2001 Polaris Pkwy
Columbus, OH 43240
Phone: (614) 293-9099
Associate Professor-Clinical, Human Genetics
Ms. Nagy’s undergraduate training was completed at the University of Iowa in Iowa City, IA. She graduated in 1992 with a Bachelor’s of Science in Biology with a minor in English. She then was a Research Assistant in the Department of Physiology and Biophysics at the University of Iowa, where she worked for 2 years on gene transcription in Drosophila melanogaster. In June 1996, she completed her Master’s of Science in Genetic Counseling at the University of Minnesota in Minneapolis, MN. In June 1999, she received her Board Certification from the American Board of Genetic Counseling. Between July 1996 and October 2002, Ms. Nagy was a Genetic Counselor in the Center for Human Genetics at Case Western Reserve University/University Hospitals of Cleveland in Cleveland, Ohio. In 1999, she was appointed to Clinical Instructor of Medicine. She then came to The Ohio State University in October 2002 as a Genetic Counselor and Clinical Instructor of Medicine in the Clinical Cancer Genetics Program in the Division of Human Genetics, Department of Internal Medicine. She was promoted to Clinical Assistant Professor of Internal Medicine in 2005. In 2010 she was appointed Assistant Professor, Clinical Internal Medicine. Ms. Nagy’s clinical responsibilities include counseling patients and families with a variety of different cancer susceptibility syndromes about cancer risks, genetic testing, and medical management. In addition to her clinical duties, Ms. Nagy is the Study Coordinator for the Familial Papillary Thyroid Cancer gene hunting study as well as the Endocrine Neoplasia Repository Study and is a Co-investigator on the NCI-funded program project "Genetic Signaling Pathways in Epithelial Thyroid cancer, led by PI, Matthew D. Ringel, MD. She is also active in the National Society of Genetic Counselors (NSGC) serving as Co-chair of the Cancer Special Interest Group between 2007-2009 and then as NSGC Secretary Treasurer in 2010 (elect) and 2011.
|1999 - present||Diplomate: American Board of Genetic Counseling|
|1992||B.S., University of Iowa|
|1996||M.S., University of Minnesota|
|2002 - 2005||Journal of Medical Genetics|
|2004 - present||NCI Physician Data Query (PDQ) Cancer Genetics editorial board|
|2010 - present||Thyroid|
|2011 - present||Genetics in Medicine|
|2011 - present||Frontiers in Thyroid Endocrinology|
|2011 - present||Journal of Genetic Counseling|
|2010 - present||NIH Award of Merit. National Institutes of Health.|
Anderson MG; Perkins GL; Chittick P; Shrigley RJ; Johnson WA. "drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia.." Genes & Development. Vol. 9, no. 1. (January 1995.): 123-.
Certel K; Anderson MG; Shrigley RJ; Johnson WA. "Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea.." Molecular And Cellular Biology. Vol. 16, no. 4. (April 1996.): 1813-.
Rose PG; Shrigley R; Wiesner GL. "Germline BRCA2 mutation in a patient with fallopian tube carcinoma: a case report.." Gynecologic Oncology. Vol. 77, no. 2. (May 2000.): 319-.
Nagy R; Sweet K; Eng C. "Highly penetrant hereditary cancer syndromes.." Oncogene. Vol. 23, no. 38. (August 2004.): 6445-.
He H; Olesnanik K; Nagy R; Liyanarachchi S; Prasad ML; Stratakis CA; Kloos RT; de la Chapelle A. "Allelic variation in gene expression in thyroid tissue.." Thyroid: Official Journal Of The American Thyroid Association. Vol. 15, no. 7. (July 2005.): 660-.
He H; Jazdzewski K; Li W; Liyanarachchi S; Nagy R; Volinia S; Calin GA; Liu CG; Franssila K; Suster S; Kloos RT; Croce CM; de la Chapelle A. "The role of microRNA genes in papillary thyroid carcinoma.." Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 102, no. 52. (December 2005.): 19075-.
Yoon H; He H; Nagy R; Davuluri R; Suster S; Schoenberg D; Pellegata N; Chapelle Ade L. "Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest.." International Journal Of Cancer. Journal International Du Cancer. Vol. 121, no. 4. (August 2007.): 767-.
Leib J, Hoodfar E, Larsen Haidle J, Nagy R. "The new genetic privacy law: How GINA will affect patients seeking counseling and testing for inherited cancer risk.." Community Oncology. Vol. 5, no. 6. (January 2008.): 351-354.
Gudmundsson J; Sulem P; Gudbjartsson DF; Jonasson JG; Sigurdsson A; Bergthorsson JT; He H; Blondal T; Geller F; Jakobsdottir M; Magnusdottir DN; Matthiasdottir S; Stacey SN; Skarphedinsson OB; Helgadottir H; Li W; Nagy R; Aguillo E; Faure E; Prats E; Saez B; Martinez M; Eyjolfsson GI; Bjornsdottir US; Holm H; Kristjansson K; Frigge ML; Kristvinsson H; Gulcher JR; Jonsson T; Rafnar T; Hjartarsson H; Mayordomo JI; de la Chapelle A; Hrafnkelsson J; Thorsteinsdottir U; Kong A; Stefansson K. "Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.." Nature Genetics. Vol. 41, no. 4. (April 2009.): 460-.
He H; Nagy R; Liyanarachchi S; Jiao H; Li W; Suster S; Kere J; de la Chapelle A. "A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24.." Cancer Research. Vol. 69, no. 2. (January 2009.): 625-.
Paes JE; Hua K; Nagy R; Kloos RT; Jarjoura D; Ringel MD. "The relationship between body mass index and thyroid cancer pathology features and outcomes: a clinicopathological cohort study.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 95, no. 9. (September 2010.): 4244-.
Westman JA; Ferketich AK; Kauffman RM; MacEachern SN; Wilkins JR 3rd; Wilcox PP; Pilarski RT; Nagy R; Lemeshow S; de la Chapelle A; Bloomfield CD. "Low cancer incidence rates in Ohio Amish.." Cancer Causes & Control: CCC. Vol. 21, no. 1. (January 2010.): 69-.
Iuliano R; Palmieri D; He H; Iervolino A; Borbone E; Pallante P; Cianflone A; Nagy R; Alder H; Calin GA; Trapasso F; Giordano C; Croce CM; de la Chapelle A; Fusco A. "Role of PTPRJ genotype in papillary thyroid carcinoma risk.." Endocrine-Related Cancer. Vol. 17, no. 4. (October 2010.): 1001-.
He H; Liyanarachchi S; Akagi K; Nagy R; Li J; Dietrich RC; Li W; Sebastian N; Wen B; Xin B; Singh J; Yan P; Alder H; Haan E; Wieczorek D; Albrecht B; Puffenberger E; Wang H; Westman JA; Padgett RA; Symer DE; de la Chapelle A. "Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I.." Science (New York, N.Y.). Vol. 332, no. 6026. (April 2011.): 238-.
Jendrzejewski J, Tomsic J, Lozanski G, Labanowska J, He H, Liyanarachchi S, Nagy R, Ringel MD, Kloos RT, Heerema NA, de la Chapelle A. "Telomere Length and Telomerase Reverse Transcriptase Gene Copy Number in Patients with Papillary Thyroid Carcinoma." Journal of Clinical Endocrinology and Metabolism. Vol. 96, no. 11. (November 2011.): E1786-1880.
Nagy R, Ganapathi S, Comeras I, Peterson C, Orloff M, Porter K, Eng C, Ringel M, Kloos RT.. "Frequency of germline PTEN mutations in differentiated thyroid cancer." Thyroid. Vol. 21, no. 5. (May 2011.): 505-510.
Pilarski R, Nagy R.. "Genetic testing by cancer site: endocrine.." Cancer Journal. Vol. 18, no. 4. (July 2012.): 364-371.
Nagy R, Wang H, Albrecht B, Wieczorek D, Gillessen-Kaesbach G, Haan E, Meinecke P, de la Chapelle A, Westman J.. "Microcephalic osteodysplastic primordial dwarfism type I with biallelic mutations in the RNU4ATAC gene.." Clinical Genetics. Vol. 82, no. 2. (August 2012.): 140-146.
Shen R, Liyanarachchi S, Li W, Wakely PE, Saji M, Huang J, Nagy R, Farrell T, Ringel MD, de la Chapelle A, Kloos RT, He H. "MicroRNA Signature in Thyroid Fine Needle Aspiration Cytology Applied to "Atypia of Undetermined Significance" Cases.." Thyroid. Vol. 22, no. 1. (January 2012.): 9-16.
Gudmundsson J, Sulem P, Gudbjartsson DF, Jonasson JG, Masson G, He H, Jonasdottir A, Sigurdsson A, Stacey SN, Johannsdottir H, Helgadottir HT, Li W, Nagy R, Ringel MD, Kloos RT, de Visser MC, Plantinga TS, den Heijer M, Aguillo E, Panadero A, Prats E, Garcia-Castaño A, De Juan A, Rivera F, Walters GB, Bjarnason H, Tryggvadottir L, Eyjolfsson GI, Bjornsdottir US, Holm H, Olafsson I, Kristjansson K, Kristvinsson H, Magnusson OT, Thorleifsson G, Gulcher JR, Kong A, Kiemeney LA, Jonsson T, Hjartarson H, Mayordomo JI, Netea-Maier RT, de la Chapelle A, Hrafnkelsson J, Thorsteinsdottir U, Rafnar T, Stefansson K.. "Discovery of common variants associated with low TSH levels and thyroid cancer risk.." Nature Genetics. Vol. 44, no. 3. (January 2012.): 319-322.
Riley BD, Culver JO, Skrzynia C, Senter LA, Peters JA, Costalas JW, Callif-Daley F, Grumet SC, Hunt KS, Nagy R, McKinnon WC, Petrucelli NM, Bennett RL, Trepanier AM.. "Essential Elements of Genetic Cancer Risk Assessment, Counseling, and Testing: Updated Recommendations of the National Society of Genetic Counselors.." Journal of Genetic Counseling. Vol. 21, no. 2. (April 2012.): 151-161.
Jendrzejewski J, He H, Radomska HS, Li W, Tomsic J, Liyanarachchi S, Davuluri RV, Nagy R, de la Chapelle A. "The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.." Proceedings of the National Academy of Science USA. Vol. 109, no. 22. (May 2012.): 8646-8651.
He H, Li W, Wu D, Nagy R, Liyanarachchi S, Akagi K, Jendrzejewski J, Jiao H, Hoag K, Wen B, Srinivas M, Waidyaratne G, Wang R, Wojcicka A, Lattimer IR, Stachlewska E, Czetwertynska M, Dlugosinska J, Gierlikowski W, Ploski R, Krawczyk M, Jazdzewski K, Kere J, Symer DE, Jin V, Wang Q, de la Chapelle A.. "Ultra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance.." PLoS One. Vol. 8, no. 5. (May 2013.): e61920-.
"Chromosomal Abnormalities in Pregnancy: Case Reports." Presented at Mt. Sinai Medical Center OB/GYN Grand Rounds, . (March 1997)
"Cancer Genetic Counseling." Presented at Great Lakes Regional Genetics Group Annual Meeting, . (April 1997)
"Genetic Diseases in the Jewish Population." Presented at Temple Emanuel Monthly Meeting, . (March 1998)
"Genetic Testing and Insurance." Presented at The Jewish Community Federation Annual Meeting, . (June 1998)
"Genetic Testing for Breast Cancer: What It Means for You and Your Family.." Presented at Hadassah of Cleveland Quarterly Meeting, . (April 1999)
"The Genetics of Prostate Cancer." Presented at In Good Company: Prostate Cancer Support Group Monthly Meeting, . (July 2000)
"Breast Cancer Risk and Prevention: What are Your Choices?." Presented at Annual Retreat at The Gathering Place, . (October 2000)
"Cancer Genetic Counseling: Teaching Aids." Presented at Great Lakes Regional Genetics Group Annual Meeting, . (May 2000)
"The Genetics of Prostate Cancer." Presented at In Good Company: Prostate Cancer Support Group Monthly Meeting, . (March 2001)
"Impact of genetic discrimination on BRCA testing and medical management decisions.." Presented at American Society of Human Genetics Annual Meeting, . (January 2002)
"Low cancer incidence rates in Ohio Amish.." Presented at American Society of Human Genetics Annual Meeting, . (January 2003)
"Hereditary Breast Ovarian Cancer." Presented at Industry-sponsored CME Event, . (November 2003)
"Novel Approach to Improved Access to Cancer Genetic Services: the Columbus, Ohio Solution.." Presented at American Society of Human Genetics Annual Meeting, . (January 2003)
"Hereditary Breast and Colon Cancer Syndromes." Presented at Marion General Hospital Grand Rounds, . (January 2004)
"Breast Cancer Genetics 101." Presented at Grant Medical Center Surgery Grand Rounds, . (December 2004)
"Familial Cancer Risk Assessment." Presented at American Cancer Society Patient Navigator Quarterly Meeting, . (May 2005)
"An Update on Familial Non-Medullary Thyroid Cancer." Presented at National Society of Genetic Counselors Annual Education Conference, Los Angeles, CA. (November 2005)
"Breast Cancer Genetics." Presented at Annual Meeting of Breast and Cervical Cancer Project Coordinators, . (May 2006)
"An Update on Colon Cancer Genetics." Presented at Ohio-Wide ACS Colon Cancer Summit, . (March 2007)
"Genetics in Medicine in the 21st Century." Presented at Ohio Ministries Convocation Annual Meeting, . (January 2007)
"Cancer Genetics 101." Presented at Fairfield Medical Center Grand Rounds, . (August 2007)
"Ethical, Legal, and Social Issues in Cancer Genetic Testing." Presented at Genesis Healthcare Grand Rounds, . (February 2008)
"Genetic Testing for Hereditary Cancer Susceptibility." Presented at Southern Ohio Medical Center Grand Rounds, . (January 2008)
"The Genetic Non-discrimination Act (GINA): Implications for Our Patients." Presented at Ohio Genetic Counselors Semi-annual Meeting, . (September 2008)
"Frequency of PTEN Mutations in Unselected Cancer Cohorts." Presented at National Society of Genetic Counselors Annual Education Conference, Los Angeles, CA. (October 2008)
"An Update on Familial Non-Medullary Thyroid Cancer." Presented at National Society of Genetic Counselors Annual Education Conference, Los Angeles, CA. (October 2008)
"BRCA Testing in the DTC Era." Presented at ACOG Ohio Directors Meeting, . (October 2009)
"Ovarian Cancer." Presented at Ovarian Cancer Charity Banquet, . (November 2009)
"Frequnecy of germline PTEN mutations in differentaited thyroid cancer.." Presented at International Thyroid Congress, Paris, FR|FRA. (September 2010)
"Familial non-medullary thyroid cancer.." Presented at 2010 Annual Thyroid Cancer Survivors Meeting, Dallas, TX. (October 2010)
"Immunohistochemistry for the Detection of Lynch Syndrome." Presented at Genesis Healthcare Grand Rounds, . (January 2010)
"Cancer Genetic Counseling and Risk Assessment: Illustrative Cases." Presented at Ohio 2010 Collaborative Laboratory Conference, . (April 2010)
"Lynch Syndrome Screening: From Population Studies to Practice." Presented at Ohio-wide ACS Colon Cancer Summit, . (March 2011)
|2009 - present||Myriad Genetic Laboratories Advisory Board on Genetic Counseling: Alternative Service Delivery Models. Myriad Genetics Labs, Inc.. Salt lake City, UT.|
|2006 - 2009||Mentor for Undergraduate Student Amanda Knoth. The Ohio State University.|
|2007 - 2009||Grant reviewer. National Society of Genetic Counselors.|
|2008 - 2011||Mentor for undergraduate student Brandon Smith. The Ohio State University.|