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Clay B. Marsh, MD


Staff photo

McCampbell Hall North, 5th Floor
1581 Dodd Drive
Columbus, OH 43210

Phone: (614) 293-9309

Email: marsh.2@osu.edu

 

Current OSU Appointments

Vice Dean, ADM-Medicine Administration

Professor, SBS-Molec Vir, Imm & Med Gen

Professor, Veterinary Biosciences

Assoc Vp Health Sciences Rsch, Health Sciences Administration

Physician, FGP-Pulm-Allrgy-CritCare-Sleep

 

Biographical

Clay Marsh, MD is Executive Director of the Center for Personalized Health Care and Vice Dean and Senior Associate Vice President for Research at the College of Medicine. He is also Professor of Internal Medicine in the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine and is board certified in Pulmonary and Critical Care Medicine. He is the current director of the Center for Critical Care and Respiratory Medicine, one of six signature programs at OSU Medical Center, where he has implemented systems approaches to adherence to evidence-based guidelines to improve care delivery. He is cross-appointed in five basic science departments and graduate programs. Dr. Marsh is focused at understanding deep biology underlying human health and disease and has a 17 year history of consecutive funding from NIH and regularly serves on NIH study sections. He leads the efforts in Personalized Health Care at The Ohio State University, where he and the senior leadership are leading the effort in transforming health care delivery by creating pilot programs in wellness and chronic disease testing disruptive solutions that result in lower cost and higher quality/outcomes. Under his direction, OSU is a partner in the Coriell Institute’s Personalized Medicine Collaborative and led OSU’s efforts in partnering with the Institute for Systems Biology to form the P4 Medicine Institute. He has been listed in America’s Best Doctors© for each of the past 8 years. He has mentored over 50 MD, MD/PHD and PhD doctoral students, post-doctoral researchers and junior faculty. Dr Marsh is a member of the board of directors for the Personalized Medicine Coalition and on the executive board of the Utah Personalized Medicine Summit. He is the former director of the scientific board and past Chair of the Board of Directors of the Stanley Sarnoff Foundation for Cardiovascular Medicine and is on the National Advisory Board for the Pulmonary Bioinitiative for Lung Health and Disease with Battelle Memorial Institute and the Institute for Systems Biology and is an elected member of the American Society for Clinical Investigation. Dr. Marsh has published over 100 papers in peer-reviewed journals and maintains an active laboratory and clinical practice at Ohio State University.

Certifications

1985 - present Board Certification: National Board of Medical Examiners
1988 - present Board Certification: American Board of Internal Medicine
1989 - present Medical License: State Medical Board of Ohio
1993 - present Board Certification: American Board of Internal Medicine
1994 - present Board Certification: American Board of Internal Medicine
 

Chapters in Books

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Wewers MD, Gadek JE, Marsh CB. "Proinflammatory polypeptides." In The Lung: Scientific Foundations, 2nd Edition. Edited by Crystal RG and West JB. -. Lippencott-Raven, January 1996.

Marsh CB, Wewers MD. "Immunopathogenesis of sepsis." In Clinics in Chest Medicine. Edited by P. Dorinsky. 183-197. January 1996.

 

Degrees

1981 B.S., West Virginia University

1985 M.D., West Virginia University

 

Editorial Activities

1999 - 2007 Journal of Investigative Medicine
2007 Journal of Immunology, American Journal of Physiology, American Journal of Respiratory Cell and Molecular Biology
 

Honors

0 Appointment to the Scientific Board of the Stanley J. Sarnoff Endowment for Cardiovascular Sciences.
0 Alpha Omega Alpha.
1987 Veterans Administration Service Award.
1988 Outstanding Medical Resident Award. Department of Internal Medicine, College of Medicine.
1988 Medical Student Teaching Award.
1992 American Federation of Clinical Research Trainee Investigator Award.
1993 James V. Warren Research Award. Department of Internal Medicine, College of Medicine.
1997 - 1998 Teacher of the Year Award. Department of Internal Medicine, College of Medicine.
1998 - 1999 Faculty of the Year. Landacre Student Research Organization, College of Medicine.
1999 - 2002 Johnie Walker Murphy Career Investigator Award.
2000 Central Society for Clinical Research.
2001 Scientific Award. Stanley Sarnoff Foundation.
2001 Faculty Teaching Award. Department of Family Medicine, College of Medicine.
2001 Faculty Mentor Award. Davis Heart & Lung Research Institute.
2002 - 2004 Lung Biology and Pathology A. National Institues of Health.
2002 - 2004 Recipient. America’s Best Physicians Award.
2003 Presidential Award. American Lung Association of Ohio.
2003 - 2007 Study Section Member. National Institutes of Health, Lung Biology and Pathology A.
2004 Unverferth Research Award. Department of Internal Medicine, College of Medicine.
2004 Research Advocacy Board. American Thoracic Society.
2004 Elected Member. American Society for Clinical Investigation.
2005 Faculty Research Award. Landacre Student Research Organization, College of Medicine.
2005 America's Best Doctors.
2005 - 2006 Chair Elect, Scientific Board. Sarnoff Endowment for Cardiovascular Sciences.
2007 America's Best Doctors. U.S. News & World Report.
 

Journal Articles

Marsh, C B. "Polymyositis leading to diagnosis and resection of occult localized carcinoma of the cecum.." Southern medical journal. Vol. 71, no. 11. (January 1978.): 1441-3.

George D, Marsh CB, Leier CV. "The A Wave Liver." Clinical Cardiology. Vol. 11, (January 1988.): 349-350.

Herzyk, D, J; Allen, J, N; Marsh, C, B; Wewers, M D. "Macrophage and monocyte IL-1 beta regulation differs at multiple sites. Messenger RNA expression, translation, and post-translational processing.." Journal of immunology (Baltimore, Md. : 1950). Vol. 149, no. 9. (January 1992.): 3052-8.

Marsh, C, B; Mazzaferri, E L. "Shoulder and back pain with morning stiffness in an elderly woman.." Hospital practice (Office ed.). Vol. 29, no. 8. (January 1994.): 39-.

Marsh, C, B; Mazzaferri, E L. "Nephrotic syndrome, shoulder pain, and dyspnea in a persistent cougher.." Hospital practice (Office ed.). Vol. 29, no. 10. (January 1994.): 70-6, 79, 83 passim.

Marsh, C, B; Mazzaferri, E L. "Fever and diarrhea in a male college student.." Hospital practice (Office ed.). Vol. 29, no. 9. (January 1994.): 56-.

Marsh, C, B; Mazzaferri, E L. "Exertional dyspnea in a young woman.." Hospital practice (Office ed.). Vol. 29, no. 11. (January 1994.): 52-3.

Marsh, C, B; Mazzaferri, E L. "Epigastric pain and weight loss in a middle-aged man.." Hospital practice (Office ed.). Vol. 29, no. 12. (January 1994.): 45-.

Marsh, C, B; Wewers, M D. "Cytokine-induced interleukin-1 receptor antagonist release in mononuclear phagocytes.." American journal of respiratory cell and molecular biology. Vol. 10, no. 5. (January 1994.): 521-5.

Marsh, C, B; Trudeau, M, D; Weiland, J E. "Recurrent asthma despite corticosteroid therapy in a 35-year-old woman.." Chest. Vol. 105, no. 6. (January 1994.): 1855-7.

Marsh, C, B; Pope, H, A; Wewers, M D. "Fc gamma receptor cross-linking down-regulates IL-1 receptor antagonist and induces IL-1 beta in mononuclear phagocytes stimulated with endotoxin or Staphylococcus aureus.." Journal of immunology (Baltimore, Md. : 1950). Vol. 152, no. 9. (January 1994.): 4604-11.

Marsh, C, B; Moore, S, A; Pope, H, A; Wewers, M D. "IL-1ra suppresses endotoxin-induced IL-1 beta and TNF-alpha release from mononuclear phagocytes.." The American journal of physiology. Vol. 267, no. 1 Pt 1. (January 1994.): L39-45.

Allen, J, N; Moore, S, A; Pope-Harman, A, L; Marsh, C, B; Wewers, M D. "Immunosuppressive properties of surfactant and plasma on alveolar macrophages.." The Journal of laboratory and clinical medicine. Vol. 125, no. 3. (January 1995.): 356-69.

Marsh, C, B; Mazzaferri, E L. "Leg pain and numbness in an elderly man.." Hospital practice (Office ed.). Vol. 30, no. 1. (January 1995.): 59, 63-.

Marsh, C, B; Mazzaferri, E L. "Syncope in a middle-aged man at work.." Hospital practice (Office ed.). Vol. 30, no. 3. (January 1995.): 52-.

Marsh, C, B; Gadek, J, E; Kindt, G, C; Moore, S, A; Wewers, M D. "Monocyte Fc gamma receptor cross-linking induces IL-8 production.." Journal of immunology (Baltimore, Md. : 1950). Vol. 155, no. 6. (January 1995.): 3161-7.

Marsh, C, B; Wewers, M D. "The pathogenesis of sepsis. Factors that modulate the response to gram-negative bacterial infection.." Clinics in chest medicine. Vol. 17, no. 2. (January 1996.): 183-97.

Marsh, C, B; Anderson, C, L; Lowe, M, P; Wewers, M D. "Monocyte IL-8 release is induced by two independent Fc gamma R- mediated pathways.." Journal of immunology (Baltimore, Md. : 1950). Vol. 157, no. 6. (January 1996.): 2632-7.

Pue, C, A; Mortensen, R, F; Marsh, C, B; Pope, H, A; Wewers, M D. "Acute phase levels of C-reactive protein enhance IL-1 beta and IL-1ra production by human blood monocytes but inhibit IL-1 beta and IL-1ra production by alveolar macrophages.." Journal of immunology (Baltimore, Md. : 1950). Vol. 156, no. 4. (January 1996.): 1594-600.

Brown, E, A; Dare, H, A; Marsh, C, B; Wewers, M D. "The combination of endotoxin and dexamethasone induces type II interleukin 1 receptor (IL-1r II) in monocytes: a comparison to interleukin 1 beta (IL-1 beta) and interleukin 1 receptor antagonist (IL-1ra).." Cytokine. Vol. 8, no. 11. (January 1996.): 828-36.

Wewers, M, D; Marsh, C B. "Role of the antibody in the pathogenesis of transplant vascular sclerosis: a hypothesis.." Transplant immunology. Vol. 5, no. 4. (January 1997.): 283-8.

Ralston, D, R; Marsh, C, B; Lowe, M, P; Wewers, M D. "Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors.." The Journal of clinical investigation. Vol. 100, no. 6. (January 1997.): 1416-24.

Marsh, C, B; Wewers, M, D; Tan, L, C; Rovin, B H. "Fc(gamma) receptor cross-linking induces peripheral blood mononuclear cell monocyte chemoattractant protein-1 expression: role of lymphocyte Fc(gamma)RIII.." Journal of immunology (Baltimore, Md. : 1950). Vol. 158, no. 3. (January 1997.): 1078-84.

Brown EA, Pope HA, Marsh CB, Wewers MD. "LPS enhances type II receptor expression in dexamethosone treated macrophages: a comparison to IL-1 receptor antagonist." Cytokine. Vol. 8(11), (January 1997.): 828-836.

Knoell DL, Marsh CB. "Vocal Cord Dysfunction Presenting as Steroid-Dependent Asthma." Journal of Pharmacy Technology. Vol. 13, (January 1997.): 118-121.

Marsh, C, B; Lowe, M, P; Rovin, B, H; Parker, J, M; Liao, Z; Knoell, D, L; Wewers, M D. "Lymphocytes produce IL-1beta in response to Fcgamma receptor cross-linking: effects on parenchymal cell IL-8 release.." Journal of immunology (Baltimore, Md. : 1950). Vol. 160, no. 8. (January 1998.): 3942-8.

Knoell, D, L; Pierson, J, F; Marsh, C, B; Allen, J, N; Pathak, D S. "Measurement of outcomes in adults receiving pharmaceutical care in a comprehensive asthma outpatient clinic.." Pharmacotherapy. Vol. 18, no. 6. (January 1998.): 1365-74.

Kelley, T, W; Graham, M, M; Doseff, A, I; Pomerantz, R, W; Lau, S, M; Ostrowski, M, C; Franke, T, F; Marsh, C B. "Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.." The Journal of biological chemistry. Vol. 274, no. 37. (January 1999.): 26393-8.

Marsh, C, B; Pomerantz, R, P; Parker, J, M; Winnard, A, V; Mazzaferri, E L Jr; Moldovan, N; Kelley, T, W; Beck, E; Wewers, M D. "Regulation of monocyte survival in vitro by deposited IgG: role of macrophage colony-stimulating factor.." Journal of immunology (Baltimore, Md. : 1950). Vol. 162, no. 10. (January 1999.): 6217-25.

Kelley TW, Graham MM, Doseff A, Pomerantz RW, Lau SM, Ostrowski MC, Franke TW, Marsh CB. "M-CSF Promotes Cell Survivsl Through Akt/protein kinase B." Journla of Biological Chemistry. Vol. 274, (January 1999.): 26393-26398.

Rovin, B, H; Lu, L; Marsh, C B. "Lymphocytes induce monocyte chemoattractant protein-1 production by renal cells after Fc gamma receptor cross-linking: role of IL-1beta.." Journal of leukocyte biology. Vol. 69, no. 3. (January 2001.): 435-9.

Kelley TW, Graham MM, Marsh CB. "The role of ROS in monocyte survival and TGF-B production." Chest. Vol. 120(1), (January 2001.): 15S-16S.

Coulter, Kristin, R; Doseff, Andrea; Sweeney, Patricia; Wang, Yijie; Marsh, Clay, B; Wewers, Mark, D; Knoell, Daren L. "Opposing effect by cytokines on Fas-mediated apoptosis in A549 lung epithelial cells.." American journal of respiratory cell and molecular biology. Vol. 26, no. 1. (January 2002.): 58-66.

Tridandapani S, Wang Y, Marsh CB, Anderson CL. "SH2 Domain Containing Inositol Polyphosphate Phosphatase (SHIP) Regulates NFkB-Mediated Gene Transcription by Phagocytic Fcy Receptors in Human Myeloid Cells." Journal of Immunology. Vol. 169(8), (January 2002.): 4370-4378.

Tridandapani, Susheela; Wang, Yijie; Marsh, Clay, B; Anderson, Clark L. "Src homology 2 domain-containing inositol polyphosphate phosphatase regulates NF-kappa B-mediated gene transcription by phagocytic Fc gamma Rs in human myeloid cells.." Journal of immunology (Baltimore, Md. : 1950). Vol. 169, no. 8. (January 2002.): 4370-8.

Goyal, Anuj; Wang, Yijie; Graham, Mandy, M; Doseff, Andrea, I; Bhatt, Nitin, Y; Marsh, Clay B. "Monocyte survival factors induce Akt activation and suppress caspase-3.." American journal of respiratory cell and molecular biology. Vol. 26, no. 2. (January 2002.): 224-30.

Bhatt, Nitin, Y; Kelley, Todd, W; Khramtsov, Valery, V; Wang, Yijie; Lam, Gregory, K; Clanton, Thomas, L; Marsh, Clay B. "Macrophage-colony-stimulating factor-induced activation of extracellular-regulated kinase involves phosphatidylinositol 3-kinase and reactive oxygen species in human monocytes.." Journal of immunology (Baltimore, Md. : 1950). Vol. 169, no. 11. (January 2002.): 6427-34.

Fahy, Ruairi, J; Lichtenberger, Frank; McKeegan, Christine, B; Nuovo, Gerard, J; Marsh, Clay, B; Wewers, Mark D. "The acute respiratory distress syndrome: a role for transforming growth factor-beta 1.." American journal of respiratory cell and molecular biology. Vol. 28, no. 4. (January 2003.): 499-503.

Zeigler, Mandy, M; Doseff, Andrea, I; Galloway, Michelle, F; Opalek, Judy, M; Nowicki, Philip, T; Zweier, Jay, L; Sen, Chandan, K; Marsh, Clay B. "Presentation of nitric oxide regulates monocyte survival through effects on caspase-9 and caspase-3 activation.." The Journal of biological chemistry. Vol. 278, no. 15. (January 2003.): 12894-902.

Baran, Christopher, P; Tridandapani, Susheela; Helgason, Cheryl, D; Humphries, R Keith; Krystal, Gerald; Marsh, Clay B. "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity.." The Journal of biological chemistry. Vol. 278, no. 40. (January 2003.): 38628-36.

Tridandapani, Susheela; Wardrop, Richard; Baran, Christopher, P; Wang, Yijie; Opalek, Judy, M; Caligiuri, Michael, A; Marsh, Clay B. "TGF-beta 1 suppresses [correction of supresses] myeloid Fc gamma receptor function by regulating the expression and function of the common gamma-subunit.." Journal of immunology (Baltimore, Md. : 1950). Vol. 170, no. 9. (January 2003.): 4572-7.

Ganesan, Latha, P; Fang, Huiqing; Marsh, Clay, B; Tridandapani, Susheela. "The protein-tyrosine phosphatase SHP-1 associates with the phosphorylated immunoreceptor tyrosine-based activation motif of Fc gamma RIIa to modulate signaling events in myeloid cells.." The Journal of biological chemistry. Vol. 278, no. 37. (January 2003.): 35710-7.

Pengal, Ruma, A; Ganesan, Latha, P; Fang, Huiqing; Marsh, Clay, B; Anderson, Clark, L; Tridandapani, Susheela. "SHIP-2 inositol phosphatase is inducibly expressed in human monocytes and serves to regulate Fcgamma receptor-mediated signaling.." The Journal of biological chemistry. Vol. 278, no. 25. (January 2003.): 22657-63.

Eubank, Tim, D; Galloway, Michelle; Montague, Christine, M; Waldman, W James; Marsh, Clay B. "M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes.." Journal of immunology (Baltimore, Md. : 1950). Vol. 171, no. 5. (January 2003.): 2637-43.

Vasudevan, Sanjay, S; Lopes, Neuza H, M; Seshiah, Puvi, N; Wang, Tao; Marsh, Clay, B; Kereiakes, Dean, J; Dong, Chunming; Goldschmidt-Clermont, Pascal J. "Mac-1 and Fas activities are concurrently required for execution of smooth muscle cell death by M-CSF-stimulated macrophages.." Cardiovascular research. Vol. 59, no. 3. (January 2003.): 723-33.

Wang, Yijie; Keogh, Rosemary, J; Hunter, Melissa, G; Mitchell, Christina, A; Frey, Randall, S; Javaid, Kamran; Malik, Asrar, B; Schurmans, Stephane; Tridandapani, Susheela; Marsh, Clay B. "SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.." Journal of immunology (Baltimore, Md. : 1950). Vol. 173, no. 11. (January 2004.): 6820-30.

Fang, Huiqing; Pengal, Ruma, A; Cao, Xianhua; Ganesan, Latha, P; Wewers, Mark, D; Marsh, Clay, B; Tridandapani, Susheela. "Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP.." Journal of immunology (Baltimore, Md. : 1950). Vol. 173, no. 1. (January 2004.): 360-6.

Baran, Christopher, P; Zeigler, Mandy, M; Tridandapani, Susheela; Marsh, Clay B. "The role of ROS and RNS in regulating life and death of blood monocytes.." Current pharmaceutical design. Vol. 10, no. 8. (January 2004.): 855-66.

Cao, Xianhua; Wei, Guo; Fang, Huiqing; Guo, Jianping; Weinstein, Michael; Marsh, Clay, B; Ostrowski, Michael, C; Tridandapani, Susheela. "The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.." Journal of immunology (Baltimore, Md. : 1950). Vol. 172, no. 8. (January 2004.): 4851-7.

Jin, Ming; Opalek, Judy, M; Marsh, Clay, B; Wu, Haifeng M. "Proteome comparison of alveolar macrophages with monocytes reveals distinct protein characteristics.." American journal of respiratory cell and molecular biology. Vol. 31, no. 3. (January 2004.): 322-9.

Eubank, Tim, D; Roberts, Ryan; Galloway, Michelle; Wang, Yijie; Cohn, David, E; Marsh, Clay B. "GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.." Immunity. Vol. 21, no. 6. (January 2004.): 831-42.

Bao, Shenying; Wang, Yijie; Sweeney, Patricia; Chaudhuri, Alpana; Doseff, Andrea, I; Marsh, Clay, B; Knoell, Daren L. "Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells.." American journal of physiology. Lung cellular and molecular physiology. Vol. 288, no. 1. (January 2005.): L36-42.

Massullo, Pam; Druhan, Lawrence, J; Bunnell, Bruce, A; Hunter, Melissa, G; Robinson, John, M; Marsh, Clay, B; Avalos, Belinda R. "Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes.." Blood. Vol. 105, no. 9. (January 2005.): 3397-404.

Wu, Haifeng, M; Jin, Ming; Marsh, Clay B. "Toward functional proteomics of alveolar macrophages.." American journal of physiology. Lung cellular and molecular physiology. Vol. 288, no. 4. (January 2005.): L585-95.

Varadharaj, Saradhadevi; Steinhour, Emily; Hunter, Melissa, G; Watkins, Tonya; Baran, Christopher, P; Magalang, Ulysses; Kuppusamy, Periannan; Zweier, Jay, L; Marsh, Clay, B; Natarajan, Viswanathan; Parinandi, Narasimham L. "Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: regulation by MAP kinases.." Cellular signalling. Vol. 18, no. 9. (January 2006.): 1396-407.

O'Brien, James M Jr; Phillips, Gary, S; Ali, Naeem, A; Lucarelli, Maria; Marsh, Clay, B; Lemeshow, Stanley. "Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury.." Critical care medicine. Vol. 34, no. 3. (January 2006.): 738-44.

Montague, Christine, R; Hunter, Melissa, G; Gavrilin, Mikhail, A; Phillips, Gary, S; Goldschmidt-Clermont, Pascal, J; Marsh, Clay B. "Activation of estrogen receptor-alpha reduces aortic smooth muscle differentiation.." Circulation research. Vol. 99, no. 5. (January 2006.): 477-84.

Butchar, Jonathan, P; Parsa, Kishore V, L; Marsh, Clay, B; Tridandapani, Susheela. "Negative regulators of toll-like receptor 4-mediated macrophage inflammatory response.." Current pharmaceutical design. Vol. 12, no. 32. (January 2006.): 4143-53.

Lichtenberger F, Frambach G, Montague CM, Marsh CB. "NAC and DTT promote TGF-beta1 monomer formation: demonstrationof competitive binding." The Journal of Inflammation. Vol. 3, (January 2006.): 7-.

Jin M, Diaz PT, Bourgeois T, Eng C, Marsh CB, Wu H. "Two-dimensional get proteome reference map of blood monocytes." Proteome Science. Vol. 1, (January 2006.): 4-16.

Yang, Eric, V; Sood, Anil, K; Chen, Min; Li, Yang; Eubank, Tim, D; Marsh, Clay, B; Jewell, Scott; Flavahan, Nicholas, A; Morrison, Carl; Yeh, Peir-En; Lemeshow, Stanley; Glaser, Ronald. "Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.." Cancer research. Vol. 66, no. 21. (January 2006.): 10357-64.

Magalang, Ulysses, J; Rajappan, Ramya; Hunter, Melissa, G; Kutala, Vijay, K; Kuppusamy, Periannan; Wewers, Mark, D; Marsh, Clay, B; Parinandi, Narasimham L. "Adiponectin inhibits superoxide generation by human neutrophils.." Antioxidants & redox signaling. Vol. 8, no. 11-12. (January 2006.): 2179-86.

Bhatt, Nitin; Baran, Christopher, P; Allen, James; Magro, Cynthia; Marsh, Clay B. "Promising pharmacologic innovations in treating pulmonary fibrosis.." Current opinion in pharmacology. Vol. 6, no. 3. (January 2006.): 284-92.

Magro, Cynthia, M; Waldman, W James; Knight, Deborah, A; Allen, James, N; Nadasdy, Tibor; Frambach, Gwyn, E; Ross, Patrick; Marsh, Clay B. "Idiopathic pulmonary fibrosis related to endothelial injury and antiendothelial cell antibodies.." Human immunology. Vol. 67, no. 4-5. (January 2006.): 284-97.

Ai, Jing; Maturu, Amita; Johnson, Wesley; Wang, Yijie; Marsh, Clay, B; Tridandapani, Susheela. "The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1.." Blood. Vol. 107, no. 2. (January 2006.): 813-20.

Ai J, Maturu A, Johnson W, Wang Y, Marsh CB, S Tridandapani. "The inositol phosphatase SHIP-2 regulates FcyR-mediated phagocytosis in murine macrophages independently of SHIP-1." Blood. Vol. 107(2), (January 2006.): 813-20.

Wang, Yijie; Zeigler, Mandy, M; Lam, Gregory, K; Hunter, Melissa, G; Eubank, Tim, D; Khramtsov, Valery, V; Tridandapani, Susheela; Sen, Chandan, K; Marsh, Clay B. "The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival.." American journal of respiratory cell and molecular biology. Vol. 36, no. 1. (January 2007.): 68-77.

O'Brien, James M Jr; Lu, Bo; Ali, Naeem, A; Martin, Greg, S; Aberegg, Scott, K; Marsh, Clay, B; Lemeshow, Stanley; Douglas, Ivor S. "Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult intensive care unit patients.." Critical care medicine. Vol. 35, no. 2. (January 2007.): 345-50.

Opakek JM, Ali NA, Marsh CB. "MCP-1 is a selective cheomattractant for blood monocytes - SUBMITTED." (January 2007.): -.

Mo X, guttridge D, Hunter MG, Marsh CB. "MEK/Erk is critical in M-CSF-induced NF.....IN PREPARATION." (January 2007.): -.

Fulci G, Dmitrieva N, Gianni D, Fontana E, Lu Y, Kaufman C, Kaur B, Lawler S. Lee R, Marsh C, Brat D, vanRooijen N, Rachamimov A, Hockberg F, Weissleder R, Martuza R, Chiocca EA. "Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses - ACCEPTED." Cancer Research. (January 2007.): -.

Lichtenberg F, Marsh CB. "Surfactant activates latent TGF-B: potential role in human lung disease - IN PREPARATION." (January 2007.): -.

Hunter MG, Iltchev D, Marsh CBA. "A soluble factor released by THP-1 monocytic cells in response to PMA and GM-CSF-stimulated monocytes influences cellular differentiation - IN PREPARATION." (January 2007.): -.

Hagele, Thomas, J; Mazerik, Jessica, N; Gregory, Anita; Kaufman, Bruce; Magalang, Ulysses; Kuppusamy, M Lakshmi; Marsh, Clay, B; Kuppusamy, Periannan; Parinandi, Narasimham L. "Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress.." International journal of toxicology. Vol. 26, no. 1. (January 2007.): 57-69.

Baran CP, Opalek JM, McMaken S, Newland CA, O'Brien Jr JM, Hunter MG, Bringardner BD, Monick MM, Brigstock DR, Stromberg PC, Hunninghade GW, Marsh CB. "Important roles for M-CSF, CCL2 and mononuclear phagocytes in the pathogenesis of pulmonary fibrosis." Am J Respir Crit Care Medicine - Epub ahead of print. Vol. 176, no. 1. (July 2007.): 78-89.

O'Brien Jr JM, West T, Ali N, Smith R, Leasure J, Hoffmann S, Marsh C. "The clinical Assessment Nurse (CAN) Program Improves Adherence to Recommended Critical Care Practices - SUBMITTED." (January 2007.): -.

Ali N, Lichtenberger F, Bickerstaff A, Flavahan N, Orosz CG, Marsh CB. "LAP is Biologically Active and Regulates Inflammation via Interactions with Thrombospondin-1 and CD36 - REVISED Manuscript." (January 2007.): -.

 

Presentations

"Apoptosis: Good News or Bad?." Presented at Ohio State University - Internal Medicine Grand Rounds, . (January 1998)

"Update on Pulmonary Thromboembolic Disease." Presented at Pulmonary & Critical Care Review Course, . (February 1998)

"Update on new practives in the treatment of patients with asthma." Presented at Ohio State University East - Internal Medicine Grand Rounds, . (January 1999)

"Monocyte survival and human diseases: the next Akt.." Presented at Ohio State University - Internal Medicine Grand Rounds, . (January 1999)

"Update on Interstitial Lung Disease." Presented at Pulmonary & Critical Care Review Course, . (February 1999)

"Update on idiopathis pulmonary fibrosis." Presented at Ohio State University - Internal Medicine Grand Rounds, . (July 2000)

"Monocyte survival in heart and lung disease: too much of a good thing." Presented at Ohio State University - Internal Medicine Grand Rounds, . (May 2000)

"Life and death of the monocyte and impact on human disease." Presented at Ohio State University, Landacre Dinner Presentation, . (September 2000)

"Update on Pulmonary Fibrosis." Presented at OSU Pulmonary and Critical Care CME Course, . (February 2000)

"Update on community-acquired pneumonias." Presented at OSU Pulmonary and Critical Care Review Course, . (February 2000)

"The biochemical details of monocyte survival and differentiation: Roles in health and disease." Presented at Molecular Virology, Immunology and Human Genetics Seminar, . (August 2000)

"Academic Medicine: road to the future." Presented at Ohio State University - Internal Medicine Grand Rounds, . (August 2000)

"Life, Death and Differentiation of Monocytes." Presented at Ohio State University, Immunology Conference, . (October 2000)

"Details of intracellular mechanisms of monocyte survival and differentiation." Presented at Ohio State University, Department of Physiology and Cellular Biology, . (October 2000)

"Life and death decisions of monocytes - implications for cancer and inflammation." Presented at Molecular Therapeutics Group, . (March 2001)

"Discussant unknown case of SLE/anti-phospholipid." Presented at Ohio State University - Internal Medicine Grand Rounds, . (November 2001)

"Update on Asthma." Presented at Medical Therapeutics 2001, . (March 2001)

"Regulation of monocyte survival by nitric oxide." Presented at Davis Heart and Lung Research Institute, . (March 2001)

"the rold of monocytes in regulating fibrosis in the lung: implications for treatment of IPF." Presented at Ohio State University, Veterinary Biosciences Seminar Series, . (September 2001)

"Pulmonary Fibrosis: The Clinic Meets the Lab." Presented at Ohio State University - Internal Medicine Grand Rounds, . (September 2001)

"Update on Pulmonary Embolism." Presented at OSU Pulmonary and Critical Care CME Course, . (February 2002)

"Update on Asthma." Presented at Medical Therapeutics 2002, . (March 2002)

"International Wound Healing and Oxygen Treatment, The Clinic Meets the Lab." Presented at Ohio State University - Internal Medicine Grand Rounds, . (September 2002)

"New paradigms for the activation of TGF-B." Presented at Immunology Conference, . (October 2002)

"IGBP Featured Research Talk: The role of SHIP in the regulation of monocyte activation." Presented at Ohio State University, . (October 2002)

"Update on Asthma." Presented at Medical Therapeutics 2003, . (March 2003)

"Update on Pulmonary Embolus." Presented at Pulmonary & Critical Care Medicine Update 2003, . (February 2003)

"New paradigms in pulmonary fibrosis." Presented at Davis Heart and Lung Research Institute Conference, . (July 2004)

"The role of M-CSF in human health and disease." Presented at Pathology Grand Rounds, . (March 2005)

"M-CSF as a modulator of lung injury and repair." Presented at IGBP Seminar Series, . (March 2005)

"Pearls in writing NIH grants." Presented at Davis Heart and Lung Research Institute Review Course, . (November 2005)

"Adaptive immunity and immunological memory." Presented at Department of Molecular Virology, Immunolgy and Human Genetics, . (February 2005)

"How to get a K grant." Presented at Davis Heart and Lung Research Institute Review Course, . (March 2006)

"Sepsis." Presented at Ohio State University, Klassen Research Day, . (June 2006)

"Location, Location, Location: The Role of the Environment in Macrophage Function." Presented at Davis Heart and Lung Research Institute Retreat, . (April 2007)