Kirk Mykytyn, PhD
Phone: (614) 292-4985
mykytyn.1@osu.edu

Selected Publications
Bishop GA, Berbari NF, Lewis JS, Mykytyn K. Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain. (2007) J Comp Neurol 505, 562-571.

Mokrzan E, Lewis, JS, Mykytyn K. Differences in renal tubule primary cilia length in a mouse model of Bardet-Biedl syndrome. (2007) Nephron Exp Nephrol 106, 88-96.

Mykytyn K. Clinical variability in ciliary disorders. (2007) Nature Genetics 39, 818-819.

Berbari NF, Bishop GA, Askwith CC, Lewis JS, Mykytyn K. Hippocampal neurons possess primary cilia in culture. (2007) J Neurosci Res 85, 1095-1100. (cover illustration)

Mykytyn K, Sheffield VC. Establishing a connection between cilia and Bardet-Biedl syndrome. (2004) Trends in Molecular Medicine 10, 106-109.

Nishimura DY, Fath M, Mullins RF, Searby C, Andrews M, Davis R, Andorf JL, Mykytyn K, Swiderski RE, Yang B, Carmi R, Stone EM, Sheffield VC. Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin. (2004) Proc Natl Acad Sci U S A 101, 16588-93.

Mykytyn K, Mullins RF, Andrews M, Chiang AP, Swiderski RE, Yang B, Braun T, Casavant T, Stone EM, Sheffield VC. Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. (2004) Proc Natl Acad Sci U S A 101, 8664-8669.

Mykytyn K, Nishimura DY, Searby CC, Beck G, Bugge K, Haines HL, Cornier AS, Cox GF, Fulton AB, Carmi R, Iannaccone A, Jacobson SG, Weleber RG, Wright AF, Riise R, Hennekam RCM, Lüleci G, Berker-Karauzum S, Biesecker LG, Stone EM, Sheffield VC. Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1). (2003) Am J Hum Genet 72, 429-437.

Mykytyn K, Nishimura DY, Searby CC, Shastri M, Yen H, Beck JS, Braun T, Streb LM, Cornier AS, Cox GF, Fulton AB, Carmi R, Lüleci G, Chandrasekharappa SC, Collins FS, Jacobson SG, Heckinlively JR, Weleber RG, Stone EM, V.C. Sheffield. Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome. (2002) Nature Genetics 31, 435-438.

Mykytyn K, Braun T, Carmi R, Haider NB, Searby CC, Shastri M, Beck G, Wright AF, Iannaccone A, Elbedour K, Riise R, Baldi A, Raas-Rothschild A, Gorman SW, Duhl DM, Jacobson SG, Casavant T, Stone EM, Sheffield VC. Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. (2001) Nature Genetics 28, 188-191.