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Razvan Arsenescu, MD, PhD


395 W 12th Ave
Columbus, OH 43210

Email: arsenescu.1@osu.edu

 

Current OSU Appointments

Associate Professor, Gastro, Hepatology & Nutrition

Physician, FGP-Gastro-Hepatology & Nutr'n

 

Clinical Interest

Gastroenterology, Immunopathology

Certifications

2000 - present Board Certified Internal Medicine: American Board of Internal Medicine (ABIM)
2003 - present Board Certified Gastroenterology: American Board of Internal Medicine (ABIM)
 

Degrees

1994 M.D., Targu-Mures General Hospital

2010 Ph.D., University of Kentucky Medical Center

 

Journal Articles

Weinstock,J,V; Blum,A; Metwali,A; Elliott,D; Bunnett,N; Arsenescu,R. "Substance P regulates Th1-type colitis in IL-10 knockout mice." JOURNAL OF IMMUNOLOGY. Vol. 171, no. 7. (October 2003.): 3762-3767.

Weinstock,J,V; Blum,A; Metwali,A; Elliott,D; Arsenescu,R. "IL-18 and IL-12 signal through the NF-kappa B pathway to induce NK-1R expression on T cells." JOURNAL OF IMMUNOLOGY. Vol. 170, no. 10. (May 2003.): 5003-5007.

Mardini,H,E; Gregory,K,J; Nasser,M; Selby,L; Arsenescu,R; Winter,T,A; de Villiers,W,JS. "Gastroduodenal Crohn's disease is associated with NOD2/CARD15 gene polymorphisms, particularly L1007P homozygosity." DIGESTIVE DISEASES AND SCIENCES. Vol. 50, no. 12. (December 2005.): 2316-2322.

Arsenescu,R; Blum,A,M; Metwali,A; Elliott,D,E; Weinstock,J,V. "IL-12 induction of mRNA encoding substance P in murine macrophages from the spleen and sites of inflammation." JOURNAL OF IMMUNOLOGY. Vol. 174, no. 7. (April 2005.): 3906-3911.

Cox,Thadis; Koch,Alvaro,Gonzalez; Bosch,Antonio; Arsenescu,Razvan; Winter,Trevor; Tsai,Chung-Jyi; Nickl,Nicholas; De Villiers,Willem; Pena,Luis. "Prospective study comparing esophageal capsule endoscopy (ECE) vs. upper endoscopy (EGD) in the detection and grading of esophageal varices." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 101, no. 9. (September 2006.): S176-S177.

Grigorian,Alla; Mardini,Houssam; Arsenescu,Razvan; Winter,Trevor; De Villiers,Willem. "Predictors of short and long term response to azathioprine in Crohn's disease." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 102, (September 2007.): S476-S477.

Grigorian,Alla; Mardini,Houssam,E; Selby,Lisbeth,A; Arsenescu,Razvan,I; Winter,Trevor,A; de villiers,Willem,J. "Predictors of long term response to infliximab beyond the first year." GASTROENTEROLOGY. Vol. 132, no. 4. (April 2007.): A185-A185.

Arsenescu,Razvan,I; Zhong,Jian; Narsimhan,Meena; Wroblewski,Joanne; Arsenescu,Violeta; Eckhardt,Eric; De Villiers,Willem. "Adiponectin and the plant agonist osmotin promote IL-10 production in a murine model of colitis." GASTROENTEROLOGY. Vol. 132, no. 4. (April 2007.): A12-A12.

Mardini,Houssam; Arsenescu,Razvan; Winter,Trevor; De Villiers,Willem. "Clinical predictors of elevated C-reactive protein (CRP) among patients with active inflammatory bowel disease." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 102, (September 2007.): S476-S476.

Arsenescu,R; Bruno,M,EC; Rogier,E,W; Stefka,A,T; McMahan,A,E; WRIGHT,T,B; Nasser,M,S; de Villiers,W,JS; Kaetzel,C,S. "Signature biomarkers in Crohn's disease: toward a molecular classification." MUCOSAL IMMUNOLOGY. Vol. 1, no. 5. (September 2008.): 399-411.

Mardini,Houssam,E; Bryson,Ben; Flomenhoft,Deborah,R; Arsenescu,Razvan,I; de villiers,Willem,J. "Post marketing clinical experience with adalimumab in Crohn's disease." GASTROENTEROLOGY. Vol. 134, no. 4. (April 2008.): A473-A473.

Kaetzel,Charlotte,S; Bruno,Maria,EC; Stefka,Andrew; McMahan,Adam; Arsenescu,Razvan. "Dysregulated expression patterns of pro- and anti-inflammatory biomarkers in the intestinal mucosa define phenotypic subsets of Crohn's Disease." FASEB JOURNAL. Vol. 22, (April 2008.): -.

Arsenescu,Violeta; Zhong,Jian; Arsenescu,Razvan,I; de villiers,Willem,J; Swanson,Hollie,I. "Aryl hydrocarbon receptor pathway modulates the activity of colitis." GASTROENTEROLOGY. Vol. 134, no. 4. (April 2008.): A44-A44.

Arsenescu,Razvan,I; Bruno,Maria; de villiers,Willem,J; Kaetzel,Charlotte. "Dysregulation of the polymeric immunoglobulin receptor in Crohn's disease." GASTROENTEROLOGY. Vol. 134, no. 4. (April 2008.): A397-A398.

Arsenescu,Razvan,I; Arsenescu,Violent; Mardini,Houssam,E; Flomenhoft,Deborah,R; de villiers,Willem,J. "Crohn's disease a state of adiponectin resistance." GASTROENTEROLOGY. Vol. 134, no. 4. (April 2008.): A431-A431.

Arsenescu,Violeta; Arsenescu,Razvan,I; King,Victoria; Swanson,Hollie; Cassis,Lisa,A. "Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis." ENVIRONMENTAL HEALTH PERSPECTIVES. Vol. 116, no. 6. (June 2008.): 761-768.

Arsenescu,Razvan,I; Arsenescu,Violeta; Zhong,Jian; de villiers,Willem,J; Nasser,Munira. "Linking Metabolism and Colitis: the Macrophage Connection." GASTROENTEROLOGY. Vol. 136, no. 5. (May 2009.): A83-A83.

Arsenescu,Razvan,I; Arsenescu,Violeta; Zhong,Jian; de villiers,Willem,J; Nasser,Munira. "Exposure to Environmental Toxin TCDD Increases Severity of Colitis." GASTROENTEROLOGY. Vol. 136, no. 5. (May 2009.): A731-A731.

Kelly,Ciaran,P; Green,Peter,H; Murray,Joseph,A; Dimarino,Anthony,J; Arsenescu,Razvan,I; Colatrella,Anthony,M; Leffler,Daniel,A; Alexander,Thomas,J; Jacobstein,Douglas; Leon,Francisco; Jiang,John; Fedorak,Richard,N. "Safety, Tolerability and Effects On Intestinal Permeability of Larazotide Acetate in Celiac Disease: Results of a Phase IIB 6-Week Gluten-Challenge Clinical Trial." GASTROENTEROLOGY. Vol. 136, no. 5. (May 2009.): A474-A474.

Mardini,Houssam,E; Grigorian,Alla; Flomenhoft,Deborah,R; Arsenescu,Razvan,I; de villiers,Willem,J. "The Utility of Urine Histoplasma Antigen As a Screening Test Before and During Anti-TNF-alpha Therapy in Inflammatory Bowel Disease Patients in Endemic Area." GASTROENTEROLOGY. Vol. 136, no. 5. (May 2009.): A193-A194.

Eckhardt,Erik,RM; Witta,Jassir; Zhong,Jian; Arsenescu,Razvan; Arsenescu,Violeta; Wang,Yu; Ghoshal,Sarbani; de Beer,Marcielle,C; de Beer,Frederick,C; de Villiers,Willem,JS. "Intestinal Epithelial Serum Amyloid A Modulates Bacterial Growth In Vitro and Pro-Inflammatory Responses in Mouse Experimental Colitis." BMC GASTROENTEROLOGY. Vol. 10, (November 2010.): 133-.

Bishu,Shrinivas; Hamiduzzaman,Saba; Salas,Edgar; Dawkins,Adrian; Patel,Viral; Arsenescu,Violetta; De Villiers,Willem; Arsenescu,Razvan. "The Clinical Phenotype of Obese and Overweight Crohn's Disease Patients." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 105, (October 2010.): S460-S461.

Rogier,Eric; Kaetzel,Charlotte,S; Arsenescu,Violeta; Arsenescu,Razvan. "Adiponection Priming of Oral and Intestinal Epithelial Cells Modulates the Cytokine Response to TLR and TNF Signaling." GASTROENTEROLOGY. Vol. 140, no. 5. (May 2011.): S636-S637.

Arsenescu,Razvan; Arsenescu,Violeta; Zhong,Jian; Nasser,Munira; Melinte,Razvan; Dingle,R,WCameron; Swanson,Hollie; de villiers,Willem,J. "Role of the Xenobiotic Receptor in Inflammatory Bowel Disease." INFLAMMATORY BOWEL DISEASES. Vol. 17, no. 5. (May 2011.): 1149-1162.

Arsenescu,Razvan; Arsenescu,Violeta; Rogier,Eric; De Villiers,Willem; Novak,Karen; Novak,Michael,J; Kaetzel,Charlotte,S. "Coordinated Immune Responses in Oral and Intestinal Mucosa." GASTROENTEROLOGY. Vol. 140, no. 5. (May 2011.): S499-S499.

Arsenescu,Razvan; Arsenescu,Violeta; de Villiers,Willem,JS. "TNF-alpha and the Development of the Neonatal Immune System: Implications for Inhibitor Use in Pregnancy." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 106, no. 4. (April 2011.): 559-562.

Schrinivas,Bishu; Arsenescu,Violeta; Witta,Jassir; De Villiers,Willem; Arsenescu,Razvan. "Impact of Obesity on Ulcerative Colitis Phenotype." GASTROENTEROLOGY. Vol. 140, no. 5. (May 2011.): S193-S193.

Bishu,Shrinivas; Salas,Edgar; Hamiduzzaman,Saba; Dawkins,Adrian; Arsenescu,Violetta; de Villiers,W; Arsenescu,Razvan. "The Impact of Obesity on the Phenotype of Ulcerative Colitis." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 106, (October 2011.): S446-S447.

Bishu,Shrinivas; Ditah,Ivo; Dawkins,Adrian; Hamiduzzaman,Saba; Salas,Edgar; Arsenescu,Violetta; de Villiers,W; Arsenescu,Razvan. "Computed Tomography Measured Parameters of Obesity and Crohn's Disease Phenotype." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 106, (October 2011.): S482-S483.

Arsenescu,Violeta; Narasimhan,Meena,L; Halide,Tuna; Bressan,Ray,A; Barisione,Chiara; Cohen,Donald,A; de Villiers,Willem,JS; Arsenescu,Razvan. "Adiponectin and Plant-Derived Mammalian Adiponectin Homolog Exert a Protective Effect in Murine Colitis." DIGESTIVE DISEASES AND SCIENCES. Vol. 56, no. 10. (October 2011.): 2818-2832.

Bishu,Shrinivas; Arsenescu,Violeta; Lee,Eun,Y; Vargas,H,David; de Villiers,Willem,JS; Arsenescu,Razvan. "Autoimmune enteropathy with a CD8(+) CD7(-) T-cell small bowel intraepithelial lymphocytosis: case report and literature review." BMC GASTROENTEROLOGY. Vol. 11, (November 2011.): 131-.

Arsenescu,Violeta; Arsenescu,Razvan; Parulkar,Madhura; Karounos,Michael; Zhang,Xuan; Baker,Nicki; Cassis,Lisa,A. "Polychlorinated biphenyl 77 augments angiotensin II-induced atherosclerosis and abdominal aortic aneurysms in male apolipoprotein E deficient mice." TOXICOLOGY AND APPLIED PHARMACOLOGY. Vol. 257, no. 1. (November 2011.): 148-154.

Sideri,Aristea; Stavrakis,Dimitris; Arsenescu,Razvan; Bakirtzi,Kyriaki; Karagiannidis,Iordanis; Pothoulakis,Charalabos. "Increased SP Proinflammatory Responses in Human Mesenteric Preadipocytes Isolated From Ulcerative Colitis Patients." GASTROENTEROLOGY. Vol. 142, no. 5. (May 2012.): S594-S595.

Arsenescu,Violeta; Marti,Francesc; Arsenescu,Razvan. "High Fat Diet Promotes Chronic Inflammation in DSS Murine Model of IBD." GASTROENTEROLOGY. Vol. 142, no. 5. (May 2012.): S908-S909.

Kelly,C,P; Green,P,HR; Murray,J,A; DiMarino,A; Colatrella,A; Leffler,D,A; Alexander,T; Arsenescu,R; Leon,F; Jiang,J,G; Arterburn,L,A; Paterson,B,M; Fedorak,R,N. "Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study." ALIMENTARY PHARMACOLOGY & THERAPEUTICS. Vol. 37, no. 2. (January 2013.): 252-262.

Sideri,Aristea; Bakirtzi,Kyriaki; Arsenescu,Razvan; Fleshner,Phillip; Shih,David,Q; Pothoulakis,Charalabos; Karagiannidis,Iordanis. "Preadipocyte-Specific Effects on Human Colonocyte Proinflammatory Responses Are Obesity and IBD-Dependent." GASTROENTEROLOGY. Vol. 144, no. 5. (May 2013.): S820-S821.

Sideri,Aristea; Bakirtzi,Kyriaki; Arsenescu,Razvan; Fleshner,Phillip; Shih,David,Q; Karagiannidis,Iordanis; Pothoulakis,Charalabos. "Effects of Substance P on Pro and Anti-Inflammatory Responses of Human Mesenteric Preadipocytes Isolated From IBD Patients." GASTROENTEROLOGY. Vol. 144, no. 5. (May 2013.): S100-S100.

Ghigliotti,Giorgio; Barisione,Chiara; Garibaldi,Silvano; Fabbi,Patrizia; Brunelli,Claudio; Spallarossa,Paolo; Altieri,Paola; Rosa,Gianmarco; Spinella,Giovanni; Palombo,Domenico; Arsenescu,Razvan; Arsenescu,Violeta. "Adipose Tissue Immune Response: Novel Triggers and Consequences for Chronic Inflammatory Conditions." INFLAMMATION. Vol. 37, no. 4. (August 2014.): 1337-1353.

Ali,Mohamed,M; Newsom,David,L; Gonzalez,Juan,F; Sabag-Daigle,Anice; Stahl,Christopher; Steidley,Brandi; Dubena,Judith; Dyszel,Jessica,L; Smith,Jenee,N; Dieye,Yakhya; Arsenescu,Razvan; Boyaka,Prosper,N; Krakowka,Steven; Romeo,Tony; Behrman,Edward,J; White,Peter; Ahmer,Brian,MM. "Fructose-Asparagine Is a Primary Nutrient during Growth of Salmonella in the Inflamed Intestine." PLOS PATHOGENS. Vol. 10, no. 6. (June 2014.): e1004209-.