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Sofowora, Gbemiga MD


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473 W 12th Avenue, Suite 200
Columbus, OH 43210-1267

Phone: (614) 293-4967

Email: sofowora.1@osu.edu

 

Current OSU Appointments

Appointment, OSU Physicians

Assistant Professor-Clinical, Cardiovascular Medicine

 

Abstracts and Short Entries

GG Sofowora , AO Adigun, AT Ajayi, AA Ajayi. "Evidence of Synergism between ACE-inhibitor and Alpha-1 Adrenergic Blockade During Forearm Isometric Exercise in Normal Man." [Abstract]. Nigerian Cardiac Society. (1995) [Peer Reviewed] (Published)

AA Ajayi, MO Balogun, GG Sofowora . "Concurrent Alpha-Blockade and ACE-Inhibition in the Treatment of Congestive Heart Failure." [Abstract]. Nigerian Cardiac Society. (1996) [Peer Reviewed] (Published)

GG Sofowora , I Singh, CM Stein, HB He, AJJ Wood. "Adrenergic Responses in Post-menopausal Women: No Evidence of Modulation By Estrogen." [Abstract]. Clinical Pharmacology and Therapeutics. (February 1999) [Peer Reviewed] (Published)

GG Sofowora , EF Choo, G Mayo, GR Wilkinson. "In vivo Inhibition of CYP1A2 Activity by Oltipraz" [Abstract]. Clinical Pharmacology and Therapeutics. (February 2000) [Peer Reviewed] (Published)

HG Xie, CM Stein, RB Kim, GG Sofowora , V Dishy, ZS Xiao, N He, H Zhou, AJJ Wood. "Frequency of Endothelial Nitric Oxide Synthase Glu 298-Asp Polymorphism Varies Among African-Americans (AA), Caucasians (CA), and Chinese." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2000) [Peer Reviewed] (Published)

HG Xie, RB Kim, V Dishy, GG Sofowora , ZS Xiao, N Ho, HH Zhou, AJJ Wood, CM Stein. "Ethnic Differences in Beta-1 Adrenoceptor (BAR-1) Polymorphism (Gly 389 - Arg) Frequency in African-Americans (AA), Caucasians (CA), and Chinese." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2000) [Peer Reviewed] (Published)

V Dishy, GG Sofowora , M Kandcer, F Zhan, AJJ Wood, CM Stein. "The Effect of Sildenafil Citrate on nitric Oxide-Mediated Responses." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2000) [Peer Reviewed] (Published)

V Dishy, GG Sofowora , HG Xie, D Byrne, RB Kim, CM Stein, AJ Wood. "Beta-222 Adrenergic Receptor Polymorphism Affects Agonist Mediated Vasodilatation and Desensitization in Vivo." [Abstract]. Circulation. (October 2000) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, D Roden, AJJ Wood, CM Stein. "Effect of Sildenafil on QT Interval in Healthy Men" [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, H Imamura, AJJ Wood, CM Stein. "Sildenafil potentiates the response to exogenous but not endogenous nitric oxide in the human dorsal hand vein." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

AA Ajayi, GG Sofowora , AQ Adigun. "Adjunctive Sympathoplegic Therapy to ACE Inhibitors in Blacks With Chronic Heart Failure: Alpha or Beta Blockade?" [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

HG Xie, GG Sofowora , V Dishy, RB Kim, AJJ Wood, CM Stein. "Beta-1 and Beta-2 Adrenergic Receptor (BAR) Polymorphism and Obesity in African American and Caucasian Americans." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

HG Xie, V Dishy, GG Sofowora , RB Kim, AJJ Wood, CM Stein. "Human Beta-1 Adrenergic Receptor (BAR-1) Polymorphism (Arg389Gly) is Not Associated with Essential Hypertension in Black or White Americans." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

V Dishy, GG Sofowora , H Imamura, HG Xie, CM Stein, AJJ Wood. "Nitric oxide production Decreases After Salt Loading But Does Not Predict Blood Pressure Responses." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

V Dishy, GG Sofowora , HG Xie, P Harris, AJJ Wood, CM Stein. "Arg389Gly B-1 Adrenoceptor Polymorphism does not Affect Agonist Mediated Responses In Vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2001) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, HG Xie, RB Kim, P Harris, M Mackanos, AJJ Wood, CM Stein. "Effect of Beta2 Adrenoceptor Polymorphisms on Homodynamic Responses to Exercise and Mental Stress." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2002) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, HG Xie, RB Kim, P harris, M Mackanos, H Prasad, AJJ Wood, CM Stein. "Beta-1 Adrenoceptor Genotype Affects Sensitivity to Beta Blocker." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2002) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, R Landau, R Smiley, HG Xie, RB Kim, AJJ Wood, CM Stein. "Effect of Alpha 1A Adrenergic Receptor Genotype on Vascular Response." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2002) [Peer Reviewed] (Published)

V Dishy, GG Sofowora , R Landau, HG Xie, WS Byrne,RM Smiley, AJJ Wood, CM Stein. "Balance of Adrenergic Vasoconstriction is Shifted Towards Enhanced Vasodilatation in Premenopausal Women." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2002) [Peer Reviewed] (Published)

GG Sofowora , M Muszkat, V Dishy, HC Prasad, AJJ Wood, CM Stein. "Increased Alpha1 Adrenergic Sensitivity in African Americans." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

GG Sofowora , M Muszkat, V Dishy, HG Xie, HC Prasad, AJJ Wood, CM Stein. "Endothelial Nitric Oxide Synthase Glu298Asp Polymorphism And Blood Pressure Responses to Salt." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

HC Prasad, V Dishy, GG Sofowora , M Muszkat, RB Kim, AJ Wood, CM Stein. "A Search For Inter-Individual Variability in Alpha1A Adrenergic Response." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

HG Xie, M Muszkat, GG Sofowora , R Landau, WM Cai, RB Kim, RM Smiley, CM Stein, AJJ Wood. "Ethnic Variability in the Frequency of Alpha Adrenergic Receptor Gene Polymorphism." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , AJ Wood, CM Stein. "Alpha2 Adrenergic Receptor Mediated Vascular Responses in African Americans And Caucasians." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , AJ Wood, CM Stein. "Effect of Alpha 2B Adrenergic Receptor 301-303 Deletion Polymorphism On Blood Pressure Response to Dietary Sodium." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , AJ Wood, CM Stein. "Regulation of Alpha2 Adrenergic Vascular Responses In Vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

V Dishy, R Landau, GG Sofowora , HG Xie, RM Smiley, RB Kim, DW Byrne, AJJ Wood, CM Stein. "Beta2 Adrenoceptor ILE 164 Polymorphism in Associated With Markedly Decreased Vasodilator and Increased Vasoconstrictor Sensitivity In Vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2003) [Peer Reviewed] (Published)

GG Sofowora , V Dishy, M Muszkat, HG Xie, HC Prasad, AJJ Wood, CM Stein. "Beta-2 Adrenergic Receptor Polymorphisms and Blood Pressure Responses to Salt." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2004) [Peer Reviewed] (Published)

HG Xie, R Landau, V Dishy, GG Sofowora , RM Smiley, RB Kim, AJJ Wood, CM Stein. "A Common Polymorphism in the adenyl Cyclase Type 9 Gene Does not Alter Responses to Isoproterenol." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2004) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , H Xie, AJJ Wood, CM Stein. "Alpha-2C Adrenergic Receptor 322-325 Deletion Polymorphism and In Vivo vascular sensitivity." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2004) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , H Xie, PA Harris, AJJ Wood, CM Stein. "Alpha-2B Adrenergic Receptor 301-303 Deletion Polymorphism and Vascular desensitization in Vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2004) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , V Dishy, HG Xie, PA Harris, AJJ Wood, CM Stein. "Effect of Alpha-2C Adrenergic Receptor 322-325 Deletion Polymorphism on Blood Pressure Response to Dietary Sodium in African-Americans." [Abstract]. Clinical Pharmacology and Therapeutics. (February 2004) [Peer Reviewed] (Published)

MA Shah, GG Sofowora , KL Nguyen. "Acute Adrenal crisis After a Steroid burst in a Patient With HIV Disease: A Case Report." [Abstract]. Journal of Allergy and Clinical Immunology. (February 2005) [Peer Reviewed] (Published)

D Kurnik, GG Sofowora , M Muszkat, PA Harris, AJJ Wood, CM Stein. "The Selective Alpha2 Adrenergic Receptor Agonist Dexmedetomidine does not Affect Aortic Pressure Augmentation." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2005) [Peer Reviewed] (Published)

HG Xie, V Dishy, GG Sofowora , AJJ Wood, RB Kim, CM Stein. "Adenylate Cyclase Type 9 (AC9) Polymorphism and in-vivo Vascular Response." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2005) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , D Kurnik, J Solus, L Jiang, SM Williams, E Dawson, AJ Wood, CM Stein. "Sequence Analysis of the Alpha2B Adrenergic Receptor (ADRA2B) Gene and in-vivo Functional Effects of Novel Variants." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2005) [Peer Reviewed] (Published)

M Muszkat, D Kurnik, GG Sofowora , JP Donahue, GR Wilkinson, AJ Wood. "Tariquidar (TAR, XR-9576) Selectively Inhibits P-glycoprotein (P-GP) in T-Lymphocytes Compared to That in the Blood-Brain Barrier (BB)." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2005) [Peer Reviewed] (Published)

EA Friedman, D Kurnik, M Muszkat, GG Sofowora , HG Xie, AJJ Wood, CM Stein. "Adrenergic Alpha2C- Receptor Genetic Variants Contribute to Ethnic Differences in Cardiovascular Responses to Stress." [Abstract]. Journal of Clinical Pharmacology. (2006) [Peer Reviewed] (Unspecified)

D Kurnik, EA Friedman, M Muszkat, GG Sofowora , HG Xie, PA Harris, AJ Wood, CM Stein. "Ethnicity and Systemic Effects of Dexmedetomidine, a Specific Adrenergic Alpha2 Receptor Agonist." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2006) [Peer Reviewed] (Published)

D Kurnik, M Muszkat, C Li, GG Sofowora , J Solus, HG Xie, PA Harris, L Jiang, C McMunn, P Ihrie, EP Dawson, SM Williams, AJ Wood, CM Stein. "Variations in the Alpha2A- Adrenergic Receptor Gene and their Functional Effects." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2006) [Peer Reviewed] (Published)

M Muszkat, GG Sofowora , D Kurnik, J Solus, L Jiang, SM Williams, EP Dawson, HG Xie, PA Harris, AJ Wood, CM Stein. "Variation in the Alpha2B- Adrenergic Receptor and its Relationship to Desensitization of Vascular Response In-Vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2006) [Peer Reviewed] (Published)

GG Sofowora , J Brennan, A Donato. "Factors Affecting Statin Refusal in Diabetics with Elevated Cholesterol." [Abstract]. American College of Physicians. (November 2006) [Peer Reviewed] (Published)

D Kurnik, GG Sofowora , EA Friedman, M Muszkat, HG Xie, PA Harris, L Jiang, SM Williams, C Li, AJJ Wood, CM Stein. "Beta1 Adrenoceptors and Ethnicity Independently Affect Response to Atenolol." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2007) [Peer Reviewed] (Published)

D Kurnik, M Muszkat, EA Friedman, GG Sofowora , HG Xie, PA Harris, L Choi, AJ Wood, CM Stein. "Effect of the Alpha2C- Adrenoceptor Deletion 322-325 on Sympathetic Activity And Cardiovascular Measures in Healthy Subjects." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2007) [Peer Reviewed] (Published)

U Kohli M Muszkat, GG Sofowora , EA Friedman, M Scheinin, AJ Wood, CM Stein, D Kurnik. "ADRA2C deletion 322-325- Effects on Pain Perception, Before and After Dexmedetomidine." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2008) [Peer Reviewed] (Published)

U Kohli, M Muszkat, GG Sofowora , EA Friedman, RF Tyndale, M Schieinin, AJ Wood, CM Stein, D Kurnik. "CYP2A6 Variants and Plasma Dexmedetomidine Concentrations." [Abstract]. Clinical Pharmacology and Therapeutics. (March 2008) [Peer Reviewed] (Published)

AJ Cunningham, C Li, GG Sofowora , EA Friedman, M Muszkat, U Kohli, UB Nair, AJJ Wood, CM Stein, D Kurnik. "Variability in Response to Beta-Blockade- The Effect of GRK5 Genetic Variation." [Abstract]. Clinical Pharmacology and Therapeutics. (January 2009) [Peer Reviewed] (Published)

M Muszkat, D Kurnik, GG Sofowora , HG Xie, AJJ Wood, CM Stein. "Independent Regulation of Alpha1 and Alpha2- Adrenergic Reception Mediated Vasoconstriction in vivo." [Abstract]. Clinical Pharmacology and Therapeutics. (January 2009) [Peer Reviewed] (Published)

U Kohli, A Diedrich, PJ Kannankeril, M Muszkat, GG Sofowora , CM Stein, D Kurnik. "Adrenergic Genetic Variation Affects Heart Rate Recovery After Exercise." [Abstract]. (January 2009) [Peer Reviewed] (Published)

U Kohli, MK Hahn, B English, M Muszkat, GG Sofowora , RD Blakely, CM Stein, D Kurnik. "Norepinephrine Transporter Polymorphisms Affect Blood Pressure Response to Exercise." [Abstract]. Clinical Pharmacology and Therapeutics. (January 2009) [Peer Reviewed] (Published)

 

Certifications

1996 - present Passed Part 1: West African College of Physicians

2003 - present Certified: Clinical Pharmacology, American Board of Clinical Pharmacology

2007 - 2017 Certified: Internal Medicine, American Board of Internal Medicine

2009 - present Certified: Nuclear Cardiology, Certification Board of Nuclear Cardiology

2009 - 2019 Certified: Echocardiography, National Board of Echocardiography

2010 - 2020 Certified: Cardiovascular diseases, American Board of Internal Medicine

 

Degrees

1989 M.B.,Ch.B, Obafemi Awolowo University

1994 M.Sc., University of Glasgow, Clinical Pharmacology

 

Fellowship, Internship or Residency

1989 - 1990 House Officer (Intern equivalent), Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.

1992 - 1996 Registrar (Resident equivalent), Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.

1996 - 1997 Senior Registrar (Chief Resident equivalent), Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.

09/97 - 06/00 Research Fellow, Clinical Pharmacology, Vanderbilt University, Nashville, TN, United States.

06/00 - 06/01 Intern, General Surgery, Vanderbilt University Medical Center, Nashville, TN, United States.

07/01 - 06/04 Research Fellow, Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, United States.

06/04 - 06/07 Resident, Internal Medicine, Reading Hospital and Medical Center, West Reading, PA, United States.

07/07 - 06/10 Fellow, Cardiology, Hahnemann University Hospital, Philadelphia, PA, United States.

 

Honors

1993 - 1994 British Chevening Scholarship Award.

1996 Sandoz Young Investigators Prize in Cardiovascular Research. Nigerian Cardiac Society.
Subject: Cardiovascular Research

1997 Fellow, Merck Sharp and Dohme International Fellowship in Clinical Pharmacology.

2002 Fellow, Presidential Trainee Award. American Society for Clinical Pharmacology and Therapeutics.

2005 Intern of the Year. Reading Hospital and Medical Center, West Reading, PA, United States.

2007 Resident of the Year. Reading Hospital and Medical Center, West Reading, PA, United States.

2007 Excellence in Teaching Award. Reading Hospital and Medical Center, West Reading, PA, United States.

 

Licensure

2010 - 2012 Ohio State Medical License: Ohio State Medical Board

 

Memberships

  Member. American Society of Echocardiography

  Member. American College of Cardiology

 

Peer Reviewed Journal Articles

Ajayi AA, Oluokun AR, Sofowora GG , Ajayi AT. "Epidemiology of Antimalarial Induced Pruritus in Africans."European Journal of Clinical Pharmacology. (1989)

Onayemi O, Sofowora GG , Osunkwo C, Okoro AN, Oyewo EA. "An open Non-comparative Pilot Study of the Safety and Efficacy of Fluconazole in the Treatment of Dermatophyte Infections in Nigeria." Nigerian Medical Practitioners. (1993)

Adamolekun B, Adamolekun WE, Sonibare AD, Sofowora GG . "A Double-blind, Placebo-controlled Study of the Efficacy of Thiamine Hydrochloride in a Seasonal ataxia in Nigerians."Neurology. (1994)

Ajayi AA, Sofowora GG , Balogun MO. "Concurrent ACE Inhibition an Alpha-1 Antagonism in the Treatment of Congestive Heart Failure." International Journal of Cardiology. (1996)

Ajayi AA, Sofowora GG , Balogun MO. "The Clinical Implications of the Inhibition of the 'Cross Talk' Between ACE Inhibitors and Alpha1-Adrenoceptor Blockers in Heart Failure."African Journal of Medicine and Medical Sciences. (1996)

Adebayo RA, Sofowora GG , Onayemi O, Udoh SJ, Ajayi AA. "Chloroquine Induced Pruritus in Malaria: Contribution of Malaria Parasitemia and Effects of Prednisolone, Niacin and the Combination Compared to Antihistamines."British Journal of Clinical Pharmacology. (1997)

Sofowora GG , Adigun AQ, Haastrup AT, Ajayi AA. "Study of Synergism Between Angiotensin Converting Enzyme Inhibitors and Adrenoceptor Blocker During Forearm Isometric Handgrip in Normal Man."Tropical Cardiology. (1998)

Adigun AQ, Ajayi OE, Sofowora GG , Ajayi AA. "Vasodilator Therapy of Hypertensive Acute Left Ventricular Failure: Comparison of Captopril-Prazosin with Hydralazine-Isosorbide Dinitrate."International Journal of Cardiology. (1998)

Ajayi AA, Olotu TC, Sofowora GG . "Knowledge, Attitudes and Practices of Prednisolone prevention of chloroquine induced pruritus among Nigerian health workers."Tropical Doctor. (1998)

Adigun AQ, Sofowora GG , Ajayi AA. "Chronotropic Atropine-Dose Response in Congestive Heart Failure: Assessment of Ethnic Variation and Reversibility of Parasympathetic Dysfunction."Ethnicity and Disease. (2000)

Xie HG, Stein CM, Kim RB, Sofowora GG , Dishy V, Gainer JV, Brown NJ, Haines JL, Wood AJJ. "Human Beta-2 Adrenergic Receptor Polymorphisms: No Association with Essential Hypertension in Black or White Americans."Clinical Pharmacology and Therapeutics. (2000)

Sofowora GG , Choo EF, Mayo G, Shyr Y, Wilkinson GR. "In vivo inhibition of CYP1A2 Activity by Oltipraz."Cancer Chemotherapy and Pharmacology. (2001)

Sofowora GG , Dishy V, Xie HG, Imamura H, Kim RB, Stein CM, Wood AJJ. "In Vivo Effects of the Glu298Asp Endothellal Nitric Oxide Synthase Polymorphism."Pharmacogenetics. (2001)

Dishy V, Sofowora GG , Kandcer M, Chan F, Wood AJJ, Stein CM. "The Effect of Sildenafil Citrate on Nitric Oxide-Mediated Responses."Clinical Pharmacology and Therapeutics. (2001)

Dishy V, Sofowora GG , Xie HG, Kim RB, Stein CM, Wood AJJ. "The Effect of Common Polymorphisms of the Beta2- Adrenergic Receptor on Agonist-mediated Vascular Desensitization."New England Journal of Medicine. (2001)

Xie HG, Dishy V, Sofowora GG , Kim RB, Landau R, Smiley RM, Zhou H, Wood AJJ, Stein CM. "Arg389Gly Beta1- adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo."Pharmacogenetics. (2001)

Sofowora GG , Dishy V, Muszkat M, Xie HG, Kim RB, Harris PA, Nair UB, Prasad HC, Wood AJJ, Stein CM. "A Common Beta 1 Adrenoceptor Genotype (Arg389Gly) Affects Sensitivity to Beta Blocker."Clinical Pharmacology and Therapeutics. (2003)

Ajayi AA, Sofowora GG , Adigun AQ, Asiyanbola B. "For the Patient New Treatments for Heart Failure in Black People Adjunctive Sympathoplegic Therapy to ACE Inhibition in Blacks With Congestive Heart Failure: A Comparison of Alpha-1 With Beta-1 Blockade On Exercise Tolerance and Cardiac Sympathovagal Reflex Activity."Ethnicity and Disease. (2003)

Ajayi AA, Sofowora GG , Adigun AQ, Asiyanbola B. "For the Sympathoplegic Therapy to ACE-inhibitors in Blacks with CHF: A comparison of Alpha with Beta-blockade on exercise tolerance and cardiac sympathovagal reflex activity."Ethnicity and Disease. (2003)

Dishy V, Sofowora GG , Imamura H, Xie HG, Stein CM, Wood AJJ. "Nitrio Oxide Production Decreases after Salt Loading but is not Related to Blood Pressure Changes or Nitric Oxide-mediated Responses."Journal of Hypertension. (January 2003)

Sofowora GG , Dishy V, Landau R, Smiley R, Xie HG, Prasad HC, Kim RB, Wood AJJ, Stein CM. "Alpha 1A Adrenergic Receptor polymorphism and Vascular Response."Clinical Pharmacology and Therapeutics. (2004)

Muszkat M, Sofowora GG , Wood AJJ, Stein CM. "Vascular Responses to an Alpha-2 Adrenergic Receptor Agonist, Dexmedetomidine in African-Americans and Caucasians."Hypertension. (January 2004)

Dishy V, Harris P, Pierce R, Prasad HC, Sofowora GG , Bonar HL, Wood AJJ, Stein CM. "Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers."British Journal of Clinical Pharmacology. (February 2004)

Dish V, Landau R, Sofowora GG , Xie HG, Smiley RM, Kim RB, Byrne DW, Wood AJJ, Stein CM. "Beta 2 Adrenoceptor Thri164lle Polymorphism is Associated with Markedly Decreased Vasodilator and Increased Vasoconstrictor Sensitivity in-Vivo."Pharmocogenetics. (August 2004)

Muszkat M, Sofowora GG , Xie HG, Wood AJJ, Stein CM. "Alpha 2B Adrenergic Receptor 301-303 Deletion Polymorphism and Vascular Alpha 2 Adrenergic Receptor Response." Pharmacogenetics & Genomics. (January 2005)

Sofowora GG , Singh I, He HB, Wood AJJ, Stein CM. "Effect of Acute Transdermal Estrogen on Basal, Mental stress and Cold Pressor-induced Sympathetic Responses in Postmenopausal women."Clinical Autonomic Research. (June 2005)

Muszkat M, Kurnik D, Solus J, Sofowora GG , Xie HG, Wood AJJ, Stein CM. "Variation in the Alpha2B Adrenergic Receptor Gene (ADRA2B) and its Relationship to Vascular Response In-vivo."Pharmocogenetics and Genomics. (June 2005)

Kurnik D, Muszkat M, Li C, Sofowora GG , Solus J, Xie HG, Harris PA, Jiang L, McMunn C, Ihrie P, Dawson EP, Williams SM, Wood AJJ, Stein CM. "Variations in the Alpha2A- Adrenergic Receptor Gene and Their Functional Effects in Caucasians and African Americans."Clinical Pharmacolology & Therapeutics. (March 2006)

Kurnik D, Muszkat M, Friedman EA, Sofowora GG , Xie HG, Harris PA, Choi L, Wood AJJ, Stein CM. "Effect of the Alpha2C - adrenoceptor deletion322-325 variant on cardiovascular measures and their ethnic differences in healthy subjects."Journal of Hypertension. (25 April 2007)

Kurnik D, Muszkat M, Sofowora GG , Friedman EA, Dupont WD, Scheinin M, Wood AJJ, Stein CM. "Ethnic and Genetic Determinants of Cardiovascular Response to the Selective Alpha2- Adrenergic Agonist; Dexmedetomodine." Hypertension. (February 2008)

Kurnik D, Friedman EA, Muszkat M, Sofowora GG , Xie HG, Dupont WD, Wood AJJ, Stein CM. "Genetic Variation in the Alpha2C- Adrenoceptor and G-Protein Contribute to Ethnic Differences in Cardiovascular Stress Responses." Pharmacogenetics and genomics. (18 September 2008)

Kurnik D, Li C, Sofowora GG , Friedman EA, Muszkat M, Xie HG, Harris PA, Williams SM, Nair UB, Wood AJJ, Stein CM. "Beta-1 - Adrenoceptor Genetic Variants and Ethnicity Independently Affect Response to Beta-Blockade." Pharmacogenetics and genomics. (18 October 2008)

Kurnik D, Sofowora GG , Donahue JP, Nair UB, Wilkinson GR, Wood AJJ, Muszkat M. "Tariquidar, a Selective P-glycoprotein Inhibitor, does not Potentiate Loperamide Opoid brain Effects in Humans Despite Full Inhibition of Lymphocyte P-glycoprotein." Anesthesiology 2008. (December 2008)

Kurnik D, Cunningham A, Sofowora GG , Kohli U, Li C, Friedman EA, Muszkat M, Menon UB, Wood AJ, Stein CM. "GRK5 Gin4Leu Polymorphism is not Associated with Sensitivity to Beta (1)- Adrenergic Blockade in Humans." Pharmacogenomics. (10 October 2009)

Muszkat M, Kurnik D, Sofowora GG , Solus J, Xie HG, Williams SM, Harris PA, Wood AJ, Stein CM. "Desensitization of Vascular Response in Vivo: Contribution of the Varioation in Alpha2B- Adrenergic Receptor Subtype." Journal of Hypertension. (5 January 2010)

Kohli U, Muszkat M, Sofowora GG , Harris PA, Friedman EA, Dupont WD, Scheinin M, Wood AJJ, Stein CM. "Effects of Variation in the Human Alpha (2A) and Alpha (2C)- Adrenoceptor genes on Cognitive Tasks and Pain Perception." European Journal of Pain. (5 February 2010)

Muszkat M, Kurnik D, Sofowora GG, Wood AJ, Stein CM. "Independent regulation of alpha-1 and alpha-2 adrenergic receptor-mediated vasoconstriction in vivo."Journal of Hypertension. (30 October 2010)

Muszkat M; Kurnik D; Sofowora GG; Wood AJ; Stein CM. Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo."Journal Of Hypertension. Vol. 29, no. 2. (1 February 2011): 251.

Kohli U; Hahn MK; English BA; Sofowora GG; Muszkat M; Li C; Blakely RD; Stein CM; Kurnik D. Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans."Pharmacogenetics And Genomics. Vol. 21, no. 4. (1 April 2011): 171.

 

Presentations

Other Presentations

Local

    Gbemiga Sofowora , Lecturer. "Evidence-Based Management of HTN in African-Americans: Impact of Genetics on Pharmacotherapy." Presented at Cardiovascular Diseases in African-Americans. Ohio State University. COlumbus, OH, 43210. (April 21, 2011) [Peer Reviewed]