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Lawrence Kirschner, MD, PhD


Staff photo

1581 Dodd Dr
McCampbell Hall
Columbus, OH 43210

 

Current OSU Appointments

Professor, Endo, Diabetes & Metabolism

Physician, FGP-Endo-Diabetes & Metabolism

 

Chapters in Books

Dr Lawrence S. Kirschner. "New Strategies For The Treatment Of Adrenocortical Carcinoma." In ADRENOCORTICAL CARCINOMA. Edited by Gary Hammer and Tobias Else. -. New York, NY, US|USA: Springer, January 2010.

 

Editorial Activities

present Journal of Cellular Biochemistry
 

Journal Articles

Hsu, S, I; Cohen, D; Kirschner, L, S; Lothstein, L; Hartstein, M; Horwitz, S B. "Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells.." Molecular and cellular biology. Vol. 10, no. 7. (January 1990.): 3596-606.

Kirschner, L.S., Greenberger, L.M., Hsu, S.I.-H., Yang, C.-P.H., Cohen, D., Piekarz, R.L., Castillo, G., Han, E.K.-H., Yu, L. and Horwitz, S.B.. "Biochemical and Genetic Characterization of the Multidrug Resistance (MDR) Phenotype in Murine Macrophage-like J774.2 Cells." Biochemical Pharmacology. Vol. 43, (January 1992.): 77-87.

Kirschner, L S. "Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.." DNA and cell biology. Vol. 14, no. 1. (January 1995.): 47-59.

Kirschner, L S. "De novo generation of simple sequence during gene amplification.." Nucleic acids research. Vol. 24, no. 14. (January 1996.): 2829-34.

Yang, C, P; Kirschner, L, S; Yu, L; Horwitz, S B. "Localization of sequences that influence basal and cell type-specific activity of the murine mdr2 promoter.." Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. Vol. 7, no. 9. (January 1996.): 1227-37.

Kirschner, L, S; Stauffer, W; Krenzel, C; Duane, P G. "Management of a giant fluid-filled bulla by closed-chest thoracostomy tube drainage.." Chest. Vol. 111, no. 6. (January 1997.): 1772-4.

Vottero, A; Kirschner, L, S; Yue, W; Brodie, A; Stratakis, C A. "P450arom gene expression in peripheral blood lymphocytes: identification of a cryptic splice site for exon-1 after Epstein-Barr virus transformation.." The Journal of steroid biochemistry and molecular biology. Vol. 64, no. 5-6. (January 1998.): 245-50.

Kirschner, L, S; Taymans, S, E; Stratakis, C A. "Characterization of the adrenal gland pathology of Carney complex, and molecular genetics of the disease.." Endocrine research. Vol. 24, no. 3-4. (January 1998.): 863-4.

Stratakis, C.A., Kirschner, L.S., Carney, J.A.. "Carney complex: diagnosis and management of the complex of spotty skin pigmentation, myxomas, endocrine overactivity & schwannomas." Am. J. Med. Genet.. Vol. 80, (January 1998.): 183-185.

Stratakis, C.A., Kirschner, L.S. "Clinical and genetic analysis of bilateral adrenal diseases (micro- and macronodular disease) leading to Cushing syndrome." Horm. Metabolic Res.. Vol. 30, (January 1998.): 456-463.

Stratakis, C, A; Vottero, A; Brodie, A; Kirschner, L, S; DeAtkine, D; Lu, Q; Yue, W; Mitsiades, C, S; Flor, A, W; Chrousos, G P. "The aromatase excess syndrome is associated with feminization of both sexes and autosomal dominant transmission of aberrant P450 aromatase gene transcription.." The Journal of clinical endocrinology and metabolism. Vol. 83, no. 4. (January 1998.): 1348-57.

Stratakis, C, A; Kirschner, L, S; Taymans, S, E; Tomlinson, I, P; Marsh, D, J; Torpy, D, J; Giatzakis, C; Eccles, D, M; Theaker, J; Houlston, R, S; Blouin, J, L; Antonarakis, S, E; Basson, C, T; Eng, C; Carney, J A. "Carney complex, Peutz-Jeghers syndrome, Cowden disease, and Bannayan-Zonana syndrome share cutaneous and endocrine manifestations, but not genetic loci.." The Journal of clinical endocrinology and metabolism. Vol. 83, no. 8. (January 1998.): 2972-6.

Stratakis, C, A; Kirschner, L, S; Carney, J A. "Carney complex: diagnosis and management of the complex of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas.." American journal of medical genetics. Vol. 80, no. 2. (January 1998.): 183-5.

Stratakis, C, A; Kirschner, L S. "Clinical and genetic analysis of primary bilateral adrenal diseases (micro- and macronodular disease) leading to Cushing syndrome.." Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et metabolisme. Vol. 30, no. 6-7. (January 1998.): 456-63.

Casey, M; Mah, C; Merliss, A, D; Kirschner, L, S; Taymans, S, E; Denio, A, E; Korf, B; Irvine, A, D; Hughes, A; Carney, J, A; Stratakis, C, A; Basson, C T. "Identification of a novel genetic locus for familial cardiac myxomas and Carney complex.." Circulation. Vol. 98, no. 23. (January 1998.): 2560-6.

Taymans, S, E; Kirschner, L, S; Giatzakis, C; Stratakis, C A. "Radiation hybrid mapping of chromosomal region 2p15-p16: integration of expressed and polymorphic sequences maps at the Carney complex (CNC) and Doyne honeycomb retinal dystrophy (DHRD) loci.." Genomics. Vol. 56, no. 3. (January 1999.): 344-9.

Tarttelin, E, E; Kirschner, L, S; Bellingham, J; Baffi, J; Taymans, S, E; Gregory-Evans, K; Csaky, K; Stratakis, C, A; Gregory-Evans, C Y. "Cloning and characterization of a novel orphan G-protein-coupled receptor localized to human chromosome 2p16.." Biochemical and biophysical research communications. Vol. 260, no. 1. (January 1999.): 174-80.

Stratakis, C, A; Sarlis, N; Kirschner, L, S; Carney, J, A; Doppman, J, L; Nieman, L, K; Chrousos, G, P; Papanicolaou, D A. "Paradoxical response to dexamethasone in the diagnosis of primary pigmented nodular adrenocortical disease.." Annals of internal medicine. Vol. 131, no. 8. (January 1999.): 585-91.

Stratakis, C, A; Carney, J, A; Kirschner, L, S; Willenberg, H, S; Brauer, S; Ehrhart-Bornstein, M; Bornstein, S R. "Synaptophysin immunoreactivity in primary pigmented nodular adrenocortical disease: neuroendocrine properties of tumors associated with Carney complex.." The Journal of clinical endocrinology and metabolism. Vol. 84, no. 3. (January 1999.): 1122-8.

Kirschner, L, S; Taymans, S, E; Pack, S; Pak, E; Pike, B, L; Chandrasekharappa, S, C; Zhuang, Z; Stratakis, C A. "Genomic mapping of chromosomal region 2p15-p21 (D2S378-D2S391): integration of Genemap'98 within a framework of yeast and bacterial artificial chromosomes.." Genomics. Vol. 62, no. 1. (January 1999.): 21-33.

Kirschner, L, S; Stratakis, C A. "Large-scale preparation of sequence-ready bacterial artificial chromosome DNA using QIAGEN columns.." BioTechniques. Vol. 27, no. 1. (January 1999.): 72-4.

Kirschner, L, S; Mariash, C N. "Adipose S14 mRNA is abnormally regulated in obese subjects.." Thyroid : official journal of the American Thyroid Association. Vol. 9, no. 2. (January 1999.): 143-8.

Pack, S, D; Kirschner, L, S; Pak, E; Zhuang, Z; Carney, J, A; Stratakis, C A. "Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex).." The Journal of clinical endocrinology and metabolism. Vol. 85, no. 10. (January 2000.): 3860-5.

Stratakis, C, A; Papageorgiou, T; Premkumar, A; Pack, S; Kirschner, L, S; Taymans, S, E; Zhuang, Z; Oelkers, W, H; Carney, J A. "Ovarian lesions in Carney complex: clinical genetics and possible predisposition to malignancy.." The Journal of clinical endocrinology and metabolism. Vol. 85, no. 11. (January 2000.): 4359-66.

Stratakis, C, A; Kirschner, L S. "Isolated familial somatotropinomas: does the disease map to 11q13 or to 2p16?." The Journal of clinical endocrinology and metabolism. Vol. 85, no. 12. (January 2000.): 4920-1.

Stratakis C.A. and Kirschner L.S. "Isolated Familial Somatotropinomas: Does the Disease Map to 11q13 or to 2p16?." J Clin Endocrinol Metab. Vol. 85, (January 2000.): 4920-4924.

Watson, J.C., Stratakis, C.A., Bryant-Greenwood, P.K., Koch, C.A., Kirschner, L.S., Nguyen, T., Carney, J.A., Oldfield, E.H.. "The Neurosurgical Implications of Carney Complex." J. Neurosurg.. Vol. 92, (January 2000.): 413-418.

Watson, J, C; Stratakis, C, A; Bryant-Greenwood, P, K; Koch, C, A; Kirschner, L, S; Nguyen, T; Carney, J, A; Oldfield, E H. "Neurosurgical implications of Carney complex.." Journal of neurosurgery. Vol. 92, no. 3. (January 2000.): 413-8.

Kirschner, L, S; Stratakis, C A. "Structure of the human ubiquitin fusion gene Uba80 (RPS27a) and one of its pseudogenes.." Biochemical and biophysical research communications. Vol. 270, no. 3. (January 2000.): 1106-10.

Kirschner, L, S; Sandrini, F; Monbo, J; Lin, J, P; Carney, J, A; Stratakis, C A. "Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex.." Human molecular genetics. Vol. 9, no. 20. (January 2000.): 3037-46.

Kirschner L.S., Carney, J.A., Pack, S., Taymans, S.E., Giatzakis, C.G., Cho, Y.S., Ho-Chung, Y.S., Stratakis C.A.. "Mutations of the gene encoding the protein kinase A type I-? regulatory subunit in patients with the Carney complex." Nature Genetics. Vol. 21, (January 2000.): 88-92.

Stratakis, C, A; Kirschner, L, S; Carney, J A. "Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation.." The Journal of clinical endocrinology and metabolism. Vol. 86, no. 9. (January 2001.): 4041-6.

Sandrini, F; Farmakidis, C; Kirschner, L, S; Wu, S, M; Tullio-Pelet, A; Lyonnet, S; Metzger, D, L; Bourdony, C, J; Tiosano, D; Chan, W, Y; Stratakis, C A. "Spectrum of mutations of the AAAS gene in Allgrove syndrome: lack of mutations in six kindreds with isolated resistance to corticotropin.." The Journal of clinical endocrinology and metabolism. Vol. 86, no. 11. (January 2001.): 5433-7.

Kaltsas, Gregory, A; Kola, Blerina; Borboli, Ninetta; Morris, Damian, G; Gueorguiev, Maria; Swords, Frankie, M; Czirjak, Sandor; Kirschner, Lawrence, S; Stratakis, Constantine, A; Korbonits, Marta; Grossman, Ashley B. "Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours.." Clinical endocrinology. Vol. 57, no. 4. (January 2002.): 443-8.

Sandrini, Fabiano; Matyakhina, Ludmila; Sarlis, Nicholas, J; Kirschner, Lawrence, S; Farmakidis, Constantine; Gimm, Oliver; Stratakis, Constantine A. "Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.." Genes, chromosomes & cancer. Vol. 35, no. 2. (January 2002.): 182-92.

Sandrini, F; Kirschner, L, S; Bei, T; Farmakidis, C; Yasufuku-Takano, J; Takano, K; Prezant, T, R; Marx, S, J; Farrell, W, E; Clayton, R, N; Groussin, L; Bertherat, J; Stratakis, C A. "PRKAR1A, one of the Carney complex genes, and its locus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex.." Journal of medical genetics. Vol. 39, no. 12. (January 2002.): e78-.

Kirschner, Lawrence, S; Stratakis, Constantine A. "Protein kinase A and tumorigenicity: the example of micronodular adrenocortical hyperplasia and Carney complex.." Endocrine research. Vol. 28, no. 4. (January 2002.): 749-50.

Kirschner, Lawrence S. "Signaling pathways in adrenocortical cancer.." Annals of the New York Academy of Sciences. Vol. 968, (January 2002.): 222-39.

Kirschner, L.S., and Stratakis, C.A.. "Genetic analysis of Carney complex: current understanding and future questions." Current Opinion in Endocrinology & Diabetes. Vol. 9, (January 2002.): 244-249.

Groussin, Lionel; Kirschner, Lawrence, S; Vincent-Dejean, Caroline; Perlemoine, Karine; Jullian, Eric; Delemer, Brigitte; Zacharieva, Sabina; Pignatelli, Duarte; Carney, J Aidan; Luton, Jean Pierre; Bertagna, Xavier; Stratakis, Constantine, A; Bertherat, Jerome. "Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for." American journal of human genetics. Vol. 71, no. 6. (January 2002.): 1433-42.

Dr Lawrence S. Kirschner. "Signaling pathways in adrenocortical cancer." Ann N Y Acad Sci. Vol. 9668, (January 2002.): 222-239.

Bertherat, Jerome; Groussin, Lionel; Sandrini, Fabiano; Matyakhina, Ludmila; Bei, Thalia; Stergiopoulos, Sotirios; Papageorgiou, Theocharis; Bourdeau, Isabelle; Kirschner, Lawrence, S; Vincent-Dejean, Caroline; Perlemoine, Karine; Gicquel, Christine; Bertagna, Xavier; Stratakis, Constantine A. "Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.." Cancer research. Vol. 63, no. 17. (January 2003.): 5308-19.

Matyakhina, L; Pack, S; Kirschner, L, S; Pak, E; Mannan, P; Jaikumar, J; Taymans, S, E; Sandrini, F; Carney, J, A; Stratakis, C A. "Chromosome 2 (2p16) abnormalities in Carney complex tumours.." Journal of medical genetics. Vol. 40, no. 4. (January 2003.): 268-77.

Kirschner,L,S. "Mouse models of the Carney complex: Tools for dissecting the role of Prkar1a in tumorigenesis." JOURNAL OF INTERNAL MEDICINE. Vol. 255, no. 6. (June 2004.): 704-704.

Griffin,K,J; Kirschner,L,S; Matyakhina,L; Stergiopoulos,S,G; Robinson-White,A; Lenherr,S,M; Weinberg,F,D; Claflin,E,S; Batista,D; Bourdeau,I; Voutetakis,A; Sandrini,F; Meoli,E,M; Bauer,A,J; Cho-Chung,Y,S; Bornstein,S,R; Carney,J,A; Stratakis,C,A. "A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: Comparison with Carney complex and other PRKAR1A induced lesions." JOURNAL OF MEDICAL GENETICS. Vol. 41, no. 12. (December 2004.): 923-931.

Griffin, Kurt, J; Kirschner, Lawrence, S; Matyakhina, Ludmila; Stergiopoulos, Sotirios; Robinson-White, Audrey; Weinberg, Frank; Meoli, Elise; Bornstein, Stefan, R; Stratakis, Constantine A. "A mouse model for Carney complex.." Endocrine research. Vol. 30, no. 4. (January 2004.): 903-11.

Griffin, Kurt, J; Kirschner, Lawrence, S; Matyakhina, Ludmila; Stergiopoulos, Sotirios; Robinson-White, Audrey; Lenherr, Sara; Weinberg, Frank, D; Claflin, Edward; Meoli, Elise; Cho-Chung, Yoon, S; Stratakis, Constantine A. "Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors.." Cancer research. Vol. 64, no. 24. (January 2004.): 8811-5.

Griffin, K, J; Kirschner, L, S; Matyakhina, L; Stergiopoulos, S, G; Robinson-White, A; Lenherr, S, M; Weinberg, F, D; Claflin, E, S; Batista, D; Bourdeau, I; Voutetakis, A; Sandrini, F; Meoli, E, M; Bauer, A, J; Cho-Chung, Y, S; Bornstein, S, R; Carney, J, A; Stratakis, C A. "A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.." Journal of medical genetics. Vol. 41, no. 12. (January 2004.): 923-31.

Bourdeau, Isabelle; Antonini, Sonir, R; Lacroix, Andre; Kirschner, Lawrence, S; Matyakhina, Ludmila; Lorang, Dominique; Libutti, Steven, K; Stratakis, Constantine A. "Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators.." Oncogene. Vol. 23, no. 8. (January 2004.): 1575-85.

Kirschner, Lawrence, S; Kusewitt, Donna, F; Matyakhina, Ludmila; Towns, William H 2nd; Carney, J Aidan; Westphal, Heiner; Stratakis, Constantine A. "A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.." Cancer research. Vol. 65, no. 11. (January 2005.): 4506-14.

Kirschner,L,S; Kusewitt,D,F; Matyakhina,L; Towns,W,H; Carney,J,A; Westphal,H; Stratakis,C,A. "A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues." CANCER RESEARCH. Vol. 65, no. 11. (June 2005.): 4506-4514.

Nadella,K,S; Kirschner,L,S. "Disruption of protein kinase A regulation causes immortalization and dysregulation of D-type cyclins." CANCER RESEARCH. Vol. 65, no. 22. (November 2005.): 10307-10315.

Nadella, Kiran, S; Kirschner, Lawrence S. "Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.." Cancer research. Vol. 65, no. 22. (January 2005.): 10307-15.

Kirschner, Lawrence S. "Editorial: paradigms for adrenal cancer: think globally, act locally.." The Journal of clinical endocrinology and metabolism. Vol. 91, no. 11. (January 2006.): 4250-2.

Horvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao HP, Keil M, Heyerdahl S, Matyakhina L, Libe R, Fratticci A, Kirschner LS, Cramer K, Gaillard RC, Bertagna X, Carney JA, Bertherat J, Boss. "A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia." Nature Genetics. Vol. 38, (January 2006.): 794-800.

Kirschner, Lawrence S. "Emerging treatment strategies for adrenocortical carcinoma: a new hope.." The Journal of clinical endocrinology and metabolism. Vol. 91, no. 1. (January 2006.): 14-21.

Kirschner LS, Pavel E., Zhao W., Powell K.A., Weinstein M.. "Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.." J. Dev. Biol. (January 2007.): 273-281.

Porchia LM, Guerra M, Wang YC, Zhang Y, Espinosa AV, Shinohara M, Kulp SK, Kirschner LS, Saji M, Chen CS, Ringel MD. "A Celecoxib Derivative, Directly Targets p21 Activated Kinase." Mol Pharmacol. Vol. 72, no. 5. (January 2007.): 1124-1131.

Yin, Z. Jones, G.N., Towns, W.H., Abel, E.D., Binkley, P.F., Kirschner, L.S.. "Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.." Circulation. Vol. 117, (January 2008.): 1414-1422.

Nadella, K.S., Jones, G.N., Trimboli, A., Stratakis, C.A., Leone, G. and Kirschner, L.S.. "Targeted deletion of Prkar1a reveals a role for Protein Kinase A in Mesenchymal to Epithelial transition.." Cancer Research. Vol. 68, (January 2008.): 2671-2677.

Nadella,Kiran,S; Jones,Georgette,N; Trimboli,Anthony; Stratakis,Constantine,A; Leone,Gustavo; Kirschner,Lawrence,S. "Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition." CANCER RESEARCH. Vol. 68, no. 8. (April 2008.): 2671-2677.

Yin, Z., Williams-Simons, L., Rawaneh, L., Asa, S., and Kirschner, L.S.. "Development of a Pituitary-Specific Cre line targeted to the Pit-1 lineage." Genesis. Vol. 46, (January 2008.): 37-42.

Yin, Z., Williams-Simons, L., Parlow, A.F., Asa, S., Kirschner, L.S.. "Pituitary-specific knockout of the Carney Complex Gene Prkar1a leads to pituitary tumorigenesis." Molecular Endocrinology. Vol. 22, (January 2008.): 380-387.

Pavel,Emilia; Nadella,Kiran; Towns,William,H; Kirschner,Lawrence,S. "Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A." MOLECULAR ENDOCRINOLOGY. Vol. 22, no. 2. (February 2008.): 430-440.

Pavel, E., Nadella, K.S., Towns, W.H., Kirschner, L.S.. "Mutation of Prkar1a Causes Osteoblast Neoplasia Driven by Dysregulation of PKA." Molecular Endocrinology. Vol. 22, (January 2008.): 430-440.

Jones, G.N., Tep, C., Towns, W.H., Mihai, G., Tonks, I.D., Kay, G.F., Schmalbrock, P.M., Stemmer-Rachamimov, A., Yoon, S.O., Kirschner, L.S.. "Tissue-specific ablation of Prkar1a causes Schwannomas by suppressing NF Protein Production." Neoplasia. Vol. 10, no. 11. (November 2008.): 1213-1221.

Zhirong Yin and Lawrence S. Kirschner. "The Carney complex gene PRKAR1A plays an essential role in cardiac development and myxomagenesis." Trends in Cardiovascular Medicine. Vol. 19, no. 2. (February 2009.): 44-49.

Bertherat J, Horvath A, Groussin L, Grabar S, Boikos S, Cazabat L, Libe R, René-Corail F, Stergiopoulos S, Bourdeau I, Bei T, Clauser E, Calender A, Kirschner LS, Bertagna X, Carney JA, Stratakis CA.. "Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes.." J Clin Endocrinol Metab.. Vol. 94, no. 6. (June 2009.): 2085-2091.

Hsiao HP, Kirschner LS, Bourdeau I, Keil MF, Boikos SA, Verma S, Robinson-White AJ, Nesterova M, Lacroix A, Stratakis CA. "Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in ACTH-independent macronodular adrenal hyperplasia compared to other adrenocortical tumors." J Clin Endocrinol Metab. Vol. 94, no. 8. (August 2009.): 2930-2937.

Dr Lawrence S. Kirschner. "Use Of Mouse Models To Understand The Molecular Basis Of Tissue-Specific Tumorigenesis In The Carney Complex." Journal of Internal Medicine. Vol. 266, no. 1. (July 2009.): 60-68.

Kiran S. Nadella, Motoyasu Saji, Naduparambil K. Jacob, Emilia Pavel, Matthew D. Ringel & Lawrence S. Kirschner. "Regulation of actin function by Protein Kinase A-mediated phosphorylation of Limk1." EMBO Reports. Vol. 10, no. 6. (June 2009.): 599-605.

Sahut-Barnola I, De Joussineau C, Val P, Lambert-Langlais S, Lefrançois-Martinez AM, Pointud JC, Marceau G, Sapin V, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A.. "Mouse model for bilateral adrenal hyperplasia.." Ann Endocrinol (Paris). Vol. 70, no. 3. (June 2009.): 194-.

Kirschner LS, Yin Z, Jones GN, Mahoney E. "Mouse models of altered protein kinase A signaling." Endocrine Related Cancer. Vol. 16, no. 3. (September 2009.): 773-793.

Kirschner,L,S. "Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex." JOURNAL OF INTERNAL MEDICINE. Vol. 266, no. 1. (July 2009.): 60-68.

Tsang KM, Starost MF, Nesterova M, Boikos SA, Watkins T, Almeida MQ, Harran M, Li A, Collins MT, Cheadle C, Mertz EL, Leikin S, Kirschner LS, Robey P, Stratakis CA.. "Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Vol. 107, no. 19. (May 2010.): 8683-8688.

Lawrence S. Kirschner. "PRKAR1A and the evolution of pituitary tumors.." Molecular and Cellular Endocrinology. Vol. 326, no. 1-2. (September 2010.): 3-7.

Kirschner,Lawrence,S. "PRKAR1A and the evolution of pituitary tumors." MOLECULAR AND CELLULAR ENDOCRINOLOGY. Vol. 326, no. 1-2. (September 2010.): 3-7.

Jones GN, Manchanda PK, Pringle DR, Zhang M, Kirschner LS.. "Mouse models of endocrine tumours." Best Pract Res Clin Endocrinol Metab. Vol. 24, (January 2010.): 451-460.

Molyneux SD, Di Grappa MA, Beristain AG, McKee TD, Wai DH, Paderova J, Kashyap M, Hu P, Maiuri T, Narala SR, Stambolic V, Squire J, Penninger J, Sanchez O, Triche TJ, Wood GA, Kirschner LS, Khokha R.. "Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice.." Journal of Clinical Investigation. (August 2010.): -.

Sahut-Barnola I, de Joussineau C, Val P, Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC, Marceau G, Sapin V, Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A.. "Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.." PLoS Genetics. Vol. 10, no. 6. (June 2010.): -.

Jones GN, Pringle DR, Yin Z, Carlton MM, Powell KA, Weinstein MB, Toribio RE, La Perle KM, Kirschner LS.. "Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification.." Molecular Endocrinology. Vol. 24, no. 8. (August 2010.): 1559-1568.

Yin Z, Pringle DR, Jones GN, Kelly KM, Kirschner LS. "Differential Role of PKA Catalytic Subunits in Mediating Phenotypes Caused by Knockout of the Carney Complex Gene Prkar1a." Molecular Endocrinology. (January 2011.): -.

Song WJ, Seshadri M, Ashraf U, Mdluli T, Mondal P, Keil M, Azevedo M, Kirschner LS, Stratakis CA, Hussain MA. "Snapin mediates incretin action and augments glucose-dependent insulin secretion.." Cell Metabolism. no. 13. (January 2011.): 308-319.