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Mazzaferri, Ernest MD


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473 W 12th Ave
Columbus, OH 43210

Phone: (614) 247-7765

Email: mazzaferri.2@osu.edu

 

Current OSU Appointments

Associate Professor-Clinical, Cardiovascular Medicine

Physician, FGP-Cardiovascular Medicine

 

Clinical Interest

Cardiovascular Disease, Interventional Cardiology

Continuing Education, Extension, and Other Courses Taught

1) Co-Course Director: Acute Coronary Syndromes; Raising the Bar on Therapies and Outcomes, the Ohio State University; Yearly conference held at OSU in September from 2009-2012; Approximately 250-300 participants; Regional Conference with attendees from multi-state area. I participate in organization and development of conference agenda/speaker recruitment; I give at least one lecture and moderate several sessions each year.



2) Participate in various CME events and lectures throughout the year (as listed above)

Academic Advising

As listed above, I have collaborated with and mentored several house officers (both fellows and residents) in clinical cardiovascular research.

Academic Advising

2010 - present Gregory Comfort, Ohio State University Wexner Medical Center. Collaborating on a retrospective review of cardiology patients uundergoing Percutaneous Coronary Intervention in those with therapeutic INR's versus those with normal INR's.
2011 - present Kyle Pfahl, Ohio State University Wexner Medical Center. IRB exempt retrospective analysis. Objective: To determine the incidence of perioperative stent thrombosis for noncardiac surgeries at the Ohio State University Wexner Medical Center and to investigate a relationship between perioperative antiplatelet management and stent thrombosis. Data collected and currenlty undergoing analysis and review
2012 - present Nkechinyere Ijioma, Ohio State University Wexner Medical Center. IRB approved, investigator initiated randomized trial: Prospective, randomized clinical study: Ultrasound-guidance in improving femoral artery cannulation by first year cardiology fellows. IRB approval and are currently enrolling patients in this study. Our goal is to assess for more efficient ways to improve proficiency in femoral artery cannulation in first year cardiology fellows
2009 - 2010 Jason Evanchan The Ohio State University. Graduated 2010. "Recurrence of Acute Myocardial Infarction in Patients Discharged on Clopidogrel and a PPI after Stent Placement for AMI"; Evanchan J, Donnally M, and Mazzaferri Jr. EL; Clinical Cardiology; 2010 Mar;33(3):168-71
 

Books

Mazzaferri Jr E, Baliga R,. The Interventional Cardiologist's Perspective on Coronary CT-Angiography. Columbus, OH, US|USA: Lippencot; Cardiac CT Manual, January 2008.

Mazzaferri Jr E. Interventional Cardiology. Columbus, OH, US|USA: McGraw-Hill Co., January 2011.

Mazzaferri Jr E, Bayram M. Non-STEMI. Columbus, OH, US|USA: McGraw-Hill, January 2011.

Mazzaferri Jr E, Bayram M.. STEMI. Columbus, OH, US|USA: McGraw-Hill Co., January 2011.

 

Certifications

2006 - present Board Certification: American Board of Internal Medicine
- 2002 Board Certification: American Board of Internal Medicine
- 2005 Board Certification: American Board of Internal Medicine
 

Chapters in Books

Mazzaferri Jr. E.. "The Interventional Cardiologist's Perspective on Coronary CT-Angiography." In Cardiac CT Manual. -.

Mazzaferri Jr E. "Non-ST-Elevation Myocardial Infarction: A Review." In Cardiology Board Review Book. Edited by Baliga, R. -.

Bayram, M and Mazzaferri Jr E. "ST-Elevation Myocardial Infarction." In Cardiology Board Review Book. Edited by Baliga, R. -.

 

Clinical Services

07/01/2006 Interventional Cardiologist (OSU Ross Heart Hospital)
07/01/2006 Inpatient Heart 3 Service (OSU Ross Heart Hospital)
07/01/2006 Cardiovascular Outpatient Clinic (Stoneridge, Cardiovascular Medicine)

Clinical Trials

CoreValve Trial

SIMPLICITY-3

SAFE-PCI

SurTavi

ONLY trials listed are those for which I am/was SITE-PI

 

Degrees

1991 B.A., The Ohio State University

1999 M.D., The Ohio State University

 

Edited Books

Baliga, R. R. "Cardiology." Edited by Mazzaferri Jr E. New York: McGraw-Hill Medical, January 2011.

 

Editorial Activities

2009 - 2010 Section editor, Board Review Book
 

Honors

1996 Samuel J. Roessler Foundation Student Research Scholarship. Samuel J. Roessler Foundation.
1997 First Place Oral Presentation, Landacre Day Research Forum. The OSU Medical Center College of Medicine.
1999 - 2000 John A. Prior Award for Clinical Excellence. The OSU Medical Center Dept. of Internal Medicine.
2002 - 2003 Fellow of the Year. University of Florida.
2005 Certificate of Appriciation. Dept. of Veteran Affairs, North Florida/South Georgia Veterans Health System.
2008 - 2009 Business First Health Care Heroes Award. Business First.
2009 Best Doctors. Columbus Monthly Magazine.
2009 - 2010 Healthcare Heroes Award. Business First.
2010 Best Doctors. Columbus Monthly Magazine.
2010 Charles F Wooley Teaching Award, Ohio State Division of Cardiovascular Medicine. OSU Division of Cardiovascular Medicine.
2010 Cardiovascular, Division II Block Faculty Award. The Integrated Pathway Program.
2010 - 2011 Teaching Excellence Award. The Department of Internal Medicine.
2011 Best Doctors. Columbus Monthly Magazine.
2011 Teaching Excellence Award. Department of Internal Medicine.
2012 Best Doctors. Columbus Monthly.
2012 - 2013 AHA Great Rivers Affiliate Distinguished Service Award. American Heart Association.
 

Journal Articles

Marsh,C,B; Pomerantz,R,P; Parker,J,M; Winnard,A,V; Mazzaferri Jr E,L; Moldovan,N; Kelley,T,W; Beck,E; WEWERS,M,D. "Regulation of monocyte survival in vitro by deposited IgG: Role of macrophage colony-stimulating factor." JOURNAL OF IMMUNOLOGY. Vol. 162, no. 10. (May 1999.): 6217-6225.

Mazzaferri Jr E. "Changing Patterens of CAD Therapy and Hormone Usage for Women." Cardiology Review. Vol. 22, no. 3. (January 2005.): 32-39.

Doshi, A.A., Orsini, A.R., Mazzaferri Jr Ernest, Schidt, W. T., Magorien, R.D.. "Drug eluting stent implantation for the treatment of symptomatic myocardial bridging is associated with favorable peri-procedural results and short-term outcomes." International Journal of Cardiology. Vol. 118, no. 3. (January 2007.): e87-e88.

Mazzaferri Jr E, Young JJ. "Abciximab: a review and update for clinicians." Cardiovascular Ther.. Vol. 5, no. 6. (January 2008.): 609-618.

Evanchan,Jason; Donnally,Michael,R; Mazzaferri Jr Ernest. "Recurrence of Acute Myocardial Infarction in Patients Discharged on Clopidogrel and a Proton Pump Inhibitor After Stent Placement for Acute Myocardial Infarction." CLINICAL CARDIOLOGY. Vol. 33, no. 3. (March 2010.): 168-171.

Raman,Subha,V; Simonetti,Orlando,P; Winner,Marshall,W; Dickerson,Jennifer,A; He,Xin; Mazzaferri Jr Ernest; Ambrosio,Giuseppe. "Cardiac Magnetic Resonance With Edema Imaging Identifies Myocardium at Risk and Predicts Worse Outcome in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Vol. 55, no. 22. (June 2010.): 2480-2488.

Mazzaferri, Jr E, Gardinac SS, Otasevic P, Hasan AK, Goff TL, Sievert H, Wunderlich N, Nikolic SD, Abraham WT. "Percutaneous Left Ventricular Partitioning in Patients with Chronic Heart Failure and a Prior Anterior Myocardial Infarction: Results of the Percutaneous Ventricular Restoration in Chronic Heart Failure Patients Trial." American Heart Journal. Vol. 163, no. 5. (May 2012.): 812-820.

Boudoulas,Konstantinos,Dean; Pederzolli,Andrew; Saini,Uksha; Gumina,Richard,J; Mazzaferri,Ernest,L; Davis,Michael; Bush,Charles,A; Capers,Quinn; Magorien,Raymond; Pompili,Vincent,J. "Comparison of Impella and intra-aortic balloon pump in high-risk percutaneous coronary intervention: vascular complications and incidence of bleeding.." Acute cardiac care. Vol. 14, no. 4. (December 2012.): 120-124.

Mazzaferri Jr E, Kereiakes, DJ. "The Truth and Consequences of the C-PORT E Trial." Cardiology Today Intervention. Vol. 1, no. 4. (July 2012.): 6-9.

Mazzaferri Jr E; Rao Sunil. "Cardiogenic Shock and Awe." CARDIOLOGY. Vol. 121, no. 1. (January 2012.): 43-46.

Boudoulas KD, Bowen T, Pederzolli A, Pfahl K, Pompili VJ, Mazzaferri EL Jr.. "Duration of intra-aortic balloon pump use and related complications.." Acute Cardiology Care. Vol. Unknown, (March 2014.): Unknown-.

 

Reference Works

January 2009 Mazzaferri Jr E, and Abraham W.."Percutaneous Therapy for Ischemic Heart Failure: Long Term Safety and Efficacy in 33 patients" Unknown.
Quinn Capers IV, Ernest L Mazzaferri Jr, Charles A Bush, Randy Allen,."Same Day Discharge vs Overnight Stay After Transradial PCI Results in Equivalent Safety with Significant Cost Savings/Increased Margin for the Hospital" .
Mazzaferri Jr E."Percutaneous Left Ventricular Partitioning for Ischemic Heart Failure: Results of the US-PARACHUTE Feasibility Study" .
Maehara A, Mintz G, Witzenbichler B, Metzger C, Rinaldi M, Mazzaferri Jr E, Duffy P, Weisz G, Stuckey T, Brodie B, Parise H, Mehran R, Stone GW."Intravascular Ultrasound (IVUS) Sub-Study Results from the Assessment of Dual AntiPlatelet THerapy with Drug Eluting Stents (ADAPT-DES) Study: Grayscale and VH-IVUS Predictors of DES Thrombosis" .
Quinn Capers IV, Ernest L Mazzaferri Jr., Raymond D. Magorien, Aaron Bagnola, Danielle Blais, Vincent Pompili."Transradial Approach to STEMI Intervention at Ohio State University: Clinical Results of a Protocol to Minimize Transradial D2B times" .
Hiram Bezerra1, Sinisa Gradinac, Ernest Mazzaferri Jr, Horst Sievert, Igor Gregoric, Charles Davidson, Peter Berger, Albrecht Elsässer, Ron Waksman, Frank Smart, William Albernathy, William Abraham, Marco Costa."Multi-slice Computer Tomography Analysis of Percutaneous Ventricular Restoration (PVR) using the Parachute Device in Patients with Heart Failure Post Anterior Wall Myocardial Infarction: First-In-Man Experience" .
Mazzaferri Jr E, Hasan A, Abraham WTq."2 Year Update on VPD Implant Patient" .
Marco Costa, Martyn Thomas, Hüseyin Ince, Christoph Nienaber, Andrejs Erglis, Sinisa Gradinac, Vasco Gama, Rui Ferreira, Ernest Mazzaferri Jr, Horst Sievert, Igor Gregoric, Charles Davidson, Peter Berger, Albrecht Elsässer, Ron Waksman, Frank Smart, William Albernathy, William Abraham."Acute and 6-Month Clinical and Echocardiographic Outcomes of the First-In-Human Experiences with the Implantation of a Novel Catheter-based Ventricular Partitioning Device in Patients with Ischemic Heart Failure and Dilated Left Ventricle" .
Thomas Stuckey, Ajay J. Kirtane, Helen Parise, Bernhard Witzenbichler, Giora Weisz, Michael Rinaldi, Franz-Josef Neumann, Chris Metzger, Timothy Henry, David Cox, Peter Duffy, Bruce Brodie, Ernest Mazzaferri Jr, Ecaterina Cristea, Roxana Mehran, Gregg W. Stone."Lack of Association Between On-Treatment Platelet Reactivity and Ischemic Outcomes in Diabetic Patients: One Year Results of The ADAPT-DES Study" .
Stuckey T, Kirtane AJ, Parise H, Witzenbichler B, Weisz G, Rinaldi M, Neumann F, Metzger C, Henry T, Cox D, Duffy P, Brodie B, Mazzaferri Jr E, Cristea E, Mehran R, Stone GW."Impact of Point-of-Care platelet Function Testing Among Diabetic and Non-Diabetic Patients Undergoing PCI with Drug-Eluting Stents" .
Shinji Inaba, Gary S. Mintz, Bernhard Witzenbichler, Christopher Metzger, Michael Rinaldi, Ernest Mazzaferri Jr, Peter Duffy, Giora Weisz, Thomas Stuckey, Bruce Brodie, Ke Xu, Roxana Mehran, Gregg W. Stone, Akiko Maehara."Myocardial bridging does not affect atherosclerosis in adjacent coronary artery segments: An ADAPT-DES IVUS sub-study" .
Michael Rinaldi, Ajay J. Kirtane, Helen Parise, Bernhard Witzenbichler, Giora Weisz, Franz-Josef Neumann, Chris Metzger, Timothy Henry, David Cox, Peter Duffy, Bruce Brodie, Thomas Stuckey, Ernest Mazzaferri Jr, Ecaterina Cristea, Roxana Mehran, Gregg W. Stone."Impact of Point-of-Care Platelet Function Testing Among Patients with and Without Acute Coronary Syndromes Undergoing PCI with Drug-Eluting Stents: An ADAPT-DES Substudy" .
; Marco Costa1, Sinisa Gradinac, Ernest Mazzaferri Jr, Horst Sievert, Igor Gregoric, Charles Davidson, Peter Berger, Albrecht Elsässer, Ron Waksman, Frank Smart, William Albernathy, William Abraham."Three-year Clinical Outcomes of the First-In-Human Experience with Percutaneous Ventricular Restoration Using the Parachute Device in Patients with Ischemic Heart Failure and Dilated Left Ventricle" .
Kyeong Ho Yun, Gary S. Mintz, Bernhard Witzenbichler, Christopher Metzger, Michael Rinaldi, Ernest Mazzaferri Jr, Peter Duffy, Giora Weisz, Thomas Stuckey, Bruce Brodie, Ke Xu, Roxana Mehran, Gregg W. Stone, Akiko Maehara."Relationship between platelet reactivity and culprit and non-culprit lesion morphology: The ADAPT-DES IVUS substudy" .
Akiko Maehara, Gary Mintz, Bernhard Witzenbichler, D. Christopher Metzger, Michael Rinaldi, Ernest Mazzaferri Jr, Peter Duffy, Giora Weisz, Thomas Stuckey, Bruce Brodie, Ke Xu, Helen Parise, Roxana Mehran, Gregg Stone."IVUS Predictors of Stent Thrombosis: Results From the Prospective, Multicenter ADAPT-DES Study" .
Ajay J. Kirtane, Thomas Stuckey, Ke Xu, Bernhard Witzenbichler, Giora Weisz, Michael Rinaldi, Franz-Josef Neumann, Chris Metzger, Timothy Henry, David Cox, Peter Duffy, Bruce Brodie, Ernest Mazzaferri Jr, Ecaterina Cristea, Helen Parise, Roxana Mehran, Gregg W. Stone."Is There a Therapeutic Window For Platelet Responsiveness Among PCI Patients? Analysis from the ADAPT-DES Study;" .
Kirtane AJ, Parise H, Witzenbichler B, Weisz G, Rinaldi M, Neumann F, Metzger C, Henry T, Cox D, Duffy P, Brodie B, Stuckey T, Mazzaferri Jr E, Cristea E, Mehran R, Stone GW."Does Platelet Function testing add Significant Incremental Risk Strarification to Unselected Patents Undergoing DES Implantation?" .

Presentations

"Sudden Cardiac Death in Young Athletes." Presented at Ohio State University, . (June 2002)

"Sudden Cardiac Death in Young Athletes." Presented at University of Florida, . (May 2003)

"Cardiac Sarcoidosis, Case Presentation and Discussion." Presented at University of Florida Felows Reunion 2003, Gainesville. (September 2003)

"Novel Therapies in Cardiac Catheterization: An Update on Distal Protection Devices." Presented at Unknown, . (December 2003)

"Cardiac Sarcoidosis Case Presentation and Discussion." Presented at Conference, . (September 2003)

"Novel Therapies in Cardiac Catheterization: An Update on Distal Protection Devices." Presented at Unknown, Leesburg. (December 2003)

"Cardiac Transplantation - Coronary Allograft Rejection and Coronary Allograft Vasculopathy." Presented at University of Florida, . (June 2004)

"Grand Rounds." Presented at Cardiology Grand Rounds, FL, US|USA. (June 2004)

"REVEAL and PARACHUTE: Novel Trials in the Cardiac Catheterization Laboratory." Presented at Cardiology Grand Rounds, Columbus, OH. (May 2006)

"Cardiovascular Risk: What you should know about your risk and how to prevent it." Presented at The Dublin/Worthington Rotary Club of Ohio, Dublin, OH. (July 2006)

"STEMI Alert: Pathophsiology to Bedside." Presented at Mary Rutan Hospital, Bellefontaine, OH, US|USA. (November 2008)

"STEMI." Presented at Heart of it All 2008, Columbus, OH, US|USA. (November 2008)

"Proxis Animal Lab." Presented at St. Jude Medical S.C., Columbus, OH, US|USA. (November 2008)

"Embolic Protection." Presented at Current Techiques in Proximal Embolic Protection, Columbus, OH, US|USA. (August 2008)

"Distal Embolic Protection in complex PCI." Presented at Cardiology CE Conference, Athens, GA, US|USA. (September 2008)

"Myocardial Protection During Saphenous vein Graft Interventions." Presented at Cardiac Catheterization Conference, Detroit, MI, US|USA. (April 2008)

"Angioplasty and Coronary Stenting." Presented at The Ohio State University Medical center MEDNET Live Webcast, Columbus, OH, US|USA. (April 2008)

"Myocardial Protection During Saphenous VEin Graft Intervention." Presented at Cardiac Catheterization Conference, Detroit, MI, US|USA. (April 2008)

"Myocardial Protection During Saphenous Vein Graft Intervention." Presented at Grand Rounds, Greensburg, PA, US|USA. (May 2008)

"Percutaneous Interventionion vs Coronary Artery Bypass Grafting: Debate." Presented at Easton Town Center Lecture, Columbus, OH, US|USA. (June 2008)

"PARACHUTE: First United States Implant." Presented at ACC/SCAL, Chicago, IL, US|USA. (March 2008)

"Cardiovascular Perioperative Risk Assessment." Presented at Mount Carmel Grand Rounds, Columbus, OH, US|USA. (December 2008)

"Panel Discussion: Reshaping the Failing Heart." Presented at TCT (Transcatheter Cardiovascular Therapeutics), San Francisco, CA. (September 2009)

"Update on STEMI and the OSU STEMI program." Presented at Wyandot Memorial Hospital Grand Rounds, Wyandot, OH, US|USA. (November 2009)

"Cath vs. CABG Round II." Presented at Heart of it All 2009, Columbus, OH, US|USA. (November 2009)

"STEMI." Presented at The Ohio State University's Contemporary Multi-Disciplinary Cardiovascular Medicine, Orlando, FL, US|USA. (October 2009)

"Grand Rounds." Presented at South Eastern Ohio Regional Medical Center, Cambridge, OH, US|USA. (August 2009)

"CardioKinetics Left Ventricular Partitioning: Long-Term Safety and Efficacy." Presented at TCT (Transcatheter Cardiovascular Therapeutics), San Francisco, CA, US|USA. (September 2009)

"Parachute: World-wide results of First in Man Ventricular Partitioning Device." Presented at Congenital & Structural Interventions 2010, Frankfurt, DE|DEU. (July 2010)

"Update on Acute Coronary Syndrome, STEMI." Presented at Ohio State University MEDNET live Webcast, . (October 2010)

"Myocardial Infarction." Presented at Acute Myocardial Infarction: Raising the Bar on Therapies and Outcomes 2010, Columbus, OR, US|USA. (September 2010)

"STEMI." Presented at Acute Myocardial Infarction: Raising the Bar on Therapies and Outcomes 2011, Columbus, OH, US|USA. (September 2011)

"STEMI 2012: A Changing Paradigm." Presented at Blanchard-Valley Regional Medical Center Grand Rounds, Findlay, Ohio, Findlay, OH, US|USA. (February 2012)

"What's New in STEMI: An Update on Guidelines and Novel Therapies." Presented at 4th Annual Acute Myocardial Infarction Update: Beyond STEMI - An introduction to a Level 1 Heart & Vascular Program, Columbus, OH, US|USA. (September 2012)

"Management of Hypertension: The Role of Non-Pharmacologic Therapies/Renal Denervation." Presented at Ohio State University’s Regional Advance Concepts in Electrophysiology (RACE) Program, . (November 2012)

"Plumbing in the 21st Century: An Update on Novel Therapies in teh Cardiac Catheterization Lab." Presented at Mended Hearts of Central Ohio, Columbus, Ohio. (January 2012)

 

Professional Activities

present 2012 Press Ganey Executive Leadership Conference. Press Ganey. National Harbor, MD.
present UH/Ross Supervisory Council Retreat. The Ohio State University Wexner Medical Center. Columbus, OH.
present Chairperson, STEMI White Paper, Central Ohio. Central Ohio Trauma Association.
present Attendee; Press Ganey National Conference. Press Ganey Institute.
present Leadership Strategies for Evolving Health Care Executives;. Harvard School of Public Health. Boston, MA.
2009 - present Co-Chair, Hospital Work Group, Ohio Mission Lifeline. American Heart Association.
2010 - present Presentation to Fraternal Order of Eagles. Fraternal Order of Eagles. Columbus, OH.
2007 Richard M. Ross Heart Hospital and Fischer College of Business Leadership Seminar. Richard M. Ross Heart Hospital and Fischer College of Business.
2009 ACC: Emergency Cardiovascular Care 2009. American College of Cardiology. Chicago, IL.
2010 CSI Meeting. Cardiac and Structural Interventions Meeting. Frankfurt, Frankfurt, Germany.
2010 Innovation in Care Coordination Panel. OSU Medical Center Senior Leadershio Retreat. Columbus, OH.
2011 Senior Leader Retreat. The Ohio State University. Columbus, OH.
2011 ACC 2011. New Orleans, LA.
2011 American Heart Association Scientific Session 2011. The American Heart Association. Orlando, FL.
2011 Transradial Cath Lab Training. Philadelphia, PA.
2010 - 2012 American Heart Association National STEMI Science Advisory Task Force. American Heart Association.