DesJardin LE, Kaufman TM, Potts B, Kutzbach B, Yi H, Schlesinger LS. M. tuberculosis-infected human macrophages exhibit enhanced cellular adhesion with increased expression of LFA-1 and ICAM-1 and reduced expression and/or function of complement receptors, FcgRII and the mannose receptor Microbiology 148:3161-3171, 2002.
Olakanmi O, Schlesinger LS, Ahmed A, Britigan BE. Intraphagosomal Mycobacterium tuberculosis acquires iron from both extracellular transferrin and intracellular iron pools: impact of interferon-g and hemochromatosis J Biol Chem 277:49727-49734,2002.
Brown RM, Cruz O, Brennan M, Gennaro M, Schlesinger L, Yasir A, Skeiky W, Hoft DF. Lipoarabinomannan-reactive human secretory immunoglobulin a responses induced by mucosal bacille calmette-guerin vaccination. J. Infect. Dis., 187:513-517, 2003.
Olakanmi O, Schlesinger L S, Ahmed A, Britigan BE. The nature of extracellular iron influences iron acquisition by Mycobacterium tuberculosis residing within human macrophages. Infect. Immun.72:2022-2028, 2004.
Ferguson JS, Weis JJ, Martin JL, Schlesinger L S. Complement protein C3 binding to Mycobacterium tuberculosis is initiated by the classical pathway in human bronchoalveolar lavage fluid. Infect. Immun. 72:2564-2573, 2004.
Brown RM, Cruz O, Brennan M, Gennaro M, Schlesinger L, Yasir A, Skeiky W, Hoft DF. Lipoarabinomannan-reactive human secretory immunoglobulin a responses induced by mucosal bacille calmette-guerin vaccination. J. Infect. Dis., 187:513-517, 2003.
Crowther JE, Kutala, VK, Kuppusamy, P, Ferguson, JS, Beharka, AA, Zweier, JL, McCormack, FX, Schlesinger L S. Pulmonary Surfactant Protein A inhibits macrophage reactive intermediate production in response to stimuli by reducing NADPH oxidase activity J. Immunol., 172:6866-6874, 2004
"Tuberculosis: The Microbe-Host Interface." Schlesinger L S, DesJardin L, Co-Editors, Horizon Scientific Press, U.K. 2004.52. Phagocytosis and Toll-like Receptors in Tuberculosis, Invited Contributor. In: Tuberculosis 2nd Edition, William M. Rom, and Garay S.M., eds, Lippincott, Williams, and Wilkins, 203-214, 2004.
Olakanmi O, Schlesinger LS, Ahmed A, Britigan BE. The nature of extracellular iron influences iron acquisition by Mycobacterium tuberculosis residing within human macrophages. Infect. Immun. 72:2022-2028, 2004.
Ferguson JS, Weis JJ, Martin JL, Schlesinger LS. Complement protein C3 binding to Mycobacterium tuberculosis is initiated by the classical pathway in human bronchoalveolar lavage fluid. Infect. Immun. 72:2564-2573, 2004.
Crowther JE, Kutala VK, Kuppusamy P, Ferguson JS, Beharka AA, Zweier JL, McCormack FX, Schlesinger LS. Pulmonary Surfactant Protein A inhibits macrophage reactive intermediate production in response to stimuli by reducing NADPH oxidase activity. J. Immunol. 172:6866-6874, 2004.
Beharka AA, Crowther JE, McCormack FX, Denning G, Lees J, Tibesar E, Schlesinger LS. Pulmonary Surfactant Protein A activates a PI3 Kinase / calcium signal transduction pathway in human macrophages: participation in the up-regulation of mannose receptor activity. J. Immunol. 175: 2227-2236, 2005
Kang PB, Azad AK, Torrelles JB, Kaufman TM, Beharka A, Tibesar E, Schlesinger LS. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis J Exp. Med. 202:987-999, 2005.
McCarthy TR, Torrelles JB, MacFarlane A, Katawczik M, Kutzbach B, Clegg S, DesJardin LE, Goldberg JB, Schlesinger LS. Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in M. smegmatis and mycobacterial association with Human Macrophages. Mol. Micro. 58:774-790, 2005
Crowther JE and Schlesinger LS. Defining the phagocytic pathway for Surfactant Protein A in human macrophages: binding, clathrin-dependent Uptake, and trafficking through the endolysosomal pathway. Am J Physiol. 290:L334-L342, 2006.
Hall-Stoodley L, Watts G, Crowther JE, Balagopal A, Torrelles JB, Robison-Cox J, Bargatze RF, Harmsen AG, Crouch EC, Schlesinger LS. Mycobacterium tuberculosis binding to human surfactant proteins A and D, Fibronectin and small airway epithelial cells under shear conditions. Infect. Immun. 74:3587-3596, 2006.
Torrelles JB, Azad AK, Schlesinger LS. Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors. J. Immunol. 177:1805-1816, 2006.
Parsa KVL, Ganesan LP, Rajaram MVS, Gavrilin MA, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S. Macrophage pro-inflammatory response to Francisella novicida infection is regulated by the SH2 domain-containing inositol 5’ phosphatase SHIP. PLOS Pathogens 2:0681-0690, 2006.
Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS. Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages. Infect. Immun. 74: 5114-5125, 2006.
Ferguson JS, Martin JL, Azad AK, McCarthy TR, Kang PB, Voelker DR, Crouch EC, and Schlesinger LS. Surfactant Protein D Increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infect. Immun. 74:7005-7009, 2006.
Olakanmi O, Schlesinger LS, and Britigan BE. Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages. J Leuko Bio 81:195-204, 2007.
Mohaptra NP, Balagopal A, Soni S, Schlesinger LS, Gunn JS. AcpA is a Francisella Acid Phosphatase that affects Intramacrophage Survival and Virulence. Infect. Immun. 75: 390-396, 2007.
Young JD, Balagopal A, Reddy NS, Schlesinger LS. Pulmonary infections caused by non-tuberculous mycobacteria: An update on epidemiology, diagnosis, and treatment. J. Resp. Dis 28: 7-18, 2007.
Butchar JP, Rajaram MVS, Ganesan LP, Parsa KVL, Clay CD, Schlesinger LS, Tridandapani S. Francisella tularensis induces Interleukin-23 production in human monocytes. J. Immunol. 178:4445-4454, 2007.
Sow FB, Florence WC, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP. Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis. J Leuko Bio. 82:934-945, 2007.
Torrelles JB, Azad AK, Henning LH, Carlson TK, Schlesinger LS. Role of C-type lectins in mycobacterial infections (in press, Current Drug Targets).
Valdivia-Arenas MA, Amer A, Henning LN, Wewers MD, Schlesinger LS. Lung infections and innate host defense (in press, Drug Discovery Today).
