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Robert Baiocchi, MD, PhD


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B404 Starling Loving Hall
320 West 10th Avenue
Columbus, OH 43210

Phone: (614) 685-5667

Email: baiocchi.1@osu.edu

 

Current OSU Appointments

Associate Professor, Hematology

Physician, FGP-Hematology

 

Advising Narrative

Roessler Scholar 2006-2007; American College of Physicians, (OH Chapter) 4th place Basic Research Presentation. Senior Honors Thesis granted 6/06; Senior Research Scholar Summer 2006, Presidents' Salute for Undergraduate Academic Achievment 5/07; Denman Research Forum: 2nd Place Medical Sciences. Mayers Scholarship Summer 2006; TELR Scholar OSU 2006; Denman Research Forum: 1st Place Biological Sciences. Senior Research Scholar Summer 2006; Best Poster Biological Sciences Undergraduate Colloquium 2007; Denman Research Forum: 3rd Place Biological Sciences. Senior Honors Thesis granted 5/10; Arts and Sciences Undergraduate Research Scholarship Recipient 5/08; Presidents' Salute for Undergraduate Academic Achievement 5/10; Biological, Mathematical and Physical Sciences; BMPS Undergraduate Research Forum: Best Poster; Denman Research Forum: 2nd Place Health Professions - Laboratory/Cellular 5/10, 2011 Roessler Scholar Senior Honors Thesis 2005 Grever Summer Program for Biomedical Sciences, 2008; Phi Kappa Phi Undergraduate Enrichment Award 2008 2009 OSU Undergraduate Research Scholarship2010 Denman2010 ASH Trainee Research Award2010-2011 Pelotonia Undergraduate Fellowship 6/07 Senior Honors Thesis granted 2006 Senior Research Scholar Summer 5/07 Presidents' Salute for Undergraduate Academic Achievment 2007 Denman Research Forum: 2nd Place Medical Sciences.2010-2011 Roessler Scholar Senior Honors Thesis granted 6/06; Senior Research Scholar Summer 2006, Presidents' Salute for Undergraduate Academic Achievment 5/07; Denman Research Forum: 2nd Place Medical Sciences.2010 Internal Medicine Summer Research Program; 2010 Peletonia Medical Student Scholar OSU Undergraduate Research Scholarship 2009, Presidential Salute 2010 2009 OSU Undergraduate Research Scholarship 5/07 Presidents' Salute for Undergraduate Adademic Achievement2010 Denman Research Forum: 2nd Place Medical Sciences 2011 The Ohio State University Honors and Scholars Research Scholarhship, 2011 The Ohio State University Arts and Sciences Research Scholarship, 2011 Solar Foundation Research Grant 2011Stanford University MS Bioengineering2011 University of California at San Francisco Medical School 2011-12Undergraduate Research Scholarship Award, The Ohio State University, Arts and Sciences Honors Program

Roessler Scholar 2006-2007; American College of Physicians, (OH Chapter) 4th place Basic Research Presentation. Senior Honors Thesis granted 6/06; Senior Research Scholar Summer 2006, Presidents' Salute for Undergraduate Academic Achievment 5/07; Denman Research Forum: 2nd Place Medical Sciences. Mayers Scholarship Summer 2006; TELR Scholar OSU 2006; Denman Research Forum: 1st Place Biological Sciences. Senior Research Scholar Summer 2006; Best Poster Biological Sciences Undergraduate Colloquium 2007; Denman Research Forum: 3rd Place Biological Sciences. Senior Honors Thesis granted 5/10; Arts and Sciences Undergraduate Research Scholarship Recipient 5/08; Presidents' Salute for Undergraduate Academic Achievement 5/10; Biological, Mathematical and Physical Sciences; BMPS Undergraduate Research Forum: Best Poster; Denman Research Forum: 2nd Place Health Professions - Laboratory/Cellular 5/10, 2011 Roessler Scholar Senior Honors Thesis 2005 Grever Summer Program for Biomedical Sciences, 2008; Phi Kappa Phi Undergraduate Enrichment Award 2008 2009 OSU Undergraduate Research Scholarship2010 Denman2010 ASH Trainee Research Award2010-2011 Pelotonia Undergraduate Fellowship 6/07 Senior Honors Thesis granted 2006 Senior Research Scholar Summer 5/07 Presidents' Salute for Undergraduate Academic Achievment 2007 Denman Research Forum: 2nd Place Medical Sciences.2010-2011 Roessler Scholar Senior Honors Thesis granted 6/06; Senior Research Scholar Summer 2006, Presidents' Salute for Undergraduate Academic Achievment 5/07; Denman Research Forum: 2nd Place Medical Sciences.2010 Internal Medicine Summer Research Program; 2010 Peletonia Medical Student Scholar OSU Undergraduate Research Scholarship 2009, Presidential Salute 2010 2009 OSU Undergraduate Research Scholarship 5/07 Presidents' Salute for Undergraduate Adademic Achievement2010 Denman Research Forum: 2nd Place Medical Sciences 2011 The Ohio State University Honors and Scholars Research Scholarhship, 2011 The Ohio State University Arts and Sciences Research Scholarship, 2011 Solar Foundation Research Grant 2011Stanford University MS Bioengineering2011 University of California at San Francisco Medical School 2011-12Undergraduate Research Scholarship Award, The Ohio State University, Arts and Sciences Honors Program

Academic Advising

2006 - present Lapo Alinari The Ohio State University.
2007 - present The Ohio State University.
2008 - present Ludmilla K The Ohio State University.
2008 - present Elaine Cutler The Ohio State University.
2009 - present Rebecca Rieck The Ohio State University.
2009 - present Kate Gordon The Ohio State University.
2004 - 2005 Stephanie Wright The Ohio State University. Graduated 2005. Epigenetic modulation of the UL97 gene product in CMV associated CNS tumors
2005 - 2006 Theresa Lin The Ohio State University.
2005 - 2007 Christian Earl The Ohio State University.
2005 - 2007 Christian Tyler The Ohio State University. Graduated 2006. The role of PRMT5 in high grade astrocytomas
2006 - 2009 Rohit Tiwari The Ohio State University. Design of Nucleoside Analogues to Target Herpes Virus Thymidine Kinase
2007 - 2009 Claudia Chou The Ohio State University.
2008 - 2009 Anna Wolfson The Ohio State University.
2009 Mohamad Algothani The Ohio State University.
2008 - 2010 Ene Raig The Ohio State University. Differential expression of micro RNAs in melanoma
2009 - 2010 Karen Lin The Ohio State University.
2009 - 2011 Mark Lustberg The Ohio State University.
 

Books

Baiocchi, RA. Cytokine regulation of Epstein-Barr virus associated lymphoproliferative disease in the severe combined immune deficient mouse-human chimeric model.. State University of New York at Buffalo, January 1994.

 

Certifications

1997 - present Board Certification: National Board of Medical Examiners
1999 - present Board Certification: National Board of Medical Examiners
2000 - present Board Certification: National Board of Medical Examiners
2001 - present Medical License: State Medical Board of Ohio
2003 - present Board Certification: American Board of Internal Medicine
2009 - present Board Certification: American Board of Internal Medicine
 

Chapters in Books

Robert Baiocchi, Pierluigi Porcu, Thomas Gross. "Immundeficiency Associated Lymphomas." In Non Hodgkins Lymphoma. Edited by James Armitage. -. Philadelphia, PA, US|USA: Lippincott Williams & Wilkins, January 2009.

 

Conferences

Villalona-Calcero M, Stewart C, Baiocchi RA, Caligiuri MA, Foon KA. "Phenotypic characteristics of "prolymphocytoid" transformmed (CLL/PLL) chronic lymphocytic leukemia (CLL) cells." In Journal of Clinical Oncology. (May 1991). Abstract-.

Baiocchi,R,A; Caligiuri,M,A. "LOW-DOSE IL-2 PREVENTS THE DEVELOPMENT OF EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOPROLIFERATIVE DISORDER IN THE SCID-HUMAN MOUSE." In BLOOD. (November 1993). A385-A385.

Baiocchi RA, Sullivan L, Tan J, Narula S, and Caliguiri MA. "Epstein-barr virus-associted lymphoproliferative disease (EBV-LPD) in the severe combined immune deficient human/mouse model: Prevention with low-dose interleukin-2 supresses production of human interleukin-6 and interleukin-10." In Journal of Clinical Oncology. (January 1994). Abstract-.

Baiocchi RA, Haldar S, Sullivan L, Tan JC, Seiden MV, Narula SK, and Caligiuri MA. "Human IL-10 and BCL-2 are abberantly expressed in severe combined immune deficient mouse/human chimeras with Epstein Barr virus lymphoproliferative disease." In Journal of Clinical Oncology. (January 1994). Abstract-.

Carson WE, Haldar S, Baiocchi RA, and Caligiuri MA. "The c-kit ligand suppresses apoptosis of human natural killer cells in serum-free media through the upregulation of BCL 2." In Clinical Cancer Research. (January 1994). Abstract-.

Baiocchi,R,A; Khatri,V; Lindemann,M,I; Ross,M,E; Caprio,A,I; Caprio,T,V; Fenstermaker,R; Bernstein,Z,P; Caligiuri,M,A. "Analysis of FAS/CD95 expression and function in Epstein-Barr virus (EBV)-associated human B cell tumors.." In BLOOD. (November 1996). 1509-1509.

Khatri,V,P; Baiocchi,R,A; Bernstein,Z,P; Caligiuri,M,A. "Lymphomagenesis in the severe combined immune deficient mouse engrafted with human lymphocytes: Clues towards the pathogenesis and treatment of AIDS lymphoma (review)." In ONCOLOGY REPORTS. (January 1997). 241-246.

Khatri,V,P; Yu,F; Baiocchi,R,A; Shah,M,H; Zwerling,B,H; Gould,M; Bernstein,Z,P; Caligiuri,M,A. "Analysis of T(H)1/T(H)2 cytokine gene profile during low dose IL-2 therapy in patients with AIDS or AIDS lymphoma.." In JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. (April 1997). 99-99.

Baiocchi,R,A; Lindemann,M,J; Nordone,P; Caligiuri,M,A. "Combination cytokine therapy prevents human EBV-associated lymphoproliferative disease (EBV-LPD) in the human-PBL-SCID mouse model: Critical role of human natural killer (NK) cells.." In BLOOD. (November 1997). 2279-2279.

Khatri,V,P; Baiocchi,R,A; Bernstein,Z,P; Caligiuri,M,A. "Immunotherapy with low-dose interleukin-2: Rationale for prevention of immune-deficiency-associated cancer." In CANCER JOURNAL. (December 1997). S128-S136.

Khatri V,Baiocchi RA, and Caligiuri MA. "A successful endogenous human immune response to transplantation-associated Epstein-barr virus (EBV) monoclonal B-cell lymphoma." In Annals of Surgical Oncology. (January 1997). Abstract-.

Carrodeguas,L; Baiocchi,R,A; Roychowdhury,S; Peng,R,Q; Orosz,C,G. "The combination of rituximab (anti-CD20 mAb) and daily low dose interleukin-2 (IL-2) therapy effectively treats established human Epstein-Barr virus-associated lymphoproliferative disorder (EBV-LPD) in a mouse model of human EBV-LPD.." In BLOOD. (November 1999). 90A-90A.

Baiocchi RA, Peng R, Schmalbrock P, Moeschberger M, Barth R, and Caligiuri MA. "An in vivo model to evaluate an effective antiviral regimen in Epstein-barr virus (EBV)-associated primary central nervous system lymphoma." In Annals of Oncology. (June 1999). Abstract-.

Shah,M,H; Baiocchi,R,A; Fehniger,T,A; Khatri,V,P; Gould,M; Poiesz,B; Bernstein,Z,P; Caligiuri,M,A. "Cytokine replacement in patients with HIV-1 non-Hodgkin's lymphoma: The rationale for low-dose interleukin-2 therapy." In CANCER JOURNAL. (February 2000). S45-S51.

Baiocchi,R,A; Vourganti,S; Sekula,T; Nair,V; Roychowdhury,S; Marcucci,G; Nuovo,G; Parthun,M; Byrd,J; Grever,M; Caligiuri,M. "Treatment of EBV-transformed B cell lines with depsipeptide results in the induction of a viral thymidine kinase and enhanced susceptibility to antiviral-induced apoptosis.." In CLINICAL CANCER RESEARCH. (November 2001). 3772S-3772S.

Porcu P, Pelletier RP, Davies EA, Baiocchi RA, Eisenbies CF, Roychowdhury S, Nuovo GJ, Marsh W, Vanbuskirk A, Henry ML, Ferguson RM, and Caliguiri MA. "Post-transplant lymphoproliferative disorders following renal allografting: prospective immunological and molecular monitoring identifies correlates of clinical response to reduction of immune suppression and antiviral therapy." In Clinical Cancer Research. (April 2001). Abstract-.

Roychowdhury,S; Baiocchi,R,A; Vourganti,S; Bhatt,D; Chou,J,D; Eisenbeis,C,F; Grever,M,R; Caligiuri,M,A. "The histone deacetylase inhibitor depsipeptide (FR901228) selectively induces apoptosis in latency type III Epstein-Barr virus (EBV) transformed lymphoblastoid cells (LCL) and is enhanced by the inhibition of NFkappaB.." In BLOOD. (November 2002). 780A-781A.

Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Chou JD, Eisenbeis CF, Grever MR, and Caligiuri MA. "Combination Antiviral therapy to treat Epstein-barr virus-associated promary central nervous system lymphoma." In Journal of Clinical Oncology. (January 2002). Abstract-.

VanBuskirk,A,M; Hoppes,T,C; Ferketich,A,K; Rowchowdhury,S; Baiocchi,R. "IFN-gamma genotype and TGF-beta interactions contribute to EBV-associated lymphoproliferative disorder (EBV-LPD) development." In AMERICAN JOURNAL OF TRANSPLANTATION. (January 2004). 447-447.

Freud,A,G; Becknell,B; Roychowdhury,S; Mao,H,C; Ferketich,A,K; Nuovo,G,J; Hughes,T,L; Marburger,T,B; Sung,J; Baiocchi,R,A; Guimond,M; Caliguri,M,A. "A novel human CD34(+) subset that constitutively expresses the high affinity interleukin-2 receptor traffics to lymph nodes and differentiates into CD56(Bright) natural killer cells.." In BLOOD. (November 2004). 93A-93A.

Porcu,P; Baiocchi,R; Buckner,M; Byrd,J,C; Magro,C,M. "Bexarotene-induced T-cell immunomodulation and response in CTCL.." In BLOOD. (November 2004). 213A-213A.

Porcu,P; Mone,A; Puhalla,S; Whitman,S; Baiocchi,R; Caligiuri,M; Byrd,J. "Durable complete response (CR) and suppression of the human T-cell leukemia virus (HTLV-1) viral load (VC) with alemtuzumab in refractory adult T-cell leukemia (ATL).." In JOURNAL OF CLINICAL ONCOLOGY. (June 2005). 594S-594S.

Wadehra,N; Lin,T; Ryan,T; Schneider,A; Pepple,A; Johnston,J; Dalton,J; Banks,A; Eisenbeis,C,R; Lai,R; Byrd,J,C; Blum,K; Baiocchi,R,A. "Combination bortezomib (PS341, Velcade) and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma.." In BLOOD. (November 2005). 677A-677A.

Grady T, Nelson M, Staub A, Tucker M,Baiocchi RA, Nuovo G, Magro C, and Porcu P. "Elevated peripheral blood (PB) cytomegalovirus (CMV) viral loads and reduced CD8* t-cell counts are common findings in T-cell lymphomas before systemic therapy." In Blood. (December 2005). Abstract 2822-.

Porcu,P; Baiocchi,R,A; Lee,J; Lin,T,S; Blum,K; Grady,T; Grever,M,R; Byrd,J,C. "Phase I trial of subcutaneous (SQ) alemtuzumab (A) and CHOP in T-cell lymphoma: Preliminary results.." In JOURNAL OF CLINICAL ONCOLOGY. (June 2006). 445S-445S.

Liu,Shujun; Pang,Jiuxia; Yu,Jianhua; Liu,Zhongfa; Huynh,LeNguyen; Kearney,Jessica; Paschka,Peter; Klisovic,Rebecca,B; Baiocchi,Robert; Blum,William; Perrotti,Danilo; Marcucci,Guido. "Bortezomib-induced down-regulation of KIT is mediated by inhibition of Sp1 and NF-kB in AML1/ETO-positive cells.." In BLOOD. (November 2006). 132B-132B.

Blum,Kristie,A; Lucas,Margaret,S; Johnston,Jeffrey,S; Dalton,James; Young,Donn; Baiocchi,Robert,A; Lin,Thomas,S; Porcu,Pierluigi; Byrd,John,C. "Excessive neurotoxicity in a phase II trial of combined bortezomib and rituximab in patients with relapsed/refractory mantle cell (MCL) and follicular (FL) non-Hodgkin's lymphoma.." In BLOOD. (November 2006). 784A-784A.

Roda,Julie,M; Lapalombella,Rosa; Baiocchi,Robert; Zhukocsky,Eugene; Desjarlais,John; Muthusamy,Natarajan; Byrd,John,C. "Pre-clinical activity of a novel Fc gamma RIIIa engineered CD19 monoclonal antibody in B cell chronic lymphocytic leukemia and acute lymphoblastic leukemia." In BLOOD. (November 2007). 695A-695A.

Porcu,Pierluigi; Baiocchi,Robert,A; Lin,Thomas,S; Blum,Kristie,A; Curtis,Patricia; Michael,Grever,R; Byrd,John,C. "A phase I trial of subcutaneous (SQ) dose-escalated alemtuzumab in patients with T-Cell lymphoproliferative disorders (T-LPD)." In BLOOD. (November 2007). 1001A-1001A.

Porcu P, Baiocchi RA, Liu T, Caligiuri MA. "A vaccine-based strategy to enhance Epstein Barr Virus (EBV)-specific T-cell responses to prevent post-transplant lymphoproliferative disorder (PTLD)." In Journal of Clinical Investigation. (April 2007). Abstract-.

Lin,Thomas,S; Fischer,Beth; Blum,Kristie,A; Porcu,Pierluigi; Kraut,Eric,H; Baiocchi,Robert,A; Moran,Mollie,E; Mitchell,Sarah; Grever,Michael,R; Byrd,John,C. "Flavopiridol, Fludarabine and Rituximab (FFR): An Active Regimen in Indolent B-Cell Lymphoproliferative Disorders and Mantle Cell Lymphoma." In BLOOD. (November 2008). 557-558.

Alinari,Lapo; Hertlein,Erin; Goldenberg,David,M; Lapalombella,Rosa; Yan,Fengting; Zhang,Xiaoli; Lucas,David,M; Muthusamy,Natarajan; Byrd,John,C; Baiocchi,Robert,A. "Combination Anti-CD74 (Milatuzumab) and CD20 (Rituximab) Monoclonal Antibody Therapy Has in Vitro and in Vivo Activity in Mantle Cell Lymphoma." In BLOOD. (November 2008). 327-327.

Blum,Kristie,A; Liu,Zhongfa; Lucas,David,M; Baiocchi,Robert; Lin,Thomas,S; Benson,Don; Devine,Steven,M; Jones,Jeffrey; Andritsos,Leslie; Flynn,Joseph; Cheng,Ping; Xic,Zhiliang; Marcucci,Guido; Chan,Kenneth,K; Grever,Michael,R; Byrd,John,C. "A Phase I Evaluation of Low Dose Decitabine Targeting DNA Hypermethylation in Patients with Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL): Dose-Limiting Myelosuppression without Evidence of Hypomethylation." In BLOOD. (November 2008). 1087-1087.

Blum,Kristie,A; Baiocchi,Robert,A; Alinari,Lapo; Lin,Thomas,S; Porcu,Pierluigi; Jones,Jeffrey; Flynn,Joseph; Hicks,William; Lucas,Margaret,S; Wei,Lai; Johnston,Jeffrey,S; Byrd,John,C. "A Phase II Trial of Induction Plus Maintenance Rituximab and Bortezomib in Patients with Relapsed/Refractory Mantle Cell (MCL) and Follicular (FL) Non-Hodgkin's Lymphoma." In BLOOD. (November 2008). 1049-1050.

Hamadani,M; Baiocchi,R; Lin,T; Blum,K,A; Ezzone,S; Benson,D,M; Devine,S,M; Arthur,G. "FEASIBILITY OF ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION (ALLO-SCT) FOLLOWING REDUCED INTENSITY CONDITIONING (RIC) IN HIV plus PATIENTS WITH HEMATOLOGICAL MALIGNANCIES." In BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. (February 2009). 113-113.

Awan,Farrukh; Lapalombella,Rosa; Trotta,Rossana; Butchar,Jonathan,P; Yu,Bo; Benson,Don; Cheney,Carolyn; Mo,Xiaokui; Lehman,Amy; Jones,Jeffrey,Alan; Flynn,Joseph,M; Jarjoura,David; Baiocchi,Robert,A; Desjarlais,John; Tridandapani,Susheela; Caligiuri,Michael,A; Muthusamy,Natarajan; Byrd,John,C. "CD19 Targeting of Lymphoid Malignancies by Novel Fc-Domain Engineered Monoclonal Antibody." In BLOOD. (November 2009). 1435-1435.

Liu T, Wen J, House M, Clark R, Baiocchi RA, Caliguiri MA. "Defining a novel vaccine strategy for Epstien-barr virus-associated post-transplant lymphoproliferative disorder." In Clinical Cancer Research. (April 2009). Abstract-.

Benson D, Chandler J, Mishra A, Baiocchi RA, Yu J, Liu T, Lozenski G, Porcu P, Devine S, Rotem-Yehudar R, Caliguiri M. "CT-011, a monoclonal PD-1 blocking antibody, enhances natural killer cell activation and cytotoxicity against multiple myeloma." In Clinical Cancer Research. (April 2009). Abstract-.

Alinari,Lapo; Liu,Qing; Chen,Ching-Shih; Yan,Fengting; Dalton,James,T; Lapalombella,Rosa; Zhang,Xiaoli; Lin,Teresa; Byrd,John,C; Baiocchi,Robert,A; Muthusamy,Natarajan. "FTY720 Demonstrates Promising in-Vitro and in-Vivo Pre-Clinical Activity by Down-Modulation of Cyclin D1 and Pakt in Mantle Cell Lymphoma." In BLOOD. (November 2009). 1436-1436.

Alinari,Lapo; Christian,Beth; Yu,Bo; Shin,Jungook; Hertlein,Erin,K; Lapalombella,Rosa; Yan,Fengting; Lesinski,Gregory; Zhang,Xiaoli; Lozanski,Gerard; Muthusamy,Natarajan; Goldenberg,David,M; Byrd,John,C; Baiocchi,Robert,A. "Co-Treatment with Milatuzumab (Anti-CD74 mAb) and Rituximab (Anti-CD20 mAb) Results in the Induction of Mantle Cell Lymphoma Cell Death That Is Dependent On Actin Polymerization and Inhibition of NF-Kb.." In BLOOD. (November 2009). 675-675.

Ramaswamy,B; Phelps,M; Baiocchi,R; Bekaii-Saab,T; Wilkins,D; Arbogast,D; Campbell,A; Doyle,A,L; Grever,M; Shah,M. "A phase I study of flavopiridol using an alternative schedule in patients (pts) with advanced solid tumors." In JOURNAL OF CLINICAL ONCOLOGY. (May 2009). Abstract-.

Liu,Shujun; Wu,Lai,Chu; Pang,Jiuxia; Santhanam,Ramasamy; Schwind,Sebastian; Wu,Yue-Zhong; Hickey,Christopher; Yu,Jianhua; Mishra,Anjali; Becker,Heiko; Li,Chenglong; Briesewitz,Roger; Baiocchi,Robert,A; Chan,Kenneth,K; Caligiuri,Michael,A; Byrd,John,C; Perrotti,Danilo; Garzon,Ramiro; Marcucci,Guido. "Evidence of MicroRNA-29b and Sp1/NF kappa B-HDAC Regulatory Network for KIT Expression in KIT-Driven Acute Myeloid Leukemia (AML): Biologic and Therapeutic Implications." In BLOOD. (November 2009). 387-387.

Mahasenan,Kiran,V; Yan,Fengting; Baiocchi,Robert; Li,Chenglong. "Structure-based computational design of selective, small molecule PRMT5 inhibitors for experimental therapeutics of cancer: Protein modeling, virtual screening and lead validation." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (August 2010). Abstract-.

Jones,Jeffrey,A; Andritsos,Leslie; Baiocchi,Robert; Benson,Don,M; Blum,Kristie,A; Christian,Beth; Deam,Deidre; Flynn,Joseph,M; Johnson,Amy,J; Phelps,Mitch,A; Porcu,Pierluigi; Byrd,John,C; Grever,Michael,R. "Flavopiridol Can Be Safely Administered Using a Pharmacologically Derived Schedule and Demonstrates Activity In Relapsed and Refractory Non-Hodgkin's Lymphoma." In BLOOD. (November 2010). 1169-1169.

Baiocchi,Robert,A; Flynn,Joseph,M; Jones,Jeffrey,A; Blum,Kristie,A; Hofmeister,Craig,C; Poon,Jennifer; Small,Karen; Statkevich,Paul; Grever,Michael,R; Bannerji,Rajat; Byrd,John,C. "Early Evidence of Anti-Lymplioma Activity of the Cyclin Dependent Kinase Inhibitor Dinaciclib (SCH 727965) In Heavily Pre-Treated Low Grade Lymphoma and Diffuse Large Cell Lymphoma Patients." In BLOOD. (November 2010). 1618-1618.

Christian,Beth; Alinari,Lapo; Earl,Christian,Tyler; Wilding,Emily; Quinion,Carl; Lustberg,Mark; Benson,Don,M; Jones,Jeffrey,A; Byrd,John,C; Wegener,William,A; Goldenberg,David,M; Baiocchi,Robert,A; Blum,Kristie,A. "A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma." In BLOOD. (November 2010). 1148-1149.

Yan,Fengting; Smith,Porsha; Alinari,Lapo; Ryu,John; Yu,Bo; Karkhanis,Vrajesh; Tae,Sookil; Patton,John,T; Wilding,Emily,E; Gordon,Kate; Mahasenan,Kiran; Bhasin,Deepak; Agostinelli,Claudio; Pileri,Stefano,A; Byrd,John,C; Sif,Said; Li,Pui-Kai; Li,Chenglong; Baiocchi,Robert,A. "Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma." In BLOOD. (November 2011). 274-274.

Patton,John,T; Lustberg,Mark,E; Garman,Sabrina,L; Kinghorn,A,Douglas; Pan,Li; Lucas,David,M; Grever,Michael,R; Baiocchi,Robert,A. "Silvestrol Modulates Direct Anti-Tumor Activity Against Epstein-Barr Virus (EBV)-Associated Lymphomas While Sparing Innate and Antigen Specific Adaptive Immunity." In BLOOD. (November 2011). 50-51.

Martin,Ludmila,Katherine; Lustberg,Mark,E; Yan,Fengting; Patton,John,T; Porcu,Pierluigi; Nuovo,Gerard; Cavaliere,Robert; Baiocchi,Robert,A. "Successful Treatment of Primary Central Nervous System Post-Transplant Lymphoproliferative Disorder (PCNS-PTLD) with Zidovudine (AZT), Ganciclovir (GCV), Rituximab and Dexamethasone: A Single-Institution Case Series." In BLOOD. (November 2011). 1322-1323.

Alinari L, Edwards R, Prince C, Towns W, Mani R, Lehman A, Zhang X , Jarjoura D, Pan L, Kinghorn AD, Grever MR, Baiocchi RA, Lucas DM. "Blood (ASH Annual Meeting Abstract) Abstract # 3498 Oral Presentation." In Blood. (December 2011). Abstract # 3498-.

Alinari,Lapo; Edwards,Ryan,B; Prince,Courtney,J; Towns,William,H; Mani,Rajeswaran; Lehman,Amy; Zhang,Xiaoli; Jarjoura,David; Pan,Li; Kinghorn,A,Douglas; Greyer,Michael,R; Baiocchi,Robert,A; Lucas,David,M. "Targeting the Cyclin D-CDK4/6-Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol." In BLOOD. (November 2011). 1492-1492.

Cohen,Jonathon,B; Hall,Nathan; Ruppert,Amy,S; Jones,Jeffrey,A; Porcu,Pierluigi; Baiocchi,Robert,A; Penza,Sam; Benson,Don,M; Andritsos,Leslie,A; Flynn,Joseph,M; Devine,Steven,M; Blum,Kristie,A. "The Prognostic Value of FDG PET/CT Prior to Autologous Stem Cell Transplant in Mantle Cell Lymphoma." In BLOOD. (November 2011). 1345-1346.

Christian,Beth; Alinari,Lapo; Jones,Jeffrey,A; Benson,Don,M; Flynn,Joseph,M; Porcu,Pierluigi; Lustberg,Mark,E; Phelps,Mitchell; Poi,Ming; Chung,Diana; Quinion,Carl; Byrd,John,C; Wegener,William; Goldenberg,David,M; Baiocchi,Robert,A; Blum,Kristie,A. "Results of A Phase 1 Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma." In BLOOD. (November 2011). 1584-1584.

Alinari L, Mahoney E, Patton JT, Zhang X, Huynh L, Earl CT, Mani R, Mao Y, Yu B, Towns WH, Chen C-S, Goldenberg DM, Blum KA, Byrd JC, Muthusamy N, Prætorius-Ibba M, Baiocchi RA. "FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death." In Blood. (December 2011). Abstract #600-.

Welliver,Meng,X; Salem,Galena; Ruppert,Amy,S; Otto,Bradley,A; Baiocchi,Robert,A; Porcu,Pierluigi. "Utilization of EBV DNA Copy Number Monitoring in Extranodal NK Lymphoma, Nasal Type in Non Asian Patients." In BLOOD. (November 2012). Abstract-.

Otterson,G,A; Wu,X; Welliver,M; Sharma,S; Shilo,K; Hitchcock,C; Li,C; Baiocchi,R. "PRMT5, a Novel Epigenetic Target in Lung Cancers." In EUROPEAN JOURNAL OF CANCER. (November 2012). 171-171.

Hofmeister,Craig,C; Liu,Zhongfa; Bowers,Mindy,A; Porcu,Pierluigi; Flynn,Joseph,M; Christian,Beth; Baiocchi,Robert,A; Benson,Don,M; Andritsos,Leslie,A; Greenfield,Carli,N; Sell,Megan; Geyer,Susan; Byrd,John,C; Grever,Michael,R. "Phase I Study of AR-42 in Relapsed Multiple Myeloma and Lymphoma.." In BLOOD. (November 2012). Abstract-.

Alinari,Lapo; Yan,Fengting; Smith,Porsha; Patton,John,T; Quinion,Carl; Yu,Bo; Earl,Christian,Tyler; Lustberg,Mark,E; Villagomez,Lynda; Hertlein,Erin,K; Byrd,John,C; Ayers,Leona; Motiwala,Tasneem; Majumder,Sarmila; Li,Chenglong; Sif,Said; Jacob,Samson,T; Baiocchi,Robert,A. "Protein Arginine Methyltransferase 5 (PRMT5) Over-Expression Is Essential for Epstein-Barr Virus-Driven B-Cell Transformation." In BLOOD. (November 2012). Abstract-.

Stephens,Deborah,Marie; Ruppert,Amy,S; Christian,Beth; Jones,Jeffrey,Alan; Flynn,Joseph,M; Porcu,Pierluigi; Baiocchi,Robert,A; Byrd,John,C; Dotson,Emily,K; Crawford,Brooke,S; Blum,Kristie,A. "Toxicity in patients (pts) age 65 or older with dose-adjusted REPOCH (DA-REPOCH) for untreated diffuse large B-cell lymphoma (DLBCL).." In JOURNAL OF CLINICAL ONCOLOGY. (May 2012). Abstract-.

Hofmeister,Craig,C; Bowers,Mindy,A; Bingman,Anissa; Lozanski,Gerard; Baiocchi,Robert,A; Falk,William; Benson,Don,M; Efebera,Yvonne,A; Humphries,Kristina; Sell,Megan; Greenfield,Carli,N; Lustberg,Mark,E; Vaughn,John,L; Earl,Christian,Tyler; Geyer,Susan; Devine,Steven,M. "Immune Reconstitution and Quality of Life Analyses After Autologous Transplant for Multiple Myeloma." In BLOOD. (November 2012). Abstract-.

Cohen,J,B; Ruppert,A,S; Kaplan,L,D; Baiocchi,R; Porcu,P; Flynn,J; Penza,S; Jones,J,A; Blum,K,A; Devine,S,M; Andritsos,L,A. "COMPLEX KARYOTYPE (CK) IS ASSOCIATED WITH INCREASED CUMULATIVE INCIDENCE OF RELAPSE (CIR) FOLLOWING AUTOLOGOUS STEM CELL TRANSPLANTATION (ASCT) FOR MANTLE CELL LYMPHOMA (MCL) IN FIRST REMISSION." In BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. (February 2012). S205-S206.

Cohen,Jonathon,B; Geyer,Susan; Lozanski,Gerard; Zhao,Weiqiang; Heerema,Nyla,A; Jones,Jeffrey,A; Porcu,Pierluigi; Christian,Beth; Baiocchi,Robert,A; Maddocks,Kami; Flynn,Joseph,M; Devine,Steven,M; Blum,Kristie,A. "Complete Response (CR) to Induction Therapy in Patients (pts) with Myc plus and Double Hit Non-Hodgkin's Lymphoma (NHL) Is Associated with Prolonged Progression-Free Survival (PFS).." In BLOOD. (November 2012). Abstract-.

Hofmeister,Craig,C; Bowers,Mindy,A; Baiocchi,Robert,A; Lozanski,Gerard; Humphries,Kristina; Blum,Kristie,A; Porcu,Pierluigi; Penza,Sam; Greenfield,Carli,N; Sell,Megan; Earl,Christian,Tyler; Zitesman,Joseph; Quinion,Carl; Lustberg,Mark,E; Andritsos,Leslie,A; Devine,Steven,M. "Post Autologous Transplant Vorinostat (SAHA) in High Risk Lymphoma: Phase 1 Study of Vorinostat Maintenance." In BLOOD. (November 2012). Abstract-.

Cohen,Jonathon,B; Ruppert,Amy,S; Heerema,Nyla,A; Jones,Jeffrey,A; Porcu,Pierluigi; Baiocchi,Robert,A; Christian,Beth; Byrd,John,C; Flynn,Joseph,M; Penza,Sam; Andritsos,Leslie,A; Devine,Steven,M; Blum,Kristie,A. "Complex Karyotype (CK) Is Associated with a Shortened Progression-Free Survival (PFS) in Patients (pts) with Newly Diagnosed Mantle Cell Lymphoma (MCL).." In BLOOD. (November 2012). Abstract-.

SALEM,G; Dunavin,N; Wei,L; Elder,P; Penza,S; Blum,K; Porcu,P; Baiocchi,R; Jones,J; Flynn,J; Andritsos,L; Devine,S,M; Christian,B; Efebera,Y. "Busulfan, cyclophosphamide, etoposide is not superior to carmustine, etoposide, cytarabine, mephalan conditioning prior to autologous stem cell transplantation in patients with Hodgkin's lymphoma and is associated with increased toxicity." In BONE MARROW TRANSPLANTATION. (April 2012). S84-S85.

Shilo,K; Wu,X; Sharma,S; Welliver,M; Duan,W; Villalona,M; Fukuoka,J; Li,C; Sif,S; Baiocchi,R; Otterson,G. "Protein Arginine Methyltransferase-5 Overexpression Is Frequently Observed in Non-Small Cell Lung Carcinomas." In MODERN PATHOLOGY. (February 2013). 467A-467A.

Shilo,K; Wu,X; Sharma,S; Welliver,M; Duan,W; Villalona,M; Fukuoka,J; Li,C; Sif,S; Baiocchi,R; Otterson,G. "Protein Arginine Methyltransferase-5 Overexpression Is Frequently Observed in Non-Small Cell Lung Carcinomas." In LABORATORY INVESTIGATION. (February 2013). 467A-467A.

 

Degrees

1989 B.S., State University of New York College at Buffalo

1993 M.S., State University of New York College at Buffalo

1994 Ph.D., State University of New York College at Buffalo

1999 M.D., The Ohio State University

 

Editorial Activities

2005 - 2007 Proceedings of National Academy of Sciences
2007 - present American Journal of Transplantation
2007 American Journal of Hematology
2007 Cancer Research
2007 Blood
2009 - present mAbs
2010 - present Cancer Immunology
2010 - present Immunotherapy
2010 - present Expert Opinion on Pharmacotherapy
2011 - present American Society of Hematology Annual Meeting Abstract Reviewer - Molecular Pharmacology, Drug Resistance
2011 - present Chemotherapy
2011 - present PloS One
2011 - present European Journal of Immunology
2011 - present EMBO Molecular Medicine
2011 - present British Journal of Cancer
 

Honors

1993 Mark Diamond Research Foundation Award.
1994 New York State Tuition Scholarship for Graduate Studies.
1994 Sigma XI Scientific Research Honor.
1996 American Society of Hematology Travel Award.
1996 American Society of Hematology Medical Student Scholar.
1996 NIH Summer Research Internship in Oncology.
1997 American Society of Hematology Travel Award.
1998 Landacre Society 3rd Place Oral Presentation. Ohio State University.
1998 Landacre Society. Ohio State Univeristy.
1998 American Society of Hematology Travel Award. The Ohio State Univeristy.
1998 American Society of Hematology Medical Student Scholar. Ohio State University.
1999 - present Department of Internal Medicine Medical Student Research Award. The Ohio State University.
2002 NIH T32 Research Fellowship. Ohio State University.
2003 NIH Clinical Research Loan Repayment Award.
2004 James V. Warren Award for Outstanding Research in Internal Medicine.
2005 V Foundation Scholar.
2005 NIH Clinical Research Loan Repayment Award.
2007 Faculty Sponsor President's Salute Christian Earl.
2007 Distinguished Undergraduate Research Mentor. The Undergraduate Research Office.
2007 Faculty Sponsor President's Salute Christian Tyler Earl.
2010 - present Excellence in Teaching Award. Department of Internal Medicine.
2010 Faculty Sponsor President's Salute John Ryu.
2011 Excellence in Teaching Award. Department of Internal Medicine.
2011 Innovator of the Year Nomination. The Ohio State University.
2011 Inventor of the Year Nomination. Tech Columbus, Innovation Award Semi-Finalist.
2012 Early Career Innovator of the Year Nomination. The Ohio State University.
 

Journal Articles

Beecher MS,Baiocchi RA, Linett ML, Krajewski CA, Caligiuri MA.. "Expression of the zeta protein subunit in CD3- NK effectors derived from human thymus." Cellular Immunology. Vol. 155, no. 2. (January 1994.): 508-516.

Baiocchi RA, Caligiuri MA.. "Low-dose interleukin 2 prevents the development of Epstein-Barr virus (EBV)-associated lymphoproliferative disease in scid/scid mice reconstituted i.p. with EBV-seropositive human peripheral blood lymphocytes.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 91, (January 1994.): 5577-5581.

Carson WE, Haldar S, Baiocchi RA, Croce CM, Caligiuri MA.. "The c-kit ligand suppresses apoptosis of human natural killer cells in serum-free media through the upregulation of BCL-2." Proceedings of the National Academy of Science. Vol. 16, no. 91. (January 1994.): 7553-7557.

Baiocchi RA, Bernstein ZP, and Caligiuri MA. Sangre. Vol. 40, (January 1995.): 245-252.

Carson WE, Lindemann MJ, Baiocchi RA, Linett M, Tan JC, Chou C-C, Narula S, Caligiuri MA.. "The functional characterization of interleukin-10 receptor expression on human natural killer cells." Blood. Vol. 85, no. 12. (January 1995.): 3577-3585.

Baiocchi RA, Ross ME, Tan JC, Chou C-C, Sullivan L, Haldar S, Monne M, Seiden MV, Narula SK, Sklar J, Croce CM, Caligiuri MA.. "Lymphomagenesis in the SCID-hu mouse involves abundant production of human interleukin-10." Blood. Vol. 85, no. 4. (January 1995.): 1063-1074.

Carson,W,E; Ross,M,E; Baiocchi,R,A; Marien,M,J; Boiani,N; Grabstein,K; Caligiuri,M,A. "Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro." JOURNAL OF CLINICAL INVESTIGATION. Vol. 96, no. 6. (December 1995.): 2578-2582.

Carson WE, Ross ME, Baiocchi RA, Marinen MJ, Boiani N, Grabstein K, Caligiuri MA.. "Endogenous Production of Interleukin 15 by Activated Human Monocytes is Critical for Natural Killer Cell Production of Interferon." Journal of Clinical Investigation. Vol. 96, (January 1995.): 2578-2582.

Baiocchi, RA, Khatri VP, Lindemann MJ, Ross ME, Papoff G, Caprio AJ, Caprio TV, Fenstermaker R, Ruberti G, Bernstein ZP, Caligiuri MA.. "Phenotypic and functional analysis of Fas (CD95) expression in primary central nervous system lymphoma of patients with acquired immunodeficiency syndrome." Blood. Vol. 90, no. 5. (January 1997.): 1737-1746.

Khatri V, Baiocchi RA, Bernstein ZP, Caligiuri MA. Cancer Journal of Scientific American. Vol. 3, (January 1997.): S129-136.

Khatri,V,P; Baiocchi,R,A; Bernstein,Z,P; Caligiuri,M,A. "Immunotherapy with low-dose interleukin-2: rationale for prevention of immune-deficiency-associated cancer.." cancer journal from Scientific American. Vol. 3, (December 1997.): S129-36.

Baiocchi RA, Bernstein KV, Zale P Caligiuri MA.. Oncology Reports. Vol. 4 no. 1 SUPPL, (January 1997.): 241-246.

Khatri VP, Fehniger TA, Baiocchi RA, Yu F, Shah MH, Schiller DS, Gould M, Gazzinelli RT, Bernstein ZP, Caligiuri MA.. "Low dose interleukin-2 therapy promotes a type 1 cytokine profile in vivo in patients with AIDS and AIDS-associated malignancies." Journal of Clinical Investigation. Vol. 101, no. 6. (January 1998.): 1373-1378.

Baiocchi,R,A; Caligiuri,M,A. "Cytokines in the evolution and treatment of AIDS-lymphoma.." Current opinion in oncology. Vol. 11, no. 6. (November 1999.): 516-521.

Baiocchi RA, Khatri VP, Peng R, Herzig GP, Oberkirrcher AO, Ward PW, Caligiuri MA. "Endogenous CD8+ T cell expansion during Epstein-Barr virus-associated post transplant lymphoproliferative disorder.." Journal of Immunology. Vol. 163, (January 1999.): 500-506.

Baiocchi RA and Caligiuri MA. Current Opinion in Oncology. Vol. 11, (January 1999.): 516-521.

Shah MH, Baiocchi R A , Fehniger TA, Khatri VP, Gould M, Poiesz B, Bernstein, ZP, Caligiuri MA.. Cancer Journal from Scientific American. Vol. 6 no. Suppl. 1, (January 2000.): S45-S51.

Baiocchi, RA, Ward JS, Carrodeguas L, Eisenbeis CF, Peng R, Roychowdhury S, Vourganti S, Sekula T, O'Brien M, Moeschberger M, Caligiuri MA.. "GM-CSF and IL-2 induce specific cellular immunity and provide protection against Epstein-Barr virus lymphoproliferative disorder." Journal of Clinical Investigation. Vol. 108, no. 6. (January 2001.): 887-894.

Porcu P, Eisenbeis CF, Pelletier RP, Davies EA,Baiocchi, R A, Roychowdhury S, Vourganti S, Nuovo GJ, Marsh WL, Ferketich AK, Amy, Henry ML, Ferguson, Ronald M, Caligiuri MA.. "Successful treatment of posttransplantation lymphoproliferative disorder (PTLD) following renal allografting is associated with sustained CD8(+) T-cell restoration.." Blood. Vol. 100, no. 7. (January 2002.): 2341-2348.

Porcu P, Baiocchi RA, Magro C. Current Opinion in Oncology. Vol. 15, (January 2003.): 356-362.

Porcu,P; Baiocchi,R,A; MAGRO,C. "Recent developments in the biology and therapy of T-cell and natural killer-cell lymphomas." CURRENT OPINION IN ONCOLOGY. Vol. 15, no. 5. (September 2003.): 353-362.

Roychowdhury S, Peng R, Baiocchi, R A , Bhatt D, Vourganti S, Grecula J, Gupta N, Eisenbeis CF, Nuovo GJ, Yang W, Schmalbrock P, Ferketich A, Moeschberger M, Porcu P, Barth RF, Caligiuri MA.. "Experimental treatment of Epstein-Barr virus-associated primary central nervous system lymphoma.." Cancer research. Vol. 63, no. 5. (January 2003.): 965-971.

Baiocchi, RA, Roychowdhury S, Srinivas V, Chou J, Chen C-S, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen C-S, Caligiuri MA.. "Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.." Journal of the National Cancer Institute. Vol. 96, no. 19. (January 2004.): 1447-1457.

Porcu P, Baiocchi RA, Roychowdhury S, Eisenbeis CF, Caligiuri MA. Haematologica. Vol. 89, (January 2004.): supl 4-.

Eisenbeis CF, Grainger A, Fischer B, Baiocchi, R A, Carrodeguas L, Roychowdhury S, Chen L, Banks AL, Davis T, Young D, Kelbick N, Stephens J, Byrd JC, Grever MR, Caligiuri, Michael MA, Porcu P.. "Combination immunotherapy of B-cell non-Hodgkin's lymphoma with rituximab and interleukin-2: a preclinical and phase I study.." Clinical cancer research. Vol. 10, no. 18 Pt 1. (January 2004.): 6101-6110.

Cioc AM, Allen C, Kalmar JR, Suster S, Baiocchi, RA; Nuovo GJ.. "Oral plasmablastic lymphomas in AIDS patients are associated with human herpesvirus 8.." The American journal of surgical pathology. Vol. 28, no. 1. (January 2004.): 41-46.

Roychowdhury S, Blaser BW, Freud A, Katz K, Bhatt D, Ferketich A, Bergdall V, Kusewitt D, Baiocchi RA, and Caligiuri MA. "IL-15 but not IL-2 rapidly induces lethal xenogenetic graft versus host disease.." Blood. Vol. 106, (January 2005.): 2433-2435.

VanBuskirk,A; Baiocchi,R; Ferketich,A; Gross,T; Porcu,P; Caligiuri,M. "PTLD risk and IFNG polymorphisms - Response." BLOOD. Vol. 106, no. 4. (August 2005.): 1503-1503.

Shannon V, Nuovo GJ, Porcu P, Baiocchi, RA, Crowson AN, Magro CM.. "Epstein-Barr virus- and human herpesvirus 8-associated primary cutaneous plasmablastic lymphoma in the setting of renal transplantation.." Journal of Cutaneous Pathology. Vol. 32, no. 1. (January 2005.): 35-39.

Rawal YB, Nuovo G, Frambach GE, Porcu P, Baiocchi RA, Magri CM. "The absence of CD20 messenger RNA in recurrent cutaneous B-cell following rituximab therapy.." J Cutan Pathol. Vol. 32, (January 2005.): 616-621.

Mone A, Puhalla S, Whitman S, Baiocchi RA, Cruz J, Vukosavljevic T, Byrd JC, Caligiuri MA, and Porcu P.. "Durable hematological complete response and suppression of HTLV-1 viral load following Alemtuzumab in AZT/IFN refractory adult T-cell leukemia." Blood. Vol. 10, no. 106. (January 2005.): 3380-3382.

Dierksheide,J,E; Baiocchi,R,A; Ferketich,A,K; Roychowdhury,S; Pelletier,R,P; Eisenbeis,C,F; Caligiuri,M,A; VanBuskirk,A,M. "IFN-gamma gene polymorphisms associate with development of EBV+ lymphoproliferative disease in hu PBL-SCID mice." BLOOD. Vol. 105, no. 4. (February 2005.): 1558-1565.

Glaser R, Padgett DA, Litsky ML, Baiocchi, RA; Yang EV, Chen M, Yeh P-E, Klimas NG, Marshall GD, Whiteside T, Herberman R, Kiecolt-Glaser J, Williams MV.. "Stress-associated changes in the steady-state expression of latent Epstein-Barr virus: implications for chronic fatigue syndrome and cancer.." Brain, behavior, and Immunity. Vol. 19, no. 2. (January 2005.): 91-103.

Freud,A,G; Becknell,B; Roychowdhury,S; Mao,H,C; Ferketich,A,K; Nuovo,G,J; Hughes,T,L; Marburger,T,B; Sung,J; Baiocchi,R,A; Guimond,M; Caligiuri,M,A. "A human CD34(+) subset resides in lymph nodes and differentiates into CD56(bright) natural killer cells." IMMUNITY. Vol. 22, no. 3. (March 2005.): 295-304.

Wang L, Baiocchi RA, Pal S, Mosialos G, Caligiuri MA, Sif S. "The BRG1 and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the tumor suppresor gene clindromatosis.." Mol Cell Biol. Vol. 25, (January 2005.): 7953-7965.

Freud A, Becknell B, Roychowdhury S, Mao H, Hughes TA, Marburger TB, Baiocchi RA, Guimond M, and Caliguiri MA. "A novel human CD34(+) subset that constitutively expresses the high affinity interleukin-2 receptor traffics to lymph nodes and differentiates into CD56 bright natural killer cells.." Immunity. Vol. 22, (January 2005.): 295-304.

Dierksheida JE, Baiocchi RA, Ferketich AL, Roychowdhury S, Pelletier RP, Caligiuri MA, and VanBuskirk AM.. "Development of EBV-driven lymphoproliferative disease in the hu-PBL-SCID mouse correlates with specific IFN-gamma gene polymorphisms.." Blood. Vol. 105(4), (January 2005.): 1558-1565.

Glaser R, Padgett D, Litsky M, Baiocchi RA, Yang EV, Chen M, Yeh, P-E, Caligiuri MA, and Williams M. "EBV-encoded dUTPase induces immune dysregulation: Implications for the pathophysiology of EBV-associated malignant disease.." Virology. Vol. 346, (January 2006.): 205-218.

Vanbuskirk A, Baiocchi, RA, Ferketich A, Gross T, Porcu P, Caligiuri, MA.. "IFN-gamma gene polymorphisms and risk of post transplant lymphoproliferative disease.." Blood. Vol. 106, (January 2006.): 107-.

Alinari L, Lapalombella R, Andritsos L, Baiocchi RA, Lin TS, Byrd JC. "Alemtuzumab (Campath-1H) in the treatment of chronic lymphocytic leukemia.." Oncogene. Vol. 26(25), (January 2007.): 3644-3653.

Pal S, Baiocchi RA, Byrd JC, Grever MR, Jacob ST, Sif S. "Low levels of miR-92b\96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma.." EMBO. Vol. 15, no. 26. (January 2007.): 3558-3569.

Alinari L, Geskin L, Grady T, Baiocchi RA, Bechtel M, Porcu P. "Subcutaneous alemtuzumab for Sezary Syndrome in the very elderly." Leukemia Research. Vol. 8, no. 32. (January 2008.): 1299-1303.

Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosavljevic T, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, Perrotti D, Caliguiri M, Chan k, Wu L, Marcucci G. "Interference of the proteasome inhibitor bortezomib with Sp1 dependent DNA methyltransferase transcription: A novel hypomethylating mechanism.." Blood. no. 15; 111. (January 2008.): 2364-2373.

Liu,Shujun; Liu,Zhongfa; Xie,Zhiliang; Pang,Jiuxia; Yu,Jianhua; Lehmann,Esther; Huynh,LeNguyen; Vukosavljevic,Tamara; Takeki,Mitsui; Klisovic,Rebecca,B; Baiocchi,Robert,A; Blum,William; Porcu,Pierluigi; Garzon,Ramiro; Byrd,John,C; Perrotti,Danilo; Caligiuri,Michael,A; Chan,Kenneth,K; Wu,Lai-Chu; Marcucci,Guido. "Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappa B-dependent DNA methyltransferase activity in acute myeloid leukemia." BLOOD. Vol. 111, no. 4. (February 2008.): 2364-2373.

Martin LK, Porcu P, Baiocchi RA, Erter JW, Chaudhury AR. "Primary central nervous system lymphomatoid granulomatosis in a patient receiving azathioprine therapy.." Clin Adv Hematol Oncol. Vol. 1, no. 7. (January 2009.): 65-68.

Blum,Kristie,A; Hamadani,Mehdi; Phillips,Gary,S; Lozanski,Gerard; Johnson,Amy,J; Lucas,David,M; Smith,Lisa,L; Baiocchi,Robert; Lin,Thomas,S; Porcu,Pierluigi; Devine,Steven,M; Byrd,John,C. "Prolonged myelosuppression with clofarabine in the treatment of patients with relapsed or refractory, aggressive non-Hodgkin lymphoma." LEUKEMIA & LYMPHOMA. Vol. 50, no. 7. (January 2009.): 1232-1234.

Blum KA; Hamadani M; Phillips GS; Lozanski G; Johnson AJ; Lucas DM; Smith LL; Baiocchi RA; Lin TS; Porcu P; Devine SM; Byrd JC. "Prolonged myelosuppression with clofarabine in the treatment of patients with relapsed or refractory, aggressive non-Hodgkin lymphoma.." Leukemia & Lymphoma. Vol. 50, no. 3. (March 2009.): 349-356.

Alinari L, White V, Earl T, Lin T, Ryan T, Johnston J, Dalton J, Lai R, Ferketich A, Porcu P, Blum K, Byrd J, Muthusamy N,  Baiocchi RA.. "Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in Mantle Cell Lymphoma." mAbs. Vol. 1, no. 1. (January 2009.): 31-40.

Blum KA; Liu Z; Lucas DM; Chen P; Xie Z; Baiocchi RA; Benson DM; Devine SM; Jones J; Andritsos L; Flynn J; Plass C; Marcucci G; Chan KK; Grever MR; Byrd JC. "Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation.." British Journal Of Haematology. Vol. 150, no. 2. (July 2010.): 189-195.

Yan F; Wu X; Crawford M; Duan W; Wilding EE; Gao L; Nana-Sinkam SP; Villalona-Calero MA; Baiocchi RA; Otterson GA. "The search for an optimal DNA, RNA, and protein detection by in situ hybridization, immunohistochemistry, and solution-based methods.." Methods (San Diego, Calif.). Vol. 52, no. 4. (December 2010.): 281-286.

Prescott HC; Wu HM; Cataland SR; Baiocchi RA. "Eculizumab therapy in an adult with plasma exchange-refractory atypical hemolytic uremic syndrome.." American Journal Of Hematology. Vol. 85, no. 12. (December 2010.): 976-977.

Benson DM Jr; Bakan CE; Mishra A; Hofmeister CC; Efebera Y; Becknell B; Baiocchi RA; Zhang J; Yu J; Smith MK; Greenfield CN; Porcu P; Devine SM; Rotem-Yehudar R; Lozanski G; Byrd JC; Caligiuri MA. "The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.." Blood. Vol. 116, no. 13. (September 2010.): 2286-2294.

Majumder S; Alinari L; Roy S; Miller T; Datta J; Sif S; Baiocchi RA; Jacob ST. "Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription.." Journal Of Cellular Biochemistry. Vol. 109, no. 3. (February 2010.): 553-563.

Liu S; Wu LC; Pang J; Santhanam R; Schwind S; Wu YZ; Hickey CJ; Yu J; Becker H; Maharry K; Radmacher MD; Li C; Whitman SP; Mishra A; Stauffer N; Eiring AM; Briesewitz R;Baiocchi RA; Chan KK; Paschka P; Caligiuri MA; Byrd JC; Croce CM; Bloomfield CD; Perrotti D; Garzon R; Marcucci G. "Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.." Cancer Cell. Vol. 17, no. 4. (April 2010.): 333-347.

Lin TS; Blum KA; Fischer DB; Mitchell SM; Ruppert AS; Porcu P; Kraut EH; Baiocchi RA; Moran ME; Johnson AJ; Schaaf LJ; Grever MR; Byrd JC. "Flavopiridol, fludarabine, and rituximab in mantle cell lymphoma and indolent B-cell lymphoproliferative disorders.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 28, no. 3. (January 2010.): 418-423.

Lucas DM; Alinari L; West DA; Davis ME; Edwards RB; Johnson AJ; Blum KA; Hofmeister CC; Freitas MA; Parthun MR; Wang D; Lehman A; Zhang X; Jarjoura D; Kulp SK; Croce CM; Grever MR; Chen CS; Baiocchi RA; Byrd JC. "The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo.." Plos One. Vol. 5, no. 6. (June 2010.): e10941-.

Liu Q; Alinari L; Chen CS; Yan F; Dalton JT; Lapalombella R; Zhang X; Mani R; Lin T; Byrd JC; Baiocchi RA; Muthusamy N. "FTY720 shows promising in vitro and in vivo preclinical activity by downmodulating Cyclin D1 and phospho-Akt in mantle cell lymphoma.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 16, no. 12. (June 2010.): 3182-3192.

Baiocchi RA, Alinari L, Lustberg ME, Lin TS, Porcu P, Jones J, Flynn J, Hicks W, Lucas MS, Li X, Johnston JS, Byrd JC, Blum KA. "Phase II trial of rituximab and bortezomib in patients with relapsed or refractory mantle cell and follicular lymphoma: Significant activity in patients with follicular lymphoma." Cancer. (December 2010.): -.

Ramaswamy B, Phelps MA, Baiocchi RA, Bekkaii-Saab T, Ni W, Lai JP, Wolfson A, Lustberg ME, Wei L, Wilkins D, Campbell A, Arbogast D, Doyle A, Byrd JC, Grever MR, Shah MH.. "A dose-finding, pharmacokinetic and pharmacodynamic study of a novel schedule of flavopiridol in patients with advanced solid tumors.." Invest New Drugs. Vol. 30, no. 2. (October 2010.): 629-38.

Alinari L; Mahoney E; Patton J; Zhang X; Huynh L; Earl CT; Mani R; Mao Y; Yu B; Quinion C; Towns WH; Chen CS; Goldenberg DM; Blum KA; Byrd JC; Muthusamy N; Prætorius-Ibba M; Baiocchi RA. "FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death.." Blood. Vol. 118, no. 26. (December 2011.): 6893-.

Baiocchi,Robert,A; Alinari,Lapo; Lustberg,Mark,E; Lin,Thomas,S; Porcu,Pierluigi; Li,Xiaobai; Johnston,Jeffrey,S; Byrd,John,C; Blum,Kristie,A. "Phase 2 Trial of Rituximab and Bortezomib in Patients With Relapsed or Refractory Mantle Cell and Follicular Lymphoma." CANCER. Vol. 117, no. 11. (June 2011.): 2442-2451.

Karkhanis V; Hu YJ; Baiocchi RA; Imbalzano AN; Sif S. "Versatility of PRMT5-induced methylation in growth control and development.." Trends In Biochemical Sciences. Vol. 36, no. 12. (December 2011.): 633-.

Alinari L; Yu B; Christian BA; Yan F; Shin J; Lapalombella R; Hertlein E; Lustberg ME; Quinion C; Zhang X; Lozanski G; Muthusamy N; Prætorius-Ibba M; O'Connor OA; Goldenberg DM; Byrd JC; Blum KA; Baiocchi RA. "Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma.." Blood. Vol. 117, no. 17. (April 2011.): 4530-.

Alinari L, Baiocchi RA, Prætorius-Ibba M. "FTY720-induced blockage of autophagy enhances anti-cancer efficacy of milatuzumab in mantle cell lymphoma; is FTY720 the next autophagy-blocking agent in lymphoma treatment?." Autophagy. (December 2011.): -.

Alinari,Lapo; Prince,Courtney,J; Edwards,Ryan,B; Towns,William,H; Mani,Rajeswaran; Lehman,Amy; Zhang,Xiaoli; Jarjoura,David; Pan,Li; Kinghorn,A,Douglas; Grever,Michael,R; Baiocchi,Robert,A; Lucas,David,M. "Dual Targeting of the Cyclin/Rb/E2F and Mitochondrial Pathways in Mantle Cell Lymphoma with the Translation Inhibitor Silvestrol." CLINICAL CANCER RESEARCH. Vol. 18, no. 17. (September 2012.): 4600-4611.

Tiwari R; Toppino A; Agarwal HK; Huo T; Byun Y; Gallucci J; Hasabelnaby S; Khalil A; Goudah A; Baiocchi RA; Darby MV; Barth RF; Tjarks W. "Synthesis, Biological Evaluation, and Radioiodination of Halogenated closo-Carboranylthymidine Analogues (1).." Inorganic Chemistry. Vol. 51, no. 1. (January 2012.): 629-.

Alinari,Lapo; Christian,Beth; Baiocchi,Robert,A. "Novel targeted therapies for mantle cell lymphoma." ONCOTARGET. Vol. 3, no. 2. (February 2012.): 203-211.

Alinari,Lapo; Pant,Shubham; McNamara,Kristin; Kalmar,John,R; Marsh,William; Allen,Carl,M; Baiocchi,Robert,A. "Lymphomatoid granulomatosis presenting with gingival involvement in an immune competent elderly male.." Head and neck pathology. Vol. 6, no. 4. (December 2012.): 496-501.

Klionsky,Daniel,J; Abdalla,Fabio,C; Abeliovich,Hagai; Abraham,Robert,T; Acevedo-Arozena,Abraham; Adeli,Khosrow; Agholme,Lotta; Agnello,Maria; Agostinis,Patrizia; Aguirre-Ghiso,Julio,A; Ahn,Hyung,Jun; Ait-Mohamed,Ouardia; Ait-Si-Ali,Slimane; Akematsu,Takahiko; Akira,Shizuo; Al-Younes,Hesham,M; Al-Zeer,Munir,A; Albert,Matthew,L; Albin,Roger,L; Alegre-Abarrategui,Javier; Aleo,Maria,Francesca; Alirezaei,Mehrdad; Almasan,Alexandru; Almonte-Becerril,Maylin; Amano,Atsuo; Amaravadi,Ravi; Amarnath,Shoba; Amer,Amal,O; Andrieu-Abadie,Nathalie; Anantharam,Vellareddy; Ann,David,K; Anoopkumar-Dukie,Shailendra; Aoki,Hiroshi; Apostolova,Nadezda; Arancia,Giuseppe; Aris,John,P; Asanuma,Katsuhiko; Asare,Nana,YO; Ashida,Hisashi; Askanas,Valerie; Askew,David,S; Auberger,Patrick; Baba,Misuzu; Backues,Steven,K; Baehrecke,Eric,H; Bahr,Ben,A; Bai,Xue-yuan; Bailly,Yannick; Baiocchi,Robert; et al. "Guidelines for the use and interpretation of assays for monitoring autophagy." AUTOPHAGY. Vol. 8, no. 4. (April 2012.): 445-544.

Alinari L, Christian B, Baiocchi RA.. "Novel targeted therapies for mantle cell lymphoma." Oncotarget. (January 2012.): -.

 

Reference Works

January 1991 Villalona-Calcero M, Stewart C, Baiocchi RA, Caligiuri MA, Foon KA."Phenotypic characteristics of "prolymphocytoid" transformmed (CLL/PLL) chronic lymphocytic leukemia (CLL) cells." . : 230
January 1993 Bernstein ZP, Baiocchi RA, Bankert RB, Herzig G, and Caligiuri MA."Low dose IL-2 therapy in HIV associated lymphoma." .
January 1993 Baiocchi RA, and Caligiuri MA."Low dose IL-2 prevents the development of Epstein Barr virus associated lymphoproliferative disorder in the hu PBL SCID mouse model" . : 385A
January 1994 Carson WE, Haldar S, Baiocchi RA, and Caligiuri MA."The c-kit ligand suppresses apoptosis of human natural killer cells in serum-free media through the upregulation of BCL 2" . : 3
January 1994 Baiocchi RA, Sullivan L, Tan J, Narula S, and Caliguiri MA."Epstein-barr virus-associted lymphoproliferative disease (EBV-LPD) in the severe combined immune deficient human/mouse model: Prevention with low-dose interleukin-2 supresses production of human interleukin-6 and interleukin-10." . : 287
January 1994 Baiocchi RA, Haldar S, Sullivan L, Tan JC, Seiden MV, Narula SK, and Caligiuri MA."Human IL-10 and BCL-2 are abberantly expressed in severe combined immune deficient mouse/human chimeras with Epstein Barr virus lymphoproliferative disease" .
January 1994 Baiocchi RA, Caliguiri MA."Preventative strategies for EBV-Lymphomagenesis in the hu-PBL-SCID mouse model." Buffalo, NY.
January 1995 Carson WE, Ross ME, Baiocchi RA, Marian M, Boiani N, Grabstein K, and Caligiuri MA."Endogenous production of interleukin-15 by activated monocytes is critical for optimal production of interferon by human natural killer cells in vitro" Natural Immunity. : 79
January 1996 Baiocchi RA, Khatri V, Lindemann MJ, Ross ME, Caprio A, Caprio T, Fenstermaker R, Bernstein ZP, and Caligiuri MA."Analysis of FAS/CD95 expression and function in Epstein-barr virus associated human B cell tumors." Blood. : Suppl 1:504a
January 1996 Baiocchi RA and Caligiuri MA."Cytokine regulation of Epstein-Barr associated lymphoma in the hu-PBL-SCID mouse." State Univeristy of New York at Buffalo School of Medicine and Biomedical Sciences.
January 1997 Khatri V,Baiocchi RA, and Caligiuri MA."A successful endogenous human immune response to transplantation-associated Epstein-barr virus (EBV) monoclonal B-cell lymphoma." . : 45
January 1997 Khatri V, Yu F, Baiocchi RA, Shah M, Zwerling BH, Gould M, Bernstein ZP, and Caligiuri MA."Analysis of Th1/Th2 cytokine gene profile during low dose IL-2 therapy in patients with AIDS or AIDS lymphoma." Journal of Acquired Immune Deficiency and Human Virology. : 122
January 1997 Khatri V, Yu F, Baiocchi RA, Shah M, Zwerling BH, Gould M, Bernstein ZP, and Caligiuri MA."Low dose IL-1 enhances the innate immunity and restores the protective Th1 cytokine profile in patients with AIDS/AIDS lymphoma." Natural Immunity. : 99
January 1997 Khatri V, Baiocchi RA, and Caligiuri MA."A successful endogenous human immune response to transplantation-associated Epstein-barr virus (EBV) monoclonal B-cell lymphoma." . : 9
January 1997 Baiocchi RA,, Khatri V, Lindemann MJ, Ross ME, Caprio AJ, Caprio TV, Fenstermaker RA, Bernstein ZP and Caligiuri MA."Phenotypic and functional analysis of FAS/CD95 expression primary central nervous system lymphoma of patients with the aquired immune deficiency syndrome." State University of New York at Buffalo School of Medicine and Biomedical Sciences.
January 1997 Baiocchi RA, Lindemann MJ, Nordone P, and Caligiuri MA."Combination cytokine therapy prevents human EBV-associated lymphoproliferative disease in the human-PBL-SCID mouse model: critical role of human natural killer cells." Blood. : Suppl 1:512a
January 1999 Baiocchi RA, Peng R, Schmalbrock P, Moeschberger M, Barth R, and Caligiuri MA."An in vivo model to evaluate an effective antiviral regimen in Epstein-barr virus (EBV)-associated primary central nervous system lymphoma." .
January 1999 Baiocchi RA, Peng R, Schalmbrock P, Moeschberger M, Barth R and Caligiuri MA."Combination antiviral therapy for treatment of primary central nervous system lymphoma associated with the Epstein-barr virus: In vivo evaluation in an animal model." .
January 1999 Baiocchi RA, Carson WE, Carrodeguas L, Dierksheide JE, Marsh C, Roychowdhury S, Peng R, and Caligiuri MA."Combination humanized-monoclonal antibody and cytokine therapy for treatment of human malignancy." J Immunotherapy.
January 1999 Baiocchi RA, Carredeguas L, Peng R, and Caliguiri MA."Combination Rituximab/Interleukin-2 therapy prevents human Epstein-barr virus-associated lymphoproliferative disease (EBV-LPD) in the hu-PBL-SCID mouse depleted of murine NK cells." .
January 1999 Schmalbrock P, Chakeres D, Peng R, Caligiuri MA, Baiocchi RA, Stredney D, Sessanna D, and Kwok WC."Comparison of MRI and Histology of a Rat Brain Lymphoma Tumor Model using Volume Graphics" Heidelberg Germany.
January 1999 Carrodeguas L, Baiocchi RA, Roychowdhury S, Peng R, and Caligiuri MA."Combination Rituximab/Interleukin-2 therapy effectively treats established human Epstein-Barr virus-associated lymphoproliferative disease (EBV-LPD) in the hu-PBL-SCID mouse depleted of murine NK cells" . : 90A
January 2001 Baiocchi RA, Sekula T, Courganti S, Nair V, Roychowdhury S, Pathun M, Nuovo G, Marcucci G, Byrd J, Grever M and Caliguiri M."Treatment of EBV-transformed B cell lines with depsipeptide results in the induction of a viral thymidine kinase and enhanced susceptibility to antiviral-induced apoptosis." Clinical Cancer Research.
January 2001 Porcu P, Pelletier RP, Davies EA, Baiocchi RA, Eisenbies CF, Roychowdhury S, Nuovo GJ, Marsh W, Vanbuskirk A, Henry ML, Ferguson RM, and Caliguiri MA."Post-transplant lymphoproliferative disorders following renal allografting: prospective immunological and molecular monitoring identifies correlates of clinical response to reduction of immune suppression and antiviral therapy." .
January 2002 Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Chou JD, Eisenbeis CF, Grever MR, and Caligiuri MA."The histine deacetylase inhibitor depsipeptide (FR901228) selctively induces apoptosis in latency type III Epstein-barr virus (EBV) transformed lymphoblastoid cells (lCL) and is enhanced by the inhibition of NFB." . : 780a
January 2002 Baiocchi RA, Peng R, Roychowdhury S, Vourganti S, Bhatt D, Sekula T, Grecula J, Eisenbies C, Procu P, and Caligiuri MA."Combination Antiviral therapy to treat Epstein-barr virus-associated promary central nervous system lymphoma." . : 7a
January 2004 Porcu P, Baiocchi RA, Buckner M, Byrd JC, Magro CM."Bexarotene-induced t-cell immunomodulation and response in CTCL." Blood. : 744
January 2004 Freud AG, Becknell B, Roychowdhury S, Mao HC, Ferketich AK, Nuovo GJ, Hughes TL, Marburger TB, Sung J, Baiocchi RA, Guimond M and Caliguiri MA."A novel human CD34(+) subset that constitutively expresses the high affinity interleukin-2 receptor traffics to lymph nodes and differentiates into CD56 bright natural killer cells." Blood. : 314
January 2005 Wadehra N, Lin T, Ryan T, Schneider A, Pepple A, Johnston J, Dalton J, Banks A, Eisenbeis CF, Lai R, Byrd JC, Blum K, Baiocchi RA.."Combination bortezomib (PS341, Velcade) and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma" Blood.
January 2005 Grady T, Nelson M, Staub A, Tucker M,Baiocchi RA, Nuovo G, Magro C, and Porcu P."Elevated peripheral blood (PB) cytomegalovirus (CMV) viral loads and reduced CD8* t-cell counts are common findings in T-cell lymphomas before systemic therapy." Blood.
January 2005 Mone A, Puhalla S, Whitman S, Baiocchi RA, Cruz J, Vukosavljevic T, Banks A, Eisenbies C, Byrd JC, Caliguiri MA and Porcu P."Durable hematological complete response and suppression of HTLV-1 viral load following Alemtuzumab in AZT/IFN refatory adult T-cell leukemia." Blood.
January 2006 Blum KA, Lucas MS, Johnston JS, Daloton J, Young D, Baiocchi RA, Lin TS, Procu P, Byrd JC."Excessive Neurotoxicity in a phase II trial of combined bortezomib and rituximab in patients with relapsed/refactory mantle cell (MCL) and follicular (FL) non-Hodgkin's lymphoma." Blood. : 2768
November 2006 Liu S, Pang J, Yu J, Liu Z, Huynh L, Kearney J, Paschka P, Klisovic R, Baiocchi RA, Blum W, Perotti D, Marcucci G.."Bortezomib-induced down-regulation of KIT is medicated by inhibition of Sp1 and NF-kB in AML1/ETO-positive cells." .
January 2007 Lapalombella R, Roda JM, Baiocchi RA, Zhukocksy E, Desjarlais J, Muthusamy N, Byrd, JC."Preclinical activity of a novel fcgRIIIa engineered CD19 monoclonal antibody in B cell CLL and ALL" . : 695a
January 2007 Porcu P, Baiocchi RA, Liu T, Caligiuri MA.""A vaccine-based strategy to enhance Epstein Barr Virus (EBV)-specific T-cell responses to prevent post-transplant lymphoproliferative disorder (PTLD)."" Chicago.
January 2007 Porcu P, Baiocchi RA, Lin TS, Blum KA, Curtis P, Grever MR, Byrd JC."A phase 1 trial of subcutaneous dose-escalated alemtuzumab in patients with t cell lymphoproliferative disorders" . : 1001A
January 2007 Baiocchi RA, Kim D, Yeh E."Histone deacetylase inhibition modulates tumor-specific innate cellular immunity." .
January 2007 Baiocchi RA and Murthy S."Management of aggresive lymphomatoid granulomatosis" .
January 2007 Baiocchi RA and Lin K."Syncope as presenting feature in progressive HIV-associated Burkitt's Lymphoma" .
January 2008 Blum K, Baiocchi RA, Alinari L, Lin T, Porcu P, Jones J, Flynn J, Hicks W, Lucas M, Wei L, Johnston J, Byrd J.."Phase II Trial of induction plus maintenance rituximab and bortezomib in patients with relapsed/refactory mantle cell (MCL) and follicular (FL) non-hodgkin's lymphoma." .
January 2008 Lin T, Fischer B, Blum K, Porcu P, Kraut E, Baiocchi RA, Moran M, Mitchell M, Grever M, Byrd J.."An active regimen in indolent B-cell lymphoproliferative disorders and mantle cell lymphoma." .
January 2008 Alinari L, Hartlein E, Goldenberg D, Lapalombella R, Yan F, Zhang X, Lucas D, Nuthusamy N, Byrd J, Baiocchi RA.."Combination anti-CD74 (Milatuzumab) and CD20 (Rituximab) Monoclonal Antibody therapy has in vitro and in vivo activity in Mantle Cell Lymphoma." .
January 2009 Alinari L, Christian B, Yu B, Shin J, Hertlein E, Lapalombella R, Yan F, Lesinski GB, Zhang X, Lozanski G, Muthusamy N, Goldenberg DM, Byrd JC, Baiocchi RA.."Co-Treatment with Milatuzumab (Anti-CD74 mAb) and Rituximab (Anti-CD20 mAb) Results in the Induction of Mantle Cell Lymphoma Cell Death that is Dependent on Actin Polymerization and Inhibition of NF-kB" New Orleans.
December 2009 Liu S, Lai C-W, Pang J, Ramasamy S, Schwind S, Wu Y-Z, Hickey C, Yu J, Mishra A, Becker H, Li C, Briesewitz R, Baiocchi RA, Chan KK, Caligiuri MA, Byrd JC, Perrotti D, Garzon R, Marcucci G.."Evidence of MicroRNA-29b and Sp1/NFB-HDAC Regulatory Network for KIT Expression in KIT-Driven Acute Myeloid Leukemia (AML): Biologic and Therapeutic Implications." New Orleans. : 938
April 2009 Liu T, Wen J, House M, Clark R, Baiocchi RA, Caliguiri MA.."Defining a novel vaccine strategy for Epstien-barr virus-associated post-transplant lymphoproliferative disorder." .
April 2009 Benson D, Chandler J, Mishra A, Baiocchi RA, Yu J, Liu T, Lozenski G, Porcu P, Devine S, Rotem-Yehudar R, Caliguiri M.."CT-011, a monoclonal PD-1 blocking antibody, enhances natural killer cell activation and cytotoxicity against multiple myeloma." .
December 2009 Awan F, Lapalombella R, Trotta R, Butchar JP, Yu B, Benson D, Cheney C, Mo X, Lehman A, Jones JA, Flynn JM, Jarjoura D, Baiocchi RA, Desjarlais J, Tridandapani S, Caligiuri MA, Muthusamy N, Byrd JC.."CD19 Targeting of Lymphoid Malignancies by Novel Fc-Domain Engineered Monoclonal Antibody" New Orleans. : 3725
December 2009 Alinari L, Liu Q, Chen C-S, Yan F, Dalton JT, Lapalombella R, Zhang X, Lin T, Byrd JC, Baiocchi RA Muthusamy N.."FTY720 Demonstrates Promising in-Vitro and in-Vivo Pre-Clinical Activity by Down-Modulation of Cyclin D1 and Pakt in Mantle Cell Lymphoma." New Orleans. : 3725
December 2010 Christian B, Alinari L, Earl CT, Wilding E, Quinion C, Lustberg M, Benson DM, Jones JA, Byrd JC, Wegener WA, Goldenberg DM, Baiocchi RA, Blum KA."A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin’s Lymphoma" Orlando. : 2788
December 2010 Baiocchi RA, Flynn JM, Jones JA, Blum KA, Hofmeister CC, Poon J, Small K, Statkevich P, Grever MR, Bannerji R, and Byrd JC."Early Evidence of Anti-Lymphoma Activity of the Cyclin Dependent Kinase Inhibitor Dinaciclib (SCH 727965) In Heavily Pre-Treated Low Grade Lymphoma and Diffuse Large Cell Lymphoma Patients" Orlando. : 3966
December 2010 Jones JA, Andritsos LA, Baiocchi RA, Benson DM., Blum KA, Christian B, DeamD, Flynn JM, Johnson AJ, Phelps MA, Porcu P, Byrd JC and Grever, MR."Flavopiridol Can Be Safely Administered Using a Pharmacologically Derived Schedule and Demonstrates Activity In Relapsed and Refractory Non-Hodgkin’s Lymphoma" Orlando. : 2834
April 2010 Yan F, Alinari L, Lustberg M, Martin LK, Nowicki O, Wu X, Yu B, Gordon K, Wolfson A, Ryu J, Kaur B, Kwon C-H, Lawler S, Nuovo G, Liu S, Marcucci G, Byrd JC, Chiocca EA, Baiocchi RA.."Targeting protein arginine methyltransferase 5 (PRMT5) enzyme over expression in high grade astrocytomas" . : Abstract #1584
October 2010 Cole C, Baiocchi RAChristian B, Gardner M, Smith A, Heerema NA."A Complex Karyotype with a Four=-Way Translocation 47,XX,t(3;12;19;14) (q27;q13;q13.3;q32), del (6) q13),+mar in a patient with Diffuse Large B-Cell Lymphoma" . : 158
July 2011 Lucas DM, Alinari L, Patton JT, Kinghorn AD, Baiocchi RA, Grever MR.."The Protein Synthesis Inhibitor Silvestrol Has In Vitro and In Vivo Efficacy in Aggressive B-cell Malignancies" Washington.
December 2011 Yan F, Smith P, Alinari L, Karkhanis V, Tae S, Patton JT, Wilding EE, Gordon K, Manhasenan K, Bhasin D, Agostinelli C, Pileri S, Byrd JC, Sif S, Li P-K, Li C, Baiocchi RA."Developing a novel class of drug to inhibit protein arginine methyltransferase 5 (PRMT5) enzyme dysregulation in mantle cell lymphoma." San Diego.
April 2011 Nicholas C, Yan F, Peters S, Bill MA, Li P-K, Li C, Fuchs JR, Baiocchi RA, Lesinski GB.."The expression of PRMT5 methyltransferase mediates cell survival and metastatic phenotype in malignant melanoma." Orlando.
December 2011 Patton JT, Lustberg ME, Garman SL, Kinghorn AD, Pan L, Lucas DM, Grever MR, Baiocchi RA."Silvestrol Modulates Direct Anti-tumor Activity Against Epstein-Barr Virus (EBV)-Associated Lymphomas while Sparing Innate and Antigen Specific Adaptive Immunity" San Deigo.
December 2011 Martin K, Lustberg ME, Yan F, Patton JT, Porcu P, Nuovo G, Cavaliere R, Baiocchi RA."Successful treatment of Primary Central Nervous System Post-Transplant Lymphoproliferative Disorder (PCNS-PTLD) with Zidovudine (AZT), Ganciclovir (GCV), Rituximab and Dexamethasone: a Single-Institution Case Series" San Deigo.
December 2011 Lustberg ME, Pelletier R, Porcu O, Martin S,Baiocchi RA."Risk factors for Post-transplant lymphoproliferative disorder in solid organ transplant recipients" San Diego.
December 2011 Cohen JB, Hall N, Ruppert AS, Jones JA, Porcu P, Baiocchi RA, Penza S, Benson DM, Jr, Andritsos LA, Flynn JM, Devine SM, Blum KA.."The Prognostic Value of FDG PET/CT Prior to Autologous Stem Cell Transplant in Mantle Cell Lymphoma" San Diego.
December 2011 Christian B, Alinari L, Jones JA, Benson DM Jr, Flynn JM, Porcu P, Lustberg ME, Phelps M, Poi M, Chung D, Quinion C, Byrd JC, Wegener W, Goldenberg DM, Baiocchi RA, Blum KA.."Results of A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma" San Diego.
December 2011 Alinari L, Mahoney E, Patton JT, Zhang X, Huynh L, Earl CT, Mani R, Mao Y, Yu B, Towns WH, Chen C-S, Goldenberg DM, Blum KA, Byrd JC, Muthusamy N, Prætorius-Ibba M, Baiocchi RA."FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death" San Deigo.
December 2011 Alinari L, Edwards R, Prince C, Towns W, Mani R, Lehman A, Zhang X , Jarjoura D, Pan L, Kinghorn AD, Grever MR, Baiocchi RA, Lucas DM."Targeting the Cyclin D - CDK4/6 - Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol" San Deigo.

Softwares

January 2011 Baiocchi RA."AIDS/HIV Cancer Website"

Inventions and Patents

Baiocchi, RA, Caligiuri MA. "A method for inducing apoptosis of primary central nervous system B cell lymphomas." Filed January 1998.

Baiocchi, RA, Caligiuri MA, Vanbuskirk A. "Methods to treat or prevent viral-associated lymphoproliferative disorders with TGF-B antagonists." Filed January 2005.

Baiocchi, RA, Caliguiri MA.. "Methods and compositions for preventing Epstein-Barr associated disease." Filed January 2006.

Baiocchi RA, Chenglong Li, Fengting Yan. "Identification and Use of Compounds to Inhibit PRMT5 Enzyme Activity for Cancer Therapeutics." OSU. Filed January 2010.

Baiocch, RA. "Compositions and Methods for Regulating Immune Function." Arno Pharmaceuticals. Filed January 2010.

Alinari, LBaiocchi RA. "FTY720 Increases CD74 Expression and Sensitizes Mantle Cell Lymphoma Cells to Milatuzumab-Mediated Cell Death." Immunomedics. Filed January 2011.

Baiocchi RA, Patton J, Lucas DM, Grever MR, Kinghorn AD. "Immune Modulatory Properties of Silvestrol." Filed January 2011.

 

Presentations

"Detection and treatment of EBV lymphoma in the SCID-hu mouse.." Presented at University of Guelph, . (June 1993)

"EBV-Associated lymphoproliferative disease in the hu-PBL-SCID mouse: Cykotine imbalances and implications for tumor growth.." Presented at Roswell Park Institute, Department of Molecular Immunology, . (November 1993)

"Epstein-Barr virus-associated lymphoproliferative disease in the severe combined immune deficient human/mouse model: Prevention with low dose interleukin--2 supresses production of human interleukin-6 and interleukin-10.." Presented at The American Society of Clinical Oncology, . (May 1994)

"The role of interleukin-15 in innate immunity.." Presented at State University of New York at Buffalo School of Medicine and Biomedical Sciences, . (November 1996)

"FAS expression in primary central nervous system lymphoma of patients with the acquired immune deficiency syndrome.." Presented at 48th Annual Landacre Day Research Forum, Ohio State University, Columbus, OH. (April 1998)

"Management of Hodgkin's Disease." Presented at Noon Conference at Mount Carmel West Medical Center, Columbus, OH. (March 1999)

"Current approaches to post-transplant Lymphoproliferative Disease." Presented at Department of Surgery, Ohio State University, Columbus, OH. (January 1999)

"Combination Antiviral Therapy for treatment of primary central nervous system lymphoma associated with the Epstein-Barr Virus: In Vivo Evaluation in an animal model.." Presented at Third National AIDS Malignancy Conference, National Institutes of Health, Bethesda, MD. (May 1999)

"Induction of the EBV thymidine kinase gene product to target antiviral therapy at EVB-associated malignancies.." Presented at Department of Microbiology and Immunology, Columbus, OH. (February 2001)

"Combination Antiviral Therapy to treat Epstein-Barr Virus-Associated Primary Central Nervous System Lymphoma." Presented at American Society of Clinical Oncology, Orlando, FL. (May 2002)

"Post Transplant Lymphoproliferative Disease in Renal Transplantation." Presented at Internal Medicine Noon Conference, Columbus, OH. (July 2002)

"Advances in management of post transplant lymphoproliferative diseases.." Presented at Cancer Center Grand Rounds, Rochester, NY. (March 2004)

"Targeting lytic and latent gene products in EBV-associated malignancies.." Columbus, OH. (October 2004)

"Treatment of Epstien-Barr Virus-associated lymphoproliferative disorders with histone deacetylase inhibitors.." Presented at Regional Cancer Consortium for the Biological Therapy of Cancer, Buffalo, NY. (February 2004)

"Targeting lytic gene products in EBV-positive lymphomas.." Presented at University of Michigan Cancer Center, Ann Arbor, MI. (February 2004)

"Developing strategies to target Epstien-Barr virus positive lymphomas.." Presented at Cancer Center Grand Rounds, Bloomington, IN. (January 2004)

"Infection, Inflammation and Lymphoma." Chillicothe, OH. (February 2005)

"Modulation and Targeting of Viral Protiens in Epstein-Barr Virus-Associated Malignancies." . (April 2006)

"Utilizing Research tools to care for patients with Cancer. Technology Enhanced Learning and Research." Presented at Research on Research Program, OSU Digital Union, Columbus, OH. (August 2006)

"Vaccine approaches to treat Epstein-Barr Virus-Associated disease.." Columbus, OH. (February 2006)

"Combination Bortezomib and Rituximab to treat Mantle Cell Lymphoma." Presented at 9th Annual Meeting of the Regional Cancer Center Consortium for the Biological Therapy of Cancer, Pittsburgh, PA. (February 2006)

"Overview of Baiocchi Laboratory Program for Viral Oncogenesis Program Annual Retreat." . (March 2006)

"AIDS Malignancies." Presented at Basic Science and Clinical Lecture Series, Columbus, OH. (March 2006)

"How to apply, interview, and negotiate contracts for a laboratory based academic Hematology Oncology position.." Presented at Fellow's Job Search Seminar, . (September 2007)

"The Role of Translational Research in Patient Care." Columbus, OH. (April 2007)

"Translating basic science from the laboratory to the clinic." Presented at Cutting Edge Lecture. Host Defense Series, Columbus, OH. (March 2008)

"Targeting the Protein Arginine Methyltransferase Enzyme in Mantle Cell Lymphoma." Presented at Mantle Cell Lymphoma Scientific Workshop, Dallas, TX. (March 2008)

"Pharmacodynamics and pharmacology of chemotherapy regimins to treat HIV-associated lymphomas.." Presented at Department of Pharmacy, Columbus, OH. (March 2008)

"Developing Vaccine Strategies to Prevent EBV-Associated Lymphomas-Therapy Accelarated Program." Presented at Leukemia Lymphoma Society. Translational Research Program, Kansas City, MO. (March 2008)

"AIDS malignancies." Presented at Basic Science and Clinical Lecture Series, . (March 2008)

"Leukemia Lymphoma Society." Presented at Annual Fund Raiser, . (June 2008)

"Finding and Negotiating a Laboratory-Based Academic Position in Hematology/Oncology." Columbus, OH. (December 2008)

"Overview of viral oncogenesis." Presented at Integrated Biomedical Graduate Program, . (February 2008)

"Immune deficiency and cancer.." Presented at Internal Medicine Residency Block Conference Series, . (February 2008)

"EBV infection promotes epigenetic silencing of tumor suppresor genes that alter the microenvironment.." Presented at 11th Annual Meeting of the Translational Research Cancer Center Consortium, Morgantown, WV. (February 2008)

"PTLD Overview. Pathogenesis and Management." Presented at Comprehensive Transplant Center Series. Clinical Pathology Conference, Columbus, OH. (October 2008)

"Management of PTLD at OSU." Columbus, OH. (January 2009)

"Management of Primary CNS PTLD at OSU." Columbus, OH. (March 2009)

"HIV and Cancer. Challenges and Opportunities.." Presented at HIV Community Forum and Health Fair, Columbus, OH. (November 2009)

"Pennies for Patients Fund Drive." Columbus, OH. (May 2009)

"Animal Models of Disease. How do we know they apply to humans?." Columbus, OH. (May 2009)

"Vaccine Strategies to Prevent EBV-Associated Post Transplant lymphomas." Columbus, OH. (February 2009)

"Infection, Inflammation and Cancer." Columbus, OH. (April 2009)

"HIV/AIDS and Cancer." Presented at Columbus Public Health Department Forum, Columbus, OH. (October 2010)

"Discovery of small molecule inhibitors to target PRMT5 over expression in mantle cell lymphoma." Presented at Mantle Cell Lymphoma Conference, Atlanta, GA. (April 2010)

"HIV+ Lymphoma." Presented at Oncology Nursing Society Community Outreach Committee Seminar, Columbus, OH. (August 2010)

"Potential for a vaccine approach to prevention of EBV-associated malignancy." Presented at AACR - The Science of Cancer Health Disparities Conference, Washington, DC. (September 2011)

""Discovering Novel Targets for Mantle Cell Lymphoma"." Presented at International Association for Comparative Research on Leukemia and Related Diseases (IACRLRD), Tokyo, JP|JPN. (September 2011)

"Enzyme Protein Arginine Methyltransferase 5 (PRMT5) as a Target in MCL." Presented at 2011 Mantle Cell Lymphoma Scientific Workshop, Crystal City, VA. (March 2011)

"Developing Strategies to Target Novel Pathways in Cancer PRMT5, Arginine Methylation and Cancer." Presented at Translational Pharmacology: Practical Pharmacokenitic and Pharmacodynamic Considerations in Pre-Clinical and Clinical Drug Development, Columbus, OH. (April 2011)

"Developing Strategies to Fund Research to Enhance Minority Patient Access to AMC Clinical Trials." Presented at Spring Investigator's Meeting AIDS Malignancy Consortium, Los Angeles, CA. (April 2011)

"Successful Research Panel." Presented at Medical Student Research Scholarship Orientation, Columbus, OH. (June 2011)

"Mechanism of Viral Oncogenesis and EBV Associated Disease." Presented at Viral Oncology Program Retreat, Columbus, OH. (June 2011)

""Targeting PRMT5 and Lymphoma"." Presented at Experimental Therapeutics Seminar, Columbus, OH. (October 2011)

"Lymphoma Research Foundation, Ask the Doctor." Columbus, OH. (December 2011)

 

Professional Activities

2008 - present Free Medical Clinic. Xenos / Youth for Christ Free Medical Clinic. Columbus, OH.
2008 - present AIDS Clinical Trials Unit and AIDS Malignancy Consortium Community Advisory Board. ACTU/AMC Community Advisory Board. Columbus, OH.
2009 - present Ohio ACP Students and Associates Abstract Competition. American College of Physicians Ohio Chapter. Columbus, OH.
2011 - present Cover Story and Photo. "HemOnc Today" Clinical News in Hematology and Oncology.
2011 - present Letter of Intent Review Process ad hoc member Research Evaluation and Decision Panel (REDP). Aids and Cancer Specimen Resource (ACSR).
2011 - present OSU Medical Center Annual Research Day Poster. The Ohio State University Medical Center.
2011 - present American Cancer Society's Institutional Rsearch Grant. American Cancer Society.
2008 - 2010 OSU Post Transplant Lymphoproliferative Disorder Focus Group. PTLD Focus Group. Columbus, OH.
 

Unpublished Works

Yan F, Alinari L, Lustberg M, Martin K, Cordero-Nieves H, Wojton J, b Naduparambil J, Chakravarti A, Nowicki M, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton J, Smith P, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon C-H, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA. Targeting Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Over Expression in High Grade Astrocytomas. February 2013.

Cohen JB, Ruppert AS, Heerema NA, Kaplan LD, Bartlett N, Shea T, Damon LE, Elder P, Baiocchi RA, Porcu P, Flynn JM, Penza S, Jones JA, Christian BA, Blum KA, Devine SM, Andritsos LA. Complex Karyotype is Associated with Shortened Progression-Free Survival and Increased Cumulative Incidence of Relapse Following Autologous Stem Cell Transplantation for Mantle Cell Lymphoma. March 2013.

Stephens DM, Ruppert AS, Maddocks K, Andritsos L, Baiocchi RA, Jones J, Johnson AJ, Smith LL, Zhao Y, Ling Y, Li J, Phelps MA, Grever MR, Byrd JC, Flynn JM. Phase I Feasibility Trial of Cyclophosphamide, Alvocidib (Flavopiridol) and Rituximab (CAR) in Patients with High-Risk B-cell Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL). May 2013.

Jones J, Andritsos L, Baiocch RA, Benson D, Blum K, Christian B, Flynn J, Stark A, Phelps M, Porcu P, Grever MR, Ming P, Byrd JC. Flavopiridol Can Be Safely Administered Using a Pharmacologically Derived Schedule and Demonstrates Activity in Relapsed and Refractory Non-Hodgkin’s Lymphoma. April 2013.

Patton JT, Lustberg ME, Lozanski G, Garmin S, Towns WH, Drohan CM, Lehman A, Zhang X, Bolon B, Li P, Kinghorn AD, Grever MR, Lucas DM, Baiocchi RA. Silvestrol modulated direct and indirect anti-tumor activity against Epstein-Barr Virus-driven lymphoproliferative disease. July 2013.

Nicholas C, Yang J, Peters, Bill MA, Baiocchi RA, Yan F, Sif S, Tae S, Grever MR, Young GS, Lesinski GB. PRMT5 is Upregulated in Malignant and Metastatic Melanoma, and Regulates Expression MITF and p27. March 2013.

Cohen J. Geyer S. Lozanski G, Zhao W, Heerema N, Hall N, Nagar V. Hemminger J, Jones JA, Procu P. Christian B, Baiocchi RA, Maddocks K, Flynn JM, Devine S, Blum KA. omplete Response to Induction Therapy in Patients with Myc+ and Double Hit non-Hodgkin’s Lymphoma is Associated with Prolonged Progression-Free Survival. June 2013.

Patton JT, Lustberg ME, Lozanski G, Garmin S, Towns WH, Drohan CM, Lehman A, Zhang X, Bolon B, Li P, Kinghorn AD, Grever MR, Lucas DM, Baiocchi RA. Complete Response to Induction Therapy in Patients with Myc+ and Double Hit non-Hodgkin’s Lymphoma is Associated with Prolonged Progression-Free Survival. June 2013.

Cohen J, Stark A, Heerema N, Andritsos LA, Jones JA, Porcu P, Baiocchi RA, Christian B, Byrd JC, Flynn JM, Penza S, Devine S, Blum KA.. Complex karyotype is associated with aggressive disease and shortened progression-free survival in patients with newly diagnosed mantle cell lymphoma. May 2013.

Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers L, Agostinelli C, Sileri S, Denis G, Baiocchi RA, Sif S. PRMT5 inhibition induces death of lymphoma cells through reactivation of the retinoblastoma tumor suppressor pathway and silencing of the PRC2 complex. May 2013.