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Glen Cooke, MD 530 Davis Heart and Lung Institute glen.cooke@osumc.edu
Research Interests:
- Genetics of heart disease
- Platelet integrin function and thrombosis
- Pharmacogenetics of cardiovascular disease
Richard Gumina, MD, PhD 370 Biomedical Research Tower richard.gumina@osumc.edu
Research Interests:
- Role of the sarcolemmal KATP channel in myocardial ischemia-reperfusion injury
- Role of platelets in myocardial ischemia-reperfusion injury
- Cardioprotective efficacy of novel Na-H exchange inhibitors
- Assessment of cardioprotective efficacy of adjunctive therapy in ACS
- Clinical outcomes in elective and urgent PCI - role of GP IIb/IIIa antagonists
- Clinical outcomes in high-risk PCI supported with the TandemHeart Assist device
Sampath Parthasarathy, PhD 350 Biomedical Research Tower spartha@osumc.edu
Research Interests:
- Molecular mechanisms of atherosclerotic calcification
- Azelaic acid, a long chain dicarboxylic acid derived from lipid peroxidation as a myocyte calcium sequestrant
- Role of mitochondria in diabetic hypertriglyceridemia
- Macrophage adherence and gene experssion
- Plaque stabilization using unusual antioxidants
- Inflammatory lipoproteins
- Aspirin as an inducer of paraoxonase 1 (PON 1)-clinical trial
- Natural PPAR alpha ligand-Ox FFA
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