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James Hanje, MD


395 W 12th Avenue
Columbus, OH 43210

Phone: (614) 293-6255

Email: hanje.1@osu.edu

 

Current OSU Appointments

Assistant Professor-Clinical, Gastro, Hepatology & Nutrition

Physician, FGP-Gastro-Hepatology & Nutr'n

 

Clinical Interest

Gastroenterology, Internal Medicine, Transplant Hepatology

Biographical

In my time at OSUWMC, my contribution in the area of curriculum development has focused on building the institutional infrastructure necessary to support a Hepatology and Liver Transplant program. This has involved a multi-faceted approach.



In the area of excellence in teaching and mentoring, my contributions are reflected by the growth and acceptance of Hepatology as a preeminent area of future practice amongst the students, residents and fellows trained at this institution. Direct examples of honors and awards are detailed in the curriculum development narrative in my dossier.



In the area of excellence in scholarship, I have led innovations in areas such quality initiatives, protocol development, collaboration with local, regional and national experts on research projects and systems-based workflow solutions. All of these activities have contributed to a growth and change in the discipline of Hepatology and have made The Ohio State University Wexner Medical Center (OSUWMC) a regional Center of Excellence for care of these patients.



In the area of excellence in clinical practice and patient care, I have led the building of institutional infrastructure necessary to support a liver program. This core commitment to superlative care of the very sickest and most complex patients is why increasing numbers of referring physicians from throughout the state and region now send their patients and family members to this institution for Hepatology-related care. The number of outpatient Hepatology and Liver Transplant referrals have increased during my time here. The creation of a dedicated Hepatology consult service and the evolution of the inpatient service to one of strictly liver patients reflect this change in institutional culture and outside recognition. Outcomes in Liver Transplant patients have improved significantly as well, reflecting an overall commitment to both growth and high quality, patient-centered care. I have led the growth and maturation of the Hepatology team, including the hiring of board-certified Transplant Hepatologists and sub-specialty trained physician extenders, nurses and organ-specific transplant coordinators.



Since assuming leadership as Director of Hepatology, I have committed to building the institutional infrastructure necessary to become a center of excellence in Hepatology and Transplant Hepatology. I have led the growth of this new and unique area of practice at Ohio State. Promotion within the Clinical Excellence pathway requires demonstrable excellence in the Scholarship of Practice, and I feel my contributions have and always will reflect this underlying principle.

Certifications

- 2003 Internal Medicine: American Board of Internal Medicine
- 2007 Gastroenterology & Hepatology: American Board of Internal Medicine
- 2008 Transplant Hepatology: American Board of Internal Medicine
 

Chapters in Books

Hanje AJ, Michaels AJ, Lee WM. "N-Acetylcysteine for all non-acetaminophen acute liver failure.." In Controversies in Hepatology: The Experts Analyze Both Sides.. Edited by Donald Jensen, MD. -. Thorofare, NJ, US|USA: PNS & WSS Incorporated dba SLACK Incorporated, Delaware Corporation, January 2010.

 

Clinical Services

08/01/2008 Hepatology Consult Service (OSU Medical Center)
08/01/2008 Hepatology Inpatient Service (OSU Medical Center)
08/01/2008 Hepatology Outpatient Clinic (OSU Medical Center)

Conferences

Li, Feng; Lee, Bryan; Lilly, Scott; Hanje, A. James. "Post-transplant Cardiac Events Among Patients Receiving Orthotopic Liver Transplant Associated With Positive Stress Test." ACG 2014 Annual Scientific Meeting and Postgraduate Course. .

Jasem, Jager; Park, Jean R.; Lockhart, Gabriel C.; Hanje, A. James. "Iatrogenic Superior Mesenteric Arterio-venous Fistula as an Unusual Cause of Refractory Ascites: A Case Report." ACG 2014 Annual Scientific Meeting and Postgraduate Course. .

Savona, Salvatore; Rosetti, Arnold; Arnold, Christina; Hanje, A. James. "Massive Lower Gastrointestinal Bleed With AL Amyloidosis." ACG 2014 Annual Scientific Meeting and Postgraduate Course. .

Esber, Chris; Brook, Loren; Hanje, A. James. "Outcomes in Orthotopic Liver Transplantation; Rotational Thromboelastrography (ROTEM) versus Standard of Care: a Retrospective Study." AASLD 2014 Annual Meeting. .

 

Degrees

2000 M.D., The Ohio State University

 

Honors

2009 - 2010 Faculty Inpatient Teacher of the Year 2009-2010.
2009 - 2010 Excellence in Teaching 2009-2010.
2010 - 2011 Teacher of the Year 2010-2011.
2010 - 2011 Faculty Inpatient Teacher of the Year 2010-2011.
2010 - 2011 Excellence in Teaching 2010-2011.
 

Journal Articles

Hanje AJ; Shamp JL; Thomas FB; Meis GM. "Thalidomide-induced severe hepatotoxicity.." Pharmacotherapy. Vol. 26, no. 7. (July 2006.): 1018-.

Hanje AJ; Pell LJ; Votolato NA; Frankel WL; Kirkpatrick RB. "Case report: fulminant hepatic failure involving duloxetine hydrochloride.." Clinical Gastroenterology And Hepatology: The Official Clinical Practice Journal Of The American Gastroenterological Association. Vol. 4, no. 7. (July 2006.): 912-.

Hanje AJ; Fortune B; Song M; Hill D; McClain C. "The use of selected nutrition supplements and complementary and alternative medicine in liver disease.." Nutrition In Clinical Practice: Official Publication Of The American Society For Parenteral And Enteral Nutrition. Vol. 21, no. 3. (June 2006.): 255-.

Hanje AJ; Patel T. "Preoperative evaluation of patients with liver disease.." Nature Clinical Practice. Gastroenterology & Hepatology. Vol. 4, no. 5. (May 2007.): 266-.

Hanje AJ; Chalasani N. "How common is chronic liver disease from acute drug-induced liver injury?." Gastroenterology. Vol. 132, no. 5. (May 2007.): 2067-.

Hanje,A,James; Patel,Tushar. "Authors' response to "How to dispel myths in the treatment of hepatic encephalopathy?"." NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY. Vol. 4, no. 10. (October 2007.): E2-E2.

Hanje,James; Patel,Tushar. "Preoperative evaluation of patients with liver disease." NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY. Vol. 4, no. 5. (May 2007.): 266-276.

Hanje,A,James; Patel,Tushar. "Preoperative evaluation of patients with liver disease (vol 4, pg 266, 2007)." NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY. Vol. 4, no. 7. (July 2007.): 409-409.

Hanje AJ; Yao FY. "Current approach to down-staging of hepatocellular carcinoma prior to liver transplantation.." Current Opinion In Organ Transplantation. Vol. 13, no. 3. (June 2008.): 234-.

McIntire,Jennifer; Hanje,A,James; Thomas,Fred; South,Christopher. "Endoscopic and Histologic Evaluation of Henoch-Schonlein Purpura in an Adult Apropos a Case." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 105, (October 2010.): S240-S240.

Sklaw,Brett; Hanje,A; Azzouz,Maher. "A 33 Year-Old Male with a Type IIIA Choledochocele." AMERICAN JOURNAL OF GASTROENTEROLOGY. Vol. 106, (October 2011.): S210-S211.

Li,Feng; Zhang,Johnathan; Abdel-Rasoul,Mahmoud; Hanje,Adam,J; Kirkpatrick,Robert,B. "A community-based hepatitis B screening program in the Asian community of central Ohio." HEPATOLOGY. Vol. 56, (October 2012.): 636A-637A.

Li,Feng; Hutton,David,W; Abdel-Rasoul,Mahmoud; Kirkpatrick,Robert,B; Hanje,Adam,J. "A cost effectiveness analysis of a community-based HBV screening and treatment program conducted among an Asian population in Central Ohio." HEPATOLOGY. Vol. 56, (October 2012.): 353A-353A.

Rock,J,B; Yearsley,M,M; Hanje,A,J; Frankel,W,L. "Collagen Immunohistochemical Stains in the Liver Are Useful in Differentiating Capsular from Septal Fibrosis." LABORATORY INVESTIGATION. Vol. 92, (February 2012.): 422A-423A.

Rock,J,B; Yearsley,M,M; Hanje,A,J; Frankel,W,L. "Collagen Immunohistochemical Stains in the Liver Are Useful in Differentiating Capsular from Septal Fibrosis." MODERN PATHOLOGY. Vol. 25, (February 2012.): 422A-423A.

Fix,O,K; Liou,I; Karvellas,C; Ganger,D; Forde,K,A; Subramanian,R; Boylan,A; Hanje,J; Stravitz,R,T; Lee,W,M. "DEVELOPMENT AND PILOT OF A CHECKLIST FOR MANAGEMENT OF ACUTE LIVER FAILURE IN THE INTENSIVE CARE UNIT." JOURNAL OF HEPATOLOGY. Vol. 58, (April 2013.): S410-S410.

McNally,Megan,E; Martinez,Antonio; Khabiri,Hooman; Guy,Gregory; Michaels,Anthony,J; Hanje,James; Kirkpatrick,Robert; Bloomston,Mark; Schmidt,Carl,R. "Inflammatory Markers are Associated with Outcome in Patients with Unresectable Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization." ANNALS OF SURGICAL ONCOLOGY. Vol. 20, no. 3. (March 2013.): 923-928.

Henry,Jon,C; Malhotra,Lavina; Khabiri,Hooman; Guy,Gregory; Michaels,Anthony; Hanje,James; Azevedo,Marcela; Bloomston,Mark; Schmidt,Carl,R. "Best radiological response to trans-arterial chemoembolization for hepatocellular carcinoma does not imply better outcomes." HPB. Vol. 15, no. 3. (March 2013.): 196-202.

Fix,Oren,K; Liou,Iris; Karvellas,Constantine; Ganger,Daniel; Forde,Kimberly,A; Subramanian,Ram,M; Boylan,Alice,M; Hanje,A,James; Stravitz,R,Todd; Lee,William,M. "Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit." GASTROENTEROLOGY. Vol. 144, no. 5. (May 2013.): S956-S956.

 

Presentations

"Treatment of Hepatitis C." Presented at Internal Medicine Grand Rounds, Columbus, OH. (June 2003)

"Complications of Cirrhosis." Presented at Internal Medicine Lecture Series, Columbus, OH. (August 2004)

"Current Treatment Options for Chronic Hepatitis C." Presented at Veterans Administration Lecture Series, Chillicothe, OH. (January 2005)

"Update on Treatment Options for Chronic Hepatitis C." Presented at Veterans Administration Lecture Series, Chillicothe, OH. (January 2006)

"Upper Gastrointestinal Bleeding." Presented at Veterans Administration Lecture Series, Chillicothe, OH. (January 2007)

"Portal Hypertension." Presented at Internal Medicine Lecture Series, Columbus, OH. (September 2008)

"Expanded Criteria for Liver Transplantation of Hepatocellular Carcinoma." Presented at Gastroenterology Grand Rounds, San Francisco. (February 2008)

"Outcome Following Salvage Liver Transplant for Recurrent Hepatocellular Carcinoma after Resection: Analysis of the OPTN Database.." Presented at International Liver Cancer Association Annual Meeting, Chicago. (September 2008)

"Managing Complications of Cirrhosis." Presented at Good Samaritan Hospital Grand Rounds, Zanesville. (December 2008)

"Outcome Following Salvage Liver Transplant for Recurrent Hepatocellular Carcinoma after Resection: Analysis of the OPTN Database." Presented at American Association for the Study of Liver Diseases Annual Meeting, San Francisco. (October 2008)

"Fulminant Hepatic Failure." Presented at Internal Medicine Lecture Series, Columbus, OH. (January 2009)

"Portal Hypertensive Bleeding." Presented at MedNet, Columbus, OH. (April 2009)

"Epidemiology of Hepatocellular Carcinoma." Presented at James Cancer Symposium on Liver Cancer 2009, Columbus. (April 2009)

"Hepatitis B and HBIG." Presented at Pharmacy Grand Rounds, Columbus, OH. (May 2010)

"Multidisciplinary Approach to Management of Acute Liver Failure." Presented at MATCH conference 2010, . (September 2010)

"Portal Hypertensive Bleeding." Presented at ICU Lecture Series, Columbus, OH. (February 2010)

"Mangement of Upper GI Bleeding." Presented at Internal Medicine Lecture Series, . (July 2010)

"Portal Hypertensive Bleeding." Presented at Internal Medicine Lecture Series, Columbus, OH. (July 2010)

"CTC Transplant Symposium 2011." Presented at CTC Transplant Symposium 2011, . (June 2011)

"Evidenced-Based literature review of SBP." Presented at Internal Medicine Lecture Series, . (April 2011)

"Early Use of TIPS in Cirrhosis and Variceal Bleeding." Presented at Internal Medicine Journal Club, . (April 2011)

"Complications of Cirrhosis: Ascites, SBP and HRS." Presented at Internal Medicine Lecture Series, . (September 2011)

"Portal Hypertension: Ascites, Hepatorenal Syndrome and TIPS." Presented at Internal Medicine Lecture Series, . (February 2011)

"Complications of Cirrhosis: Portal Hypertensive Bleeding." Presented at Internal Medicine Lecture Series, . (August 2011)

"Management of Cirrhotic Patient from a Primary Care Perspective." Presented at Licking Memorial Hospital Grand Rounds, . (March 2012)

"Liver Transplantation." Presented at Ohio State University Comprehensive Transplant Center Symposium, . (October 2012)

"Approach to Acute Liver Failure 2012." Presented at Mount Carmel Grand Rounds, . (June 2012)

"Management of the Cirrhotic Patient from a Primary Care Perspective." Upper Sandusky, OH. (January 2012)

"Acute Liver Failure." Presented at Pulmonary/Critical Care Lecture Series, . (January 2012)

"Evaluating the High Risk Liver Transplant Patient." Presented at Ohio State University Comprehensive Transplant Center Symposium, . (October 2013)

"Treatment of HCV - Update 20123." Presented at Ohio Gastroenterology Group Journal Club, . (December 2013)

"Acute Liver Failure 2013." Presented at 23rd Annual Dayton Gastroenterology Symposium, . (November 2013)

"Update on Acute Liver Failure 2014." Presented at OSUWMC Division of GHN DDW Update 2014, . (June 2014)

 

Professional Activities

2008 - present Asian Hepatitis B Free clinic. Columbus, OH.