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Virginia A. Folcik Nivar, PhD.
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Jonathan Butchar, PhD.
Carmen Cantemir, PhD.
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Virginia A. Folcik Nivar, PhD.
Mikhail Gavrilin, PhD.
Leni Moldovan, PhD.
Anasuya Sarkar, PhD.

Home > Directory > Research Scientists > Virginia A. Folcik Nivar, PhD.

 

Virginia A. Folcik Nivar, Ph.D.

Research Scientist

 

201 Davis Heart & Lung Research Institute

473 West 12th Avenue

Columbus, OH 43210

(614) 366-1332

Education:
2005 B.S.  Computer Science and Engineering, Magna Cum Laude, Ohio State Univ.
1993 Ph.D.  Regulatory Biology, Summa Cum Laude, Cleveland State Univ.
1988 B.S.  Biology, Medical Technology, Magna Cum Laude, Cleveland State Univ.


Post Doctoral Positions:

1993-1996  Postdoctoral Fellow, Dept. of Cell Biology, Lerner Research Institute
 of the Cleveland Clinic Foundation, Cleveland, OH
1996-1998  Postdoctoral Fellow, Dept. of Neurosciences, Lerner Research Institute
 of the Cleveland Clinic Foundation, Cleveland, OH
2000-2005  Student, OSU, Columbus, OH
2002-2005  Student Programmer, Transplant Surgery, OSUMC, Columbus, OH
2005-2006  Research Scientist, P.I., Transplant Surgery, OSUMC, Columbus, OH
2007-Present  Research Scientist, P.I., Internal Medicine, PACCS, OSUMC, Columbus, OH


Research Interests:
Immunology of atherosclerosis, mechanisms of lipid oxidation in atherosclerosis;
 mechanisms of disease pathology in multiple sclerosis; computer modeling
 (agent-based modeling) of the immune system and other complex systems;
 using agent-based modeling to study mechanisms of interstitial lung disease.


Grant Awards:
1993  One year fellowship grant from the American Heart Association, Northeast Ohio Affiliate.
1994  Three year National Research Service Award from the National Heart, Lung and Blood
 Institute of the National Institutes of Health.
2006  Ohio State University, Technology Education Learning Research, Research on Research,
 Student-Faculty ePartenership Grant (Student:  Christina Sass)
 http://digitalunion.osu.edu/r2/summer06/sass/
2009  Award Number R21HL093675-01 from the National Heart, Lung and Blood Institute of the
 National Institutes of Health, issued under the ARRA of 2009.  Title:  Agent-Based Modeling
 to Reveal Mechanisms of Idiopathic Interstitial Lung Disease.


Publications:
Folcik, V.A.
and M.K. Cathcart, 1992.  Assessment of 5-lipoxygenase involvement in human
 monocyte-mediated LDL oxidation.  J. Lipid Res.  34:69-79.
Folcik, V.A. and M.K. Cathcart, 1994.  Predominance of esterified hydroperoxy-linoleic acid
 in human monocyte-oxidized LDL.  J. Lipid Res.  35:1570-1582.
Folcik, V.A., R.A. Nivar-Aristy, L. Krajewski, and M.K. Cathcart, 1995.  Lipoxygenase
 contributes to the oxidation of lipids in human atherosclerotic plaques.
 J. Clin. Invest.  96:504-510.
Folcik, V.A., R. Aamir and M.K. Cathcart. 1997.  Cytokine modulation of LDL oxidation
 by activated human monocytes.  Arterioscler. Thromb. Vasc. Biol.  17:1954-1961.
Sorensen, T.L., Tani, M., Jensen, J., Pierce, V., Lucchinetti, C., Folcik, V.A., Qin, S.,
 Sellebjerg, F., Strieter, R., Frederiksen, J., Ransohoff, R.M.  1999.  Expression of specific
 chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients.
 J. Clin. Invest.  97(1-2):119-128.
Folcik, V.A., T. Smith, S. O’Bryant, J.A. Kawczak, B. Zhu, J. Bradshaw, H. Sakurai, A. Kajiwara,
 J.M. Staddon, A. Glabinski, A.L. Chernosky, M. Tani, J.M. Johnson, V.K. Tuohy, L.L. Rubin,
 and R.M. Ransohoff.  1999.  Treatment with BBB022A or Rolipram stabilizes the blood-brain barrier
 in experimental autoimmune encephalomyelitis:  An additional mechanism for the effect of type IV
 phosphodiesterase inhibitors.  J. Neuroimmunology.  97:119-128.
Cathcart, M.K. and Folcik, V.A.  2000.  Lipoxygenases and atherosclerosis:  Protection versus
 pathogenesis.  Free Radical Biology and Medicine.  28(12):1726-1734.
Folcik, V.A., An, G.C. and Orosz, C.G.  2007  The Basic Immune Simulator:  An agent-based model
 to study the interactions between innate and adaptive immunity.
 Theoretical Biology and Medical Modelling.  4:39.


Abstracts and Presentations:

Charles G. Orosz and Virginia A. Folcik.  2004.  Simulating the Complexity of the Immune Response.
 http://mbi.osu.edu/2003/ws5abstracts.html
Virginia A. Folcik and Charles G. Orosz.  2004.  The Immune System as a Complex Adaptive System:
 A RePast Simulation of the Anti-Viral Immune Response.
 http://cscs.umich.edu/swarmfest04/Program/Abstracts/abstracts.html#FolcikV
Virginia A. Folcik and Charles G. Orosz.  2006.  An Agent-Based Model Demonstrates that the Immune
 System Behaves Like a Complex System and a Scale-Free Network.
 http://www.nd.edu/~swarm06/Schedule/schedule.html
Virginia A. Folcik, Gerard Nuovo, Samir N. Ghadiali, James N. Allen and Clay B. Marsh.  2009.
 Using Agent-Based Modeling to Study Interstitial Lung Disease.
 http://www.swarm.org/index.php/Using_Agent-Based_Modeling_to_Study_Interstitial_Lung_Disease

 

 


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