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Motoyasu Saji, MD PhD


Staff photo

420 W 12th Ave, MRF 554A
Columbus, OH 43210

 

Current OSU Appointment

Research Associate Professor, Endo, Diabetes & Metabolism

 

Academic Advising

2012 - present Robert Plews Ohio State University College of Medicine.
 

Degrees

1981 M.D., Hokkaido University

1988 Ph.D., Tokyo Women's Medical College

 

Editorial Activities

2011 - present Frontiers in Thyroid Endocrinology
2012 - present Journal of Clinical Endocrinology and Metabolism
 

Journal Articles

Isozaki O; Tsushima T; Sato K; Saji M; Ohba Y; Emoto N; Sato Y; Shizume K. "Triiodothyronine binding immunoglobulin in a euthyroid man without apparent thyroid disease; its properties and effects on triiodothyronine metabolism.." Acta Endocrinologica. Vol. 108, no. 4. (April 1985.): 498-.

Isozaki O; Tsushima T; Shizume K; Saji M; Ohba Y; Emoto N; Sato K; Sato Y; Kusakabe K. "Thyroid-stimulating antibody bioassay using porcine thyroid cells cultured in follicles.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 61, no. 6. (December 1985.): 1105-.

Sato,K; Fujii,Y; Kasono,K; Saji,M; Tsushima,T; Shizume,K. "STIMULATION OF PROSTAGLANDIN-E2 AND BONE-RESORPTION BY RECOMBINANT HUMAN INTERLEUKIN-1-ALPHA IN FETAL MOUSE BONES." BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Vol. 138, no. 2. (July 1986.): 618-624.

Saji M; Tsushima T; Isozaki O; Murakami H; Ohba Y; Sato K; Arai M; Mariko A; Shizume K. "Interaction of insulin-like growth factor I with porcine thyroid cells cultured in monolayer.." Endocrinology. Vol. 121, no. 2. (August 1987.): 749-.

Emoto,N; Tsushima,T; Shizume,K; Tanaka,T; Saji,M; Ohba,Y; Wakai,K; Arai,M; Ohmura,E. "BIOLOGICAL-ACTIVITIES OF HUMAN GROWTH-HORMONE AND ITS DERIVATIVES ESTIMATED BY MEASURING DNA-SYNTHESIS IN NB2 NODE RAT LYMPHOMA-CELLS." ACTA ENDOCRINOLOGICA. Vol. 114, no. 2. (February 1987.): 283-291.

Saji M; Isozaki O; Tsushima T; Arai M; Miyakawa M; Ohba Y; Tsuchiya Y; Sano T; Shizume K. "The inhibitory effect of iodide on growth of rat thyroid (FRTL-5) cells.." Acta Endocrinologica. Vol. 119, no. 1. (September 1988.): 145-.

Miyakawa M; Saji M; Tsushima T; Wakai K; Shizume K. "Thyroid volume and serum thyroglobulin levels in patients with acromegaly: correlation with plasma insulin-like growth factor I levels.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 67, no. 5. (November 1988.): 973-.

Saji,M; Toshio,T; Arai,M; Tsuchiya,Y; Miyagawa,M; Isozaki,O; Sato,K; Shizume,K. "THYROID STIMULATING ANTIBODY ASSAYED BY IODOTHYRONINE RELEASE INTO MEDIUM USING PORCINE THYROID-CELLS." THYROID 1988. Vol. 796, (January 1988.): 627-630.

Tsushima T; Arai M; Saji M; Ohba Y; Murakami H; Ohmura E; Sato K; Shizume K. "Effects of transforming growth factor-beta on deoxyribonucleic acid synthesis and iodine metabolism in porcine thyroid cells in culture.." Endocrinology. Vol. 123, no. 2. (August 1988.): 1187-.

Nomura K; Suzuki H; Saji M; Horiba N; Ujihara M; Tsushima T; Demura H; Shizume K. "High serum progesterone in hyperthyroid men with Graves' disease.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 66, no. 1. (January 1988.): 230-.

Tahara K; Saji M; Aloj SM; Kohn LD. "The arachidonic acid signal system in the thyroid: regulation by thyrotropin and insulin/IGF-I.." Advances In Experimental Medicine And Biology. Vol. 261, (January 1989.): 295-.

Kohn,L,D; Saji,M; Akamizu,T; Ikuyama,S; Isozaki,O; Kohn,A,D; Santisteban,P; Chan,J,Y; BELLUR,S; Rotella,C,M; Alvarez,F,V; Aloj,S,M. "RECEPTORS OF THE THYROID - THE THYROTROPIN RECEPTOR IS ONLY THE 1ST VIOLINIST OF A SYMPHONY-ORCHESTRA." CONTROL OF THE THYROID GLAND. Vol. 261, (January 1989.): 151-209.

Kohn,L,D; Isozaki,O; Chan,J; Akamizu,T; BELLUR,S; DeLuca,M; Santisteban,P; VARUTTI,A,M; Grimaz,S; Ikuyama,S; Saji,M; Owens,G. "THE THYROTROPIN RECEPTOR IN FRTL-5 THYROID-CELLS - A CLONING APPROACH." FRTL-5 TODAY. Vol. 818, (January 1989.): 77-93.

Kohn LD; Saji M; Akamizu T; Ikuyama S; Isozaki O; Kohn AD; Santisteban P; Chan JY; Bellur S; Rotella CM. "Receptors of the thyroid: the thyrotropin receptor is only the first violinist of a symphony orchestra.." Advances In Experimental Medicine And Biology. Vol. 261, (January 1989.): 151-.

Tsuchiya Y; Saji M; Isozaki O; Arai M; Tsushima T; Shizume K. "Effect of lithium on deoxyribonucleic acid synthesis and iodide uptake in porcine thyroid cells in culture.." Endocrinology. Vol. 126, no. 1. (January 1990.): 460-.

Akamizu T; Saji M; Kohn LD. "A microsequencing approach to identify proteins which appear to interact with thyrotropin in rat FRTL-5 thyroid cells.." Biochemical And Biophysical Research Communications. Vol. 170, no. 1. (July 1990.): 351-.

Akamizu T; Ikuyama S; Saji M; Kosugi S; Kozak C; McBride OW; Kohn LD. "Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.." Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 87, no. 15. (August 1990.): 5677-.

Bellur S; Tahara K; Saji M; Grollman EF; Kohn LD. "Repeatedly passed FRTL-5 rat thyroid cells can develop insulin and insulin-like growth factor-I-sensitive cyclooxygenase and prostaglandin E2 isomerase-like activities together with altered basal and thyrotropin-responsive thymidine incorporation into DNA.." Endocrinology. Vol. 127, no. 3. (September 1990.): 1526-.

Saji M; Kohn LD. "Effect of hydrocortisone on the ability of thyrotropin to increase deoxyribonucleic acid synthesis and iodide uptake in FRTL-5 rat thyroid cells: opposite regulation of adenosine 3',5'-monophosphate signal action.." Endocrinology. Vol. 127, no. 4. (October 1990.): 1867-.

Saji M; Ikuyama S; Akamizu T; Kohn LD. "Increases in cytosolic Ca++ down regulate thyrotropin receptor gene expression by a mechanism different from the cAMP signal.." Biochemical And Biophysical Research Communications. Vol. 176, no. 1. (April 1991.): 94-.

Isozaki O; Tsushima T; Emoto N; Saji M; Tsuchiya Y; Demura H; Sato Y; Shizume K; Kimura S; Kohn LD. "Methimazole regulation of thyroglobulin biosynthesis and gene transcription in rat FRTL-5 thyroid cells.." Endocrinology. Vol. 128, no. 6. (June 1991.): 3113-.

Saji M; Kohn LD. "Insulin and insulin-like growth factor-I inhibit thyrotropin-increased iodide transport in serum-depleted FRTL-5 rat thyroid cells: modulation of adenosine 3',5'-monophosphate signal action.." Endocrinology. Vol. 128, no. 2. (February 1991.): 1136-.

Tahara K; Grollman EF; Saji M; Kohn LD. "Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.." The Journal Of Biological Chemistry. Vol. 266, no. 1. (January 1991.): 440-.

Kohn,L,D; Kosugi,S; Ban,T; Saji,M; Ikuyama,S; Giuliani,C; Hidaka,A; Shimura,H; Akamizu,T; Tahara,K. "Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.." International reviews of immunology. Vol. 9, no. 2. (January 1992.): 135-165.

(January 1992.): 135-.

Saji M; Moriarty J; Ban T; Kohn LD; Singer DS. "Hormonal regulation of major histocompatibility complex class I genes in rat thyroid FRTL-5 cells: thyroid-stimulating hormone induces a cAMP-mediated decrease in class I expression.." Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 89, no. 5. (March 1992.): 1944-.

Saji M; Moriarty J; Ban T; Singer DS; Kohn LD. "Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 75, no. 3. (September 1992.): 871-.

Saji M; Akamizu T; Sanchez M; Obici S; Avvedimento E; Gottesman ME; Kohn LD. "Regulation of thyrotropin receptor gene expression in rat FRTL-5 thyroid cells.." Endocrinology. Vol. 130, no. 1. (January 1992.): 520-.

Kohn,L,D; Ban,T; Okajima,F; Shimura,H; Shimura,Y; Hidaka,A; Giuliani,C; Napolitano,G; Kosugi,S; Ikuyama,S; Saji,M. "RELATIONSHIP OF THE STRUCTURE, FUNCTION, AND REGULATION OF THE THYROTROPIN RECEPTOR TO ITS ROLE IN AUTOIMMUNE THYROID-DISEASE." MOLECULAR BASES OF HUMAN DISEASES. Vol. 1029, (January 1993.): 141-149.

Grollman EF; Saji M; Shimura Y; Lau JT; Ashwell G. "Thyrotropin regulation of sialic acid expression in rat thyroid cells.." The Journal Of Biological Chemistry. Vol. 268, no. 5. (February 1993.): 3604-.

Saji M; Levine MA; Zeiger MA. "An in vitro model of thyroid neoplasia: permanently transfected FRTL-5 cells with thyroglobulin promoter-cholera toxin A1 subunit minigene.." Surgery. Vol. 116, no. 6. (December 1994.): 1048-.

Shimura H; Okajima F; Ikuyama S; Shimura Y; Kimura S; Saji M; Kohn LD. "Thyroid-specific expression and cyclic adenosine 3',5'-monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1.." Molecular Endocrinology (Baltimore, Md.). Vol. 8, no. 8. (August 1994.): 1049-.

Kohn,L,D; Shimura,H; Shimura,Y; Hidaka,A; Giuliani,C; Napolitano,G; Ohmori,M; Laglia,G; Saji,M. "The thyrotropin receptor.." Vitamins and hormones. Vol. 50, (January 1995.): 287-384.

Giuliani C; Saji M; Napolitano G; Palmer LA; Taniguchi SI; Shong M; Singer DS; Kohn LD. "Hormonal modulation of major histocompatibility complex class I gene expression involves an enhancer A-binding complex consisting of Fra-2 and the p50 subunit of NF-kappa B.." The Journal Of Biological Chemistry. Vol. 270, no. 19. (May 1995.): 11453-.

Bifulco M; Perillo B; Saji M; Laezza C; Tedesco I; Kohn LD; Aloj SM. "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. I. Identification and characterization of a cyclic AMP-responsive element in the rat reductase promoter.." The Journal Of Biological Chemistry. Vol. 270, no. 25. (June 1995.): 15231-.

Laglia G; Zeiger MA; Leipricht A; Caturegli P; Levine MA; Kohn LD; Saji M. "Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells.." Endocrinology. Vol. 137, no. 8. (August 1996.): 3170-.

Zeiger MA; Saji M; Caturegli P; Westra WH; Kohn LD; Levine MA. "Transformation of rat thyroid follicular cells stably transfected with cholera toxin A1 fragment.." Endocrinology. Vol. 137, no. 12. (December 1996.): 5392-.

Califano JA; Johns MM 3rd; Westra WH; Lango MN; Eisele D; Saji M; Zeiger MA; Udelsman R; Koch WM; Sidransky D. "An allelotype of papillary thyroid cancer.." International Journal Of Cancer. Journal International Du Cancer. Vol. 69, no. 6. (December 1996.): 442-.

Zeiger MA; Takiyama Y; Bishop JO; Ellison AR; Saji M; Levine MA. "Adenoviral infection of thyroid cells: a rationale for gene therapy for metastatic thyroid carcinoma.." Surgery. Vol. 120, no. 6. (December 1996.): 921-.

Zeiger MA; Saji M; Gusev Y; Westra WH; Takiyama Y; Dooley WC; Kohn LD; Levine MA. "Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice.." Endocrinology. Vol. 138, no. 8. (August 1997.): 3133-.

Schaaf L; Leiprecht A; Saji M; Hübner U; Usadel KH; Kohn LD. "Glycosylation variants of human TSH selectively activate signal transduction pathways.." Molecular And Cellular Endocrinology. Vol. 132, no. 1-2. (September 1997.): 185-.

Takiyama Y; Saji M; Clark DP; Phillips GS; Segev DL; Smallridge RC; Westra WH; Udelsman R; Zeiger MA. "Polymerase chain reaction-based microsatellite analysis of fine-needle aspirations from Hürthle cell neoplasms.." Thyroid: Official Journal Of The American Thyroid Association. Vol. 7, no. 6. (December 1997.): 853-.

Saji M; Shong M; Napolitano G; Palmer LA; Taniguchi SI; Ohmori M; Ohta M; Suzuki K; Kirshner SL; Giuliani C; Singer DS; Kohn LD. "Regulation of major histocompatibility complex class I gene expression in thyroid cells. Role of the cAMP response element-like sequence.." The Journal Of Biological Chemistry. Vol. 272, no. 32. (August 1997.): 20096-.

Umbricht CB; Saji M; Westra WH; Udelsman R; Zeiger MA; Sukumar S. "Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.." Cancer Research. Vol. 57, no. 11. (June 1997.): 2144-.

Saji M; Westra WH; Chen H; Umbricht CB; Tuttle RM; Box MF; Udelsman R; Sukumar S; Zeiger MA. "Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.." Surgery. Vol. 122, no. 6. (December 1997.): 1137-.

Graff JR; Greenberg VE; Herman JG; Westra WH; Boghaert ER; Ain KB; Saji M; Zeiger MA; Zimmer SG; Baylin SB. "Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma.." Cancer Research. Vol. 58, no. 10. (May 1998.): 2063-.

Segev DL; Saji M; Phillips GS; Westra WH; Takiyama Y; Piantadosi S; Smallridge RC; Nishiyama RH; Udelsman R; Zeiger MA. "Polymerase chain reaction-based microsatellite polymorphism analysis of follicular and Hürthle cell neoplasms of the thyroid.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 83, no. 6. (June 1998.): 2036-.

Halachmi N; Halachmi S; Evron E; Cairns P; Okami K; Saji M; Westra WH; Zeiger MA; Jen J; Sidransky D. "Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors.." Genes, Chromosomes & Cancer. Vol. 23, no. 3. (November 1998.): 239-.

Taniguchi SI; Shong M; Giuliani C; Napolitano G; Saji M; Montani V; Suzuki K; Singer DS; Kohn LD. "Iodide suppression of major histocompatibility class I gene expression in thyroid cells involves enhancer A and the transcription factor NF-kappa B.." Molecular Endocrinology (Baltimore, Md.). Vol. 12, no. 1. (January 1998.): 19-.

Ringel,M,D; Schwindinger,W,F; Saji,M; ZEIGER,M,A; Levine,M,A. "Determination of transgene copy number and expression level using denaturing gradient gel electrophoresis." BIOTECHNIQUES. Vol. 24, no. 1. (January 1998.): 126-?.

Montani V; Taniguchi SI; Shong M; Suzuki K; Ohmori M; Giuliani C; Napolitano G; Saji M; Fiorentino B; Reimold AM; Ting JP; Kohn LD; Singer DS. "Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein.." Endocrinology. Vol. 139, no. 1. (January 1998.): 280-.

Montani V; Shong M; Taniguchi SI; Suzuki K; Giuliani C; Napolitano G; Saito J; Saji M; Fiorentino B; Reimold AM; Singer DS; Kohn LD. "Regulation of major histocompatibility class II gene expression in FRTL-5 thyrocytes: opposite effects of interferon and methimazole.." Endocrinology. Vol. 139, no. 1. (January 1998.): 290-.

Ringel MD; Saji M; Schwindinger WF; Segev D; Zeiger MA; Levine MA. "Absence of activating mutations of the genes encoding the alpha-subunits of G11 and Gq in thyroid neoplasia.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 83, no. 2. (February 1998.): 554-.

Chun YS; Saji M; Zeiger MA. "Overexpression of TTF-1 and PAX-8 restores thyroglobulin gene promoter activity in ARO and WRO cell lines.." Surgery. Vol. 124, no. 6. (December 1998.): 1100-.

Saji M; Xydas S; Westra WH; Liang CK; Clark DP; Udelsman R; Umbricht CB; Sukumar S; Zeiger MA. "Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 5, no. 6. (June 1999.): 1483-.

Zeiger MA; Smallridge RC; Clark DP; Liang CK; Carty SE; Watson CG; Udelsman R; Saji M. "Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms.." Surgery. Vol. 126, no. 6. (December 1999.): 1195-.

Dome,J,S; Chung,S; Bergemann,T; Umbricht,C,B; Saji,M; Carey,L,A; Grundy,P,E; Perlman,E,J; Breslow,N,E; Sukumar,S. "High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor." CANCER RESEARCH. Vol. 59, no. 17. (September 1999.): 4301-4307.

Kohn,L,D; Napolitano,G; Singer,D,S; Molteni,M; Scorza,R; Shimojo,N; Kohno,Y; MOZES,E; NAKAZATO,M; Ulianich,L; Chung,H,K; Matoba,H; Saunier,B; Suzuki,K; Schuppert,F; Saji,M. "Graves' disease: a host defense mechanism gone awry.." International reviews of immunology. Vol. 19, no. 6. (January 2000.): 633-664.

Kirshner S; Palmer L; Bodor J; Saji M; Kohn LD; Singer DS. "Major histocompatibility class I gene transcription in thyrocytes: a series of interacting regulatory DNA sequence elements mediate thyrotropin/cyclic adenosine 3',5'-monophosphate repression.." Molecular Endocrinology (Baltimore, Md.). Vol. 14, no. 1. (January 2000.): 82-.

Ringel MD; Greenberg M; Chen X; Hayre N; Suzuki K; Priebat D; Saji M; Burman KD. "Cytotoxic activity of 2',2'-difluorodeoxycytidine (gemcitabine) in poorly differentiated thyroid carcinoma cells.." Thyroid: Official Journal Of The American Thyroid Association. Vol. 10, no. 10. (October 2000.): 865-.

Ringel MD; Hayre N; Saito J; Saunier B; Schuppert F; Burch H; Bernet V; Burman KD; Kohn LD; Saji M. "Overexpression and overactivation of Akt in thyroid carcinoma.." Cancer Research. Vol. 61, no. 16. (August 2001.): 6105-.

Saito J; Kohn AD; Roth RA; Noguchi Y; Tatsumo I; Hirai A; Suzuki K; Kohn LD; Saji M; Ringel MD. "Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling.." Thyroid: Official Journal Of The American Thyroid Association. Vol. 11, no. 4. (April 2001.): 339-.

Siddiqui MT; Greene KL; Clark DP; Xydas S; Udelsman R; Smallridge RC; Zeiger MA; Saji M. "Human telomerase reverse transcriptase expression in Diff-Quik-stained FNA samples from thyroid nodules.." Diagnostic Molecular Pathology: The American Journal Of Surgical Pathology, Part B. Vol. 10, no. 2. (June 2001.): 123-.

Bauer AJ; Terrell R; Doniparthi NK; Patel A; Tuttle RM; Saji M; Ringel MD; Francis GL. "Vascular endothelial growth factor monoclonal antibody inhibits growth of anaplastic thyroid cancer xenografts in nude mice.." Thyroid: Official Journal Of The American Thyroid Association. Vol. 12, no. 11. (November 2002.): 953-.

Kolachana,P; Lawsin,L,M; Saji,M; Moore,J; Ringel,M,D. "Angiotensin II activates growth factor pathways via trans-activation of the EGF receptor in murine mesangial cells.." JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Vol. 13, (September 2002.): 88A-88A.

Germain-Lee,E,L; Ding,C; Crane,J,L; Schwindinger,W,F; Ringel,M; Saji,M; Levine,M,A. "Paternal imprinting of G alpha(s) in the thyroid as the basis for TSH resistance in pseudohypoparathyroidism type IA.." JOURNAL OF BONE AND MINERAL RESEARCH. Vol. 17, (September 2002.): S210-S210.

Germain-Lee EL; Ding CL; Deng Z; Crane JL; Saji M; Ringel MD; Levine MA. "Paternal imprinting of Galpha(s) in the human thyroid as the basis of TSH resistance in pseudohypoparathyroidism type 1a.." Biochemical And Biophysical Research Communications. Vol. 296, no. 1. (August 2002.): 67-.

Ringel MD; Hardy E; Bernet VJ; Burch HB; Schuppert F; Burman KD; Saji M. "Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 87, no. 5. (May 2002.): 2399-.

Bernet VJ; Anderson J; Vaishnav Y; Solomon B; Adair CF; Saji M; Burman KD; Burch HB; Ringel MD. "Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 87, no. 10. (October 2002.): 4792-.

Ramljak, Danica; Coticchia, Christine, M; Nishanian, Tagvor, G; Saji, Motoyasu; Ringel, Matthew, D; Conzen, Suzanne, D; Dickson, Robert B. "Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells.." Experimental cell research. Vol. 287, no. 2. (January 2003.): 397-.

Stabile, Eugenio; Zhou, Yi Fu; Saji, Motoyasu; Castagna, Marco; Shou, Matie; Kinnaird, Timothy, D; Baffour, Richard; Ringel, Matthew, D; Epstein, Stephen, E; Fuchs, Shmuel. "Akt controls vascular smooth muscle cell proliferation in vitro and in vivo by delaying G1/S exit.." Circulation research. Vol. 93, no. 11. (January 2003.): 1059-.

Stabile E; Zhou YF; Saji M; Castagna M; Shou M; Kinnaird TD; Baffour R; Ringel MD; Epstein SE; Fuchs S. "Akt controls vascular smooth muscle cell proliferation in vitro and in vivo by delaying G1/S exit.." Circulation Research. Vol. 93, no. 11. (November 2003.): 1059-.

Bauer, Andrew, J; Patel, Aneeta; Terrell, Richard; Doniparthi, Krishna; Saji, Motoyasu; Ringel, Matthew; Tuttle, R Michael; Francis, Gary L. "Systemic administration of vascular endothelial growth factor monoclonal antibody reduces the growth of papillary thyroid carcinoma in a nude mouse model.." Annals of clinical and laboratory science. Vol. 33, no. 2. (January 2003.): 192-.

Bauer AJ; Patel A; Terrell R; Doniparthi K; Saji M; Ringel M; Tuttle RM; Francis GL. "Systemic administration of vascular endothelial growth factor monoclonal antibody reduces the growth of papillary thyroid carcinoma in a nude mouse model.." Annals Of Clinical And Laboratory Science. Vol. 33, no. 2. (March 2003.): 192-.

Vasko VV; Gaudart J; Allasia C; Savchenko V; Di Cristofaro J; Saji M; Ringel MD; De Micco C. "Thyroid follicular adenomas may display features of follicular carcinoma and follicular variant of papillary carcinoma.." European Journal Of Endocrinology / European Federation Of Endocrine Societies. Vol. 151, no. 6. (December 2004.): 779-.

Perlman, Alan; Lawsin, Loredo, M; Kolachana, Padmaja; Saji, Motoyasu; Moore, Jack Jr; Ringel, Mathew D. "Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.." Annals of clinical and laboratory science. Vol. 34, no. 3. (January 2004.): 277-.

Braga-Basaria, Milena; Hardy, Elena; Gottfried, Robert; Burman, Kenneth, D; Saji, Motoyasu; Ringel, Matthew D. "17-Allylamino-17-demethoxygeldanamycin activity against thyroid cancer cell lines correlates with heat shock protein 90 levels.." The Journal of clinical endocrinology and metabolism. Vol. 89, no. 6. (January 2004.): 2982-.

Umbricht CB; Conrad GT; Clark DP; Westra WH; Smith DC; Zahurak M; Saji M; Smallridge RC; Goodman S; Zeiger MA. "Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.." Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 10, no. 17. (September 2004.): 5762-.

Walker,T; Jensen,K; Saji,M; Ringel,M; Scouten,W; Francis,G. "Iodide inhibits phosphorylation of protein kinase 8 (Akt) and extracellular signal regulated protein kinase (ERK) in FRTL-5 rat thyroid cells." PEDIATRIC RESEARCH. Vol. 55, no. 4. (April 2004.): 141A-141A.

Braga-Basaria M; Hardy E; Gottfried R; Burman KD; Saji M; Ringel MD. "17-Allylamino-17-demethoxygeldanamycin activity against thyroid cancer cell lines correlates with heat shock protein 90 levels.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 89, no. 6. (June 2004.): 2982-.

(September 2004.): 181-.

Miyagi, Eri; Braga-Basaria, Milena; Hardy, Elena; Vasko, Vasily; Burman, Kenneth, D; Jhiang, Sissy; Saji, Motoyasu; Ringel, Matthew D. "Chronic expression of RET/PTC 3 enhances basal and insulin-stimulated PI3 kinase/AKT signaling and increases IRS-2 expression in FRTL-5 thyroid cells.." Molecular carcinogenesis. Vol. 41, no. 2. (January 2004.): 98-.

Vasko, Vasily, V; Gaudart, Jean; Allasia, Claude; Savchenko, Victoria; Di Cristofaro, Julie; Saji, Motoyasu; Ringel, Matthew, D; De Micco, Catherine. "Thyroid follicular adenomas may display features of follicular carcinoma and follicular variant of papillary carcinoma.." European journal of endocrinology / European Federation of Endocrine Societies. Vol. 151, no. 6. (January 2004.): 779-.

Umbricht, Christopher, B; Conrad, George, T; Clark, Douglas, P; Westra, William, H; Smith, Danelle, C; Zahurak, Marianna; Saji, Motoyasu; Smallridge, Robert, C; Goodman, Steven; Zeiger, Martha A. "Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 10, no. 17. (January 2004.): 5762-.

Kada, Faiza; Saji, Motoyasu; Ringel, Matthew D. "Akt: a potential target for thyroid cancer therapy.." Current drug targets. Immune, endocrine and metabolic disorders. Vol. 4, no. 3. (January 2004.): 181-.

Burnett MS; Durrani S; Stabile E; Saji M; Lee CW; Kinnaird TD; Hoffman EP; Epstein SE. "Murine cytomegalovirus infection increases aortic expression of proatherosclerotic genes.." Circulation. Vol. 109, no. 7. (February 2004.): 893-.

Burnett, Mary Susan; Durrani, Sarfraz; Stabile, Eugenio; Saji, Motoyasu; Lee, Cheol, W; Kinnaird, Tim, D; Hoffman, Eric, P; Epstein, Stephen E. "Murine cytomegalovirus infection increases aortic expression of proatherosclerotic genes.." Circulation. Vol. 109, no. 7. (January 2004.): 893-.

Perlman A; Lawsin LM; Kolachana P; Saji M; Moore J Jr; Ringel MD. "Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.." Annals Of Clinical And Laboratory Science. Vol. 34, no. 3. (June 2004.): 277-.

Miyagi E; Braga-Basaria M; Hardy E; Vasko V; Burman KD; Jhiang S; Saji M; Ringel MD. "Chronic expression of RET/PTC 3 enhances basal and insulin-stimulated PI3 kinase/AKT signaling and increases IRS-2 expression in FRTL-5 thyroid cells.." Molecular Carcinogenesis. Vol. 41, no. 2. (October 2004.): 98-.

Vasko V; Saji M; Hardy E; Kruhlak M; Larin A; Savchenko V; Miyakawa M; Isozaki O; Murakami H; Tsushima T; Burman KD; De Micco C; Ringel MD. "Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer.." Journal Of Medical Genetics. Vol. 41, no. 3. (March 2004.): 161-.

Kim CS; Vasko VV; Kato Y; Kruhlak M; Saji M; Cheng SY; Ringel MD. "AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma.." Endocrinology. Vol. 146, no. 10. (October 2005.): 4456-.

Germain-Lee EL; Schwindinger W; Crane JL; Zewdu R; Zweifel LS; Wand G; Huso DL; Saji M; Ringel MD; Levine MA. "A mouse model of albright hereditary osteodystrophy generated by targeted disruption of exon 1 of the Gnas gene.." Endocrinology. Vol. 146, no. 11. (November 2005.): 4697-.

Acharyya S; Butchbach ME; Sahenk Z; Wang H; Saji M; Carathers M; Ringel MD; Skipworth RJ; Fearon KC; Hollingsworth MA; Muscarella P; Burghes AH; Rafael-Fortney JA; Guttridge DC. "Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia.." Cancer Cell. Vol. 8, no. 5. (November 2005.): 421-.

Di Cristofaro J; Vasko V; Savchenko V; Cherenko S; Larin A; Ringel MD; Saji M; Marcy M; Henry JF; Carayon P; De Micco C. "ret/PTC1 and ret/PTC3 in thyroid tumors from Chernobyl liquidators: comparison with sporadic tumors from Ukrainian and French patients.." Endocrine-Related Cancer. Vol. 12, no. 1. (March 2005.): 173-.

Weber, Frank; Shen, Lei; Aldred, Micheala, A; Morrison, Carl, D; Frilling, Andrea; Saji, Motoyasu; Schuppert, Frank; Broelsch, Christoph, E; Ringel, Matthew, D; Eng, Charis. "Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination.." The Journal of clinical endocrinology and metabolism. Vol. 90, no. 5. (January 2005.): 2512-.

Harii, Norikazu; Lewis, Christopher, J; Vasko, Vasilly; McCall, Kelly; Benavides-Peralta, Uruguaysito; Sun, Xiaolu; Ringel, Matthew, D; Saji, Motoyasu; Giuliani, Cesidio; Napolitano, Giorgio; Goetz, Douglas, J; Kohn, Leonard D. "Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.." Molecular endocrinology (Baltimore, Md.). Vol. 19, no. 5. (January 2005.): 1231-.

Germain-Lee, Emily, L; Schwindinger, William; Crane, Janet, L; Zewdu, Rediet; Zweifel, Larry, S; Wand, Gary; Huso, David, L; Saji, Motoyasu; Ringel, Matthew, D; Levine, Michael A. "A mouse model of albright hereditary osteodystrophy generated by targeted disruption of exon 1 of the Gnas gene.." Endocrinology. Vol. 146, no. 11. (January 2005.): 4697-.

Acharyya, Swarnali; Butchbach, Matthew E, R; Sahenk, Zarife; Wang, Huating; Saji, Motoyasu; Carathers, Micheal; Ringel, Matthew, D; Skipworth, Richard J, E; Fearon, Kenneth C, H; Hollingsworth, Michael, A; Muscarella, Peter; Burghes, Arthur H, M; Rafael-Fortney, Jill, A; Guttridge, Denis C. "Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia.." Cancer cell. Vol. 8, no. 5. (January 2005.): 421-.

Weber F; Shen L; Aldred MA; Morrison CD; Frilling A; Saji M; Schuppert F; Broelsch CE; Ringel MD; Eng C. "Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 90, no. 5. (May 2005.): 2512-.

Harii N; Lewis CJ; Vasko V; McCall K; Benavides-Peralta U; Sun X; Ringel MD; Saji M; Giuliani C; Napolitano G; Goetz DJ; Kohn LD. "Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.." Molecular Endocrinology (Baltimore, Md.). Vol. 19, no. 5. (May 2005.): 1231-.

Stathatos N; Bourdeau I; Espinosa AV; Saji M; Vasko VV; Burman KD; Stratakis CA; Ringel MD. "KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity.." The Journal Of Clinical Endocrinology And Metabolism. Vol. 90, no. 9. (September 2005.): 5432-.

Stathatos, Nikolaos; Bourdeau, Isabelle; Espinosa, Allan, V; Saji, Motoyasu; Vasko, Vasily, V; Burman, Kenneth, D; Stratakis, Constantine, A; Ringel, Matthew D. "KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity.." The Journal of clinical endocrinology and metabolism. Vol. 90, no. 9. (January 2005.): 5432-.

Saji, Motoyasu; Vasko, Vasily; Kada, Faiza; Allbritton, Elena Hardy; Burman, Kenneth, D; Ringel, Matthew D. "Akt1 contains a functional leucine-rich nuclear export sequence.." Biochemical and biophysical research communications. Vol. 332, no. 1. (January 2005.): 167-.

Kim, Caroline, S; Vasko, Vasily, V; Kato, Yasuhito; Kruhlak, Michael; Saji, Motoyasu; Cheng, Sheue-Yann; Ringel, Matthew D. "AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma.." Endocrinology. Vol. 146, no. 10. (January 2005.): 4456-.

Saji M; Vasko V; Kada F; Allbritton EH; Burman KD; Ringel MD. "Akt1 contains a functional leucine-rich nuclear export sequence.." Biochemical And Biophysical Research Communications. Vol. 332, no. 1. (June 2005.): 167-.

Giuliani C; Saji M; Bucci I; Fiore G; Liberatore M; Singer DS; Monaco F; Kohn LD; Napolitano G. "Transcriptional regulation of major histocompatibility complex class I gene by insulin and IGF-I in FRTL-5 thyroid cells.." The Journal Of Endocrinology. Vol. 189, no. 3. (June 2006.): 605-.

Porchia LM; Guerra M; Wang YC; Zhang Y; Espinosa AV; Shinohara M; Kulp SK; Kirschner LS; Saji M; Chen CS; Ringel MD. "2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.." Molecular Pharmacology. Vol. 72, no. 5. (November 2007.): 1124-.

Shinohara,Motoo; Chung,Yun,Jae; Saji,Motoyasu; Ringel,Matthew,D. "Minireview: AKT in thyroid tumorigenesis and progression." ENDOCRINOLOGY. Vol. 148, no. 3. (March 2007.): 942-947.

Shinohara M; Chung YJ; Saji M; Ringel MD. "AKT in thyroid tumorigenesis and progression.." Endocrinology. Vol. 148, no. 3. (March 2007.): 942-.

(January 2007.): 11-.

Porchia, Leonardo, M; Guerra, Marcy; Wang, Yu-Chieh; Zhang, Yunlong; Espinosa, Allan, V; Shinohara, Motoo; Kulp, Samuel, K; Kirschner, Lawrence, S; Saji, Motoyasu; Chen, Ching-Shih; Ringel, Matthew D. "2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.." Molecular pharmacology. Vol. 72, no. 5. (January 2007.): -.

McCall, Kelly, D; Harii, Norikazu; Lewis, Christopher, J; Malgor, Ramiro; Kim, Won Bae; Saji, Motoyasu; Kohn, Aimee, D; Moon, Randall, T; Kohn, Leonard D. "High basal levels of functional toll-like receptor 3 (TLR3) and noncanonical Wnt5a are expressed in papillary thyroid cancer and are coordinately decreased by phenylmethimazole together with cell proliferation and migration.." Endocrinology. Vol. 148, no. 9. (January 2007.): -.

Vasko V; Espinosa AV; Scouten W; He H; Auer H; Liyanarachchi S; Larin A; Savchenko V; Francis GL; de la Chapelle A; Saji M; Ringel MD. "Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion.." Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 104, no. 8. (February 2007.): 2803-.

Vasko, Vasily; Espinosa, Allan, V; Scouten, William; He, Huiling; Auer, Herbert; Liyanarachchi, Sandya; Larin, Alexander; Savchenko, Victoria; Francis, Gary, L; de la Chapelle, Albert; Saji, Motoyasu; Ringel, Matthew D. "Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 104, no. 8. (January 2007.): -.

McCall KD; Harii N; Lewis CJ; Malgor R; Kim WB; Saji M; Kohn AD; Moon RT; Kohn LD. "High basal levels of functional toll-like receptor 3 (TLR3) and noncanonical Wnt5a are expressed in papillary thyroid cancer and are coordinately decreased by phenylmethimazole together with cell proliferation and migration.." Endocrinology. Vol. 148, no. 9. (September 2007.): 4226-.

Vasko,Vasyl,V; Saji,Motoyasu. "Molecular mechanisms involved in differentiated thyroid cancer invasion and metastasis." CURRENT OPINION IN ONCOLOGY. Vol. 19, no. 1. (January 2007.): 11-17.

Vasko, Vasyl; Jensen, Kirk; Patel, Aneeta; Saji, Motoyasu; Bauer, Andrew. "The role of Notch signaling in regulation of epithelial to mesenchymal transition in thyroid cancer.." Proceedings of the American Association for Cancer Research Annual Meeting. Vol. 49, (January 2008.): 1276-.

Wang PS; Chou FS; Porchia L; Saji M; Pinzone JJ. "Troglitazone inhibits cell migration, adhesion, and spreading by modulating cytoskeletal rearrangement in human breast cancer cells.." Molecular Carcinogenesis. Vol. 47, no. 12. (December 2008.): 905-.

Wang, Pei-Shan; Chou, Fu-Sheng; Porchia, Leonardo; Saji, Motoyasu; Pinzone, Joseph J.. "Troglitazone Inhibits Cell Migration, Adhesion, and Spreading by Modulating Cytoskeletal Rearrangement in Human Breast Cancer Cells." Molecular Carcinogenesis. Vol. 47, no. 12. (January 2008.): 905-915.

Wang PS; Chou FS; Bloomston M; Vonau MS; Saji M; Espinosa A; Pinzone JJ. "Thiazolidinediones downregulate Wnt/beta-catenin signaling via multiple mechanisms in breast cancer cells.." The Journal Of Surgical Research. Vol. 153, no. 2. (May 2009.): 210-.

Kloos RT; Ringel MD; Knopp MV; Hall NC; King M; Stevens R; Liang J; Wakely PE Jr; Vasko VV; Saji M; Rittenberry J; Wei L; Arbogast D; Collamore M; Wright JJ; Grever M; Shah MH. "Phase II trial of sorafenib in metastatic thyroid cancer.." Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology. Vol. 27, no. 10. (April 2009.): 1675-.

Nadella KS; Saji M; Jacob NK; Pavel E; Ringel MD; Kirschner LS. "Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1.." EMBO Reports. Vol. 10, no. 6. (June 2009.): 599-.

Nadella,Kiran,S; Saji,Motoyasu; Jacob,Naduparambil,K; Pavel,Emilia; Ringel,Matthew,D; Kirschner,Lawrence,S. "Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1 (vol 10, pg 599, 2009)." EMBO REPORTS. Vol. 10, no. 9. (September 2009.): 1066-1066.

Kloos, Richard, K.; Ringel, Matthew, D.; Knopp, Michael, V.; Hall, Nathan, C.; King, Mark; Stevens, Robert; Liang, Jiachao; Wakel Jr., Paul, E.; Vasko, Vasyl, V.; Saji, Motoyasu; Rittenberry, Jennifer; Wei, Lai; Arbogast, Daria; Collamore, Minden; Wright,. "Phase II Trial of Sorafenib in Metastatic Thyroid Cancer." J Clin Oncol. Vol. 27, no. 10. (January 2009.): 1675-1684.

Wang, Pei-Shan; Chou, Fu-Sheng; Bloomston, Mark; Vonau, Martin S.; Saji, Motoyasu; Espinosa, Allan; Pinzone, Joseph J.. "Thiazolidinediones Downregulate Wnt/beta-catenin Signaling Via Multiple Mechanisms in Breast Cancer Cells." Journal of Surgical Research. Vol. 153, no. 2. (January 2009.): 210-216.

Nadella, Kiran S.; Saji, Motoyasu; Jacob, Naduparambil K.; Pavel, Emilia; Ringel, Matthew D.; Kirschner, Lawrence S.. "Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1." EMBO Reports. Vol. 10, no. 6. (January 2009.): 599-605.

Espinosa, Allan, V.; Shinohara, Motoo; Porchia, Leonardo, M.; Chung, Yun, Jae; McCarty, Samantha; Saji, Motoyasu; Ringel, Matthew, D. "Regulator of calcineurin 1 modulates cancer cell migration in vitro." Clin Exp Metastasis. Vol. 26, no. 6. (January 2009.): 517-526.

Espinosa AV; Shinohara M; Porchia LM; Chung YJ; McCarty S; Saji M; Ringel MD. "Regulator of calcineurin 1 modulates cancer cell migration in vitro.." Clinical & Experimental Metastasis. Vol. 26, no. 6. (January 2009.): 517-.

Saji, M; Ringel, MD. "The PI3K-Akt-mTOR pathway in initiation and progression of thyroid tumors." MOLECULAR AND CELLULAR ENDOCRINOLOGY. Vol. 321, no. 1. (May 2010.): 20-28.

Lam, ET; Ringel, MD; Kloos, RT; Prior, TW; Knopp, MV; Liang, J; Sammet, S; Hall, NC; Wakely, PE; Vasko, VV; Saji, M; Snyder, PJ; Wei, L; Arbogast, D; Collamore, M; Wright, JJ; Moley, JF; Villalona-Calero, MA; Shah, MH. "Phase II Clinical Trial of Sorafenib in Metastatic Medullary Thyroid Cancer." JOURNAL OF CLINICAL ONCOLOGY. Vol. 28, no. 14. (May 2010.): 2323-2330.

Ringel,Matthew,D; Saji,Motoyasu. "Targeting invasive thyroid cancers: Defining targets and designing therapies." ENDOCRINE JOURNAL. Vol. 57, (March 2010.): S236-S236.

McCarty SK, Saji M, Zhang X, Jarjoura D, Fusco A, Vasko VV, Ringel MD. "Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion." Endocrine-Related Cancer. Vol. 17, no. 4. (January 2010.): 989-999.

Jensen K; Patel A; Larin A; Hoperia V; Saji M; Bauer A; Yim K; Hemming V; Vasko V. "Human herpes simplex viruses in benign and malignant thyroid tumours.." The Journal Of Pathology. Vol. 221, no. 2. (June 2010.): 193-.

Ringel, MD; Saji, M. "Targeting invasive thyroid cancers: Defining targets and designing therapies." ENDOCRINE JOURNAL. Vol. 57, (March 2010.): S236-S236.

Shen, RZ; Sandya, L; Li, W; Wakely, PE; Saji, M; Huang, J; Nagy, R; Farrell, T; Ringel, MD; Kloos, RT; de la Chapelle, A; He, H. "Prediction of Malignant Lesions by a Set of Four miRNAs in Thyroid Fine Needle Aspiration Specimens." MODERN PATHOLOGY. Vol. 24, (February 2011.): 105A-105A.

Shen,R,Z; Sandya,L; Li,W; Wakely,P,E; Saji,M; Huang,J; Nagy,R; Farrell,T; Ringel,M,D; Kloos,R,T; de la Chapelle,A; He,H. "Prediction of Malignant Lesions by a Set of Four miRNAs in Thyroid Fine Needle Aspiration Specimens." MODERN PATHOLOGY. Vol. 24, (February 2011.): 105A-105A.

Shen,R,Z; Sandya,L; Li,W; Wakely,P,E; Saji,M; Huang,J; Nagy,R; Farrell,T; Ringel,M,D; Kloos,R,T; de la Chapelle,A; He,H. "Prediction of Malignant Lesions by a Set of Four miRNAs in Thyroid Fine Needle Aspiration Specimens." LABORATORY INVESTIGATION. Vol. 91, (February 2011.): 105A-105A.

Bekaii-Saab, T; Phelps, MA; Li, XB; Saji, M; Goff, L; Kauh, JSW; O'Neil, BH; Balsom, S; Balint, C; Liersemann, R; Vasko, VV; Bloomston, M; Marsh, W; Doyle, LA; Ellison, G; Grever, M; Ringel, MD; Villalona-Calero, MA. "Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers." JOURNAL OF CLINICAL ONCOLOGY. Vol. 29, no. 17. (June 2011.): 2357-2363.

You,Jia; Wang,Liwen; Saji,Motoyasu; Olesik,Susan,V; Ringel,Matthew,D; Lucas,David,M; Byrd,John,C; Freitas,Michael,A. "High-sensitivity TFA-free LC-MS for profiling histones." PROTEOMICS. Vol. 11, no. 16. (August 2011.): 3326-3334.

Saji,M; Narahara,K; McCarty,S,K; Vasko,V,V; La Perle,K,M; Porter,K; Jarjoura,D; Lu,C; Cheng,S-Y; Ringel,M,D. "Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer." ONCOGENE. Vol. 30, no. 42. (October 2011.): 4307-4315.

Shen,Rulong; Liyanarachchi,Sandya; Li,Wei; Wakely,Paul,E; Saji,Motoyasu; Huang,Jie; Nagy,Rebecca; Farrell,Tisha; Ringel,Matthew,D; De la Chapelle,Albert; Kloos,Richard,T; He,Huiling. "MicroRNA Signature in Thyroid Fine Needle Aspiration Cytology Applied to "Atypia of Undetermined Significance" Cases." THYROID. Vol. 22, no. 1. (January 2012.): 9-16.

Koh,Yoon,Woo; Shah,Manisha,H; Agarwal,Kitty; McCarty,Samantha,K; Koo,Bon,Seok; Brendel,Victoria,J; Wang,Chaojie; Porter,Kyle; Jarjoura,David; Saji,Motoyasu; Ringel,Matthew,D. "Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro." ENDOCRINE-RELATED CANCER. Vol. 19, no. 1. (February 2012.): 29-38.

He,Xin; Saji,Motoyasu; Radhakrishnan,Deepa; Romigh,Todd; Ngeow,Joanne; Yu,Qi; Wang,Yu; Ringel,Matthew,D; Eng,Charis. "PTEN Lipid Phosphatase Activity and Proper Subcellular Localization Are Necessary and Sufficient for Down-Regulating AKT Phosphorylation in the Nucleus in Cowden Syndrome." JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. Vol. 97, no. 11. (November 2012.): E2179-E2187.

Ma,Yihui; McCarty,Samantha,K; Kapuriya,Naval,P; Brendel,Victoria,J; Wang,Chaojie; Zhang,Xiaoli; Jarjoura,David; Saji,Motoyasu; Chen,Ching-Shih; Ringel,Matthew,D. "Development of p21 Activated Kinase-Targeted Multikinase Inhibitors That Inhibit Thyroid Cancer Cell Migration." JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. Vol. 98, no. 8. (August 2013.): E1314-E1322.

He,Huiling; Bronisz,Agnieszka; Liyanarachchi,Sandya; Nagy,Rebecca; Li,Wei; Huang,Yungui; Akagi,Keiko; Saji,Motoyasu; Kula,Dorota; Wojcicka,Anna; Sebastian,Nikhil; Wen,Bernard; Puch,Zbigniew; Kalemba,Michal; Stachlewska,Elzbieta; Czetwertynska,Malgorzata; Dlugosinska,Joanna; Dymecka,Kinga; Ploski,Rafal; Krawczyk,Marek; Morrison,Patrick,J; Ringel,Matthew,D; Kloos,Richard,T; Jazdzewski,Krystian; Symer,David,E; Vieland,Veronica,J; Ostrowski,Michael; Jarzab,Barbara; De la Chapelle,Albert. "SRGAP1 Is a Candidate Gene for Papillary Thyroid Carcinoma Susceptibility.." journal of clinical endocrinology & metabolism. Vol. 98, no. 5. (May 2013.): E973-80.

 

Professional Activities

2010 - present Hayes Forum.
2010 - present OSU Medical Center Research Day Conference.