The OSUMC Division of Human Genetics and Center for Personalized Health Care along with the the Coriell Institute for Medical Research is using an integrated approach to recruiting study participants for a personalized genomics study focusing on the effect genetic counseling related to personal genomic test results has on patients with chronic disease. This study plans to enroll 1,800 patients at OSUMC into the Coriell Personalized Medicine Collaborative (CPMC). Those enrolled will constitute the largest randomized research project of the CPMC to date, studying how genetic counseling impacts the way patients respond to personal risk information for diseases, such as melanoma and age-related macular degeneration. Ohio State is the first institution to involve physicians and their patients with heart disease or hypertension in this process. Study investigators are targeting two specific groups of patients. Physicians from Ohio State’s Ross Heart Hospital are helping to recruit 900 patients with congestive heart failure (CHF), and OSU internal medicine physicians will help with the recruitment of 900 patients with hypertension. Investigators also want to study whether genetic data is effective at differentiating patients with CHF who respond to treatment compared to CHF patients who are non- responders to a standard treatment regimen. In addition, investigators want to find out whether genetic data are effective at predicting which newly diagnosed patients with high blood pressure will require adjustments to medications.