Abul K. Azad, PhD

E-mail: Abul.Azad@osumc.edu

Recent Publications

Sweet, L., Azad, A.K., Schlesinger. L.S. and Schorey, J.S. (2008). Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids. Infection and Immunity (in revision).

Azad, A.K., Torrelles, J.B. and Schlesinger, L.S. (2008). Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for both phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells. Journal of leukocyte Biology 84:1594-603.

Henning, L.N., Azad, A.K., Parsa, K.V.L., Crowther, J.E., Tridandapani, S. and Schlesinger L.S. (2008). Pulmonary surfactant protein-A regulates Toll-like receptor expression and activity in human macrophages. Journal of Immunology 180:7847 58.

Torrelles, J.B., Azad, A.K., Henning, L., Carlson, T. and Schlesinger, L.S. (2008). Role of C-type lectins in mycobacterial infections. Current Drug Targets 9: 102 112. (Review)

Schlesinger, L.S., Azad, A.K., Torrelles, J.B., Roberts, E., Vergne, I. and Deretic, V. (2008). “Determinants of phagocytosis, phagosome biogenesis and autophagy for Mycobacterium tuberculosis”. In Handbook of Tuberculosis: Immunology and Cell Biology. Kaufmann and Britton (eds.). WILEY-VCH Verlag GmbH & Co. Pages 1-22. (Book Chapter)

Ferguson, J.S., Martin, J.L., Azad, A.K., McCarthy, T.R., Kang, P.B., Voelker, D.R., Crouch, E.C. and Schlesinger, L.S. (2006). Surfactant protein D increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infection and Immunity 74: 7005-7009.

Torrelles, J.B., Azad, A.K. and Schlesinger, L.S. (2006). Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors. Journal of Immunolgy 177: 1805-1816.

Kang, P.B., *Azad, A.K., Torrelles, J.B., Kaufman, T.M., Beharka, A., Tibesar, E., DesJardin, L.E. and Schlesinger, L.S. (2005). The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. Journal of Experimental Medicine 202: 987-999. (* Co-first author)

Azad, A.K., Sirakova, T.D., Fernandes, N. and Kolattukudy, P.E. (1997). Gene knockout reveals a novel gene cluster for the synthesis of a class of cell-wall lipids unique to pathogenic mycobacteria. Journal of Biological Chemistry 272: 16741-16745.

Kolattukudy, P.E., Fernandes, N., Azad, A.K., Fitzmaurice, A.M. and Sirakova, T.D. (1997). Biochemistry and molecular genetics of cell wall lipid biosynthesis in mycobacteria (MicroReview). Molecular Microbiology 24: 263-270.

Azad, A.K., Sirakova, T.D., Rogers, L.M. and Kolattukudy, P.E. (1996). Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides. Proceedings of the National Academy of Sciences, U.S.A. 93: 4787-4792.