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Michael Grever, MD


Staff photo

395 W 12th Ave
Columbus, OH 43210

Phone: (614) 293-8724

Email: grever.1@osu.edu

 

Current OSU Appointments

Chair, Internal Medicine

Associate Dean, ADM-Medicine Administration

Professor, SBS-Pharmacology

Physician, FGP-Internal Medicine

 

Books

In vitro prostate cancer drug screen. Adenine Press {a}, January 1994.

In vivo drug screening applications of Hiv-infected human cells cultivated in hollow fibers. American Society for Microbiology (ASM) {a}, January 1995.

Pharmacology of cancer chemotherapy: Cancer drug discovery and development. Lippincott-Raven Publishers {a}, January 1997.

 

Chapters in Books

Grever, MR. "New cytotoxic anticancer agents." In Recent Advances in Clinical Therapeutics. Edited by Yetiv JZ, Bianchine JR. 85-95. New York, NY, US|USA: Grune & Stratton, Inc, January 1983.

Trewyn RW, Elliott MS, Glaser R, Grever MR. "Alterations in tRNA metabolism as markers of neoplastic transformation." In Bichemical and Biological Markers of Neoplastic Transformation. 263-275. New York, NY, US|USA: Plenum PUblishing Corp, January 1983.

Coleman MS, Grever MR. "Exploiting biochemical differences in leukemia." In Purine Catabolism in Man IV. Edited by Bebruyn C, Simmonds, HA, Muller M. 315-320. New York, NY, US|USA: Plenum Press Inc, January 1984.

Grever MR. "Investigational chemotherapy of chronic lymphocitic leukemia." In Chronic Lymphocytic Leukemia: Recent Progress and Future Direction. Edited by Gale, RP and Rai KR. 399-409. New York, NY, US|USA: Alan R. Liss, Inc, January 1987.

MCCaffrey R, Rai KR, Nadler LM, Grever MR. "Chronic lymphocytic leukemia." In Hematology 1989 Educational Program. -. Washington, DC, US|USA: American Society of Hematology, January 1989.

Grever MR, Malspeis L. "The importance of understanding the biochemical pharmacology of new agents prior to initiating multiagent chemotherapy programs." In Cancer Chemotherapy: Challenges for the Future. Vol. 5. Edited by Kimura K, Yamada K, Carter SK, and Griswold DP. 21-28. Tokyo, JP|JPN: Excerpta Medica, January 1990.

Cragg GM, Boyd MR, Cardellina JH II, Grever MR, Schepartz S, Snader KM Suffness M. "The search for new pharmaceutical crops: drug discovery and development at the National Cancer Institute, Proceedings Second National Symposium on New Crops." In New Crops. Edited by Janick J, Simon JE. 167-167. New York, NY, US|USA: John Wiley & Sons, January 1993.

Grever MR, Malspeis L. "The discovery and development of new anti-leukemic drugs." In Hematology/Oncology Clinics of North America: Advances in the Management of Acute Leukemia. Vol. 7. Edited by Bloomfield CD and Herzig GP. 233-254. Philadelpha, PA, US|USA: WB Saunders, January 1993.

Grever MR, Chabner BA. "Cancer drug discovery and development." In Cancer Principles & Practic of Oncology. 4th ed. Edited by DeVita VT Jr, Hellman S, and Rosenberg SA. 328-340. Philadelphia, PA, US|USA: JB Lippincott, January 1993.

Grever MR, Grieshaber CK. "Toxicology by organ system." In Cancer Medicine. 3rd ed. Edited by Holland E, Bast R Jr, Kufe D Morton D, Weichselbaum R. 683-697. Philadelphia, PA, US|USA: Lea and Fibiger, January 1993.

Cragg GM, Boyd MR, cardellina JH II, Grever MR, Schepartz SA, Snader KM, Suffness M:. "Role of plants in the National Cancer Institute Drug Discovery and Development Program." In ACS Symposium Series #534: Human Medicinal Agents from Plants. Edited by Kinghorn AD and Balandrin MR. 80-95. Washington, DC, US|USA: American Chemical Society, January 1993.

Cragg GM, boyd MR, Grever MR, Schepartz SA. "Policies for international collaboration and compensation in drug discovery and development at the United States National Cancer Institute. The NCI Letter of Intent." In Intellectual Property Rights for Indigenous Peoples: Source Book. 83-98. Oklahoma City, OK, US|USA: Society for Applied Anthropology, January 1994.

Cragg GM, Boyd MR, Grever MR, Mays, Newman DJ, Schepartz SA. "Natural Product Drug Discovery and Development at the National Cancer Symposium: Policies for International Collaboration and Compensation." In Proceedings of International Symposium on Intellectual Property Rights. Vol. 48. Edited by Adams RP, Miller JS, Goldenberg EM, Adams JE. 221-232. Jefferson City, MO: Missouri Botanical Garden, January 1994.

Chabner B, Winstein J, Paull K, Grever MR. "Cell line-based screening for anticancer drugs." In Cancer Treatment: an Update. Edited by Banzet P, Holland JF, Khayat D, Weil M. 10-16. Neu-Isenburg, DE|DEU: Springer-Verlag, January 1994.

Grever MR. "Cancer Drug Screening." In Principles of Antineoplastic Drug Development and Pharmacology. Edited by Schilsky, Milano, Rattain. 1-14. New York, NY, US|USA: Dekker, January 1996.

Cheson BD, Grever MR. "Clinical Development of 2-Deoxycoformycin." In Nucleoside Analogs in Cancer Therapy. Edited by Cheson, Keating, Plunkett. 95-112. New York, NY, US|USA: Dekker, January 1997.

Chabner B, Grever MR. "Cancer Drug Discovery and Development." In Cancer: Principles and Practice of Oncology. Edited by DeVita, VT Jr, Hellman S, and Rosenberg SA. 385-393. Philadelphia, PA, US|USA: JB Lippincott, January 1997.

Grever MR, Grieshaber CK. "Chapter 59: Toxicology by Organ System." In Cancer Medicine. 4th ed. Edited by Holland JF, Frei E, Bast R, Kufe D, Morton D, Weischselbaum R. 891-906. Philadelphia, PA, US|USA: Lea and Fibiger, January 1997.

Grever MR. "Management of Chronic Myeloid Leukemia." In ASCO Educational Book. -. Alexandria, VA, US|USA: American Society of Clinical Oncology, January 1998.

Grever MR, Kraut EH. "Advances in Blood Disorders Series: Hairy Cell Leukemia." In Past and Present Role of Pentostatin in Hairy Cell Leukemia. 151-161. London: Harwood Academic Publishers, January 2000.

Chu E, Grever MR, Chabner BA. "Cancer Drug Development: Identification and Screening of New Agents." In Cancer Principles & Practice of Oncology. 6th ed. Edited by DeVita T Jr, Hellman S and Rosenberg SA. 345-356. Philadelphia, PA, US|USA: JB Lippincott, January 2001.

Grever MR, Gewirtz AS, Byrd JC. "Chronic Lymphocytic Leukemia." In Clinical Hematology. Edited by Young NS, Gerson SL, High KA. 447-459. Mosby Elsevier, January 2006.

Grever MR. "Acute Lymphoblastic Leukemia." In Pocket Medicine / Internal Medicine, Version 2.0. -. January 2006.

Byrd JC, Awan F, LIn TS, Grever MR. "New Therapies in Chronic Lymphocytic Leukemia." In Chronic Lymphocytic Leukemia. Edited by O'Brien S and Gribben JG. -. New York, NY, US|USA: Informa Healthcare, January 2007.

Grever MR, Andritsos LA, Lozanski G. "Chronic Lymphoid Leukemias." In Clinical Oncology. Edited by Abeloff et al. 2293-2308. Maryland Heights, MO, US|USA: Elsevier Inc, January 2008.

 

Degrees

1967 B.S., University of Pittsburgh

1971 M.D., University of Pittsburgh

 

Editorial Activities

2009 - present The European Journal of Clinical and Medical Oncology
 

Honors

1989 Award for Meritorious Service as Chairman of the Leukemia Committee of the Southwest Oncology Group.
1994 NCI Letter of Appreciation from the Director.
1994 Accepted into the Senior Executive Service of the U.S. Government.
1999 La Medaille de la Ville de Paris for work and accomplishments in the treatment of Chronic Lymphocytic Leukemia.
2003 AAAS Fellow.
2005 America's Best Doctors.
2005 David Workman Memorial Achievement Award for Advances in "Difficult to Treat Malignancies". Samuel Waxman Cancer Research Foundation.
2006 10/19/06 Awarded 2006 Chancellor's Legacy Laureate Award. Presented by Chancellor Mark A. Nordenberg.
2008 Distinguished Alumnus Award. Department of Chemistry.
2009 - 2010 Best Doctors in America. U.S. News & World Report.
2010 Member. Alpha Omega Alpha Honor Medical Society, Ohio Chapter.
2010 Elected Member of Association of American Physicians.
2012 The Hench Award. College of Medicine.
2012 University Distinguished Scholar Award. Office of Research.
 

Journal Articles

Neary, J, T; Meneely, R, L; Grever, M, R; Diven, W F. "The interactions between biogenic amines and pyridoxal, pyridoxal phosphate, and pyridoxal kinase.." Archives of biochemistry and biophysics. Vol. 151, no. 1. (January 1972.): 42-7.

Koller, C, A; Mitchell, B, S; Grever, M, R; Mejias, E; Malspeis, L; Metz, E N. "Treatment of acute lymphoblastic leukemia with 2'-deoxycoformycin: clinical and biochemical consequences of adenosine deaminase inhibition.." Cancer treatment reports. Vol. 63, no. 11-12. (January 1979.): 1949-52.

Grever, M, R; Thompson, V, N; Balcerzak, S, P; Sagone, A L Jr. "The effect of oxidant stress on human lymphocyte cytotoxicity.." Blood. Vol. 56, no. 2. (January 1980.): 284-8.

Grever, M, R; Siaw, M, F; Jacob, W, F; Neidhart, J, A; Miser, J, S; Coleman, M, S; Hutton, J, J; Balcerzak, S P. "The biochemical and clinical consequences of 2'-deoxycoformycin in refractory lymphoproliferative malignancy.." Blood. Vol. 57, no. 3. (January 1981.): 406-17.

COLEMAN M, S; GREVER M R. "Exploiting Biochemical Differences In Leukemia." Journal of Clinical Chemistry and Clinical Biochemistry. Vol. 20, no. 6. (January 1982.): 360-.

GREVER M, R; FISHER J, A; O'DORISIO M, S; O'DORISIO T, M; BALCERZAK S P. "Bone Marrow Adenosine Deaminase Activity In Leukemia." Clinical Research. Vol. 30, no. 2. (January 1982.): 418A-.

Gray, D, P; Grever, M, R; Siaw, M, F; Coleman, M, S; Balcerzak, S P. "2'-deoxycoformycin (DCF) and 9-beta-D-arabinofuranosyladenine (Ara-A) in the treatment of refractory acute myelocytic leukemia.." Cancer treatment reports. Vol. 66, no. 2. (January 1982.): 253-7.

GRAY D, P; GREVER M R. "Effect Of 2' Deoxy Coformycin And Deoxy Adenosine On Macrophage Phagocytosis." Clinical Research. Vol. 30, no. 2. (January 1982.): 349A-.

GRAY D, P; COLEMAN M, S; SIAW M F, E; RINEHART J, J; O'DORISIO M, S; GREVER M R. "Macrophage Biochemical Abnormalities And Impaired Phagocytosis Associated With 2' Deoxy Coformycin And Deoxy Adenosine Culture." Clinical Research. Vol. 30, no. 4. (January 1982.): 735A-.

BISACCIA E, P; GREVER M, R; SCARBOROUGH D, A; NEIDHART J A. "Correlation Of Adenosine Deaminase Inhibition And Clinical Response To 2' Deoxy Coformycin In Cutaneous T Cell Lymphoma." Clinical Research. Vol. 30, no. 2. (January 1982.): 577A-.

Balcerzak, S, P; Grever, M, R; Sing, D, E; Bishop, J, N; Segal, M L. "Preliminary studies of continuous extracorporeal carbamylation in the treatment of sickle cell anemia.." The Journal of laboratory and clinical medicine. Vol. 100, no. 3. (January 1982.): 345-55.

COLEMAN M, S; GREVER M. "Enzymes Inhibitors And Leukemia Lymphoma." Journal of Cellular Biochemistry Supplement. no. 6. (January 1983.): 380-.

Heldman, D, A; Grever, M, R; Trewyn, R W. "Differential excretion of modified nucleosides in adult acute leukemia.." Blood. Vol. 61, no. 2. (January 1983.): 291-6.

Heldman, D, A; Grever, M, R; Speicher, C, E; Trewyn, R W. "Urinary excretion of modified nucleosides in chronic myelogenous leukemia.." The Journal of laboratory and clinical medicine. Vol. 101, no. 5. (January 1983.): 783-92.

Heldman, D, A; Grever, M, R; Miser, J, S; Trewyn, R W. "Relationship of urinary excretion of modified nucleosides to disease status in childhood acute lymphoblastic leukemia.." Journal of the National Cancer Institute. Vol. 71, no. 2. (January 1983.): 269-73.

Grever, M, R; Siaw, M, F; Coleman, M, S; Whisler, R, L; Balcerzak, S P. "Inhibition of K and NK lymphocyte cytotoxicity by an inhibitor of adenosine deaminase and deoxyadenosine.." J Immunol. Vol. 130, no. 1. (January 1983.): 365-9.

Grever, M, R; Coleman, M, S; Balcerzak, S P. "Adenosine deaminase and terminal deoxynucleotidyl transferase: biochemical markers in the management of chronic myelogenous leukemia.." Cancer research. Vol. 43, no. 3. (January 1983.): 1442-5.

Grever, M, R; Bisaccia, E; Scarborough, D, A; Metz, E, N; Neidhart, J A. "An investigation of 2'-deoxycoformycin in the treatment of cutaneous T-cell lymphoma.." Blood. Vol. 61, no. 2. (January 1983.): 279-82.

Klein, J, P; Klotz, J, H; Grever, M R. "A biological marker model for predicting disease transitions.." Biometrics. Vol. 40, no. 4. (January 1984.): 927-36.

Coleman, M, S; Grever, M R. "Exploiting biochemical differences in leukemia.." Advances in experimental medicine and biology. Vol. 165 Pt B, (January 1984.): 315-20.

Neidhart, J, A; Derocher, D; Grever, M, R; Kraut, E, H; Malspeis, L. "Phase I trial of teroxirone.." Cancer treatment reports. Vol. 68, no. 9. (January 1984.): 1115-9.

LEIBY J, M; KRAUT E, H; METZ E, N; NEIDHART J, A; MALSPEIS, L; GREVER M R. "Fludarabine Phosphate In Relapsed Non-hodgkin's Lymphoma." Clinical Research. Vol. 33, no. 4. (January 1985.): 891A-.

Grever, M, R; Leiby, J, M; Kraut, E, H; Wilson, H, E; Neidhart, J, A; Wall, R, L; Balcerzak, S P. "Low-dose deoxycoformycin in lymphoid malignancy.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 3, no. 9. (January 1985.): 1196-201.

GREVER M, R; GRAY, D; COLTMAN C, A; HYNES, H; BALCERZAK S P. "Amsacrine 5 Azacytidine And Etoposide In Acute Non-lymphocytic Leukemia In Relapse." Clinical Research. Vol. 33, no. 2 PART 1. (January 1985.): 341A-.

GREVER M, R; CHAPMAN R, A; RATANATHARATHORN, V; SLEASE R B. "An Investigation Of Deoxycoformycin In Advanced Cutaneous T Cell Lymphoma." Clinical Research. Vol. 33, no. 4. (January 1985.): 853A-.

KRAUT E, H; BOURONCLE B, A; GREVER M R. "Treatment Of Hairy Cell Leukemia With Low Dose 2' Deoxycoformycin." Clinical Research. Vol. 33, no. 4. (January 1985.): 835A-.

Camisa, C; Grever, M, R; Bouroncle, B. "Deoxycoformycin: a new chemotherapeutic agent of interest to dermatologists.." Journal of the American Academy of Dermatology. Vol. 12, no. 6. (January 1985.): 1108-9.

Trewyn, R, W; Grever, M R. "Urinary nucleosides in leukemia: laboratory and clinical applications.." Critical reviews in clinical laboratory sciences. Vol. 24, no. 1. (January 1986.): 71-93.

Kraut, E, H; Bouroncle, B, A; Grever, M R. "Low-dose deoxycoformycin in the treatment of hairy cell leukemia.." Blood. Vol. 68, no. 5. (January 1986.): 1119-22.

Livingston, R, B; Schulman, S; Mira, J, G; Harker, G; Vogel, S; Coltman, C A Jr; Rivkin, S, E; Budd, G, T; Grever, M, R; Crowley, J P. "Combined alkylators and multiple-site irradiation for extensive small cell lung cancer: a Southwest Oncology Group Study.." Cancer treatment reports. Vol. 70, no. 12. (January 1986.): 1395-401.

GREVER, G; ROTEVATN, S; SAETERSDAL, T; OKSENDAL, A; JYNGE P. "Ultrastructural Studies Of Intercalated Disc Separation In The Calcium Paradox." Journal of Molecular and Cellular Cardiology. Vol. 18, no. SUPPL. 1. (January 1986.): -.

Leiby, J, M; Snider, K, M; Kraut, E, H; Metz, E, N; Malspeis, L; Grever, M R. "Phase II trial of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in non-Hodgkin's lymphoma: prospective comparison of response with deoxycytidine kinase activity.." Cancer research. Vol. 47, no. 10. (January 1987.): 2719-22.

KRAUT E, H; BOURONCLE B, A; GREVER M R. "Low Dose 2' Deoxycoformycin In The Treatment Of Advanced Hairy Cell Leukemia." Clinical Research. Vol. 35, no. 6. (January 1987.): 850A-.

THEIL K, S; BOURONCLE B, A; GREVER M, R; KRAUT E H. "Bone Marrow Changes In Hairy Cell Leukemia Treated With Low-dose Deoxycoformycin." Clinical Research. Vol. 35, no. 6. (January 1987.): 851A-.

COPELAN, E; JOHNSON, S; GREVER, M; TUTSCHKA P. "A Murine Model For Purging Marrow Of Malignant T Cells." Journal of Cellular Biochemistry Supplement. no. 11 PART A. (January 1987.): 227-.

Copelan, E, A; Johnson, S, C; Grever, M, R; Tutschka, P J. "A murine model for pharmacological marrow purging.." Transplantation proceedings. Vol. 19, no. 1 Pt 3. (January 1987.): 2754-5.

Ryan, D, H; Kopecky, K, J; Head, D; Gumbart, C, N; Grever, M, R; Karanes, C; Weick, J, K; Coltman, C A Jr. "Phase II evaluation of teniposide and ifosfamide in refractory adult acute lymphocytic leukemia: a Southwest Oncology Group Study.." Cancer treatment reports. Vol. 71, no. 7-8. (January 1987.): 713-6.

Grever, M R. "Treatment of patients with acute nonlymphocytic leukemia not in remission.." Seminars in oncology. Vol. 14, no. 4. (January 1987.): 416-24.

Bouroncle, B, A; Grever, M, R; Kraut, E H. "Treatment of hairy cell leukemia: the Ohio State University experience with deoxycoformycin.." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. Vol. 1, no. 4. (January 1987.): 350-4.

Copelan, E, A; Johnson, S, C; Grever, M, R; Sheridan, J, F; Tutschka, P J. "Pharmacologic marrow purging in murine T cell leukemia.." Blood. Vol. 71, no. 6. (January 1988.): 1656-61.

Cheson, B, D; Bennett, J, M; Rai, K, R; Grever, M, R; Kay, N, E; Schiffer, C, A; Oken, M, M; Keating, M, J; Boldt, D, H; Kempin, S J. "Guidelines for clinical protocols for chronic lymphocytic leukemia: recommendations of the National Cancer Institute-sponsored working group.." American journal of hematology. Vol. 29, no. 3. (January 1988.): 152-63.

Leiby, J, M; Grever, M, R; Staubus, A, E; Neidhart, J, A; Malspeis, L. "Phase I clinical investigation of fludarabine phosphate by a loading-dose and continuous-infusion schedule.." Journal of the National Cancer Institute. Vol. 80, no. 6. (January 1988.): 447-9.

LEIBY J, M; GREVER M, R; STAUBUS A, E; NEIDHART J, A; MALSPEIS L. "Phase I Clinical Investigation Of Fludarabine Phosphate By A Loading-dose And Continuous-infusion Schedule." Journal of the National Cancer Institute (Bethesda). Vol. 80, no. 6. (January 1988.): 447-449.

GREVER M, R; KOPECKY K, J; COLTMAN C, A; FILES J, C; GREENBERG B, R; HUTTON J, J; TALLEY, R; VON HOFF D, D; BALCERZAK S P. "Fludarabine Monophosphate A Potentially Useful Agent In Chronic Lymphocytic Leukemia." Nouvelle Revue Francaise d'Hematologie. Vol. 30, no. 5-6. (January 1988.): 457-460.

FRENCH B, T; YAMASAKI E, F; GREVER M, R; GROSJEAN, H; TREWYN R W. "Influence Of Transfer Rna Content And Modification On The Translation Of Synthetic Codons In-vivo." Journal of Cellular Biochemistry Supplement. no. 12 PART D. (January 1988.): 39-.

Kraut, E, H; Bouroncle, B, A; Grever, M R. "Pentostatin in the treatment of advanced hairy cell leukemia.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 7, no. 2. (January 1989.): 168-72.

Head, D, R; Kopecky, K; Bennett, J, M; Grenier, K; Morrison, F, S; Miller, K, B; Grever, M R. "Pathogenetic implications of internuclear bridging in myelodysplastic syndrome. An Eastern Cooperative Oncology Group/Southwest Oncology Group Cooperative Study.." Cancer. Vol. 64, no. 11. (January 1989.): 2199-2202.

Copelan, E, A; Grever, M, R; Kapoor, N; Tutschka, P J. "Marrow transplantation following busulfan and cyclophosphamide for chronic myelogenous leukaemia in accelerated or blastic phase.." British journal of haematology. Vol. 71, no. 4. (January 1989.): 487-91.

Cheson, B, D; Bennett, J, M; Rai, K, R; Grever, M, R; Kay, N, E; Oken, M, M; Schiffer, C, A; Keating, M, J; Boldt, D, H; Kempin, S J. "Chronic lymphocytic leukemia: recommendations.." Annals of internal medicine. Vol. 110, no. 8. (January 1989.): 664-5.

GREVER, M; LEIBY, J; KRAUT, E; METZ, E; NEIDHART, J; BALCERZAK, S; MALSPEIS L. "A Comprehensive Phase I And Ii Clinical Investigation Of Fludarabine Phosphate." Seminars in Oncology. Vol. 17, no. 5 SUPPL. 8. (January 1990.): 39-48.

Kraut, E, H; Crowley, J, J; Grever, M, R; Keppen, M, D; Bonnet, J, D; Hynes, H, E; Salmon, S E. "Phase II study of fludarabine phosphate in multiple myeloma. A Southwest Oncology Group study.." Investigational new drugs. Vol. 8, no. 2. (January 1990.): 199-200.

KRAUT E, H; NEFF J, C; BOURONCLE B, A; GOCHNOUR, D; GREVER M R. "Immunosuppressive Effects Of Pentostatin." Journal of Clinical Oncology. Vol. 8, no. 5. (January 1990.): 848-855.

French, B, T; Patrick, D, E; Grever, M, R; Trewyn, R W. "Differential effect of 6-ethylmercaptopurine on c-myc expression in wild-type and HGPRT-deficient HL-60 cells.." Cancer chemotherapy and pharmacology. Vol. 27, no. 3. (January 1990.): 171-7.

Triozzi, P, L; Rinehart, J, J; Malspeis, L; Young, D, C; Grever, M R. "Immunological effects of flavone acetic acid.." Cancer research. Vol. 50, no. 20. (January 1990.): 6483-5.

MCLEAN I, W; BERD, D; MASTRANGELO M, J; SHIELDS J, A; DAVIDORF F, H; GREVER, M; MAKLEY T, A; GAMEL J W. "A Randomized Study Of Methanol-extraction Residue Of Bcg As Postsurgical Adjuvant Therapy Of Uveal Melanoma." American Journal of Ophthalmology. Vol. 110, no. 5. (January 1990.): 522-526.

Malspeis, L; Grever, M, R; Staubus, A, E; Young, D. "Pharmacokinetics of 2-F-ara-A (9-beta-D-arabinofuranosyl-2-fluoroadenine) in cancer patients during the phase I clinical investigation of fludarabine phosphate.." Seminars in oncology. Vol. 17, no. 5 Suppl 8. (January 1990.): 18-32.

Triozzi, P, L; Avery, K, A; Grever, M, R; Kraut, E H. "Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.." Journal of interferon research. Vol. 10, no. 5. (January 1990.): 535-40.

Grever, M, R; Crowley, J; Salmon, S; McGee, R; Kraut, E, H; Buys, S, S; Rivkin, S E. "Phase II investigation of pentostatin in multiple myeloma: a Southwest Oncology Group study.." Journal of the National Cancer Institute. Vol. 82, no. 22. (January 1990.): 1778-9.

GREVER M R. "A Clinical Update On Deoxycoformycin In Chronic Lymphoproliferative Malignancy." Journal of Cancer Research and Clinical Oncology. Vol. 116, no. SUPPL. PART 2. (January 1990.): 999-.

Cheson, B, D; Cassileth, P, A; Head, D, R; Schiffer, C, A; Bennett, J, M; Bloomfield, C, D; Brunning, R; Gale, R, P; Grever, M, R; Keating, M J. "Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 8, no. 5. (January 1990.): 813-9.

Melink, T, J; Sarosy, G; Hanauske, A, R; Phillips, J, L; Bayne, J, H; Grever, M, R; Jayaram, H, N; Von Hoff, D D. "Phase I trial and biochemical evaluation of tiazofurin administered on a weekly schedule.." Selective cancer therapeutics. Vol. 6, no. 1. (January 1990.): 51-61.

Schweitzer, J; Handley, F, G; Edwards, J; Harris, W, F; Grever, M, R; Schepartz, S, A; Cragg, G; Snader, K; Bhat, A. "Summary of the workshop on Drug Development, Biological Diversity, and Economic Growth.." Journal of the National Cancer Institute. Vol. 83, no. 18. (January 1991.): 1294-8.

French, B, T; Patrick, D, E; Grever, M, R; Trewyn, R W. "Queuine, a tRNA anticodon wobble base, maintains the proliferative and pluripotent potential of HL-60 cells in the presence of the differentiating agent 6-thioguanine.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 88, no. 2. (January 1991.): 370-4.

Grem, J, L; King, S, A; Chun, H, G; Grever, M R. "Cardiac complications observed in elderly patients following 2'-deoxycoformycin therapy.." American journal of hematology. Vol. 38, no. 3. (January 1991.): 245-7.

GRECULA J, C; GAHBAUER, R; BAUER-GIFFIN, C; GOODMAN, J; FAIRCHILD, R; LASTER, B; BRODERICK, G; KANELLITSAS, C; GREVER M. "Radiosensitization Of High Grade Astrocytoma Utilizing Iudr In Combination With Stereotactic Iridium-192 Implantation And External Beam Radiotherapy." International Journal of Radiation Oncology, Biology, Physics. Vol. 21, no. SUPPL. 1. (January 1991.): 193-194.

Grever, Michael; Brager, Paul; Kraut, Eric; Metz, Earl. "A phase Ii investigation of pentostatin in metastatic malignant melanoma." Investigational New Drugs. Vol. 10, no. 4. (January 1992.): 345-346.

SUFFNESS, M; SNADER K, M; CRAGG G, M; SCHEPARTZ S, A; GREVER M R. "History Development And Current Status Of Taxol At The National Cancer Institute." Abstracts of Papers American Chemical Society. Vol. 203, no. 1-3. (January 1992.): MEDI191-.

Grever, M, R; Schepartz, S, A; Chabner, B A. "The National Cancer Institute: cancer drug discovery and development program.." Seminars in oncology. Vol. 19, no. 6. (January 1992.): 622-38.

Weinstein, John N.; Kohn, Kurt W.; Grever, Michael R.; Viswanadhan, Vellarkad N.; Rubinstein, Lawrence V.; Monks, Anne P.; Scudiero, Dominic A.; Welch, Lester; Koutsoukos, Antonis D.. "Neural computing in cancer drug development: Predicting mechanism of action." Science (Washington D C). Vol. 258, no. 5081. (January 1992.): 447-451.

Ryan, D, H; Kopecky, K, J; Head, D; Grever, M, R; Shiaer, S, M; Lipschitz, D, A; Hynes, H, E; Vial, R, H; Veith, R, W; Gumbart, C H. "Analysis of treatment failure in acute nonlymphocytic leukemia patients over fifty years of age. A Southwest Oncology Group study.." American journal of clinical oncology : the official publication of the American Radium Society. Vol. 15, no. 1. (January 1992.): 69-75.

CRAGG G, M; BOYD M, R; CARDELLINA J H, II; GREVER M, R; SCHEPARTZ S, A; SNADER K, M; SUFFNESS M. "The Role Of Plants In The National Cancer Institute Drug Discovery And Development Program." Abstracts of Papers American Chemical Society. Vol. 203, no. 1-3. (January 1992.): AGFD108-.

Weinstein, John N.; Kohn, Kurt W.; Grever, Michael R.; Viswanadhan, Vellarkad N.; Rubinstein, Lawrence V.; Monks, Anne; Scudiero, Dominic A.; Welch, Lester; Koutsoukos, Antonis D.. "Neural computing in the development of new therapies for cancer and Aids." Biophysical Journal. Vol. 64, no. 2 PART 2. (January 1993.): A244-.

Elias, L; Stock-Novack, D; Head, D, R; Grever, M, R; Weick, J, K; Chapman, R, A; Godwin, J, E; Metz, E, N; Appelbaum, F R. "A phase I trial of combination fludarabine monophosphate and chlorambucil in chronic lymphocytic leukemia: a Southwest Oncology Group study.." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. Vol. 7, no. 3. (January 1993.): 361-5.

Grever, Michael; Malspeis, Louis. "The discovery and development of new antileukemic drugs." Hematology-Oncology Clinics of North America. Vol. 7, no. 1. (January 1993.): 233-254.

Cragg, G, M; Schepartz, S, A; Suffness, M; Grever, M R. "The taxol supply crisis. New NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents.." Journal of natural products. Vol. 56, no. 10. (January 1993.): 1657-68.

Feigal, Ellen G.; Christian, Michaele; Cheson, Bruce; Grever, Michael; Friedman, Michael A.. "New chemotherapeutic agents in non-small-cell lung cancer." Seminars in Oncology. Vol. 20, no. 2. (January 1993.): 185-201.

Steeg, P, S; Alley, M, C; Grever, M R. "An added dimension: will three-dimensional cultures improve our understanding of drug resistance?." Journal of the National Cancer Institute. Vol. 86, no. 13. (January 1994.): 953-5.

Dolan, M, E; Pegg, A, E; Moschel, R, C; Vishnuvajjala, B, R; Flora, K, P; Grever, M, R; Friedman, H S. "Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL.." Cancer chemotherapy and pharmacology. Vol. 35, no. 2. (January 1994.): 121-6.

Principe, P.; Broquet, C.; Paull, K.; Grever, M. R.; Coulomb, H.; Huchet, M.; Mencia-Huerta, J. M.; Braquet, P.. "New antineoplastic aza-phospholipids: Synthesis, in vitro cytotoxicity differential cellular sensitivity against seventy human tumor cell lines." International Journal of Oncology. Vol. 4, no. 1. (January 1994.): 29-36.

Plowman, J; Waud, W, R; Koutsoukos, A, D; Rubinstein, L, V; Moore, T, D; Grever, M R. "Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea.." Cancer research. Vol. 54, no. 14. (January 1994.): 3793-9.

Casciari, J, J; Hollingshead, M, G; Alley, M, C; Mayo, J, G; Malspeis, L; Miyauchi, S; Grever, M, R; Weinstein, J N. "Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model.." Journal of the National Cancer Institute. Vol. 86, no. 24. (January 1994.): 1846-52.

Kraut, E, H; Grever, M, R; Bouroncle, B A. "Long-term follow-up of patients with hairy cell leukemia after treatment with 2'-deoxycoformycin.." Blood. Vol. 84, no. 12. (January 1994.): 4061-3.

Scott, A, A; Head, D, R; Kopecky, K, J; Appelbaum, F, R; Theil, K, S; Grever, M, R; Chen, I, M; Whittaker, M, H; Griffith, B, B; Licht, J D. "HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as French-American-British acute myeloid leukemia-M3.." Blood. Vol. 84, no. 1. (January 1994.): 244-55.

Lee, Jong-Seok; Paull, Ken; Alvarez, Manuel; Hose, Curtis; Monks, Anne; Grever, Mike; Fojo, Antonio Tito; Bates, Susan E.. "Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen." Molecular Pharmacology. Vol. 46, no. 4. (January 1994.): 627-638.

Grever, M. R.; Bhatia, K.; Giavazzi, R.; Hollingshead, M.; Magrath, I.; Malspeis, L.; Mayo, J.; Shores, R.. "Experimental therapeutic agents in an Aids-related Scid mouse model." Blood. Vol. 84, no. 10 SUPPL. 1. (January 1994.): 447A-.

Grever, M, R; Benedetti, J; Balcerzak, S, P; Taylor, S, A; Miller, T, P; Dakhil, S R. "A Southwest Oncology Group phase II evaluation of fluderabine monophosphate in sarcoma.." Investigational new drugs. Vol. 12, no. 3. (January 1994.): 259-61.

Alvarez, Manuel; Paull, Ken; Monks, Anne; Hose, Curtis; Lee, Jong-Seok; Weinstein, John; Grever, Mike; Bates, Susan; Fojo, Tito. "Generation of a Drug Resistance Profile by Quantitation of mdr-1/p-glycoprotein in the Cell Lines of the National Cancer Institute Anticancer Drug Screen." Journal of Clinical Investigation. Vol. 95, no. 5. (January 1995.): 2205-2214.

Supko, J. G.; Phillips, L. R.; Grever, M. R.; Vishnuvajjala, B. R.; Sausville, E. A.; Malspeis, L.. "Breflate, a soluble prodrug of brefeldin A for clinical development." Proceedings of the American Association for Cancer Research Annual Meeting. Vol. 36, (January 1995.): 396-.

Suffness, M.; Cragg, G. M.; Grever, M. R.; Grifo, F. J.; Johnson, George; Mead, J. A. R.; Schepartz, S. A.; Venditti, J. M.; Wolpert, M.. "The National Cooperative Natural Products Drug Discovery Group (ncnpddg) and International Cooperative Biodiversity Group (icbg) Programs." International Journal of Pharmacognosy. Vol. 33, no. SUPPL.. (January 1995.): 5-16.

Plowman, J; Dykes, D, J; Narayanan, V, L; Abbott, B, J; Saito, H; Hirata, T; Grever, M R. "Efficacy of the quinocarmycins KW2152 and DX-52-1 against human melanoma lines growing in culture kand in mice.." Cancer research. Vol. 55, no. 4. (January 1995.): 862-7.

Cragg, Gordon M.; Boyd, Michael R.; Grever, Michael R.; Schepartz, Saul A.. "Pharmaceutical prospecting and the potential for pharmaceutical crops: Natural product drug discovery and development at the United States National Cancer Institute." Annals of the Missouri Botanical Garden. Vol. 82, no. 1. (January 1995.): 47-53.

Grever, Michael; Kopecky, Kenneth; Foucar, M. Kathyrn; Head, David; Bennett, John M.; Hutchison, Robert E.; Corbett, William E. N.; Cassileth, Peter A.; Habermann, Thomas; Golomb, Harvey; Rai, Kanit; Eisenhauer, Elizabeth; Appelbaum, Frederick; Cheson, Bruce D.. "Randomized comparison of pentostatin versus interferon alfa-2a in previously untreated patients with hairy cell leukemia: An intergroup study." Journal of Clinical Oncology. Vol. 13, no. 4. (January 1995.): 974-982.

Grever, M. R.; Shinn, C.; Levy, J.. "Ucn-01: A new potential therapeutic agent for chronic lymphocytic leukemia." Blood. Vol. 86, no. 10 SUPPL. 1. (January 1995.): 349A-.

Bigelow, Carolyn L.; Kopecky, Kenneth; Files, Joe C.; Head, David; Lipschitz, David A.; Grever, Michael; Appelbaum, Frederick R.. "Treatment of acute myelogenous leukemia in patients over 50 years of age with V-tad: A Southwest Oncology Group study." American Journal of Hematology. Vol. 48, no. 4. (January 1995.): 228-232.

Tallman, M.; Hakimian, D.; Wheaton, S.; Kopecky, K.; Wollins, E.; Foucar, K.; Cassileth, P.; Habermann, T.; Grever, M.; Peterson, L. C.. "Minimal residual disease in patients with hairy cell leukemia in complete remission: Comparison of 2-chlorodeoxyadenosine with 2-deoxycoformycin and prediction of early relapse." Blood. Vol. 86, no. 10 SUPPL. 1. (January 1995.): 351A-.

Hollingshead, Melinda; Roberson, Joseph; Decker, William; Buckheit., Robert, Jr.; Elder, Cindy; Malspeis, Louis; Mayo, Joseph; Grever, Michael. "In vivo drug screening applications of Hiv-infected cells cultivated within hollow fibres in two physiologic compartments of mice." Antiviral Research. Vol. 28, no. 3. (January 1995.): 265-279.

Hollingshead, M. G.; Grever, M. R.; Steeg, P. S.; Camalier, R. F.; Alley, M. C.; Mayo, J. G.; Venditti, J.; Malspeis, L.. "Status of the Nci breast cancer drug discovery program." Proceedings of the American Association for Cancer Research Annual Meeting. Vol. 36, (January 1995.): 306-.

Burger, A, M; Kaur, G; Alley, M, C; Supko, J, G; Malspeis, L; Grever, M, R; Sausville, E A. "Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)- malononitrile], inhibits cell growth by disrupting mitochondria.." Cancer research. Vol. 55, no. 13. (January 1995.): 2794-9.

Senderowicz, A, M; Kaur, G; Sainz, E; Laing, C; Inman, W, D; Rodriguez, J; Crews, P; Malspeis, L; Grever, M, R; Sausville, E A. "Jasplakinolide's inhibition of the growth of prostate carcinoma cells in vitro with disruption of the actin cytoskeleton.." Journal of the National Cancer Institute. Vol. 87, no. 1. (January 1995.): 46-51.

Weick, James K.; Kopecky, Kenneth J.; Appelbaum, Frederick R.; Head, David R.; Kingsbury, Laura L.; Balcerzak, Stanley P.; Bickers, John N.; Hynes, H. E.; Welborn, Jeanna L.; Simon, Sheryl R.; Grever, Michael. "A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: A Southwest Oncology Group study." Blood. Vol. 88, no. 8. (January 1996.): 2841-2851.

Sausville, E, A; Duncan, K, L; Senderowicz, A; Plowman, J; Randazzo, P, A; Kahn, R; Malspeis, L; Grever, M R. "Antiproliferative effect in vitro and antitumor activity in vivo of brefeldin A.." The cancer journal from Scientific American. Vol. 2, no. 1. (January 1996.): 52-8.

Gore, S. D.; Miller, C. B.; Weng, L.-J.; Burks, K.; Griffin, C. A.; Chen, T.-L.; Burke, P. J.; Grever, M.; Rowinsky, E. K.. "Improved hematopoiesis in patients with myelodysplastic syndromes (mds) and acute myeloid leukemia (aml) following administration of the putative differentiating agent sodium phenylbutyrate (spb)." Blood. Vol. 88, no. 10 SUPPL. 1 PART 1-2. (January 1996.): 582A-.

Flinn, I. W.; Byrd, J. C.; Seifter, E.; Marcellus, D.; Lee, N.; Diehl, L. F.; Ambinder, R. F.; Grever, M. R.; Vogelsang, G.. "Fludarabine and cyclophosphamide as first therapy for indolent lymphoproliferative disorders: Response rates and toxicity." Blood. Vol. 88, no. 10 SUPPL. 1 PART 1-2. (January 1996.): 589A-.

Flinn, I, W; Grever, M R. "Chronic lymphocytic leukemia.." Cancer treatment reviews. Vol. 22, no. 1. (January 1996.): 1-13.

Fitzsimmons, Sara A.; Workman, Paul; Grever, Michael; Paull, Kenneth; Camalier, Richard; Lewis, Alexander D.. "Reductase enzyme expression across the National Cancer Institute tumor cell line panel: Correlation with sensitivity to mitomycin C and Eo9." Journal of the National Cancer Institute (Bethesda). Vol. 88, no. 5. (January 1996.): 259-269.

Cheson, Bruce D.; Bennett, John M.; Grever, Michael; Kay, Neil; Keating, Michael J.; O'Brien, Susan; Rai, Kanti R.. "National Cancer Institute-sponsored Working Group Guidelines for Chronic Lymphocytic Leukemia: Revised guidelines for diagnosis and treatment." Blood. Vol. 87, no. 12. (January 1996.): 4990-4997.

Keohan, M, L; Grever, M, R; Balcerzak, S, P; Antman, K. "A phase II Southwest Oncology Group study of cisplatin and continuous infusion vinblastine in the treatment of advanced soft tissue sarcoma.." Investigational new drugs. Vol. 15, no. 3. (January 1997.): 255-6.

Gore, S. D.; Miller, C. B.; Weng, L.-J.; Burks, K.; Griffin, C. A.; Chen, T.-L.; Smith, V.; Burke, P. J.; Grever, M.; Rowinsky, E. K.. "Clinical development of sodium phenylbutyrate (spb) as a putative differentiating agent in myeloid malignancies." Anticancer Research. Vol. 17, no. 5C. (January 1997.): 3938-.

Freije, Jose M. P.; Lawrence, Julia A.; Hollingshead, Melinda G.; De La Rosa, Abel; Narayanan, Ven; Grever, Michael; Sausville, Edward A.; Paull, Kenneth; Steeg, Patricia S.. "Identification of compounds with preferential inhibitory activity against low-nm23-expressing human breast carcinoma and melanoma cell lines." Nature Medicine. Vol. 3, no. 4. (January 1997.): 395-401.

Flinn, I. W.; Kopecky, K. J.; Foucar, M. K.; Head, D.; Bennett, J. M.; Hutchison, R. E.; Corbett, W. E. N.; Cassileth, P. A.; Habermann, T.; Golomb, H.; Rai, K.; Eisenhauser, E.; Appelbaum, F. R.; Cheson, B. D.; Grever, M.. "Long-term results in hairy cell leukemia (hcl) treated with pentostatin." Blood. Vol. 90, no. 10 SUPPL. 1 PART 1. (January 1997.): 578A-.

Byrd, J. C.; Waselenko, J. K.; Shinn, C. A.; Miller, C.; Gore, S.; Sausville, E.; Grever, M. R.. "Fr901228, a novel antitumor bicyclic depsipeptide, has marked in vitro activity against both the K-562 cell line and human acute leukemia cells." Blood. Vol. 90, no. 10 SUPPL. 1 PART 2. (January 1997.): 238B-.

Byrd, J. C.; Waselenko, J. K.; Shinn, C. A.; Flinn, I. W.; Diehl, L. F.; Grever, M.. "Interleukin-4 induces resistance to F-ara-a and Unc-01, but not flavopiridol in a Bcl-2 independent manner." Blood. Vol. 90, no. 10 SUPPL. 1 PART 1. (January 1997.): 532A-.

Byrd, J. C.; Waselenko, J. K.; Shinn, C. A.; Bedi, A.; Flinn, I. W.; Diehl, L. F.; Sausville, E.; Grever, M. R.. "Fr901228, a novel antitumor bicyclic depsipeptide, has significant in vitro activity against human B-chronic lymphocytic leukemia (b-cll)." Blood. Vol. 90, no. 10 SUPPL. 1 PART 1. (January 1997.): 532A-.

Byrd, J. C.; Shinn, C. A.; Bedi, A.; Waselenko, J. K.; Fuchs, E.; Flinn, I. W.; Diehl, L. F.; Sausville, E.; Grever, M. R.. "Flavopiridol has marked in vitro activity against human B-chronic lymphocytic leukemia (b-cll) and induces apoptosis independent of p53 status." Blood. Vol. 90, no. 10 SUPPL. 1 PART 1. (January 1997.): 531A-.

Byrd, J, C; Shinn, C; Waselenko, J, K; Fuchs, E, J; Lehman, T, A; Nguyen, P, L; Flinn, I, W; Diehl, L, F; Sausville, E; Grever, M R. "Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.." Blood. Vol. 92, no. 10. (January 1998.): 3804-16.

Byrd, J, C; Rai, K, R; Sausville, E, A; Grever, M R. "Old and new therapies in chronic lymphocytic leukemia: now is the time for a reassessment of therapeutic goals.." Seminars in oncology. Vol. 25, no. 1. (January 1998.): 65-74.

Byrd, J, C; Flinn, I, W; Grever, M R. "Introduction: chronic lymphocytic leukemia.." Seminars in oncology. Vol. 25, no. 1. (January 1998.): 4-5.

Wortmann, G, W; Aronson, N, E; Byrd, J, C; Grever, M, R; Oster, C N. "Herpes zoster and lymphopenia associated with sodium stibogluconate therapy for cutaneous leishmaniasis.." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Vol. 27, no. 3. (January 1998.): 509-12.

Orlowski, R, Z; Eswara, J, R; Lafond-Walker, A; Grever, M, R; Orlowski, M; Dang, C V. "Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor.." Cancer research. Vol. 58, no. 19. (January 1998.): 4342-8.

O'Donnell, P. V.; Jones, R. J.; Vogelsang, G. B.; Seber, A.; Ambinder, R. F.; Flinn, I.; Miller, C.; Marcellus, D. C.; Griffin, C.; Abrams, R.; Braine, H. G.; Grever, M.; Hess, A. D.; Piantadosi, S.; Noga, S. J.. "Cd34+ stem cell augmentation of elutriated allogeneic bone marrow grafts: Results of a phase Ii clinical trial of engraftment and graft-versus-host disease prophylaxis in high-risk hematologic malignancies." Bone Marrow Transplantation. Vol. 22, no. 10. (January 1998.): 947-955.

Gore, S. D.; Weng, L.-J.; Griffin, C. A.; Noe, D.; Burks, K.; Hawkins, A.; Smith, V.; Dover, G.; Grever, M.; Miller, C. B.. "Impact of prolonged administration of the putative differentiating agent sodium phenylbutyrate (pb) on hematopoiesis in myelodysplastic syndrome (mds) and acute myeloid leukemia (aml)." Blood. Vol. 92, no. 10 SUPPL. 1 PART 1-2. (January 1998.): 633A-.

Gore, S, D; Rowinsky, E, K; Miller, C, B; Griffin, C; Chen, T, L; Borowitz, M; Donehower, R, C; Burks, K, L; Armstrong, D, K; Burke, P, J; Grever, M, R; Kaufmann, S H. "A phase II "window" study of topotecan in untreated patients with high risk adult acute lymphoblastic leukemia.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 4, no. 11. (January 1998.): 2677-89.

Byrd, John C.; Rai, Kanti R.; Sausville, Edward A.; Grever, Michael R.. "Old and new therapies in chronic lymphocytic leukemia: Now is the time for a reassessment of therapeutic goals." Seminars in Oncology. Vol. 25, no. 1. (January 1998.): 65-74.

Byrd, J. C.; Shinn, C. A.; Kanakry, C.; Ravi, R.; Willis, C. W.; Drabick, J. J.; Sausville, E.; Grever, M. R.. "Spicamycin derivative Krn5500 has marked in vitro activity against human B-chronic lymphocytic leukemia (b-cll) cells concomitant with decreased expression of p27kip1 and cleavage of caspase-3." Blood. Vol. 92, no. 10 SUPPL. 1 PART 1-2. (January 1998.): 491A-.

Ali, M.; Grever, M. R.. "A cytotoxic naphthoquinone from Lawsonia inermis." Fitoterapia. Vol. 69, no. 2. (January 1998.): 181-183.

Nousari, H, C; Brodsky, R, A; Jones, R, J; Grever, M, R; Anhalt, G J. "Immunoablative high-dose cyclophosphamide without stem cell rescue in paraneoplastic pemphigus: report of a case and review of this new therapy for severe autoimmune disease.." Journal of the American Academy of Dermatology. Vol. 40, no. 5 Pt 1. (January 1999.): 750-4.

Karanes, C; Kopecky, K, J; Head, D, R; Grever, M, R; Hynes, H, E; Kraut, E, H; Vial, R, H; Lichtin, A; Nand, S; Samlowski, W, E; Appelbaum, F R. "A phase III comparison of high dose ARA-C (HIDAC) versus HIDAC plus mitoxantrone in the treatment of first relapsed or refractory acute myeloid leukemia Southwest Oncology Group Study.." Leukemia research. Vol. 23, no. 9. (January 1999.): 787-94.

Gore, S. D.; Weng, L.-J.; Yu, K.; Fu, S.; Griffin, C. A.; Noe, D.; Hawkins, A.; Smith, V.; Dover, G.; Grever, M.; Miller, C. B.. "Clinical development of the putative differentiating agent phenylbutyrate for the treatment of myelodysplasia and acute myeloid leukemia." Leukemia Research. Vol. 23, no. SUPPL. 1. (January 1999.): S71-.

Byrd, J, C; Shinn, C; Ravi, R; Willis, C, R; Waselenko, J, K; Flinn, I, W; Dawson, N, A; Grever, M R. "Depsipeptide (FR901228): a novel therapeutic agent with selective, in vitro activity against human B-cell chronic lymphocytic leukemia cells.." Blood. Vol. 94, no. 4. (January 1999.): 1401-8.

Leith, C, P; Kopecky, K, J; Chen, I, M; Eijdems, L; Slovak, M, L; McConnell, T, S; Head, D, R; Weick, J; Grever, M, R; Appelbaum, F, R; Willman, C L. "Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study.." Blood. Vol. 94, no. 3. (January 1999.): 1086-99.

Flinn, I, W; Byrd, J, C; Morrison, C; Jamison, J; Diehl, L, F; Murphy, T; Piantadosi, S; Seifter, E; Ambinder, R, F; Vogelsang, G; Grever, M R. "Fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated indolent lymphoid malignancies.." Blood. Vol. 96, no. 1. (January 2000.): 71-5.

Byrd, John C.; Grever, Michael R.; Waselenko, Jamie K.; Willis, Carl R.; Park, Kathy; Goodrich, Amy; Lucas, Margaret A.; Shinn, Charlotte; Flinn, Ian W.. "Theophylline, pentostatin (nipent), and chlorambucil: A dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders." Seminars in Oncology. Vol. 27, no. 2 Suppl. 5. (January 2000.): 37-40.

Byrd, J, C; Waselenko, J, K; Keating, M; Rai, K; Grever, M R. "Novel therapies for chronic lymphocytic leukemia in the 21st century.." Seminars in oncology. Vol. 27, no. 5. (January 2000.): 587-97.

Byrd, J, C; Grever, M, R; Waselenko, J, K; Willis, C, R; Park, K; Goodrich, A; Lucas, M, A; Shinn, C; Flinn, I W. "Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders.." Seminars in oncology. Vol. 27, no. 2 Suppl 5. (January 2000.): 37-40.

Alizadeh, A, A; Eisen, M, B; Davis, R, E; Ma, C; Lossos, I, S; Rosenwald, A; Boldrick, J, C; Sabet, H; Tran, T; Yu, ; XPowell, J, I; Yang, L; Marti, G, E; Moore, T; Hudson, J Jr; Lu, L; Lewis, D, B; Tibshirani, R; Sherlock, G; Chan, W, C; et al.. "Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.." Nature. Vol. 403, no. 6769. (January 2000.): 503-11.

Waselenko, J, K; Grever, M, R; Beer, M; Lucas, M, A; Byrd, J C. "Pentostatin (Nipent) and chlorambucil with granulocyte-macrophage colony-stimulating factor support for patients with previously untreated, treated, and fludarabine-refractory B-cell chronic lymphocytic leukemia.." Seminars in oncology. Vol. 27, no. 2 Suppl 5. (January 2000.): 44-51.

Margolis, J; Grever, M R. "Pentostatin (Nipent): a review of potential toxicity and its management.." Seminars in oncology. Vol. 27, no. 2 Suppl 5. (January 2000.): 9-14.

Alizadeh, Ash; Eisen, Michael B.; Davis, R. Eric; Ma, Chi; Sabet, Hajeer; Tran, Truc H.; Powell, John I.; Yang, Liming; Marti, Gerald; Chan, Wing C.; Greiner, Timothy C.; Weisenburger, Dennis D.; Armitage, James O.; Grever, Michael; Byrd, John; Wilson, Wyndham; Lossos, Izadore; Levy, Ron; Botstein, David; Brown, Patrick O.; et al.. "New cancer types defined by gene expression profiling." Acta Haematologica (Basel). Vol. 103, no. Supplement 1. (January 2000.): 90-.

Flinn, I, W; Kopecky, K, J; Foucar, M, K; Head, D; Bennett, J, M; Hutchison, R; Corbett, W; Cassileth, P; Habermann, T; Golomb, H; Rai, K; Eisenhauer, E; Appelbaum, F; Cheson, B; Grever, M R. "Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin.." Blood. Vol. 96, no. 9. (January 2000.): 2981-6.

Byrd, J. C.; Grever, M. R.; Willis, C. R.; Waselenko, J. K.; Park, K.; Goodrich, A.; Lucas, M. A.; Shinn, C.; Diehl, L. F.; Flinn, I. W.. "Theophylline, pentostatin, and chromabucil: A dose escalation study to modulate intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders." Cancer Investigation. Vol. 18, no. SUPPL. 1. (January 2000.): 114-.

Byrd, John C.; Murphy, Timothy; Howard, Robin S.; Lucas, Margaret S.; Goodrich, Amy; Park, Kathy; Pearson, Michael; Waselenko, Jamie K.; Ling, Geoffrey; Grever, Michael R.; Grillo-Lopez, Antonio J.; Rosenberg, Jay; Kunkel, Lori; Flinn, Ian W.. "Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity." Journal of Clinical Oncology. Vol. 19, no. 8. (January 2001.): 2153-2164.

Byrd, John C.; Grever, Michael R.; Flinn, Ian W.; Waselenko, Jamie K.. "Combination therapy for lymphoproliferative diseases." Official Gazette of the United States Patent and Trademark Office Patents. Vol. 1252, no. 2. (January 2001.): -.

Byrd, J, C; Shinn, C; Willis, C, R; Flinn, I, W; Lehman, T; Sausville, E; Lucas, D; Grever, M R. "UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism.." Experimental hematology. Vol. 29, no. 6. (January 2001.): 703-8.

Waselenko, J, K; Shinn, C, A; Willis, C, R; Flinn, I, W; Grever, M, R; Byrd, J C. "Carboxyamido-triazole (CAI)--a novel "static" signal transduction inhibitor induces apoptosis in human B-cell chronic lymphocytic leukemia cells.." Leukemia & lymphoma. Vol. 42, no. 5. (January 2001.): 1049-53.

Waselenko, J, K; Grever, M, R; Shinn, C, A; Flinn, I, W; Byrd, J C. "Gemcitabine demonstrates in vitro activity against human B-cell chronic lymphocytic leukemia.." Leukemia research. Vol. 25, no. 6. (January 2001.): 435-40.

Christian, B. T.; Mantil, J.; Satter, M. R.; Dunigan, K.; Jacobs, M.; Kraut, E. H.; Grever, M.; Balcerzak, S.. "Using Pet to monitor tumor response to antiangiogenic therapy: Changes in tumor blood flow and Fdg metabolism in patients during therapy." Journal of Nuclear Medicine. Vol. 42, no. 5 Supplement. (January 2001.): 299P-.

Flinn, Ian W.; Jemiai, Yannis; Bennett, John M.; Falkson, Carla I.; Flynn, Patrick; Pundaleeka, Sarode; Stadtmauer, Edward; Schnell, Frederick; Grever, Michael; Tallman, Martin S.; Rowe, Jacob M.. "Fludarabine and cyclophosphamide achieves high complete response rate in patients with previously untreated chronic lymphocytic leukemia: Ecog 1997." Blood. Vol. 98, no. 11 Part 1. (January 2001.): 633a-.

Byrd, J, C; Murphy, T; Howard, R, S; Lucas, M, S; Goodrich, A; Park, K; Pearson, M; Waselenko, J, K; Ling, G; Grever, M, R; Grillo-Lopez, A, J; Rosenberg, J; Kunkel, L; Flinn, I W. "Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 19, no. 8. (January 2001.): 2153-64.

Ali, M.; Ansari, S. H.; Grever, M. R.. "Cytotoxic alkaloids from Tylophora indica." Pharmazie. Vol. 56, no. 2. (January 2001.): 188-190.

Rosenwald, A; Alizadeh, A, A; Widhopf, G; Simon, R; Davis, R, E; Yu, ; XYang, L; Pickeral, O, K; Rassenti, L, Z; Powell, J; Botstein, D; Byrd, J, C; Grever, M, R; Cheson, B, D; Chiorazzi, N; Wilson, W, H; Kipps, T, J; Brown, P, O; Staudt, L M. "Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia.." The Journal of experimental medicine. Vol. 194, no. 11. (January 2001.): 1639-47.

Liu, Jing; Kraut, Eric; Bender, Jonathan; Brooks, Rebecca; Balcerzak, Stanley; Grever, Michael; Stanley, Harriet; D'Ambrosio, Steven; Gibson-D'Ambrosio, Ruth; Chan, Kenneth K.. "Pharmacokinetics of oxaliplatin (nsc 266046) alone and in combination with paclitaxel in cancer patients." Cancer Chemotherapy and Pharmacology. Vol. 49, no. 5. (January 2002.): 367-374.

Liu, Jing; Kraut, Eric H.; Balcerzak, Stanley; Grever, Michael; D'Ambrosio, Steven; Chan, Kenneth K.. "Dosing sequence-dependent pharmacokinetic interaction of oxaliplatin with paclitaxel in the rat.." Cancer Chemotherapy and Pharmacology. Vol. 50, no. 6. (January 2002.): 445-453.

Gore, Steven, D; Weng, Li-Jun; Figg, William, D; Zhai, Suoping; Donehower, Ross, C; Dover, George; Grever, Michael, R; Griffin, Constance; Grochow, Louise, B; Hawkins, Anita; Burks, Kathleen; Zabelena, Yelena; Miller, Carole B. "Impact of prolonged infusions of the putative differentiating agent sodium phenylbutyrate on myelodysplastic syndromes and acute myeloid leukemia.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 8, no. 4. (January 2002.): 963-70.

Marcucci, Guido; Byrd, John C.; Dai, Guowei; Klisovic, Marko I.; Kourlas, Peter J.; Young, Donn C.; Cataland, Spero R.; Fisher, Diane B.; Lucas, David; Chan, Kenneth K.; Porcu, Pierluigi; Lin, Zhong-Pin; Farag, Sherif F.; Frankel, Stanley R.; Zwiebel, James A.; Kraut, Eric H.; Balcerzak, Stanley P.; Bloomfield, Clara D.; Grever, Michael R.; Caligiuri, Michael A.. "Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia.." Blood. Vol. 101, no. 2. (January 2003.): 425-432.

Klisovic, M, I; Maghraby, E, A; Parthun, M, R; Guimond, M; Sklenar, A, R; Whitman, S, P; Chan, K, K; Murphy, T; Anon, J; Archer, K, J; Rush, L, J; Plass, C; Grever, M, R; Byrd, J, C; Marcucci, G. "Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. Vol. 17, no. 2. (January 2003.): 350-8.

Byrd, John, C; Lucas, David, M; Mone, Andrew, P; Kitner, Joshua, B; Drabick, Joseph, J; Grever, Michael R. "KRN5500: a novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis.." Blood. Vol. 101, no. 11. (January 2003.): 4547-50.

Aron, Jennifer L.; Parthun, Mark R.; Marcucci, Guido; Kitada, Shinichi; Mone, Andrew P.; Davis, Melanie E.; Shen, Tiansheng; Murphy, Timothy; Wickham, Joseph; Kanakry, Chris; Lucas, David M.; Reed, John C.; Grever, Michael R.; Byrd, John C.. "Depsipeptide (fr901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-flip protein.." Blood. Vol. 102, no. 2. (January 2003.): 652-658.

Pavletic, Steven Z.; Bociek, R. Gregory; Foran, James M.; Rubocki, Ronald J.; Kuszynski, Charles A.; Wisecarver, James L.; Hatcher, Lori; Lucas, David M.; Byrd, John C.; Grever, Michael R.; Joshi, Shantaram S.; Hardiman, Penny; Smith, Lynette M.; McGuire, Timothy R.; Bierman, Philip J.; Vose, Julie M.; Armitage, James O.; Talmadge, James E.. "Lymphodepleting effects and safety of pentostatin for nonmyeloablative allogeneic stem-cell transplantation.." Transplantation (Hagerstown). Vol. 76, no. 5. (January 2003.): 877-881.

Grever, Michael, R; Doan, Charles, A; Kraut, Eric H. "Pentostatin in the treatment of hairy-cell leukemia.." Best practice & research. Clinical haematology. Vol. 16, no. 1. (January 2003.): 91-9.

Xiao, Jim; Byrd, John; Marcucci, Guido; Grever, Michael; Covey, Joseph; Wright, John; Chan, Kenneth K.. "Disposition of depsipeptide Fk228 (fr 901228, Nsc 630176) in the rat.." Proceedings of the American Association for Cancer Research Annual Meeting. Vol. 44, (January 2003.): 155-.

Xiao, Jim J.; Byrd, John; Marcucci, Guido; Grever, Michael; Chan, Kenneth K.. "Identification of thiols and glutathione conjugates of depsipeptide Fk228 (fr901228), a novel histone protein deacetylase inhibitor, in the blood.." Rapid Communications in Mass Spectrometry. Vol. 17, no. 8. (January 2003.): 757-766.

Grever, Michael R. "New drugs in acute myeloid leukemia.." Clin Adv Hematol Oncol. Vol. 1, no. 8. (January 2003.): 456-9.

Dai, Guo Wei; Chan, Kenneth K.; Hoyt, Dale; Shen, Tian Sheng; Grever, Michael; Caligiuri, Michael; Byrd, John; Marcucci, Guido. "A novel, highly sensitive fluorogenic Elisa assay for Bcl-2 antisense phosphorothioate polynucleotide G3139 in biological matrices.." Proceedings of the American Association for Cancer Research Annual Meeting. Vol. 44, (January 2003.): 1299-.

Marcucci, G.; Stock, W.; Dai, G.; Klisovic, M. I.; Maharry, K.; Shen, T.; Liu, S.; Sher, D. A.; Lucas, D.; Zwiebel, J. A.; Larson, R. A.; Caligiuri, M. A.; Bloomfield, C. D.; Chan, K. K.; Grever, M. R.; Byrd, J. C.. "G3139, a Bcl-2 antisense oligo-nucleotide, in Aml.." Annals of Hematology. Vol. 83, no. Supplement 1. (January 2004.): S93-S94.

Lucas, D, M; Davis, M, E; Parthun, M, R; Mone, A, P; Kitada, S; Cunningham, K, D; Flax, E, L; Wickham, J; Reed, J, C; Byrd, J, C; Grever, M R. "The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells.." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. Vol. 18, no. 7. (January 2004.): 1207-14.

Lozanski, Gerard; Heerema, Nyla A.; Flinn, Ian W.; Smith, Lisa; Harbison, Jennifer; Webb, Jennifer; Moran, Mollie; Lucas, Margaret; Lin, Thomas; Hackbarth, Marcy L.; Proffitt, John H.; Lucas, David; Grever, Michael R.; Byrd, John C.. "Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions." Blood. Vol. 103, no. 9. (January 2004.): 3278-3281.

Lin, Thomas, S; Moran, Mollie; Lucas, Margaret; Waymer, Sharon; Jefferson, Sara; Fischer, Diane, B; Grever, Michael, R; Byrd, John C. "Antibody therapy for chronic lymphocytic leukemia: a promising new modality.." Hematology/oncology clinics of North America. Vol. 18, no. 4. (January 2004.): 895-913, ix.

Eisenbeis, Charles, F; Grainger, Andrew; Fischer, Beth; Baiocchi, Robert, A; Carrodeguas, Lester; Roychowdhury, Sameek; Chen, Lei; Banks, Amy, L; Davis, Thomas; Young, Donn; Kelbick, Nicole; Stephens, Julie; Byrd, John, C; Grever, Michael, R; Caligiuri, Michael, A; Porcu, Pierluigi. "Combination immunotherapy of B-cell non-Hodgkin's lymphoma with rituximab and interleukin-2: a preclinical and phase I study.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 10, no. 18 Pt 1. (January 2004.): 6101-10.

Roychowdhury, Sameek; Baiocchi, Robert A.; Vourganti, Srinivas; Bhatt, Darshna; Blaser, Bradley W.; Freud, Aharon G.; Chou, Jason; Chen, Chang-Shi; Xiao, Jim J.; Parthun, Mark; Chan, Kenneth K.; Ferketich, Charles F.; Grever, Michael R.; Chen, Ching-Shih; Caligiuri, Michael A.. "Selective efficacy of depsipeptide in a xenograft model of Epstein-barr virus-positive lymphoproliferative disorder." Journal of the National Cancer Institute (Cary). Vol. 96, no. 19. (January 2004.): 1447-1457.

Flinn, Ian W.; Kumm, Elizabeth; Grever, Michael R.; Neuberg, Donna; Dewald, Gordon W.; Bennett, John M.; Paietta, Elisabeth M.; Appelbaum, Frederick R.; Larson, Richard A.; Hussein, Mohamad A.; Moore, Dennis F. Jr; Tallman, Martin S.. "Fludarabine and cyclophosphamide produces a higher complete response rate and more durable remissions than fludarabine in patients with previously untreated Cll: Intergroup trial E2997.." Blood. Vol. 104, no. 11, Part 1. (January 2004.): 139A-.

Xiao, Jim J.; Huang, Ying; Dai, Zunyan; Sadee, Wolfgang; Chen, Jiyun; Liu, Shujun; Marcucci, Guido; Byrd, John; Covey, Joseph M.; Wright, John; Grever, Michael; Chan, Kenneth K.. "Chemoresistance to depsipeptide Fk228 [(e)-(1s,4s,10s,21r)-7-[(z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible Mdr1 induction in human cancer cell lines." Journal of Pharmacology and Experimental Therapeutics. Vol. 314, no. 1. (January 2005.): 467-475.

Raval, Aparna; Lucas, David, M; Matkovic, Jennifer, J; Bennett, Kristi, L; Liyanarachchi, Sandya; Young, Donn, C; Rassenti, Laura; Kipps, Thomas, J; Grever, Michael, R; Byrd, John, C; Plass, Christoph. "TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 23, no. 17. (January 2005.): 3877-85.

Bolanos-Meade, Javier; Jacobsohn, David, A; Margolis, Jeffrey; Ogden, Adam; Wientjes, M Guillaume; Byrd, John, C; Lucas, David, M; Anders, Viki; Phelps, Michele; Grever, Michael, R; Vogelsang, Georgia B. "Pentostatin in steroid-refractory acute graft-versus-host disease.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 23, no. 12. (January 2005.): 2661-8.

Lin, Thomas, S; Grever, Michael, R; Byrd, John C. "Changing the way we think about chronic lymphocytic leukemia.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 23, no. 18. (January 2005.): 4009-12.

Lin, T, S; Flinn, I, W; Lucas, M, S; Porcu, P; Sickler, J; Moran, M, E; Lucas, D, M; Heerema, N, A; Grever, M, R; Byrd, J C. "Filgrastim and alemtuzumab (Campath-1H) for refractory chronic lymphocytic leukemia.." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. Vol. 19, no. 7. (January 2005.): 1207-10.

Byrd, John, C; Peterson, Bercedis, L; Gabrilove, Janice; Odenike, Olatoyosi, M; Grever, Michael, R; Rai, Kanti; Larson, Richard, A; Larson, Richard A. "Treatment of relapsed chronic lymphocytic leukemia by 72-hour continuous infusion or 1-hour bolus infusion of flavopiridol: results from Cancer and Leukemia Group B study 19805.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 11, no. 11. (January 2005.): 4176-81.

Byrd, John, C; Marcucci, Guido; Parthun, Mark, R; Xiao, Jim, J; Klisovic, Rebecca, B; Moran, Mollie; Lin, Thomas, S; Liu, Shujun; Sklenar, Amy, R; Davis, Melanie, E; Lucas, David, M; Fischer, Beth; Shank, Roshini; Tejaswi, Sooraj, L; Binkley, Philip; Wright, John; Chan, Kenneth, K; Grever, Michael R. "A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.." Blood. Vol. 105, no. 3. (January 2005.): 959-67.

Byrd, John C.; Marcucci, Guido; Parthun, Mark R.; Xiao, Jim J.; Klisovic, Rebecca B.; Moran, Mollie; Lin, Thomas S.; Liu, Shujun; Sklenar, Amy R.; Davis, Melanie E.; Lucas, David M.; Fischer, Beth; Shank, Roshini; Tejaswi, Sooraj L.; Binkley, Philip; Wright, John; Chan, Kenneth K.; Grever, Michael R.. "A phase 1 and pharmacodynamic study of depsipeptide (fk228) in chronic lymphocytic leukemia and acute myeloid leukemia." Blood. Vol. 105, no. 3. (January 2005.): 959-967.

Tseng, Ping-Hui; Lin, Ho-Pi; Zhu, Jiuxiang; Chen, Kuen-Feng; Hade, Erinn M.; Young, Donn C.; Byrd, John C.; Grever, Michael; Johnson, Kara; Druker, Brian J.; Chen, Ching-Shih. "Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor Osu-03012 in overcoming imatinib mesylate resistance." Blood. Vol. 105, no. 10. (January 2005.): 4021-4027.

Marcucci, Guido; Stock, Wendy; Dai, Guowei; Klisovic, Rebecca, B; Liu, Shujun; Klisovic, Marko, I; Blum, William; Kefauver, Cheryl; Sher, Dorie, A; Green, Margaret; Moran, Mollie; Maharry, Kati; Novick, Steven; Bloomfield, Clara, D; Zwiebel, James, A; Larson, Richard, A; Grever, Michael, R; Chan, Kenneth, K; Byrd, John C. "Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 23, no. 15. (January 2005.): 3404-11.

Lin, T. S.; Flinn, I. W.; Lucas, M. S.; Porcu, P.; Sickler, J.; Moran, M. E.; Lucas, D. M.; Heerema, N., A; Grever, M. R.; Byrd, J. C.. "Filgrastim and alemtuzumab (campath-1h) for refractory chronic lymphocytic leukemia." Leukemia (Basingstoke). Vol. 19, no. 7. (January 2005.): 1207-1210.

Gore, Steven D.; Smith, B. Douglas; Gojo, Ivana; Grever, Michael; Kaufmann, Scott H.; Letendre, Louis; Leonard, Debra G. B.; Marcucci, Guido; Miller, Carole B.; Morris, Lawrence; Piantadosi, Steven; Prior, Thomas; Stock, Wendy; Karp, Judith E.. "Durable molecular remissions with a single cycle of timed sequential consolidation chemotherapy in acute promyelocytic leukemia." American Journal of Hematology. Vol. 79, no. 2. (January 2005.): 119-127.

Otterson, G. A.; Lavelle, J.; Villalona-Calero, M. A.; Shah, M.; Wei, X.; Chan, K. K.; Fischer, B.; Grever, M.. "A phase I clinical and pharmacokinetic study of fenretinide combined with paclitaxel and cisplatin for refractory solid tumors." Investigational New Drugs. Vol. 23, no. 6. (January 2005.): 555-562.

Johnson, Amy J.; Smith, Lisa L.; Zhu, Jiuxiang; Heerema, Nyla A.; Jefferson, Sara; Mone, Andrew; Grever, Michael; Chen, Ching-Shih; Byrd, John C.. "A novel celecoxib derivative, Osu03012, induces cytotoxicity in primary Cll cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism." Blood. Vol. 105, no. 6. (January 2005.): 2504-2509.

Lucas, David M.; Parthun, Mark R.; Byrd, John C.; Grever, Michael R.. "Treatment of patients with chronic lymphocytic leukemia." Official Gazette of the United States Patent and Trademark Office Patents. (January 2005.): -.

Kasamon, Yvette, L; Flinn, Ian, W; Grever, Michael, R; Diehl, Louis, F; Garrett-Mayer, Elizabeth; Goodman, Steven, N; Lucas, Margaret, S; Byrd, John C. "Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 11, no. 23. (January 2005.): 8413-7.

Flinn, Ian, W; Byrd, John, C; Bartlett, Nancy; Kipps, Thomas; Gribben, John; Thomas, Deborah; Larson, Richard, A; Rai, Kanti; Petric, Rosemary; Ramon-Suerez, Jose; Gabrilove, Janice; Grever, Michael R. "Flavopiridol administered as a 24-hour continuous infusion in chronic lymphocytic leukemia lacks clinical activity.." Leukemia research. Vol. 29, no. 11. (January 2005.): 1253-7.

Flinn, Ian W.; Byrd, John C.; Bartlett, Nancy; Kipps, Thomas; Gribben, John; Thomas, Deborah; Larson, Richard A.; Rai, Kanti; Petric, Rosemary; Ramon-Suerez, Jose; Gabrilove, Janice; Grever, Michael R.. "Flavopiridol administered as a 24-hour continuous infusion in chronic lymphocytic leukemia lacks clinical activity." Leukemia Research. Vol. 29, no. 11. (January 2005.): 1253-1257.

Byrd, John, C; Lin, Thomas, S; Grever, Michael R. "Treatment of relapsed chronic lymphocytic leukemia: old and new therapies.." Seminars in oncology. Vol. 33, no. 2. (January 2006.): 210-9.

Byrd, John, C; Gribben, John, G; Peterson, Bercedis, L; Grever, Michael, R; Lozanski, Gerard; Lucas, David, M; Lampson, Ben; Larson, Richard, A; Caligiuri, Michael, A; Heerema, Nyla A. "Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 24, no. 3. (January 2006.): 437-43.

Waselenko, Jamie K.; Reese, Amy; Park, Kathy; Lucas, Margaret; Goodrich, Amy; Willis, Carl R.; Diehl, Louis F.; Grever, Michael R.; Byrd, John C.; Flinn, Ian W.. "A phase I/ii study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-hodgkin's lymphoma." Annals of Hematology. Vol. 85, no. 5. (January 2006.): 301-307.

Johnson, Amy J.; Lucas, David M.; Muthusamy, Natarajan; Smith, Lisa L.; Edwards, Ryan B.; De lay, Michael D.; Croce, Carlo M.; Grever, Michael R.; Byrd, John C.. "Characterization of the Tcl-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia." Blood. Vol. 108, no. 4. (January 2006.): 1334-1338.

Byrd, John C.; Lin, Thomas S.; Grever, Michael R.. "Treatment of relapsed chronic lymphocytic leukemia: Old and new therapies." Seminars in Oncology. Vol. 33, no. 2. (January 2006.): 210-219.

Liu, Zhongfa; Marcucci, Guido; Byrd, John C.; Grever, Michael; Xiao, Jim; Chan, Kenneth K.. "Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2 '-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method." Rapid Communications in Mass Spectrometry. Vol. 20, no. 7. (January 2006.): 1117-1126.

Chen, Danny; Song, Sae Heum; Wientjes, M. Guillaume; Yeh, Teng Kuang; Zhao, Liang; Villalona-Calero, Miguel; Otterson, Gregory A.; Jensen, Rhonda; Grever, Michael; Murgo, Anthony J.; Au, Jessie L-S.. "Nontoxic suramin as a chemosensitizer in patients: Dosing nomogram development." Pharmaceutical Research (Dordrecht). Vol. 23, no. 6. (January 2006.): 1265-1274.

Gore, Steven D.; Baylin, Stephen; Sugar, Elizabeth; Carraway, Hetty; Miller, Carole B.; Carducci, Michael; Grever, Michael; Galm, Oliver; Dauses, Tianna; Karp, Judith E.; Rudek, Michelle A.; Zhao, Ming; Smith, B. Douglas; Manning, Jasper; Jiemjit, Anchalee; Dover, George; Mays, Abbie; Zwiebel, James; Murgo, Anthony; Weng, Li-Jun; et al.. "Combined Dna methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms." Cancer Research. Vol. 66, no. 12. (January 2006.): 6361-6369.

Grever, Michael R. "Pentostatin: impact on outcome in hairy cell leukemia.." Hematology/oncology clinics of North America. Vol. 20, no. 5. (January 2006.): 1099-108.

Pal, Sharmistha; Baiocchi, Robert, A; Byrd, John, C; Grever, Michael, R; Jacob, Samson, T; Sif, Said. "Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma.." The EMBO journal. Vol. 26, no. 15. (January 2007.): -.

Ali, Naeem, A; O'Brien, James M Jr; Blum, William; Byrd, John, C; Klisovic, Rebecca, B; Marcucci, Guido; Phillips, Gary; Marsh, Clay, B; Lemeshow, Stanley; Grever, Michael R. "Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality.." Cancer. Vol. 110, no. 1. (January 2007.): -.

Motiwala, Tasneem; Majumder, Sarmila; Kutay, Huban; Smith, David Spencer; Neuberg, Donna, S; Lucas, David, M; Byrd, John, C; Grever, Michael; Jacob, Samson T. "Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 13, no. 11. (January 2007.): -.

Hussain, Syed-Rehan, A; Cheney, Carolyn, M; Johnson, Amy, J; Lin, Thomas, S; Grever, Michael, R; Caligiuri, Michael, A; Lucas, David, M; Byrd, John C. "Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 13, no. 7. (January 2007.): -.

Christian, Beth, A; Grever, Michael, R; Byrd, John, C; Lin, Thomas S. "Flavopiridol in the treatment of chronic lymphocytic leukemia.." Current opinion in oncology. Vol. 19, no. 6. (January 2007.): -.

Cheng, Hao; Liu, Zhongfa; Blum, William; Byrd, John, C; Klisovic, Rebecca; Grever, Michael, R; Marcucci, Guido; Chan, Kenneth K. "Quantification of valproic acid and its metabolite 2-propyl-4-pentenoic acid in human plasma using HPLC-MS/MS.." Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. Vol. 850, no. 1-2. (January 2007.): -.

Raval, Aparna; Tanner, Stephan, M; Byrd, John, C; Angerman, Elizabeth, B; Perko, James, D; Chen, Shih-Shih; Hackanson, Bjorn; Grever, Michael, R; Lucas, David, M; Matkovic, Jennifer, J; Lin, Thomas, S; Kipps, Thomas, J; Murray, Fiona; Weisenburger, Dennis; Sanger, Warren; Lynch, Jane; Watson, Patrice; Jansen, Mary; Yoshinaga, Yuko; Rosenquist, Richard; et al.. "Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.." Cell. Vol. 129, no. 5. (January 2007.): -.

Blum, William; Klisovic, Rebecca, B; Hackanson, Bjoern; Liu, Zhongfa; Liu, Shujun; Devine, Hollie; Vukosavljevic, Tamara; Huynh, Lenguyen; Lozanski, Gerard; Kefauver, Cheryl; Plass, Christoph; Devine, Steven, M; Heerema, Nyla, A; Murgo, Anthony; Chan, Kenneth, K; Grever, Michael, R; Byrd, John, C; Marcucci, Guido. "Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 25, no. 25. (January 2007.): -.

Shanafelt, Tait, D; Lin, Thomas; Geyer, Susan, M; Zent, Clive, S; Leung, Nelson; Kabat, Brian; Bowen, Deborah; Grever, Michael, R; Byrd, John, C; Kay, Neil E. "Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia.." Cancer. Vol. 109, no. 11. (January 2007.): -.

Grever, Michael, R; Lucas, David, M; Johnson, Amy, J; Byrd, John C. "Novel agents and strategies for treatment of p53-defective chronic lymphocytic leukemia.." Best practice & research. Clinical haematology. Vol. 20, no. 3. (January 2007.): -.

Grever, Michael, R; Lucas, David, M; Dewald, Gordon, W; Neuberg, Donna, S; Reed, John, C; Kitada, Shinichi; Flinn, Ian, W; Tallman, Martin, S; Appelbaum, Frederick, R; Larson, Richard, A; Paietta, Elisabeth; Jelinek, Diane, F; Gribben, John, G; Byrd, John C. "Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 25, no. 7. (January 2007.): -.

Byrd, John C.; Lin, Thomas S.; Dalton, James T.; Wu, Di; Phelps, Mitch A.; Fischer, Beth; Moran, Mollie; Blum, Kristie A.; Rovin, Brad; Brooker-McEldowney, Michelle; Broering, Sarah; Schaaf, Larry J.; Johnson, Amy J.; Lucas, David M.; Heerema, Nyla A.; Lozanski, Gerard; Young, Donn C.; Suarez, Jose-Ramon; Colevas, A. Dimitrios; Grever, Michael R.. "Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia." Blood. Vol. 109, no. 2. (January 2007.): 399-404.

Browning, Rebekah, L; Geyer, Susan, M; Johnson, Amy, J; Jelinek, Diane, F; Tschumper, Renee, C; Call, Timothy, G; Shanafelt, Tait, D; Zent, Clive, S; Bone, Nancy, D; Dewald, Gordon, W; Lin, Thomas, S; Heerema, Nyla, A; Grever, Michael, R; Kay, Neil, E; Byrd, John, C; Lucas, David M. "Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia.." Leukemia research. Vol. 31, no. 12. (January 2007.): -.

Flinn, Ian, W; Neuberg, Donna, S; Grever, Michael, R; Dewald, Gordon, W; Bennett, John, M; Paietta, Elisabeth, M; Hussein, Mohamad, A; Appelbaum, Frederick, R; Larson, Richard, A; Moore, Dennis F Jr; Tallman, Martin S. "Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 25, no. 7. (January 2007.): -.

Flinn IW, Neuberg DS, Grever MR, Dewald GW, Bennett JM, Paietta EM, Hussein MA, Appelbaum FR, Larson RA, Moore Jr., DF, Tallman MS:. "Phase III Randomized Trial of Fludarabine and Cyclophosphamide versus Fludarabine for Patients with previously untreated Chronic Lymphocytic Leukemia. A U.S. Intergroup Trial (E2997)." J. Clin Oncol. Vol. (7), no. 25. (January 2007.): 793-.

Kay, Neil E.; Geyer, Susan M.; Call, Timothy G.; Shanafelt, Tait D.; Zent, Clive S.; Jelinek, Diane F.; Tschumper, Renee; Bone, Nancy D.; Dewald, Gordon W.; Lin, Thomas S.; Heerema, Nyla A.; Smith, Lisa; Grever, Michael R.; Byrd, John C.. "Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia." Blood. Vol. 109, no. 2. (January 2007.): 405-411.

Blum, Kristie, A; Young, Donn; Broering, Sarah; Lucas, Margaret, S; Fischer, Beth; Lin, Thomas, S; Grever, Michael, R; Byrd, John C. "Computed tomography scans do not improve the predictive power of 1996 national cancer institute sponsored working group chronic lymphocytic leukemia response criteria.." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol. 25, no. 35. (January 2007.): -.

Bekaii-Saab TS; Liu J; Chan KK; Balcerzak SP; Ivy PS; Grever MR; Kraut EH. "A phase I and pharmacokinetic study of weekly oxaliplatin followed by paclitaxel in patients with solid tumors.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 14, no. 11. (June 2008.): 3434-.

Rassenti LZ; Jain S; Keating MJ; Wierda WG; Grever MR; Byrd JC; Kay NE; Brown JR; Gribben JG; Neuberg DS; He F; Greaves AW; Rai KR; Kipps TJ. "Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.." Blood. Vol. 112, no. 5. (September 2008.): 1923-.

Klisovic RB; Blum W; Wei X; Liu S; Liu Z; Xie Z; Vukosavljevic T; Kefauver C; Huynh L; Pang J; Zwiebel JA; Devine S; Byrd JC; Grever MR; Chan K; Marcucci G. "Phase I study of GTI-2040, an antisense to ribonucleotide reductase, in combination with high-dose cytarabine in patients with acute myeloid leukemia.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 14, no. 12. (June 2008.): 3889-.

Johnston JS; Phelps MA; Blum KA; Blum W; Grever MR; Farley KL; Dalton JT. "Development and validation of a rapid and sensitive high-performance liquid chromatography-mass spectroscopy assay for determination of 17-(allylamino)-17-demethoxygeldanamycin and 17-(amino)-17-demethoxygeldanamycin in human plasma.." Journal Of Chromatography. B, Analytical Technologies In The Biomedical And Life Sciences. Vol. 871, no. 1. (August 2008.): 15-.

Hussain SR; Lucas DM; Johnson AJ; Lin TS; Bakaletz AP; Dang VX; Viatchenko-Karpinski S; Ruppert AS; Byrd JC; Kuppusamy P; Crouser ED; Grever MR. "Flavopiridol causes early mitochondrial damage in chronic lymphocytic leukemia cells with impaired oxygen consumption and mobilization of intracellular calcium.." Blood. Vol. 111, no. 6. (March 2008.): 3190-.

Liu Q; Farley KL; Johnson AJ; Muthusamy N; Hofmeister CC; Blum KA; Schaaf LJ; Grever MR; Byrd JC; Dalton JT; Phelps MA. "Development and validation of a highly sensitive liquid chromatography/mass spectrometry method for simultaneous quantification of lenalidomide and flavopiridol in human plasma.." Therapeutic Drug Monitoring. Vol. 30, no. 5. (October 2008.): 620-.

Phelps MA; Rozewski DM; Johnston JS; Farley KL; Albanese KA; Byrd JC; Lin TS; Grever MR; Dalton JT. "Development and validation of a sensitive liquid chromatography/mass spectrometry method for quantitation of flavopiridol in plasma enables accurate estimation of pharmacokinetic parameters with a clinically active dosing schedule.." Journal Of Chromatography. B, Analytical Technologies In The Biomedical And Life Sciences. Vol. 868, no. 1-2. (June 2008.): 110-.

Yang X; Zhao X; Phelps MA; Piao L; Rozewski DM; Liu Q; Lee LJ; Marcucci G; Grever MR; Byrd JC; Dalton JT; Lee RJ. "A novel liposomal formulation of flavopiridol.." International Journal Of Pharmaceutics. Vol. 365, no. 1-2. (January 2009.): 170-.

Su X; Lucas DM; Zhang L; Xu H; Zabrouskov V; Davis ME; Knapp AR; Young DC; Payne PR; Parthun MR; Marcucci G; Grever MR; Byrd JC; Freitas MA. "Validation of an LC-MS based approach for profiling histones in chronic lymphocytic leukemia.." Proteomics. Vol. 9, no. 5. (March 2009.): 1197-.

Lucas DM; Edwards RB; Lozanski G; West DA; Shin JD; Vargo MA; Davis ME; Rozewski DM; Johnson AJ; Su BN; Goettl VM; Heerema NA; Lin TS; Lehman A; Zhang X; Jarjoura D; Newman DJ; Byrd JC; Kinghorn AD; Grever MR. "The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo.." Blood. Vol. 113, no. 19. (May 2009.): 4656-.

Lin TS; Ruppert AS; Johnson AJ; Fischer B; Heerema NA; Andritsos LA; Blum KA; Flynn JM; Jones JA; Hu W; Moran ME; Mitchell SM; Smith LL; Wagner AJ; Raymond CA; Schaaf LJ; Phelps MA; Villalona-Calero MA; Grever MR; Byrd JC. "Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 27, no. 35. (December 2009.): 6012-.

Chen P; Liu Z; Liu S; Xie Z; Aimiuwu J; Pang J; Klisovic R; Blum W; Grever MR; Marcucci G; Chan KK. "A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels.." Pharmaceutical Research. Vol. 26, no. 6. (June 2009.): 1504-.

Shanafelt TD; Byrd JC; LaPLant B; Zent CS; Call T; Secreto C; Grever MR; Lin TS; Kay NE. "Pretreatment angiogenic cytokines predict response to chemoimmunotherapy in patients with chronic lymphocytic leukaemia.." British Journal Of Haematology. Vol. 146, no. 6. (September 2009.): 660-.

Farag SS; Zhang S; Jansak BS; Wang X; Kraut E; Chan K; Dancey JE; Grever MR. "Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.." Leukemia Research. Vol. 33, no. 11. (November 2009.): 1475-.

Bekaii-Saab TS; Roda JM; Guenterberg KD; Ramaswamy B; Young DC; Ferketich AK; Lamb TA; Grever MR; Shapiro CL; Carson WE 3rd. "A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies.." Molecular Cancer Therapeutics. Vol. 8, no. 11. (November 2009.): 2983-.

Christian BA; Grever MR; Byrd JC; Lin TS. "Flavopiridol in chronic lymphocytic leukemia: a concise review.." Clinical Lymphoma & Myeloma. Vol. 9 Suppl 3, (January 2009.): S179-.

Phelps MA; Lin TS; Johnson AJ; Hurh E; Rozewski DM; Farley KL; Wu D; Blum KA; Fischer B; Mitchell SM; Moran ME; Brooker-McEldowney M; Heerema NA; Jarjoura D; Schaaf LJ; Byrd JC; Grever MR; Dalton JT. "Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia.." Blood. Vol. 113, no. 12. (March 2009.): 2637-.

Kane GC; Grever MR; Kennedy JI; Kuzma MA; Saltzman AR; Wiernik PH; Baptista NV. "The anticipated physician shortage: meeting the nation's need for physician services.." The American Journal Of Medicine. Vol. 122, no. 12. (December 2009.): 1156-.

Awan FT; Kay NE; Davis ME; Wu W; Geyer SM; Leung N; Jelinek DF; Tschumper RC; Secreto CR; Lin TS; Grever MR; Shanafelt TD; Zent CS; Call TG; Heerema NA; Lozanski G; Byrd JC; Lucas DM. "Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab.." Blood. Vol. 113, no. 3. (January 2009.): 535-.

Grever MR; Zinzani PL. "Long-term follow-up studies in hairy cell leukemia.." Leukemia & Lymphoma. Vol. 50 Suppl 1, (October 2009.): 23-.

Grever MR. "Dedication to the clinical investigators for their work with hairy cell leukemia.." Leukemia & Lymphoma. Vol. 50 Suppl 1, (October 2009.): 1-.

Kaumaya PT; Foy KC; Garrett J; Rawale SV; Vicari D; Thurmond JM; Lamb T; Mani A; Kane Y; Balint CR; Chalupa D; Otterson GA; Shapiro CL; Fowler JM; Grever MR; Bekaii-Saab TS; Carson WE 3rd. "Phase I active immunotherapy with combination of two chimeric, human epidermal growth factor receptor 2, B-cell epitopes fused to a promiscuous T-cell epitope in patients with metastatic and/or recurrent solid tumors.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 27, no. 31. (November 2009.): 5270-.

Lin TS; Stock W; Xu H; Phelps MA; Lucas MS; Guster SK; Briggs BR; Cheney C; Porcu P; Flinn IW; Grever MR; Dalton JT; Byrd JC. "A phase I/II dose escalation study of apolizumab (Hu1D10) using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemia.." Leukemia & Lymphoma. Vol. 50, no. 12. (December 2009.): 1958-.

Blum W; Phelps MA; Klisovic RB; Rozewski DM; Ni W; Albanese KA; Rovin B; Kefauver C; Devine SM; Lucas DM; Johnson A; Schaaf LJ; Byrd JC; Marcucci G; Grever MR. "Phase I clinical and pharmacokinetic study of a novel schedule of flavopiridol in relapsed or refractory acute leukemias.." Haematologica. Vol. 95, no. 7. (July 2010.): 1098-.

Blum KA; Liu Z; Lucas DM; Chen P; Xie Z; Baiocchi R; Benson DM; Devine SM; Jones J; Andritsos L; Flynn J; Plass C; Marcucci G; Chan KK; Grever MR; Byrd JC. "Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation.." British Journal Of Haematology. Vol. 150, no. 2. (July 2010.): 189-.

Ramaswamy B; Bekaii-Saab T; Schaaf LJ; Lesinski GB; Lucas DM; Young DC; Ruppert AS; Byrd JC; Culler K; Wilkins D; Wright JJ; Grever MR; Shapiro CL. "A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.." Cancer Chemotherapy And Pharmacology. Vol. 66, no. 1. (May 2010.): 151-.

Lucas DM; Still PC; PĂ©rez LB; Grever MR; Kinghorn AD. "Potential of plant-derived natural products in the treatment of leukemia and lymphoma.." Current Drug Targets. Vol. 11, no. 7. (July 2010.): 812-.

Kay NE; Wu W; Kabat B; LaPlant B; Lin TS; Byrd JC; Jelinek DF; Grever MR; Zent CS; Call TG; Shanafelt TD. "Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia.." Cancer. Vol. 116, no. 9. (May 2010.): 2180-.

Dancey JE; Dobbin KK; Groshen S; Jessup JM; Hruszkewycz AH; Koehler M; Parchment R; Ratain MJ; Shankar LK; Stadler WM; True LD; Gravell A; Grever MR. "Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 16, no. 6. (March 2010.): 1745-.

Lin TS; Blum KA; Fischer DB; Mitchell SM; Ruppert AS; Porcu P; Kraut EH; Baiocchi RA; Moran ME; Johnson AJ; Schaaf LJ; Grever MR; Byrd JC. "Flavopiridol, fludarabine, and rituximab in mantle cell lymphoma and indolent B-cell lymphoproliferative disorders.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 28, no. 3. (January 2010.): 418-.

Blum W; Garzon R; Klisovic RB; Schwind S; Walker A; Geyer S; Liu S; Havelange V; Becker H; Schaaf L; Mickle J; Devine H; Kefauver C; Devine SM; Chan KK; Heerema NA; Bloomfield CD; Grever MR; Byrd JC; Villalona-Calero M; Croce CM; Marcucci G. "Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine.." Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 107, no. 16. (April 2010.): 7473-.

Lucas DM; Alinari L; West DA; Davis ME; Edwards RB; Johnson AJ; Blum KA; Hofmeister CC; Freitas MA; Parthun MR; Wang D; Lehman A; Zhang X; Jarjoura D; Kulp SK; Croce CM; Grever MR; Chen CS; Baiocchi RA; Byrd JC. "The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo.." Plos One. Vol. 5, no. 6. (January 2010.): e10941-.

Grever MR. "How I treat hairy cell leukemia.." Blood. Vol. 115, no. 1. (January 2010.): 21-.

Saradhi UV; Gupta SV; Chiu M; Wang J; Ling Y; Liu Z; Newman DJ; Covey JM; Kinghorn AD; Marcucci G; Lucas DM; Grever MR; Phelps MA; Chan KK. "Characterization of silvestrol pharmacokinetics in mice using liquid chromatography-tandem mass spectrometry.." The AAPS Journal. Vol. 13, no. 3. (September 2011.): 347-356.

Gupta SV; Sass EJ; Davis ME; Edwards RB; Lozanski G; Heerema NA; Lehman A; Zhang X; Jarjoura D; Byrd JC; Pan L; Chan KK; Kinghorn AD; Phelps MA; Grever MR; Lucas DM. "Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells.." The AAPS Journal. Vol. 13, no. 3. (September 2011.): 357-364.

Andritsos LA; Grever MR. "Salvage therapy for relapsed chronic lymphocytic leukemia.." Expert Review Of Hematology. Vol. 4, no. 2. (April 2011.): 199-.

Kraut EH; Rhoades C; Zhang Y; Cheng H; Aimiumu J; Chen P; Lang J; Young DC; Agrawal A; Dancey J; Chan KK; Grever MR. "Phase I and pharmacokinetic study of erlotinib (OSI-774) in combination with docetaxel in squamous cell carcinoma of the head and neck (SSCHN).." Cancer Chemotherapy And Pharmacology. Vol. 67, no. 3. (March 2011.): 579-.

Bekaii-Saab T; Phelps MA; Li X; Saji M; Goff L; Kauh JS; O'Neil BH; Balsom S; Balint C; Liersemann R; Vasko VV; Bloomston M; Marsh W; Doyle LA; Ellison G; Grever M; Ringel MD; Villalona-Calero MA. "Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 29, no. 17. (June 2011.): 2357-.

Hofmeister CC, Yang X, Pichiorri F, Chen P, Rozewski DM, Johnson AJ, Lee S, Liu Z, Garr CL, Hade EM, Ji J, schaaf LJ, Benson DM Jr, Kraut EH, Hicks WJ, Chan KK, chen CS, Farag SS, Grever MR, Byrd JC, Phelps MA. "PHase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: Evidence for lenalidomide-CCI-779 interaction via P-glycoprotein." J clin Oncol. no. [Epub ahead of print]. (August 2011.): -.

Blum KA, Ruppert AS, Woyach JA, Jones JA, Andritsos L, Flynn JM, Rovin B, Villalona-Calero M, Ji J, Phelps M, Johnson AJ, Grever MR, Byrd JC. "Risk factors for tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with the cyclin-dependent kinase inhibitor, flavopiridol." Leukemia. no. [Epub ahead of print]. (May 2011.): -.

Kreitman RJ; Polliack A; Grever M. "Treatment of hairy cell leukemia in its second half-century: an International Conference on Hairy Cell Leukemia at the National Institutes of Health, April 26-27, 2010, Bethesda, MD.." Leukemia & Lymphoma. Vol. 52 Suppl 2, (June 2011.): 1-.

Grever MR. "Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.." Leukemia & Lymphoma. Vol. 52 Suppl 2, (June 2011.): 25-28.

Smith MR, Neuberg D, Flinn IW, Grever MR, Lazarus HM, Rowe JM, Dewald G, Bennett JM, Paietta EM, Byrd JC, Hussein MA, Appelbaum FR, Larson RA, Litzow MR, Tallman MS. "Incidence of therapy-related myeloid neoplasia after initial therapy for CLL with fludarabine-cyclophosphamide versus fludarabine: long-term follow-up of US intergroup study E2997." Blood. no. [Epub ahead of print]. (July 2011.): -.

 

Presentations

"Stohlman Lectureship." Presented at Tufts University, Boston, MA, US|USA. (April 2000)

"Chronic Lymphocytic Leukemia." Presented at Cleveland Clinic Foundation, Cleveland, OH, US|USA. (April 2002)

"Chronic Lymphocytic Leukemia." Presented at NEOUCOM Northeastern Ohio Universities, Rootstown, OH, US|USA. (May 2002)

"Chronic Lymphocytic Leukemia." Presented at Allen Zieger Symposium, Novi, MI, US|USA. (November 2003)

"Experimental Therapeutics and Anti-cancer Agents." Presented at NCI Biotherapy of Cancer Symposium, Munich, DE|DEU. (September 2003)

"Achievements in Cancer Drug Development." Presented at NCI President's Cancer Panel, Columbus, OH, US|USA. (January 2004)

"Creating a Synergistic Action Plan." Presented at Roundtable Discussion, Johns Hopkins Workshop on Clinical Targeting of Epigenetic Changes in Cancr Therapeutics, Charleston, SC. (January 2005)

"Overview of OSU Cancer Research Projects." Presented at Ohio State Medical Association Annual Meeting, Dublin, OH. (October 2005)

"Drug Discovery and Development." Presented at NIH/NCI 5oth Anniversary of Developmental Therapeutics Program, Bethesda, MD. (November 2005)

"American Society of Hematology Update." Presented at Leukemia and Lymphoma Society Meeting, Baltimore, MD. (February 2006)

"Molecular and Genetic Biomarkers in CLL - Opportunityfor Innovative Therapy." Presented at 3rd Canadian National Meeting for CLL, Winnipeg, MB, CA|CAN. (October 2007)

"Hairy Cell Leukemia." Presented at International Hairy Cell Leukemia Conference, Chicago, IL. (October 2007)

"Biomarkers in Cancer Clinical Trials." Presented at American Association for Cancer Research, Los Angelos, CA. (April 2007)

"Session on Pharmacodynamics Biomarkers." Presented at 7th International Workshop on Pharmacodynamics of Anti-Cancer Agents, CR|CRI. (September 2007)

"Update on CLL." Presented at 2008 Western Canadian Lymphoproliferative Disorders, Banff, CA|CAN. (April 2008)

"Drug Development in Hairy Cell Leukemia." Presented at International Hairy Cell Leukemia Meeting, Marlow, GB|GBR. (May 2008)

"Use of Biomarkers in Drug Development." Presented at NCI Meeting, Chicago, IL. (July 2008)

"Phase I Trials of Anit-Cancer Agents: The Ohio State University." Presented at 2009 NCI Translational Science Meeting, Vienna, VA. (November 2009)

"Where are we going in the field of CLL?." Presented at First Global Panel on CLL, New Orleans, LA. (December 2009)

"Hairy Cell Leukemia: A Successful Model for Experimental Therapeutics in Orphan Diseases." Presented at IACRLRD Symposium XXIV, Columbus, OH. (October 2009)

"Advancements in Therapy for Leukemia, Lymphoma, and Multiple Myeloma." Presented at Leukemia and Lymphoma Society Monthly Lecture Series for Patients and Caregivers, Lima, OH. (May 2011)

 

Professional Activities

2010 - present APSA Midwest Regional Meeting panel discussion. American Physician Scientists Association. Columbus, OH.
2011 - present Cancer Drug Development Roundtable. The Ohio State University Comprehensive Cancer Center. Columbus, OH.