Current OSU Appointment

Assistant Professor-Clinical, General Internal Medicine

Abstracts

Mary Michaelis, Guibin Li, Alexander Fibuschevich, Rick Dobrowsky. 2002. "Potentail mechanisms underlying the protective effects of taxol against A-Beta-induced toxicity in primary neurons." Abstract.  Neurobiology of Aging, 23: S504.

Therasa Kannanayakal, Haishan Yin, Qi Zhony, Guibin Li, Jeff Kuret. 2004. "Casein kinase 1 phosphorylates and colocalizes with lesions in Alzheimer's disease and inclusion body in myositis." Abstract.  Neurobiology of Aging, 25: S430.

Certifications

2008 - present

Board Certified: Internal Medicine, American Board of Internal Medicine

Chapters In Books

Guibin Li. 1996. A Comprehensive Cannon of Diagnosis and Treatment. In Children's Blood Diseases. Hebei: He Bei Scientific Press.

Degrees

1983	M.D., Hebei Medical College, Medicine

2002	Ph.D., University of Kansas, Pharmacology and Toxicology

Fellowship, Internship or Residency

08/83 - 07/88

Residency, Pediatrics, Hebei Medical College, Shijiazhuang, Hebei, China.

09/02 - 05/05

Postdoctoral Fellowship, Neurobiology, The Ohio State University, Columbus, OH, United States.

07/05 - 06/08

Residency, Internal Medicine, Mount Carmel Medical Center, Columbus, OH, United States.

07/08 - 06/09

Fellowship, Geriatrics, University of Michigan, Ann Arbor, MI, United States.

Honors

1978 - 1983

Merit Scholarship for Medical Students. Hebei Medical College, Shijiazhuang, Hebei, China.

1993	Award for Excellence in Clinical Work. Hebei Medical College, Shijiazhuang, Hebei, China.

1994	Public Health Bureau Award. Hebei Province, Hebei, China.

1995	Award for Excellence in Clinical Work. Hebei Medical College, Shijiazhuang, Hebei, China.

1995 - 1996

Award for Excellence in Teaching. Hebei Medical College, Shijiazhuang, Hebei, China.

1997	Award for Excellence in Clinical Work. Hebei Medical College, Shijiazhuang, Hebei, China.

1999 - 2002

Goetch Scholarship. University of Kansas, Lawrence, KS, United States.

2001	Dean's Honor Roll. University of Kansas, Lawrence, KS, United States. Subject: Pharmacy

Peer Reviewed Journal Articles

Guibin Li, Wenjie Guo. 1992. The value of G-6-PD in the diagnosis of iron deficiency.  Chinese Journal of Pediatrics, no. 30: 40.

Guibin Li, Wenjie Guo, Yuemei Li. 1996. Clinical research in pediatric ITP.  Medical Journal of Hebei, no. 18: 1-5.

Mary Michaelis, Rick Dobrowsky, Guibin Li. 2002. Tau neurofibrillary pathology and microtubule stability.  Journal of Molecular Neuroscience, no. 19: 289-93.

Guibin Li, Alexander Faibushevich, Bradon J. Turunen, Sung Ok Yoon, Gunda Georg, Mary L. Michaelis, Rick T. Dobrowsky. 2003. Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons.  Journal of Neurochemistry, no. 84: 347-62.

John Antonio Chavez, Trina Knotts, Li-Ping Wang, Guibin Li, Rick Dobrowsky, Gregory Florant, Scott Summers. 2003. A role for ceramide, but not diacylglycerol, n the antagonism of insulin signal transduction by saturated fatty acids.  Journal of Biological Chemistry, no. 278: 10297-303.

Guibin Li, Haishan Yin, Jeff Kuret. 2004. Casein kinase 1 delta phosphorylates tau and disrupts in binding to microtubules.  Journal of Biological Chemistry, no. 279: 15938-45.

Jeff Kuret, Carman Chirita, Erin Congdon, Teresa Kannanayakal, Guibin Li, Mihela Necula, Haishan Yin, Qi Zhong. 2005. Pathways of tau fibrillization.  Biochimica et Biophysica Acta, no. 1739: 167-78.

Jeff Kuret, Carmen Chirita, Erin Congdon, Thersa Kannanayakal, Guibin Li, Mihaela Necula, Haishan Yin, Qi Zhong. 2005. Pathways of tau fibrillization.  Biochimica et Biophysica Acta: 167-178.

Jeff Kuret, Erin Congdon, Guibin Li, Haishan Yin, Xian Yu, Qi Zhong. 2005. Evaluating triggers and enhancers of tau fibrillization.  Microscopy Research and Technique, no. 67: 141-55.

Haishan Yin, Laguna KA, Guibin Li, Jeff Kuret. 2006. Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.  Biochemistry, no. 45: 5297-308.

Bhaswati Bandyopadhyay, Guibin Li, Haishan Yin, Jeff Kuret. 2007. Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy.  Journal of Biological Chemistry. Vol. 282, no. 22: 16454-16464.

Kathleen Seyb, Sabah Ansar, Guibin Li, Jennifer Bean, Mary Michaelis, Rick Dobrowsky. 2007. Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide.  Journal of Molecular Neuroscience. Vol. 31, no. 1: 23-35.

Positions

1988 - 1995

Attending Physician & Assistant Professor, Hebei Medical College, Department of Pediatrics, the Second Affiliated Hospital. Shijiazhuang, Hebei, China.

1995 - 1997

Associate Professor, Hebei Medical College, Department of Pediatrics, the Second Affiliated Hospital. Shijiazhuang, Hebei, China.

1998 - 2002

Graduate Research Assistant, University of Kansas, Department of Pharmacology & Toxicology. Lawrence, KS, United States.

2009 - present

Assistant Professor of Clinical Medicine, The Ohio State University College of Medicine, Department of Internal Medicine/Division of General Internal Medicine. Columbus, OH, United States.

Presentations

Other Presentations

Local

Guibin Li, Yuemei Li, Wenjie Guo. 1996. The effect of traditional medicine on the progress of ITP in Children (Abstract). Presented at The Fourth Chinese-Japanese Symposium on Coagulation, Fibrinolysis and Platelet. (October)

Guibin Li, Haishan Yin, Jeff Kuret. 2004. Casein kinase 1 contributes a major portion of basal tau phosphorylation in situ and modulates its microtubule binding (Abstract). Presented at Neuroscience Meeting. (October)

Haishan Yin, Kelly Threm, Guibin Li, Jeff Kuret. 2004. Identification, purification and characterization of a high-affinity binding protein of casein kinase-1 (Abstract). Presented at Neuroscience Meeting. (October)

Guibin Li, Poster Presenter. 2006. Radiofrequency ablation of liver malignancies. Presented at Ohio Chapter, American College of Physicians Annual Scientific Meeting. Columbus, OH. (October 20)

National

Guibin Li. 1992. Clinical analysis of autoimmune hemolytic anemia in children (Abstract). Presented at The Second National Meeting of Hemolytic Anemia. (August)

Guibin Li, Zhengfang Lang, Wenjie Guo. 1994. Clinical observation of induction treatment for ALL (Abstract). Presented at National Meeting of Leukemia in Children. (October)

Research Interests

03/2006-06/2008: Clinical Research; Radiofrequency ablation of liver malignancies. Mount Carmel Medical Center, Columbus, Ohio