (May 2008)

"Current concepts in sepsis management." Presented at Grady Memorial Medical Grand Rounds, Marion, OH, US|USA. (October 2008)

"Advances in Sepsis knowledge and treatment." Presented at O'Blenness Hospital Grand Rounds, Athens, OH, US|USA. (October 2009)

"Sepsis Advances." Presented at Licking Memorial Hospital Grand Rounds, Zanesville, OH, US|USA. (August 2009)

"Consensus panel for clinical recemmendations on the assessment of ICU-acquired weakness." Presented at Consensus panel for clinical recemmendations on the assessment of ICU-acquired weakness, San Diego, CA, US|USA. (January 2009)

"Ventilator weaning in ICU-acquired Weakness." Presented at Current Concepts in Respiratory Care, Columbus, OH, US|USA. (March 2009)

"Sepsis Update." Presented at Southern Ohio Medical Center Medical Grand Rounds, Portsmouth, OH, US|USA. (May 2009)

"Consensus definitions of ICU-acquired weakness: clinical questions and background literature review." Presented at ATS Consensus conference on the clinical definition of ICU-acquired weakness, San Diego, CA, US|USA. (May 2009)

"Interventions to prevent ICU-acquired weakness." Presented at International Society of Intensive Care and Emergency Medicine Annual Meeting, Brussels, BE|BEL. (March 2010)

"Glucose variability in critically ill patients." Presented at International Society of Intensive Care and Emergency Medicine Annual Meeting, Brussels, BE|BEL. (March 2010)

"The utility of handgrip testing to predict outcomes in ICU patients." Presented at ICU-acquired weakness: A current state of the art, New Orleans, LA, US|USA. (May 2010)

"Consensus panel for clinical recemmendations on the assessment of ICU-acquired weakness." Presented at ATS Consensus conference on the definitions and assessments of ICU-acquired weakness, New Orleans, LA, US|USA. (May 2010)

"Consensus definitions of ICU-acquired weakness: focus areas and GRADE methodology." Presented at ATS Consensus conference on the definitions and assessments of ICU-acquired weakness, New Orleans, LA, US|USA. (May 2010)

"Comparison of Alternative Intensivist Staffing Schedules on Physician and Patient Outcomes in the Intensive Care Unit." Presented at Mini-Symposium/ A15-Intensive Care Unit Staffing/ ATS 2011, Denver, CO, US|USA. (May 2011)