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Fanyin Meng, MD, PhD
Assistant Professor
Room 514 Medical Research Facility
420 W. 12th Avenue
Columbus, OH 43210
(614) 688-5767
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Education
- MD, Second Military Medical University, Shanghai, China,1985
- Ph.D, Trauma and Burn Institute, Second Military Medical University, Shanghai, China, 1992
- M.S, Software Engineering, University of Texas at Dallas, Richardson, Texas, 2003
Research Interests
- Angiogenesis in Liver Carcinogenesis
- Gene Therapy of Liver Injury and Neoplasm
- Microarray Bioinformatics in Liver Diseases
Professional Background
- University of Texas at Dallas / Research Scientist Associate, 2001-2003.
- Scott & White Memorial Hospital, Texas A&M University Health Science Center / Research Scientist, 2004-2005.
- Texas A&M University College of Medicine / Instructor, 2005-2006.
- Texas A&M University College of Medicine / Assistant Professor (Non-Tenure Track), 2006-2007.
- Ohio State University Medical Center / Assistant professor (Tenure Track), 2007-present.
Representative Peer Review Publications
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulated expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007 Aug;133(2):647-58.
Meng F, Wehbe-Janek H, Henson R, Smith H, Patel T. Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene. 2007 Jul 9; doi: 10.1038/sj.onc.1210648
Meng F, Henson R, Patel T. Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. Am J Physiol Cell Physiol. 2007 Aug;293(2):C749-60.
Meng F, Henson R, Wehbe H, Patel T. The microRNA let 7A modulates Interleukin-6 dependent Stat-3 survival signaling in malignant human cholangiocytes. J Biol Chem. 2007 Mar 16;282(11):8256-64.
Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T.Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 2006 Jun;130(7):2113-29.
Meng F, Yamagiwa Y, Ueno Y, Patel T. Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes. J Hepatol. 2006 Jun;44(6):1055-65.
Meng F, Yamagiwa Y, Taffetani S, Han J, Patel T. IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway. Am J Physiol Cell Physiol. 2005 Oct;289(4):C971-81.
Meng F, D'Mello SR. NF-kappaB stimulates Akt phosphorylation and gene expression by distinct signaling mechanisms. Biochim Biophys Acta. 2003 Oct 20;1630(1):35-40.
Meng F, Huang XP, Zhang C, Zajdel RW, Foster D, Dawson N, Lemanski SL, Zawieja D, Dube DK, Lemanski LF. Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development. Tissue Cell. 2003 Apr;35(2):133-42.
Meng F, Liu L, Chin PC, D'Mello SR. Akt is a downstream target of NF-kappa B. J Biol Chem. 2002 Aug 16;277(33):29674-80.
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